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Search Results: 1 - 10 of 462000 matches for " Gbolasere A. A. Akanmu "
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Introducing Weighted Nodes to Evaluate the Cloud Computing Topology  [PDF]
Gbolasere A. A. Akanmu, Frank Z. Wang, Huankai Chen
Journal of Software Engineering and Applications (JSEA) , 2012, DOI: 10.4236/jsea.2012.531111
Abstract: Typical data centers house several powerful ICT (Information and Communication Technology) equipment such as servers, storage devices and network equipment that are high-energy consuming. The nature of these high-energy consuming equipment is mostly accountable for the very large quantities of emissions which are harmful and unfriendly to the environment. The costs associated with energy consumption in data centers increases as the need for more computational resources increases, so also the appalling effect of CO2 (Carbon IV Oxide) emissions on the environment from the constituent ICT facilities-Servers, Cooling systems, Telecommunication systems, Printers, Local Area Network etc. Energy related costs would traditionally account for about 42% (forty-two per cent) of the total costs of running a typical data center. There is a need to have a good balance between optimization of energy budgets in any data center and fulfillment of the Service Level Agreements (SLAs), as this ensures continuity/profitability of business and customer’s satisfaction. A greener computing from what used to be would not only save/sustain the environment but would also optimize energy and by implication saves costs. This paper addresses the challenges of sustainable (or green computing) in the cloud and proffer appropriate, plausible and possible solutions. The idle and uptime of a node and the traffic on its links (edges) has been a concern for the cloud operators because as the strength and weights of the links to the nodes (data centres) increases more energy are also being consumed by and large. It is hereby proposed that the knowledge of centrality can achieve the aim of energy sustainability and efficiency therefore enabling efficient allocation of energy resources to the right path. Mixed-Mean centrality as a new measure of the importance of a node in a graph is introduced, based on the generalized degree centrality. The mixed-mean centrality reflects not only the strengths (weights) and numbers of edges for degree centrality but it combines these features by also applying the closeness centrality measures while it goes further to include the weights of the nodes in the consideration for centrality measures. We illustrate the benefits of this new measure by applying it to cloud computing, which is typically a complex system. Network structure analysis is important in characterizing such complex systems.
Prevalence of activated protein C resistance (Factor V Leiden) in Lagos, Nigeria
TA Adeyemo, A Adediran, AA Akinbami, AS Akanmu
Nigerian Journal of Clinical Practice , 2012,
Abstract: Objectives: Hereditary resistance to activated Protein C (Factor V Leiden) is the commonest genetic defect known to confer a predisposition to thrombosis. This study aims to determine the prevalence of activated protein C resistance (APCr) in Lagos, and to determine if any association exists between APCr and ABO, Rhesus blood types, and hemoglobin phenotypes. Materials and Methods: A functional APCr test was conducted on healthy adult volunteers to get a Factor-V-related activated protein C ratio (APC-V ratio). APCr due to Factor V mutation was indicated when the APC-V ratio is below a cut-off value that was determined by calibration. Subjects’ hemoglobin, red cell ABO, and Rhesus phenotypes were determined by standard methods. Results: Six (2%) of 297 participants with normal baseline coagulation screening tests had functional resistance to activated protein C (APC-V ratio < 2). None of the six subjects with APCr had history of venous thromboembolism. One of the six subjects was a female but the male sex did not demonstrate a risk of inheritance of APCr (P = 0.39). Four (67%) of the six subjects with APCr were non-O blood group. Whereas only two (0.9%) of 226 non-A subjects (blood groups 0 and B) had APCr, 4 (6%) of 71 subjects with A gene (blood groups A and AB) had APCr. The inheritance of A gene appears to constitute a risk to inheritance of APCr (P = 0.03). No association was demonstrable between APCr and hemoglobin phenotypes. Conclusion: Only 2% of the studied population had resistance to APC. The inheritance of blood group A may be a predisposition to APCr.
Homocysteine Levels in Nigerian Women with Pre-eclampsis/Eclampsia
VO Osunkalu, AS Akanmu, A Adediran, O Abudu
Sierra Leone Journal of Biomedical Research , 2009,
Abstract: Hyperhomocysteinaemia has been linked in various studies worldwide to the occurrence of cardiovascular disorders and endothelial cell injury. In Nigeria with one of the highest maternal/neonatal mortality and morbidity, it is significant to explore means of predicting pregnancy-induced hypertension. This study was carried out at the Lagos University Teaching Hospital which is a major referral center in the South-western part of Nigeria. It was set to determine the mean plasma homocysteine levels and corpuscular haemoglobin in pre-eclamptic/eclamptic Nigerian women. A total of 150 subjects consisting of 100 primigravidae and 25 diagnosed cases of pre-eclampsia/eclampsia and 25 non-pregnant females were enrolled in the study. 60 primigravidae were lost to follow up or had incomplete data. The mean value of homocysteine in the control group, and eclamptic group was 7.5±3.4 μmol/L and 16.1±6.5 μmol/L respectively. There is positive and significant correlation between plasma homocysteine in the eclamptic group and the mean MCV (r=0.97, p=0.01), and between plasma homocysteine, systolic and diastolic blood pressure of the eclamptic group (r=0.944, p=0.0001; r=0.98, p=0.0001). The study further supports earlier findings of increased homocysteine levels in the occurrence of pre-eclampsia/eclampsia.
