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Search Results: 1 - 10 of 551 matches for " Garrett Fitzmaurice "
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Association of Regional Variation in Primary Care Physicians’ Colorectal Cancer Screening Recommendations with Individual Use of Colorectal Cancer Screening
Jennifer S. Haas, MD, MSPH,Garrett Fitzmaurice, ScD,Phyllis Brawarsky, MPH,Su-Ying Liang, PhD
Preventing Chronic Disease , 2007,
Abstract: IntroductionStudies show that the recommendations of a primary care physician for colorectal cancer screening may be one important influence on an individual’s use of screening. However, another possible influence, the effect of regional differences in physicians’ beliefs and recommendations on screening use, has not been assessed.MethodsWe linked data from the National Health Interview Survey on the use of colorectal cancer screening by respondents aged 50 years or older, by hospital-referral region, with data from the Survey of Colorectal Cancer Screening Practices on the colorectal cancer screening recommendations of primary care physicians, by region. Our principal independent variables were the proportion of physicians in a region who recommended screening at age 50 and continuing screening at the recommended frequency.Results On average, 53.3% of physicians in a region correctly recommended initiating colorectal cancer screening, and 64.8% advised screening at the recommended frequency. Of adults who lived in regions where less than 30% of physicians correctly recommended initiating screening, 47.3% had been screened, in contrast to 54.8% in areas where 70% or more of physicians made correct recommendations. Seventy-one percent of respondents living in regions where less than 30% of physicians advised screening at the recommended frequency were current on screening, in contrast to 79.9% of respondents living in regions where 70% or more of physicians made this recommendation. These differences were statistically significant after adjustment for individual characteristics.ConclusionStrategies to improve colorectal cancer screening recommendations of primary care physicians may improve the use of screening for millions of Americans.
Simple Methods of Determining Confidence Intervals for Functions of Estimates in Published Results
Garrett Fitzmaurice, Stuart Lipsitz, Sundar Natarajan, Atul Gawande, Debajyoti Sinha, Caprice Greenberg, Edward Giovannucci
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0098498
Abstract: Often, the reader of a published paper is interested in a comparison of parameters that has not been presented. It is not possible to make inferences beyond point estimation since the standard error for the contrast of the estimated parameters depends upon the (unreported) correlation. This study explores approaches to obtain valid confidence intervals when the correlation is unknown. We illustrate three proposed approaches using data from the National Health Interview Survey. The three approaches include the Bonferroni method and the standard confidence interval assuming (most conservative) or (when the correlation is known to be non-negative). The Bonferroni approach is found to be the most conservative. For the difference in two estimated parameter, the standard confidence interval assuming yields a 95% confidence interval that is approximately 12.5% narrower than the Bonferroni confidence interval; when the correlation is known to be positive, the standard 95% confidence interval assuming is approximately 38% narrower than the Bonferroni. In summary, this article demonstrates simple methods to determine confidence intervals for unreported comparisons. We suggest use of the standard confidence interval assuming if no information is available or if the correlation is known to be non-negative.
The Effect of NeuroGen® Nerve Support Supplement on Pillar Pain after Endoscopic Carpal Tunnel Release  [PDF]
Michael J. Fitzmaurice
Modern Plastic Surgery (MPS) , 2014, DOI: 10.4236/mps.2014.41002

61 patients with clinically diagnosed and electromyographically confirmed carpal tunnel syndrome were enrolled in a prospective study to evaluate the effectiveness of a nerve supplement on pillar pain after carpal tunnel surgery. All of the patients underwent endoscopic carpal tunnel release. 15 of the patients also took the nerve support supplement NeuroGen? as part of their perioperative treatment. The supplement group demonstrated a significantly lower amount of pillar pain (VAS) at initial follow up compared to the control group (1.13 and 4.05 respectively). 46% (7/15) of the supplement group were completely free of pillar pain compared to only 9% (4/46) of the control group at the first follow up. 53% (8/15) of the NeuroGen? group did not require any pain medications compared to 35% (16/46) of the control group. The Nerve supplement NeuroGen? significantly reduces pain after carpal tunnel surgery.

Nanofat and Platelet Rich Plasma to Enhance Recovery and Minimize Risk of Recurrence after Endoscopic Carpal Tunnel Release  [PDF]
Michael J. Fitzmaurice
Modern Plastic Surgery (MPS) , 2019, DOI: 10.4236/mps.2019.91002
Abstract: Carpal tunnel release is one of the most common and surgery procedures performed. Complications and recurrence of the condition can occur up to 20% of cases. We describe a technique of utilizing the nanofat and platelet rich plasma to successfully enhance healing and minimize risk of recurrence after endoscopic carpal tunnel release. This patient had exceptionally fast recovery, resuming work in one day and excellent grip strength and a full functioning level at his two-week follow-up. After one year he continues to demonstrate a complete resolution of symptoms and full function without any evidence of recurrence or complications.
A generalized linear mixed model for longitudinal binary data with a marginal logit link function
Michael Parzen,Souparno Ghosh,Stuart Lipsitz,Debajyoti Sinha,Garrett M. Fitzmaurice,Bani K. Mallick,Joseph G. Ibrahim
Statistics , 2011, DOI: 10.1214/10-AOAS390
Abstract: Longitudinal studies of a binary outcome are common in the health, social, and behavioral sciences. In general, a feature of random effects logistic regression models for longitudinal binary data is that the marginal functional form, when integrated over the distribution of the random effects, is no longer of logistic form. Recently, Wang and Louis [Biometrika 90 (2003) 765--775] proposed a random intercept model in the clustered binary data setting where the marginal model has a logistic form. An acknowledged limitation of their model is that it allows only a single random effect that varies from cluster to cluster. In this paper we propose a modification of their model to handle longitudinal data, allowing separate, but correlated, random intercepts at each measurement occasion. The proposed model allows for a flexible correlation structure among the random intercepts, where the correlations can be interpreted in terms of Kendall's $\tau$. For example, the marginal correlations among the repeated binary outcomes can decline with increasing time separation, while the model retains the property of having matching conditional and marginal logit link functions. Finally, the proposed method is used to analyze data from a longitudinal study designed to monitor cardiac abnormalities in children born to HIV-infected women.
