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Search Results: 1 - 10 of 8794 matches for " Germain Marie Monespérance Mboudou "
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Characterization of Alluvial Gold Bearing Sediments of Betare Oya District-East Cameroon, Implication for Gold Exploration and Recovery  [PDF]
Germain Marie Monespérance Mboudou, Kennedy Folepai Fozao, Olivier Annoh Njoh, Christopher Mbaringong Agyingi
Open Journal of Geology (OJG) , 2017, DOI: 10.4236/ojg.2017.711115
Abstract: Field studies (location Au pits, sampling of different layers of sedimentary sequences filling the pits, panning of sediments), litho-stratigraphic investigations, grain size analysis and outlining of depositional conditions revealed a characteristic fining upward sequence in all the sections of 08 Au-pits within the Betare Oya basin. A typical profile is 2.5 to 4.5 m thick and is composed of a 30 to 50 cm organic topsoil layer, underlain by a 1.5 m thick reddish brownish gold free saprolite, which is underlain by 1.5 m sandy section. From litho-stratigraphic investigations and grain size analysis results a quartz dominated gravelly 1.4 m thick layer consisting in boulders (275 mm), cobbles (2-<20 mm) and subrounded pebbles (28 - 38 mm) mixed with sand grains (0.9 - 1.5 mm) and silt (0.01 - 0.02 mm). Pyrite, chalcopyrite and arsenopyrite are minor minerals and could be referred as to Au pathfinders (As, Fe, Cu). This layer overlays paleo-Proterozoic basement rocks (Nyong series) and is overlain by a poorly sorted sandy layer containing rounded whitish quartz grains and plagioclase fractions (Ca, Na), minor silts (0.02 - 0.2 mm), gravel and feldspar (K) leached from granitic plutons along shear zones in the area. The saprolite horizon overlaying the sandy layer derives from weathering and leaching of basement rocks under warm-humid climatic conditions. From gold grain count, the gravelly layer is the main productive horizon. Its upper layer (0.5 m) yields 02 Au grains per Kg of sampled materials while the 1 m-tick lower layer contains up to 34 Au-grains per sample and 13 g rains in 1 Kg of sampled materials. The sandy layer follows with averagely 02 Au grains per Kg as indication of partial leaching of primary mineralized rocks. Au concentration at depth (sandy and gravelly layers) is due to physical and chemical remobilization of Au in the secondary environment of deposition. Au is lithologically controlled and could be an important exploration factor in the study area. The calculated aspect ratios for pebbles from the gravelly and sandy layers disclosed two polynomial trends: 1) y = 0.0148x2 + 1.2187x + 2.0344, R2 = 0.6929 (sandy layer); 2) y = 0.0617x2 + 1.0849x + 0.8097, R2 = 0.8694 (gravelly layer); and y > R2 is satisfied in both cases. This implies that Au recovery from these layers could be effective
Geochemical Characterization of Novokrivoyrog Metavolcanics: Tectonic Implications and Relationship with the Early Proterozoic Banded Iron Formation (BIF) of Krivoy Rog in Ukraine  [PDF]
Germain M. M. Mboudou, Cheo E. Suh, George T. Mafany
Open Journal of Geology (OJG) , 2012, DOI: 10.4236/ojg.2012.23013
Abstract: The geochemical characterization of Novokrivoyrog metavolcanics (2.2 Ga) and Krivoy Rog iron ores (1.8 Ga) in Ukraine represent an important tool for the understanding of their genesis and tectono-magmatic evolution. The petrological classification of the metavolcanics on SiO2/(Zr-TiO2) and (Zr-TiO2)/(Nb/Y) Harker-type diagrams shows similarities to subalkaline andesitic basalts. An additional classification of the basalts on TAS (Na2O + K2O/SiO2) and AFM (FeO-MgO-Na2O + K2O) diagrams exhibits a variable magmatic character from calc-alkaline to tholeiitic. The distribution of High Field Strength Elements, (HSFE: Ti, Zr, Y, Hf, Nb), V, Cr, and Rare Earth Elements (REE) in most of the rocks is close to calc-alkaline basalts (CAB) and can be compared to Precambrian mid-ocean ridge basalts (MORB) where high thermal (>250°C) basaltic alteration is intensive under pH conditions between 2 and 4. These contributed to the deposition of the Krivoy Rog BIFs. Indeed REE distribution patterns of the BIFs suggest that they can be subdivided into shales and shaly BIFs (rich in LREEs since their detrital and clastic inputs are much higher) with (La/Yb)N > 1 as indication of clastic inputs; chert and cherty BIFs showing positive Eu anomaly with (La/Yb)N < 1 are similar to REE patterns of mixed hydrothermal fluids and seawater; alkaline altered BIFs whose (La/Yb)N ratio is >1 emphasizes post-depositional effects related to the enrichment of light REEs over heavy REEs with a positive Eu anomaly. The distribution of REE patterns of Krivoy Rog BIFs can finally be compared to Precambrian iron formations of mixed submarine hydrothermal fluids and seawater origin which correspond to the MORB signature of the Novokrivoyrog metavolcanics.
