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Search Results: 1 - 10 of 403 matches for " Ganga Bisht "
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Memory Enhancing Effect of Ethanolic Extract of Stevia rebaudiana (Bert.)
Divya S Juyal,Ganga Bisht,Arun Kumar
International Journal of Phytomedicine , 2011,
Abstract: Suspension of ethanolic extract of leaves of Stevia rebaudiana bert. in gum acacia were administered orally to evaluate the memory enhancing activity in the aged rats. Memory enhancing effect was evaluated by using Morris water maze and elevated plus maze. Mean escape latency time (ELT) calculated each day during acquisition trial was used as an index of acquisition and mean time spent in target quadrant in search of missing platform provided an index of retrieval. Significant reduction in transfer latency (TL) value of retention indicated improvement of memory. Significant memory enhancing effect of ethanolic extract Stevia rebaudiana was observed in aged rats at 200 mg/kg p.o. dose. Keywords: Stevia rebaudiana, Memory, Alzheimer disease,
EFFECT OF Stevia rebaudiana (Bert.) EXTRACT ON MEMORY AND
Divya S Juyal,Ganga Bisht,arun kumar
Journal of Global Pharma Technology , 2010, DOI: 10.1234/jgpt.v2i5.173
Abstract: The present study was designed to investigate the effect of Stevia rebaudiana in age related cognition in old and young rats. Stevia rebaudiana extract (50, 100, 200mg/kg) was administered orally in old and young rats for sixteen days and were evaluated on Morris water maze, elevated plus maze and change in cholinesterase activity. Mean escape latency time (ELT) calculated each day during acquisition trial was used as an index of acquisition and mean time spent in target quadrant in search of missing platform provided an index of retrieval. Significant reduction in transfer latency (TL) value of retention indicated the improvement of memory. Significant memory enhancing and cholinesterase effect of aqueous extract Stevia rebaudiana was observed in aged rats at 200 mg/kg p.o. dose.
CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF SOLIDAGO CANADENSIS LINN. ROOT ESSENTIAL OIL
Devendra Mishra,Shivani Joshi,Ganga Bisht,Sangeeta Pilkhwal
Journal of Basic and Clinical Pharmacy , 2010,
Abstract: The essential oil from the roots of Solidago canadensis Linn. (fam. Asteraceae) was analyzed by GC, GC/MS and NMR spectroscopy. 39 constituents comprising 75.4% of the total oil were identified from the oil. Thymol constituted 20.25% of the oil followed by α-copaene (6.26%) and carvacrol (5.51%).The antimicrobial activity of the oil was evaluated using disc diffusion method. Results showed that the oil exhibited significant antibacterial activity against S. feacalis and E. coli whereas it showed moderate antifungal activity against C. albicans.
Chronomodulated drug delivery system: A comprehensive review on the recent advances in a new sub-discipline of ′chronopharmaceutics′
Bisht Rohit
Asian Journal of Pharmaceutics , 2011,
Abstract: With the advancement in the field of chronobiology, modern drug delivery approaches have been elevated to a new concept of chronopharmacology, that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. The mammalian circadian pacemaker resides in the paired suprachiasmatic nuclei and influences a multitude of biological processes, including the sleep-wake rhythm. Clock genes are the genes that control the circadian rhythms in physiology and behavior. Twenty-four hours rhythms are demonstrated for the function of physiology and the pathophysiology of diseases. The effectiveness and toxicity of many drugs vary depending on the dosing time. Such chronopharmacological phenomena are influenced by not only the pharmacodynamics, but also the pharmacokinetics of medications. The underlying mechanisms are associated with the 24-hour rhythms of biochemical, physiological, and behavioral processes under the control of the circadian clock. New technology for delivering medications precisely in a time-modulated fashion, by bedside or ambulatory pumps, is being developed to manage human diseases. From the point of view of pharmaceutics, the application of a biological rhythm to pharmacotherapy may be accomplished by the appropriate timing of conventionally formulated tablets and capsules, and a special drug delivery system, to synchronize the drug concentrations with the rhythms in the disease activity. Therefore, the present article gives an overview of the dosing time-dependent alterations in the therapeutic outcome and safety of the drug. The underlying mechanisms and usefulness are introduced from the point of view of chronopharmacology and chronotherapy.
