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Search Results: 1 - 10 of 466382 matches for " Georgy Armando; García Pe?a "
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Dise o de una formulación de fenilefrina 10 % y tropicamida 1 % colirio: eyedrops Design of a 10 % Phenylephrine and 1 % Tropicamide formula
Georgy Armando Zu?iga Dedorite,Caridad Margarita García Pea,Martha Botet García,Yenilen Troche Concepción
Revista Cubana de Farmacia , 2010,
Abstract: El colirio de fenilefrina 10 % y tropicamida 1 % se emplea en la práctica médica como antihistamínico, analgésico, midriáticos y ciclopléjico. El objetivo del presente trabajo consistió en desarrollar una formulación de fenilefrina 10 % y tropicamida 1 % que cumpliera con las especificaciones de calidad establecidas por el fabricante, que fuera estable física, química y microbiológicamente, para lo cual se realizó un dise o y los estudios de preformulación. Se estudió además, las especificaciones de calidad de la formulación seleccionada, la estabilidad del producto y el tiempo de vigencia de este. Se desarrolló y validó un método analítico para el control de la calidad y el estudio de estabilidad del producto terminado por cromatografía líquida de alta resolución. Se realizaron los resultados analíticos del estudio de estabilidad acelerado y por vida de estante, para lo cual se emplearon 3 lotes del producto a escala piloto. El colirio resultó estable física, química y microbiológicamente envasado en frascos de polietileno de baja densidad, por un tiempo de 12 meses almacenados a temperatura ambiente. The 10 % Phenylephrine and 1 % Tropicamide eyedrops is used in medical practice as antihistaminic, analgesic, mydiatric and cycloplegic. The aim of present paper was to develop a 10% Phenylephrine and 1 % Tropicamide formula fulfilling the quality specifications established by manufacturer physically, chemically and microbiologically stable with the performing of a design and pre-formula studies. Also, we studied the quality specifications of selected formula, the product stability and its expiry time. An analytical method was developed and validated to quality control and stability study of the finished product by high-performance liquid chromatography. Analytical results of accelerated stability study and by shelf life using 3 batches of product at pilot scale. Eyedrops was physically, chemically and microbiologically stable when it was bottling in low density polyethylene flasks during 12 months of storage at room temperature.
Dise?o de una formulación de fenilefrina 10 % y tropicamida 1 % colirio: eyedrops
Zu?iga Dedorite,Georgy Armando; García Pea,Caridad Margarita; Botet García,Martha; Troche Concepción,Yenilen; Montes de Oca Porto,Yanet; Baró Román,Gerardo;
Revista Cubana de Farmacia , 2010,
Abstract: the 10 % phenylephrine and 1 % tropicamide eyedrops is used in medical practice as antihistaminic, analgesic, mydiatric and cycloplegic. the aim of present paper was to develop a 10% phenylephrine and 1 % tropicamide formula fulfilling the quality specifications established by manufacturer physically, chemically and microbiologically stable with the performing of a design and pre-formula studies. also, we studied the quality specifications of selected formula, the product stability and its expiry time. an analytical method was developed and validated to quality control and stability study of the finished product by high-performance liquid chromatography. analytical results of accelerated stability study and by shelf life using 3 batches of product at pilot scale. eyedrops was physically, chemically and microbiologically stable when it was bottling in low density polyethylene flasks during 12 months of storage at room temperature.