Carbonate Enrichment in Volcanic Debris and Its Relationship with Carbonate Dissolution Signatures of Springs in the Sabga-Bamessing, North West, Cameroon  [PDF]
Raymond Beri Verla, Germain M. M. Mboudou, Olivier Njoh, Gilles Nyuyki Ngoran, Aloysius Ngambu Afahnwie
International Journal of Geosciences (IJG) , 2014, DOI: 10.4236/ijg.2014.51012
Abstract:

Sabga-Bamessing is a part of the Bamenda Mountains, an extinct volcanic center of the West Cameroon Highlands along the Cameroon Volcanic Line (CVL). The pristine volcanic rocks of the Sabga area are alkali mafic to felsic (basanites, phonolites, trachytes and rhyolites). Some weathered sections of a heterolithologic debris flow with a suppositious primary chemistry of the original volcanic rocks prior to weathering have shown significant calcium carbonate enrichment. CaO and LOI values of up 61.31% and 41.72% respectively show corresponding enrichment of 16.54 and 10.88, when compared with average fresh volcanic rocks. Na+ normalized molar ratios computed from the chemistry of springs and rivers show carbonate dissolution signature which is contrary to silicate dissolution expected in acid volcanic rocks. Saturation indices (SI) calculated with PHREEQC reveal that brackish to saline springs are supersaturated with Calcite (CaCO3), Aragonite (CaCO3), Dolomite (CaMg(CO3)2 and Hydroxyl apatite (Ca5(PO4)3OH). Recharging contributions to spring water chemistry deviate from those produced by rock weathering, precipitation and evaporation/crystallization. An enrichment process

Sedimentology and Geochemical Evaluation of Lignite-Argillite Sequences in a Named Basin in Bali Nyonga, Northwest, Cameroon  [PDF]
Roger Ngong Ngia, Christopher M. Agyingi, Josepha Foba-Tado, Germain M. M. Mboudou, Anita Nshukwi, Victorine N. Beckley
International Journal of Geosciences (IJG) , 2015, DOI: 10.4236/ijg.2015.68074
Abstract: The sedimentology and geochemistry (major and trace element compositions) of lignite and argillite (carbonaceous shale and claystone) sequences in a Basin in Bali Nyonga, west of the Bamenda Mountain have been investigated to determine their sequences and the prevailing environmentalconditions which control their formation. Ten representative samples were obtained fromtrenches, pits, and river and stream valleys in the study area. These samples and their ashes were subsequently examined using X-ray fluorescence spectrometry (XRF), inductively coupled plasma spectrometry (ICP), and X-ray diffraction analysis (XRD). The geochemical results revealed that thelithophile, chalcophile and siderophile elements were dominantly epigenetic in origin, mainlyfrom detrital sources supported by high silica and alumina concentrations in all the samples. The mineral phases identified were quartz, kaolinite, illite, pyrite, hematite, and minor phases of feldspars,pseudorutile. The relatively high silica (54.10 wt%) and alumina contents (27.77 wt%) in thesesamples can be explained by high detrital input during peat formation. The low contents of MgO and CaO in the analysed samples agree very much with the continental setting of the peat formating basin. A clayey microband derived from alkaline volcanic ashes was identified in the lignite and the dominant composition of these clayey microbands was mixed-layer clay minerals of illite and kaolinte, which were interlayered with organic bands. The modes of occurrence of ash bands indicated that the volcanic activities were characterized by multiple eruptions, short time intervaland small scale for each eruption during peat accumulation. The ratios of redox-sensitive traceelement (V/Cr versus Ni/Co and V/V + Ni versus Ni/Co), Sr/Ba, and major oxides ratio (CaO + MgO + Fe2O
Hospital-Acquired Anaemia Secondary to Phlebotomy in Elderly Patients  [PDF]
Divya Tiwari, Caroline Rance
Advances in Aging Research (AAR) , 2014, DOI: 10.4236/aar.2014.32012
Abstract:


Introduction: Anaemia contributes to increased morbidity and mortality in hospitalised patients, yet unnecessary blood tests from inpatients may actually induce a “hospital acquired anaemia” (HAA). This study examines the incidence of phlebotomy-induced anaemia during a hospital admission. Methods: Patients admitted to the Royal Bournemouth Hospital between 2009 and 2011 for a period of more than two weeks were identified. Those with normal haemoglobins on admission (Hb > 130 g/dL in men; Hb > 120 g/dL in women) were selected to be included in the study. One hundred and sixty two patients were randomly selected from this group and their admission and discharge haemoglobin was recorded, and the change in Hb was calculated. The number of blood tests taken during admission was calculated from each patient from which volume of blood lost was determined. Age, sex and co-morbidities, bleeding complications and blood transfusions were noted. T-test for unequal variance was used for analysis. Results: Of the 162 patients, 69 (42.5%) developed a HAA (defined as haemoglobin drop from normal to <110 g/dL). The average number of blood tests taken in the anaemia group was 37, compared to only 23 in the “no-anaemia” group. i.e. 132 mls in the anaemia group vs. only 80.2 mls in no-anaemia group. Further analysis of the anaemia group revealed that 40 patients developed a “mild anaemia” (defined as drop in Hb from normal to <110 g/dL) and 29 developed a moderate/severe anaemia (drop from a normal Hb at admission to <100 g/dL). Significantly higher volume of blood was withdrawn from this moderate/severe anaemia group compared to those that developed a mild anaemia 177.9 mls vs. 121.34 mls (p-Value 0.007, F = 0.001) 95% CI 2.08 to 9.22. Conclusion: This study suggests that patients admitted for inpatient stays of more than two weeks may be at high risk of HAA as a consequence of diagnostic blood loss. This anaemia in turn may have detrimental consequences, especially in patients with pre-existing cardio-respiratory disease. There needs to be increased awareness of the risk posed to patients as a result of diagnostic phlebotomy and further studies are required to study its impact on LOS, morbidity and mortality outcomes.

Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids
Sylvain L'Espérance, Magdalena Bachvarova, Bernard Tetu, Anne-Marie Mes-Masson, Dimcho Bachvarov
BMC Genomics , 2008, DOI: 10.1186/1471-2164-9-99
Abstract: Exposure of OC spheroids to these CT drugs resulted in differential expression of genes associated with cell growth and proliferation, cellular assembly and organization, cell death, cell cycle control and cell signaling. Genes, functionally involved in DNA repair, DNA replication and cell cycle arrest were mostly overexpressed, while genes implicated in metabolism (especially lipid metabolism), signal transduction, immune and inflammatory response, transport, transcription regulation and protein biosynthesis, were commonly suppressed following all treatments. Cisplatin and topotecan treatments triggered similar alterations in gene and pathway expression patterns, while paclitaxel action was mainly associated with induction of genes and pathways linked to cellular assembly and organization (including numerous tubulin genes), cell death and protein synthesis. The microarray data were further confirmed by pathway and network analyses.Most alterations in gene expression were directly related to mechanisms of the cytotoxics actions in OC spheroids. However, the induction of genes linked to mechanisms of DNA replication and repair in cisplatin- and topotecan-treated OC spheroids could be associated with immediate adaptive response to treatment. Similarly, overexpression of different tubulin genes upon exposure to paclitaxel could represent an early compensatory effect to this drug action. Finally, multicellular growth conditions that are known to alter gene expression (including cell adhesion and cytoskeleton organization), could substantially contribute in reducing the initial effectiveness of CT drugs in OC spheroids. Results described in this study underscore the potential of the microarray technology for unraveling the complex mechanisms of CT drugs actions in OC spheroids and early cellular response to treatment.Ovarian cancer (OC) is the fourth commonest cause of cancer related death in women [1]. The majority of patients present with advanced disease, with an over
The National DNA Data Bank of Canada: a Quebecer perspective
Emmanuel Milot,Marie M. J. Lecomte,Hugo Germain,Frank Crispino
Frontiers in Genetics , 2013, DOI: 10.3389/fgene.2013.00249
Abstract: The Canadian National DNA Database was created in 1998 and first used in the mid-2000. Under management by the RCMP, the National DNA Data Bank of Canada offers each year satisfactory reported statistics for its use and efficiency. Built on two indexes (convicted offenders and crime scene indexes), the database not only provides increasing matches to offenders or linked traces to the various police forces of the nation, but offers a memory repository for cold cases. Despite these achievements, the data bank is now facing new challenges that will inevitably defy the way the database is currently used. These arise from the increasing power of detection of DNA traces, the diversity of demands from police investigators and the growth of the bank itself. Examples of new requirements from the database now include familial searches, low-copy-number analyses and the correct interpretation of mixed samples. This paper aims to develop on the original way set in Québec to address some of these challenges. Nevertheless, analytic and technological advances will inevitably lead to the introduction of new technologies in forensic laboratories, such as single cell sequencing, phenotyping, and proteomics. Furthermore, it will not only request a new holistic/global approach of the forensic molecular biology sciences (through academia and a more investigative role in the laboratory), but also new legal developments. Far from being exhaustive, this paper highlights some of the current use of the database, its potential for the future, and opportunity to expand as a result of recent technological developments in molecular biology, including, but not limited to DNA identification.