Power Quality in Grid with Distributed Generation
Tanuj Bisht
International Journal of Trends in Economics Management and Technology , 2012,
Abstract: The main purpose of this paper is to discuss the basicunderstanding of power quality in relation to the distributedgeneration and renewable based distribution generation Due toconsiderable overlap between two technologies, disturbancesaffecting the power quality, which are mainly cause by theaddition of Distributed Generation on the existing power systemnetwork. Injection of the DG into an electric power grid canaffect the voltage quality. Distributed generation of differentvoltage levels when connected to the power system networkcould influence the voltage regulation, sustained interruptions,harmonics, sags, swells, etc. The role of CPDs in enhancing theintegration of renewable and providing quality power throughcustoms power park are described.
Who is A Child? : The Adults’ Perspective within Adult-Child Relationship in India
Rachita Bisht
Interpersona : An International Journal on Personal Relationships , 2008,
Abstract: Based on the assumption that childhood is a social construct, this qualitative study explores how children across ages, are perceived by adults. Using modified grounded theory approach, seven adults, teachers by profession, were informally interviewed over several sessions, supplemented by TAT-like picture cards. Theoretical coding led to the extraction of the following key themes. To begin with, participants divided childhood into several phases, each characterized by distinct adult-child relationship and interaction. Secondly, compared to earlier times, children of today were seen as maturing faster along with greater democratization in adult-child relationships. And finally, analysis of social position of children in participants’ interviews showed that children were being perceived using an ideology of dependency and incompetency that manifested in various marginalizing practices within adult-child relationship.
Vorinostat: A Novel Anti Cancer Drug
Manisha Bisht,S S Bisht
JK Science : Journal of Medical Education & Research , 2009,
Abstract: Vorinostat has shown promising clinical activity againstthe treatment of advanced solid tumors, colorectal cancer,hematological malignancies and recurrent glioblastomamultiforme at doses that have been well toleratedby patients.
Effect of Different Electrodes and Process Variables On Material Removal Rate and Surface Roughness in Electrochemical Machining
GANGA SAGAR
International Journal of Advances in Engineering Sciences , 2011,
Abstract: Studies on Material removal rate (MRR) and surface roughness (Ra) are of greatest importance in ECM, since it is one of the determining factors in the process decisions. This research deals that to investigate the effect of different electrodes and process variables on the material removal rate and surface roughness of electrochemical machining (ECM) on EN8 alloy steel component.In this experimental study, Design of Experiment Method has been employed to find out the effects of different electrodes (copper and aluminium) and process variables (feed rate, flow rate of the electrolyte and voltage) on material removal rate and surface roughness. ANOVA and Regression analysis is performed to estimate the characteristics in terms of the values of the machining parameters by the use of DOE++ software.
Effect of Query Formation on Web Search Engine Results
Raj Kishor Bisht,Ila Pant Bisht
Computer Science , 2013,
Abstract: Query in a search engine is generally based on natural language. A query can be expressed in more than one way without changing its meaning as it depends on thinking of human being at a particular moment. Aim of the searcher is to get most relevant results immaterial of how the query has been expressed. In the present paper, we have examined the results of search engine for change in coverage and similarity of first few results when a query is entered in two semantically same but in different formats. Searching has been made through Google search engine. Fifteen pairs of queries have been chosen for the study. The t-test has been used for the purpose and the results have been checked on the basis of total documents found, similarity of first five and first ten documents found in the results of a query entered in two different formats. It has been found that the total coverage is same but first few results are significantly different.
Common Fixed Points of Generalized Meir-Keeler Type Condition and Nonexpansive Mappings
R. K. Bisht
International Journal of Mathematics and Mathematical Sciences , 2012, DOI: 10.1155/2012/786814
Abstract: The aim of the present paper is to obtain common fixed point theorems by employing the recently introduced notion of weak reciprocal continuity. The new notion is a proper generalization of reciprocal continuity and is applicable to compatible mappings as well as noncompatible mappings. We demonstrate that weak reciprocal continuity ensures the existence of common fixed points under contractive conditions, which otherwise do not ensure the existence of fixed points. Our results generalize and extend Banach contraction principle and Meir-Keeler-type fixed point theorem.
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