TOXICITY POTENTIALS OF CASSIA FISTULA FRUITS AS LAXATIVE WITH REFERENCE TO SENNA
M. A. AKANMU,E. O. IWALEWA
African Journal of Biomedical Research , 2004,
Abstract: The aqueous extract of the pods of Cassia fistula Linn (Leguminosae - Caesalpinoideae), cultivated in Ile-Ife, Nigeria were investigated for pharmacological and toxicological properties. The in-vitro effect of Cassia fistula infusion on isolated guinea-pig ileum was examined. The acute and sub-chronic toxicity of the infusion of C. fistula and Cassia acutifolia Del. Pod-(Senokot tablet) as the reference drug were also determined. The results obtained for C .fistula infusion when compared with senokot tablet showed that the infusion of Cassia fistula pods possessed very low levels of toxicity, having the LD50 of 6600mg/kg and also without any pathological effects on the organs examined microscopically. It is therefore concluded from the study that C. fistula pod infusion could be safely utilized as laxative drugs and as a substitute for the official Senna
An RTLS-Based Approach to Cyber-Physical Systems Integration in Design and Construction
Abiola A. Akanmu,Chimay J. Anumba,John I. Messner
International Journal of Distributed Sensor Networks , 2012, DOI: 10.1155/2012/596845
Abstract:
An RTLS-Based Approach to Cyber-Physical Systems Integration in Design and Construction
Abiola A. Akanmu,Chimay J. Anumba,John I. Messner
International Journal of Distributed Sensor Networks , 2012, DOI: 10.1155/2012/596845
Abstract: There have been several approaches to integrating physical construction components and their virtual models using RFID tags. These enable the movement of components to be tracked on the construction site. However, there is inadequate support for bidirectional coordination between these components and their virtual representations. Also, these approaches often involve manual input of status information into the tags and do not support tracking the permanent installed position of tagged components for consistency maintenance between the as-built and the as-planned models. As such, there are difficulties with ensuring accurate and timely updating of building information models and tag information during the construction process. A major bottleneck in achieving this integration is the choice of appropriate mechanisms for binding physical components with their virtual representations. This paper presents an approach to facilitating bidirectional coordination between physical construction components and their virtual models. Specialized real-time location sensing (RTLS) tags were used for tracking the position and status of physical construction components. This approach showed significant opportunities for enhancing real-time construction consistency checking, which will aid proactive decision making and control. The paper also discusses experiments undertaken to demonstrate the proposed RTLS-based system and highlights the merits and demerits of adopting the proposed approach on a full-scale project. 1. Introduction Being able to accurately and efficiently monitor construction progress in real time enables project managers to detect schedule delays early and make corrective decisions [1]. Over the years, virtual models have proved their worth in construction progress monitoring as a means of visualizing the construction process. Virtual models also contain virtual representations of building components which can be linked to their physical representations on the construction site. As a facility moves through the life cycle from planning to design to construction and to facility management, some information can be embedded in the virtual building components and this provides another integrated database of relevant information that can be used by the project team during the construction and postconstruction phases of the constructed facility. This potential of virtual models is evident in the research by Anumba et al. [2], S?rensen et al. [3], and Motamedi and Hammad [4] which identified that integrating virtual models and the physical construction can
Prevalence and type of monoclonal gammopathy of undetermined significance in an apparently healthy Nigerian population: a cross sectional study
A Lawretta Onwah, Titilope A Adeyemo, Adewumi Adediran, Sarah O Ajibola, Alani S Akanmu
BMC Blood Disorders , 2012, DOI: 10.1186/1471-2326-12-7
Abstract: A cross sectional survey was carried on apparently healthy Nigerians selected by multistage sampling technique from the cosmopolitan city of Lagos, Nigeria. Subjects enrolled into the study had 2-step screening for the presence, type and concentration of monoclonal band. Agarose-gel electrophoresis was performed on all serum samples, and any serum sample with a discrete band of monoclonal protein or thought to have a localized band was subjected to Immunofixation. Subjects were also evaluated for Bence jones proteinuria, haematological and biochemical parameters.Four hundred and ten subjects with a mean age of 45.68?±?10.3 years, a median of 45.00 years and a range of 20 to 80 years were enrolled into the study. MGUS was identified in only one (0.24 percent) of the 410 study subject. This subject was demonstrated to have a double monoclonal gammopathy; IgGλ at 16.9 g/L and IgAκ at 8.5 g/L. None of them including the sole subject with MGUS had a monoclonal urinary light chain.Among residents of Lagos, Nigeria, MGUS was found in only 0.24% percent of apparently normal persons with a median age of 45 years. This suggests that MGUS which represents the earliest stage of monoclonal plasma/lymphoid cell proliferation is not a common finding in the relatively young population of Nigeria. Future epidemiologic studies dealing with plasma cell disorders in older people are required to carefully examine the relationship between environmental factors and prevalence of MGUS and its ultimate progression to MM.