Desarrollo y validación de un método analítico para el control de calidad y estabilidad de fenilefrina 10 % colirio y tropicamida 1 % Development and validation of an analytical method for quality control and the stability of the eyedrops 10 % Phenylephrine and the 1 % Tropicamide
Caridad Margarita García Pea,Martha Botet García,Yenilen Troche Concepción,Georgy Zú?iga Dedorite
Revista Cubana de Farmacia , 2011,
Abstract: Se desarrolló y validó un método analítico por cromatografía líquida de alta resolución, aplicable al control de la calidad y el estudio de estabilidad de fenilefrina 10 % más tropicamida 1 %, colirio. Para cuantificar simultáneamente los 2 principios activos en el producto terminado, la separación se realizó a través de una columna cromatográfica Lichrosorb RP-18 (5 μm) (250 x 4 mm), con detección ultravioleta a 253 nm, empleando una fase móvil compuesta por metanol:agua destilada (1:1), con 1,1 g de 1-octanosulfonato de sodio por litro ajustado pH a 3,0 con ácido fosfórico y la cuantificación de este frente a una muestra de referencia con el método del estándar externo. El método analítico desarrollado resultó lineal, preciso, específico y exacto en el rango de concentraciones estudiadas, el cual se estableció para el control de la calidad y el estudio de estabilidad del producto terminado ya que no existían métodos analíticos reportados para estos fines. An analytical high-performance liquid chromatography method was developed and validated applicable to quality control and to stability study of 10 % phenylephrine plus eyedrops 1 % tropicamide. To quantify simultaneously both active principles in the finished product, separation was carried out through a Lichrosorb RP-18 (15 μm) (260 x 4 mm) column chromatography, with ultraviolet detection at 253 nm using the mobile phase composed of methanol: distilled water (1:1), with 1.1 g of sodium 1-octasulfanate by litre and pH fitted to 3.0 with phosphoric acid and the quantification of this front to a reference sample using the external standard method. The analytical method developed was linear, precise, specific and accurate in the rank of study concentrations, established for the quality control and stability study of the finished product since there were not analytical methods designed for these aims.
Desarrollo y validación de un método analítico para el control de calidad y estabilidad de fenilefrina 10 % colirio y tropicamida 1 %
García Pea,Caridad Margarita; Botet García,Martha; Troche Concepción,Yenilen; Zú?iga Dedorite,Georgy; Montes de Oca Porto,Yanet;
Revista Cubana de Farmacia , 2011,
Abstract: an analytical high-performance liquid chromatography method was developed and validated applicable to quality control and to stability study of 10 % phenylephrine plus eyedrops 1 % tropicamide. to quantify simultaneously both active principles in the finished product, separation was carried out through a lichrosorb rp-18 (15 μm) (260 x 4 mm) column chromatography, with ultraviolet detection at 253 nm using the mobile phase composed of methanol: distilled water (1:1), with 1.1 g of sodium 1-octasulfanate by litre and ph fitted to 3.0 with phosphoric acid and the quantification of this front to a reference sample using the external standard method. the analytical method developed was linear, precise, specific and accurate in the rank of study concentrations, established for the quality control and stability study of the finished product since there were not analytical methods designed for these aims.
Riesgo de déficit nutricional antropométrico en el primer trimestre del embarazo
Sánchez Jaeger,Armando; Pea Perdomo,Evelyn; Solano Rodríguez,Liseti; García,Amarilys;
Anales Venezolanos de Nutrición , 2002,
Abstract: to assess nutritional anthropometric risk for low weight during the first trimester of pregnancy, 389 women (11.9±2.7 weeks of gestation), between 13 and 41 years of age, living in poverty in valencia, venezuela 1998 were studied. pre-gestational weight (pgw), actual weight, height, mid arm circumference (mac), and triceps skinfold were determined. arm fat area (afa), arm muscle area (ama) and pre-gestational body mass index (pbmi) were calculated. the cutoff points for mac, afa, and ama were established between the 15th percentile ("below the norm") and the 85th ("above the norm"). women with pbmi<19.8 kg/m2, were considered "low weight". 145 subjects were found at nutritional risk for low weight: the "risk 1" group included women with pbmi and mac below the norm (17.7%), "risk 2" group was characterized by pbmi, mac, and fa below the norm (13.3%), and "risk 3" group by pbmi, mac, fa and ama below the norm (6.1%). from a multivariate cluster analysis three clusters emerged: "cluster a" grouped subjects with "normal" pbmi and mac, "cluster b" grouped pbmi and mac considered "deficient", and cluster c grouped pbmi, mac, and fa "in excess" or above the cutoff points. 90 women at risk were identified by cluster b: 61% of group "risk 1", 60% of group "risk 2", and 71% of group "risk 3". from these results we concluded that: according to pbmi, there is a high nutritional risk and that two or more anthropometric variables are needed to identify potential groups for nutritional interventions.
