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Search Results: 1 - 10 of 56349 matches for " Gao Xin-ying "
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Kinetics of catalytically activated aggregation-fragmentation process

Gao Yan,Wang Hai-Feng,Lin Zhen-Quan,Xue Xin-Ying,

中国物理 B , 2011,
Performance of MLC/PDL with Convolutional Codes as Component Codes under a New Distance Metric

Zhang Yu-ling,Yuan Dong-feng,Gao Xin-ying,

电子与信息学报 , 2005,
Abstract: A new distance metric for MLC/PDL (MultiLevel Coding/ Parallel Decoding of Levels) with MQAM constellation is proved to be applicable when punctured convolutional code is used as component code over Rayleigh fading channel. The efficiency has been demonstrated by detailed simulation results. The performance comparison between punctured convolutional code and block code under the same condition is also given.
Is High Resolution Melting Analysis (HRMA) Accurate for Detection of Human Disease-Associated Mutations? A Meta Analysis
Bing-Sheng Li, Xin-Ying Wang, Feng-Li Ma, Bo Jiang, Xiao-Xiao Song, An-Gao Xu
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0028078
Abstract: Background High Resolution Melting Analysis (HRMA) is becoming the preferred method for mutation detection. However, its accuracy in the individual clinical diagnostic setting is variable. To assess the diagnostic accuracy of HRMA for human mutations in comparison to DNA sequencing in different routine clinical settings, we have conducted a meta-analysis of published reports. Methodology/Principal Findings Out of 195 publications obtained from the initial search criteria, thirty-four studies assessing the accuracy of HRMA were included in the meta-analysis. We found that HRMA was a highly sensitive test for detecting disease-associated mutations in humans. Overall, the summary sensitivity was 97.5% (95% confidence interval (CI): 96.8–98.5; I2 = 27.0%). Subgroup analysis showed even higher sensitivity for non-HR-1 instruments (sensitivity 98.7% (95%CI: 97.7–99.3; I2 = 0.0%)) and an eligible sample size subgroup (sensitivity 99.3% (95%CI: 98.1–99.8; I2 = 0.0%)). HRMA specificity showed considerable heterogeneity between studies. Sensitivity of the techniques was influenced by sample size and instrument type but by not sample source or dye type. Conclusions/Significance These findings show that HRMA is a highly sensitive, simple and low-cost test to detect human disease-associated mutations, especially for samples with mutations of low incidence. The burden on DNA sequencing could be significantly reduced by the implementation of HRMA, but it should be recognized that its sensitivity varies according to the number of samples with/without mutations, and positive results require DNA sequencing for confirmation.
Colorectal cancer in Guangdong Province of China: A demographic and anatomic survey
An-Gao Xu, Zhi-Jin Yu, Bo Jiang, Xin-Ying Wang, Xu-Hui Zhong, Ji-Hong Liu, Qiu-Yun Lou, Ai-Hua Gan
World Journal of Gastroenterology , 2010,
Abstract: AIM: To determine the basic demographic features of colorectal cancer (CRC) in five hospitals located in four different areas of Guangdong Province, China.METHODS: A review of patient records from 1986 to 2006 from five hospitals was conducted. Patient data was obtained, including age, gender, location of lesions, staging and histological type of CRC. The Chi-square test was used to assess differences in rates and a significance level of 0.05 was used. Univariate comparisons were made via Fisher’s exact tests.RESULTS: Analysis was carried out on 8172 CRC patents, 6.1% (499/8172) of the patients were aged ≤ 30 years. The peak incidence was between the ages 61-70 years (27.8%). The mean age at CRC diagnosis increased from 52 years (1986-1988) to 60 years (2004-2006) and the proportion of young CRC patients decreased from 8.0% to 5.9% over the same period. Of 8172 lesions, 4434 (54.3%) were located in rectum and 3738 (45.7%) in colon. The incidence of rectal cancer decreased significantly from 59.4% (1989-1991) to 51.8% (2004-2006) and right sided colon cancer increased from 40.6% to 48.2%. The mean age, anatomic distribution, histological type and differentiation degree were significantly different among the four geographical areas (P < 0.05).CONCLUSION: The hospitalization rate for CRC has increased in Guangdong in recent years. The characteristics of CRC from the five hospitals located in the four different areas of Guangdong Province are also different. Further studies are needed to assess more recent trend in the incidence and prevalence of CRC as well as the respective roles of genetic and environmental factors in CRC.
Realization of a Video Convertion Module Based on Batch Programs