Relationship Between Plasma Homocysteine and Vitamin B12 Levels in Clinically Diagnosed Cases of Cardiovascular Accident in Lagos, Nigeria
O Osunkalu, S Akanmu, O Awodele, A Ayoola, A Adewumi, N Agada, R Akinde
Sierra Leone Journal of Biomedical Research , 2009,
Abstract: Vitamin B12 deficiency interferes with the normal pathway for homocysteine metabolism, even in the presence of adequate serum folate and pyridoxine. Homocysteinaemia, is an elevated level of homocysteine in plasma which has been established as a risk factor for the development of cardiovascular disorders. However, there has been conflicting report from various research works on the role of Vitamin B12 in the occurrence of major cardiovascular disorders. The study was set to determine the mean values of homocysteine, and correlate same with mean plasma levels of vitamin B12 in the subjects, and to estimate the prevalence of anaemia in the stroke patients, using Haemoglobin concentration (Hb) and mean corpuscular volume (MCV) as indices. One hundred (100) participants were recruited, comprising 40 clinically diagnosed stroke patients (hemorrhagic or thrombo-embolic), and 60 normal adults as control group. Plasma homocysteine levels were measured by HPLC and plasma vitamin B12 levels by Chemiluminescent Microparticle Immuno-assay method. Anticoagulated whole blood samples were evaluated for Hb, and MCV using automated Advia-60. Mean value of plasma homocysteine for the stroke patients (17.7±4.4umol/l) was significantly higher than values obtained in the control group at 9.5±2.4umol/l (p<0.001). Mean plasma vitamin B12 levels for both the stroke patients and controls were 249±14.5 pmol/l and 203.6±20.5 pmol/l respectively (p=0.029). The MCV for the study group (85fl) were significantly higher than those of the control group (82fl), p=0.040. However, the study showed no correlation between rising plasma homocysteine in stroke patient and vitamin B12 deficiency.
Comparative Study of Complexities of Breadth-First Search and Depth-First Search Algorithms using Software Complexity Measures
Akanmu T. A.,Olabiyisi S. O.,Omidiora E. O.,Oyeleye C. A.
Lecture Notes in Engineering and Computer Science , 2010,
Abstract:
Breast Cancer among Urban Nigerian Women: Appraising Presentation and the Quality of Care
Nasiru Akanmu Ibrahim, Abiodun O Popoola, Mobolaji A Oludara, Foluso O Omodele, Idowu Olesegun Fadeyibi
Macedonian Journal of Medical Sciences , 2011, DOI: 10.3889/MJMS.1857-5773.2011.0187
Abstract: Introduction: Late presentation is the hallmark of breast cancer among Nigerians. Awareness of the disease is low and care of this condition has not received adequate attention from Government. Health education to improve awareness was intensified in the last 2 decades. This study aims to assess the current state of care and presentation of breast cancer in Lagos, Nigeria. Patients and Methods: A prospective study of 350 breast cancer patients seen over a period of four years at a General Surgical unit out-patient clinic of LASUTH was carried out. Data on patient characteristics, presentation, diagnosis and treatment were obtained and analyzed. Results: Average duration of symptoms was 46.48 weeks. One fifth presented within 3 months while 17% presented after 1 year. Lumps were self-detected in 96% and 287 (82%) presented with advanced disease (stages III & IV). Two hundred and thirty seven patients (67%) received treatment and 175 (74%) among them had mastectomy. None had breast conservation surgery. One hundred and fourteen patients (48%) absconded and did complete treatment. Conclusion: The trend of late presentation has not changed with current efforts to improve breast cancer awareness. Quality of care for our breast cancer patients is not satisfactory and needs improvement.
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