Infestación y distribución corporal de la nigua Eutrombicula alfreddugesi (Acari: trombiculidae) en el lacertilio de las rocas Sceloporus couchii (Sauria: phrynosomatidae)
Cristina García de la Pea,Armando Contreras Balderas,Gamaliel Casta?eda G.,David Lazcano
Acta zoológica mexicana , 2004,
Abstract: Se estudió el grado de infestación y distribución corporal de la nigua Eutrombicula alfreddugesi en el lacertilio Sceloporus couchii en una localidad del Municipio de Santa Catarina, Nuevo León, México. La mayoría de las lagartijas revisadas portaban estos ácaros, sin embargo, la media del número de ácaros que presentaron los machos fue significativamente mayor que la media de las hembras. No se encontró una relación significativa entre la longitud hocico-cloaca, peso y número total de ácaros en ambos sexos, lo que podría indicar que este parasitismo no influye en la condición física de estos lacertilios. El análisis de la distribución corporal mostró que la región donde se observaron concentrados el mayor número de ácaros fue en las bolsas postfemorales, seguido por la región de la nuca y la región axilar.
Mujer y deporte. hacia la equidad e igualdad
García Avenda?o,Pedro; Flores Esteves,Zhandra; Rodríguez Bermudez,Armando; Brito Navarro,Pedro; Pea Oliveros,Ruben;
Revista Venezolana de Estudios de la Mujer , 2008,
Abstract: our western society runs fast in the production and accumulation of data, information and knowledge which nurture and carry forward the sciences applied to sport, though we find pretty evidences to sustain yet the lack of information and wrong orientation about woman?s potential and role in physical and sporting activities. to attain equity, justice and equality is necessary to study the present situation, with plenty of beliefs and false myths, in order to dismantle them through reflection, argumentation and true knowledge that allow the pursuit of enjoying the pleasure of the right to physical activity and sport for women.
Ciclos de actividad diaria y estacional de un gremio de saurios en las dunas de arena de Viesca, Coahuila, México
García-De la Pea, Cristina;Gadsden, Héctor;Contreras-Balderas, Armando J.;Casta?eda, Gamaliel;
Revista mexicana de biodiversidad , 2007,
Abstract: in 2002, daily and seasonal activity patterns of the lizards uta stejnegeri, uma exsul, and aspidoscelis marmorata were evaluated in a dune habitat in the southwestern portion of coahuila, mexico. methods included surveying a 500 m transect once per hour between 0700 and 1900 for 7 days each season during the spring, summer and fall. the number of active lizards, air and substrate temperatures, and relative humidity were recorded. a standardized levins index and pianka’s method were used to measure temporal niche breadth and overlap, respectively. in each of the 3 seasons, u. stejnegeri was active earlier than u. exsul, and u. exsul was active before a. marmorata. the 3 species showed a bimodal activity pattern during spring and summer, and unimodal in fall. aspidoscelis marmorata showed the smallest niche breadth in the 3 seasons. for each species, preferred body temperature and environmental temperature seem to dictate activity patterns of this lizard guild at viesca.