ZHAO Xin-Ying,

计算机系统应用 , 2011,
Abstract: This paper realizes a module which can convert almost all formats of current video files to files of flv format which can be played on the Web pages timingly, automaticly and batchingly. Firstly, it introduces current main video formats, along with Mencoder and Ffmpeg components. Secondly, it introduces the workflow design of this module. Finally, the paper introduces function realization of its submodules, and matters we should pay attention to in practical applications.
Yan He,Liang-Yan Cui,Xin-Ying Zhang
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811032272
Abstract: In the crystal structure of the title compound, C8H6N2O3, the molecules are linked by a pairs of intermolecular N—H...O hydrogen bonds, forming inversion dimers. The aldehyde group is in the same plane as the pyrimidine ring [with a maximum deviation of 0.083 (2) for the O atom), and the linear propargyl group [C—C—C = 178.99 (19)°] makes a dihedral angle of 74.36 (13)° with the ring.
Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone
Xin-ying Feng,Wen-wei Li
Zhong Xi Yi Jie He Xue Bao , 2012,
Abstract: OBJECTIVE: To observe the protective effects of echinacoside on rotenone-induced damages in rats.METHODS: Healthy male Sprague-Dawley rats, weighing from 200 to 220 g, were randomly divided into five groups with 20 rats in each group: control group, rotenone group and echinacoside groups of low, medium and high doses (20, 40 and 80 mg/(kg·d)). Rats in the rotenone group were injected intraperitoneally for four weeks with rotenone (2.75 mg/(kg·d)), dissolved into dimethyl sulfoxide; rats in the control group were injected intraperitoneally with dimethyl sulfoxide daily, and rats in the echinacoside groups received daily intraperitoneal injection of rotenone along with echinacoside gastric perfusion for four weeks. Modified neurological severity score was used to evaluate neurobehavior of the animals; dopaminergic neurons in substantia nigra were observed by immunochemical method and dopamine concentration in striatum was determined by a fluorescence spectrophotometer. Biomarkers of liver and kidney damage were also measured.RESULTS: In the rotenone group, the rats suffered from severe neurological disability (P<0.01), and the number of dopaminergic neurons in substantia nigra and dopamine concentration in striatum were decreased (P<0.05) compared with the normal control group; levels of the biomarkers for evaluating liver and kidney damage were increased (P<0.05). In the echinacoside groups, the neurological disability and the loss of dopaminergic neurons in substantia nigra were suppressed and dopamine concentrations in striatum were increased (P<0.05), but the liver and kidney damage was not improved (P>0.05).CONCLUSION: Rotenone causes severe damages to dopaminergic neurons, liver and kidney in rats and echinacoside selectively reverses dopaminergic neuronal injury.
Effects of Different Self Etching Adhesives and Resins on Microleakage of Class V Restorations.

WANG Xin-ying
, WAN Na, YAN Lei, YIN Yan-jiao, CAO Rong-rong, XIONG Meng-lin, GAO Wen-hui, WU Pei-ling