Acute low back pain is marked by variability: An internet-based pilot study
Pradeep Suri, James Rainville, Garrett M Fitzmaurice, Jeffrey N Katz, Robert N Jamison, Julia Martha, Carol Hartigan, Janet Limke, Cristin Jouve, David J Hunter
BMC Musculoskeletal Disorders , 2011, DOI: 10.1186/1471-2474-12-220
Abstract: We conducted a cohort study of acute LBP patients utilizing frequent serial assessments and Internet-based data collection. Adults with acute LBP (lasting ≤3 months) completed questionnaires at the time of seeking care, and at both 3-day and 1-week intervals, for 6 weeks. Back pain was measured using a numerical pain rating scale (NPRS), and disability was measured using the Oswestry Disability Index (ODI). A pain flare was defined as 'a period of increased pain lasting at least 2 hours, when your pain intensity is distinctly worse than it has been recently'. We used mixed-effects linear regression to model longitudinal changes in pain intensity, and multivariate linear regression to model associations between flare frequency and disability outcomes.42 of 47 participants (89%) reported pain flares, and the average number of discrete flare periods per patient was 3.5 over 6 weeks of follow-up. More than half of flares were less than 4 hours in duration, and about 75% of flares were less than one day in duration. A model with a quadratic trend for time best characterized improvements in pain. Pain decreased rapidly during the first 14 days after seeking care, and leveled off after about 28 days. Patients who reported a pain flare experienced an almost 3-point greater current NPRS than those not reporting a flare (mean difference [SD] 2.70 [0.11]; p < 0.0001). Higher flare frequency was independently associated with a higher final ODI score (? [SE} 0.28 (0.08); p = 0.002).Acute LBP is characterized by variability. Patients with acute LBP report multiple distinct flares of pain, which correspond to discrete increases in pain intensity. A higher flare frequency is associated with worse disability outcomes.The terms 'acute' and 'chronic' are commonly used in both research and clinical practice to characterize low back pain (LBP) and its prognosis. These terms as used in back pain research have been criticized, however, on the grounds that they overemphasize symptom durati
The Downlink Adjacent Interference for Low Earth Orbiting (LEO) Search and Rescue Satellites  [PDF]
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2010, DOI: 10.4236/ijcns.2010.32016
Abstract: NOAA (National Oceanic and Atmospheric Administration) - LEO environmental satellites provide continuous coverage of Earth, supplying high-resolution global meteorological, oceanic and space observation data. In addition, these satellites are part of the international COSPAS – SARSAT program, which aides search and rescue teams worldwide. The USA segment, referred to as SARSAT (Search and Rescue Satellite Aided Tracking) system, is designed to provide distress alert and location data to assist on search and rescue operations. SARSAT locates distress beacons (406MHz) activated at distress locations. The system calculates a location of the distress event using Doppler processing techniques. Processed data is continuously retransmitted through the SARSAT downlink to Local User Terminals (LUT) when satellites are in view. The downlink adjacent interference is expected when two satellites operate in close proximity and share the same frequency. The downlinks of all SARSAT LEO satellites use the same 1544.5 MHz frequency. In cases where the satellites are within the main lobe of the local user terminal antenna, transmissions from adjacent satellites act as interference to one-another, effectively decreasing the signal-to-noise ratio of the desired downlink. This can result in missed distress beacon bursts or no stored solutions received at the LUT, consequently no data is provided about a distress location. Analysis on interference prediction, impacts on system operation and recommendations for mitigating interference periods where the duration may be significant, are presented in this paper.
Generalized Legendre-Stirling Numbers  [PDF]
K. C. Garrett, Kendra Killpatrick
Open Journal of Discrete Mathematics (OJDM) , 2014, DOI: 10.4236/ojdm.2014.44014
Abstract: The Legendre-Stirling numbers were discovered by Everitt, Littlejohn and Wellman in 2002 in a study of the spectral theory of powers of the classical second-order Legendre differential operator. In 2008, Andrews and Littlejohn gave a combinatorial interpretation of these numbers in terms of set partitions. In 2012, Mongelli noticed that both the Jacobi-Stirling and the Legendre-Stirling numbers are in fact specializations of certain elementary and complete symmetric functions and used this observation to give a combinatorial interpretation for the generalized Legendre-Stirling numbers. In this paper we provide a second combinatorial interpretation for the generalized Legendre-Stirling numbers which more directly generalizes the definition of Andrews and Littlejohn and give a combinatorial bijection between our interpretation and the Mongelli interpretation. We then utilize our interpretation to prove a number of new identities for the generalized Legendre-Stirling numbers.
A tracheal septum during routine pre-operative work-up
Fitzmaurice Gerard,Nasir Abdul,MacGowan Simon
Annals of Cardiac Anaesthesia , 2010,
Six Imprisoned Health-Care Workers in Libya Are Pawns in a Far Larger Strategic Game
Laurie Garrett
PLOS Medicine , 2006, DOI: 10.1371/journal.pmed.0030514
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