Ciclos de actividad diaria y estacional de un gremio de saurios en las dunas de arena de Viesca, Coahuila, México Daily and seasonal activity patterns of a lizard guild in the sand dunes of Viesca, Coahuila, Mexico
Cristina García-De la Pea,Héctor Gadsden,Armando J. Contreras-Balderas,Gamaliel Casta?eda
Revista mexicana de biodiversidad , 2007,
Abstract: En el 2002 se evaluaron los ciclos de actividad diaria y estacional de los saurios Uta stejnegeri, Uma exsul y Aspidoscelis marmorata en un hábitat de dunas al suroeste de Coahuila, México. Se recorrió un transecto de 500 m, cada hora (de 0700 a 1900 h) durante 7 días, en primavera, verano y oto o. Se registró el número de individuos activos por especie, la temperatura del aire y del sustrato, y la humedad relativa. La amplitud de nicho temporal se calculó mediante el índice estandarizado de Levins, y el traslape de nicho mediante el método de Pianka. En las 3 estaciones del a o U. stejnegeri inició su actividad más temprano que U. exsul, y ésta, a su vez, se registró antes que A. marmorata. Las 3 especies presentaron un ciclo de actividad bimodal durante primavera y verano, y unimodal en oto o. Aspidoscelis marmorata presentó la menor amplitud de nicho temporal durante las 3 estaciones. La temperatura corporal de cada especie y la temperatura ambiental parecen determinar los patrones de actividad de este gremio de saurios en Viesca. In 2002, daily and seasonal activity patterns of the lizards Uta stejnegeri, Uma exsul, and Aspidoscelis marmorata were evaluated in a dune habitat in the southwestern portion of Coahuila, Mexico. Methods included surveying a 500 m transect once per hour between 0700 and 1900 for 7 days each season during the spring, summer and fall. The number of active lizards, air and substrate temperatures, and relative humidity were recorded. A standardized Levins Index and Pianka’s method were used to measure temporal niche breadth and overlap, respectively. In each of the 3 seasons, U. stejnegeri was active earlier than U. exsul, and U. exsul was active before A. marmorata. The 3 species showed a bimodal activity pattern during spring and summer, and unimodal in fall. Aspidoscelis marmorata showed the smallest niche breadth in the 3 seasons. For each species, preferred body temperature and environmental temperature seem to dictate activity patterns of this lizard guild at Viesca.
Tail loss incidence in the Chihuahuan fringe toed-lizard Uma paraphygas (Squamata: Phrynosomatidae) Incidencia de autotomía caudal en la lagartija de arena de Chihuahua Uma paraphygas (Sauria: Phrynosomatidae)
Gamaliel Casta?eda,Cristina García-De la Pea,Héctor Gadsden,Armando J. Contreras-Balderas
Revista mexicana de biodiversidad , 2011,
Abstract: We analyzed lizard population density and tail loss frequency in 2 populations of Uma paraphygas to determine if the proportion of lizards with tail loss was different between populations, sexes, and age classes. Also, we estimated unbroken and regenerated tail growth rates for adult males and females, and juveniles. Data were collected between fall 1997 and summer 1999. Tail loss incidence was relatively low overall, but was significantly higher at the site (Dune 1) with lower vegetation cover. Adult lizards showed a higher tail loss frequency than juveniles at the site with higher vegetation density (Dune 2); there was no difference between adult males and females in both dunes. Observations on 33 lizards with bite marks suggest that intraspecific encounters are not a direct cause of caudal autotomy in this species. The caudal growth rates of lizards were similar for unbroken and regenerated tails between sexes and among age classes. Analizamos la densidad poblacional y la frecuencia de autotomía caudal en 2 poblaciones de Uma paraphygas para determinar si la proporción de lagartijas con cola regenerada fue diferente entre poblaciones, sexos y clases de edad. También estimamos las tasas de crecimiento de la cola en regeneración y la original para machos y hembras adultas y juveniles. Los datos se tomaron estacionalmente desde el oto o de 1997 hasta el verano de 1999. La incidencia de pérdida de cola fue relativamente baja en proporción con la densidad poblacional y fue mayor en la población con menor cobertura vegetal (Duna 1). Las lagartijas adultas presentaron mayor autotomía caudal sólo en la población con mayor vegetación (Duna 2); sin embargo, no hubo diferencia entre machos y hembras adultos en ambas poblaciones. Observaciones en 33 lagartijas con marcas de mordidas sugieren que los encuentros intraespecíficos no causan directamente la autotomía caudal en esta especie. Las tasas de crecimiento de la cola original y regenerada de las lagartijas fueron similares entre sexos y entre clases de edad.
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