- , 2017, DOI: 10.13701/j.cnki.kqyxyj.2017.01.017
Abstract: 摘要 目的:比较3种自酸蚀粘结剂与3种树脂对牙齿V类洞的微渗漏的影响。方法:在45颗新鲜拔除的第三磨牙的颊舌侧颈部制备箱状(3 mm×2 mm×2 mm)V类洞。按随机数字法分为9组,每组有5颗牙齿,10个洞。有如下组合:A+D组(Easy one+Z350)、A+E组(Easy one+AP-X)、A+F组(Easy one+TPH)、B+D组(S3+Z350)、B+E组(S3+AP-X)、B+F组(S3+TPH)、C+D组(XV+Z350)、C+E组(XV+AP-X)、C+F组(XV+TPH)。按各粘结剂与复合树脂说明书方法,对每组洞进行相应的粘结剂和树脂充填。将牙放在37 ℃恒温水浴箱24 h后,室温下浸泡于1%的亚甲基蓝24 h,然后用金刚砂片将牙齿颊舌向切开为两半,在体式显微镜下观察微漏程度。结果:粘结剂S3 bond与不同树脂配伍使用时,其微渗漏存在显著性差异(P<0.05);粘结剂Easy one、Xeno V与不同树脂配伍使用时,其微渗漏不存在显著性差异;树脂Z350、可乐丽菲露AP-X与不同粘结剂配伍使用时,其结果存在显著性差异(P<0.05);树脂TPH与不同粘结剂使用时,其结果不存在显著性差异。结论:微渗漏的发生是粘结剂与树脂共同作用的结果。在临床用粘结剂与复合树脂修复V类洞时,应考虑其配伍性
Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia
Qin Li,Zhen Li,Xin-ying Xu,Yun-liang Guo,Fang Du
International Journal of Molecular Sciences , 2010, DOI: 10.3390/ijms11114580
Abstract: The aim of this study was to explore the effect of picroside II on neuronal apoptosis and the expression of caspase-3 and poly ADP-ribose polymerase (PARP) following middle cerebral artery occlusion/reperfusion in male Wistar rats. Picroside II (10 mg/kg) was administered intravenously into the tail vein of the animals. The neurological function deficits were evaluated with the Bederson’s test and the cerebral infarction volume was visualized with tetrazolium chloride (TTC) staining. The apoptotic cells were counted by in situ terminal deoxynucleotidyl transferase-mediated biotinylated deoxyuridine triphosphate nick end labeling (TUNEL) assay. The immunohistochemistry stain and enzyme linked immunosorbent assay (ELISA) was used to determine the expressions of caspase-3 and PARP in brain tissue. The results indicated that rats in the control group showed neurological function deficit and cerebral infarction in ischemic hemisphere after two hours ischemia followed by 22 hours reperfusion. Caspase-3 and PARP expressions were also profound in the cortex, the striatum and the hippocampus, along with increased apoptotic cells in this group. Bederson's score, infarction volume, and expressions of caspase-3 and PARP, as well as apoptosis in the treatment group were, however, significantly decreased compared to those in the control group indicating that intravenous treatment with picroside II might be beneficial to inhibit neuronal apoptosis and, thus, to improve the neurological function of rats upon cerebral ischemia reperfusion injury.
In silico identification of putative promoter motifs of White Spot Syndrome Virus
Hendrik Marks, Xin-Ying Ren, Hans Sandbrink, Mari?lle CW van Hulten, Just M Vlak
BMC Bioinformatics , 2006, DOI: 10.1186/1471-2105-7-309
Abstract: The collective information shows that the upstream region of early WSSV genes, containing a TATA box and an initiator, is similar to Drosophila RNA polymerase II core promoter sequences, suggesting utilization of the cellular transcription machinery for generating early transcripts. The alignment of the 5' ends of known well-established late genes, including all major structural protein genes, identified a degenerate motif (ATNAC) which could be involved in WSSV late transcription. For these genes, only one contained a functional TATA box. However, almost half of the WSSV late genes, as previously assigned by microarray analysis, did contain a TATA box in their upstream region.The data may suggest the presence of two separate classes of late WSSV genes, one exploiting the cellular RNA polymerase II system for mRNA synthesis and the other generating messengers by a new virus-induced transcription mechanism.White Spot Syndrome Virus (WSSV), type species of the virus family Nimaviridae (genus whispovirus), is a pathogen of major economic importance in cultured penaeid shrimp [1,2]. Histopathological studies on WSSV infected shrimp have shown that the virus mainly infects tissues of ectodermal and mesodermal origin, such as the stomach, gills, heart, gut, muscle tissue and hematopoietic tissue [3-5]. Infected cells within these tissues are characterized by the appearance of homogeneous hypertrophied nuclei and chromatin margination [1,5,6]. WSSV particles have been mainly detected in the nuclei of infected cells, indicating that transcription, replication and virion assembly probably occur in the nucleus [5-8]. It is not clear how the virions are released from the nucleus of an infected cell, but this most likely occurs by budding or by rupture of the nuclear envelope and/or the cell membrane.The circular ds DNA genome of three WSSV isolates, originating from Taiwan (WSSV-TW), China (WSSV-CN) and Thailand (WSSV-TH), have been completely sequenced [9-11]. The genome of W
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