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The present article studies the stability conditions of
central control artificial equilibrium generalized restricted problem of three
bodies. It is generalized in the sense that here we have taken the larger
primary body to be in shape of an oblate spheroid. The equilibrium
points are sought by the application of the propellant for which it would just
balance the gravitational forces. The launching flight of such a satellite is
seen to be applicable for having arbitrary space stations for these different
missions. Specialty of the result of the investigation lies in the fact that an
arbitrary space station can be formed to attain any specified mission.
Estrogen mediates multiple functions in the brain through the interaction of estrogen receptor (ER)α and ERβ with a host of nuclear proteins that regulate specific gene transcription. We have identified ERAP 140, AIB 1, Trk A, Src, pCREB and CREB as ERβ interacting proteins in the mouse brain. Earlier we showed that the interaction of ERβ with ERAP 140 decreased whereas its expression increased with aging in the brain of female mice. Here we report that the pattern of interaction and expression is different in male mice as compared to females. The interaction of ERAP 140 with ERβ decreased in adult male mouse brain as compared to young and remained almost similar in old whereas its expression was higher in adult than young and old, which were almost similar. Further in silico secondary structure analysis by self-optimized prediction method alignment (SOPMA) and PSIPRED revealed that ERβ interacting proteins were rich in alpha helices and coils. Such findings might help to design ER modulators which can regulate specific functions of estrogen in the brain during aging and degenerative diseases.