La proliferación de discursos en los estudios de género
Rance,Susanna;
Estudios de filosof?-a pr??ctica e historia de las ideas , 2007,
Abstract: as teacher of gender studies, the author observed a gap between the flourishing of sexual and gender diversity, and the persistence in academic courses of binary, biologically-based models. she graphically mapped different approaches including masculinities, the sociology of sex/gender, and internet studies. the proliferation of discourses proposed by foucault and butler has the potential to subvert the hegemony claimed by any current -such as the history of feminism or women in development- as obligatory entry-point to this area of study. from a postmodern perspective, the method opens up the field from women's studies to new themes and subjects of gender studies.
Helping patients attain and maintain asthma control: reviewing the role of the nurse practitioner
Rance KS
Journal of Multidisciplinary Healthcare , 2011, DOI: http://dx.doi.org/10.2147/JMDH.S22966
Abstract: g patients attain and maintain asthma control: reviewing the role of the nurse practitioner Review (3566) Total Article Views Authors: Rance KS Published Date August 2011 Volume 2011:4 Pages 299 - 309 DOI: http://dx.doi.org/10.2147/JMDH.S22966 Karen S Rance Allergy, Asthma and Clinical Immunology Associates, Indianapolis, IN, USA Abstract: Nurse practitioners (NPs) have a unique opportunity as frontline caregivers and patient educators to recognize, assess, and effectively treat the widespread problem of uncontrolled asthma. This review provides a perspective on the role of the NP in implementing the revised National Asthma Education and Prevention Program (NAEPP) Guidelines put forth by the National Heart, Lung, and Blood Institute, thereby helping patients achieve and maintain asthma control. A literature search of PubMed was performed using the terms asthma, nurse practitioner, asthma control, burden, impact, morbidity, mortality, productivity, quality of life, uncontrolled asthma, NAEPP guidelines, assessment, pharmacotherapy, safety. Despite the increased morbidity and mortality and impaired quality of life attributable to uncontrolled asthma, the 2007 NAEPP asthma guidelines are greatly underused. NPs have an opportunity to identify patients at risk and provide enhanced care and education for asthma control. Often, NPs can prescribe medication for and manage these patients, but it is necessary to be able to discern which patients require referral to a specialist.
Helping patients attain and maintain asthma control: reviewing the role of the nurse practitioner
Rance KS
Journal of Multidisciplinary Healthcare , 2011,
Abstract: Karen S RanceAllergy, Asthma and Clinical Immunology Associates, Indianapolis, IN, USAAbstract: Nurse practitioners (NPs) have a unique opportunity as frontline caregivers and patient educators to recognize, assess, and effectively treat the widespread problem of uncontrolled asthma. This review provides a perspective on the role of the NP in implementing the revised National Asthma Education and Prevention Program (NAEPP) Guidelines put forth by the National Heart, Lung, and Blood Institute, thereby helping patients achieve and maintain asthma control. A literature search of PubMed was performed using the terms asthma, nurse practitioner, asthma control, burden, impact, morbidity, mortality, productivity, quality of life, uncontrolled asthma, NAEPP guidelines, assessment, pharmacotherapy, safety. Despite the increased morbidity and mortality and impaired quality of life attributable to uncontrolled asthma, the 2007 NAEPP asthma guidelines are greatly underused. NPs have an opportunity to identify patients at risk and provide enhanced care and education for asthma control. Often, NPs can prescribe medication for and manage these patients, but it is necessary to be able to discern which patients require referral to a specialist.Keywords: asthma control, asthma medications, education, NAEPP guidelines, nurse practitioner, referral
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