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Search Results: 1 - 10 of 219025 matches for " G.; Martínez-Aran "
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Motor speed predicts stability of cognitive deficits in both schizophrenic and bipolar I patients at one-year follow-up
J. Salazar-Fraile,V. Balanzá-Martínez,G. Selva-Vera,A. Martínez-Aran
The European Journal of Psychiatry , 2009,
Abstract: Background: We examined whether motor speed assessed by the finger tapping test predicts generalized and specific stable deficits because of a common pathogenic process in bipolar and schizophrenic patients. Methods: One hundred and two patients underwent a battery of neuropsychological tests. Patients with a score of less than one standard deviation from their siblings', sample in two assessments with an interval of one year were defined as suffering from stable deficits because of a common pathogenic process. In addition to univariate analyses, factor analyses, ordinal logistic regression, and multiple linear regressions were used. A general score was also calculated. Results: No differences were found between schizophrenic and bipolar patients in the deficits of verbal fluency, shift reasoning ability and executive attention. Schizophrenic patients had greater persistent cognitive deficit because of a common pathogenic factor in the verbal memory dimension than bipolar patients. Motor speed predicted the specific deficits of verbal fluency, shift reasoning, executive attention and the general deficit of both bipolar I and schizophrenic patients. Bipolar patients suffered a lesser specific deficit in the verbal memory dimension than schizophrenic patients did, this domain not being predicted by motor speed. Motor speed predicted the generalized deficit and the specific dimensions in which schizophrenic and bipolar patients showed no differences. Conclusions: These results suggest the presence of general and specific stable cognitive deficits because of a common pathogenic factor related to psychomotor slowness. Motor speed seems to be suitable endophenocognitype for schizophrenia and bipolar disorder.
Motor speed predicts stability of cognitive deficits in both schizophrenic and bipolar I patients at one-year follow-up
Salazar-Fraile,J.; Balanzá-Martínez,V.; Selva-Vera,G.; Martínez-Aran,A.; Sánchez-Moreno,J.; Rubio,C.; Vieta,E.; Gómez-Beneyto,M.; Tabarés-Seisdedos,R.;
The European Journal of Psychiatry , 2009, DOI: 10.4321/S0213-61632009000300007
Abstract: background: we examined whether motor speed assessed by the finger tapping test predicts generalized and specific stable deficits because of a common pathogenic process in bipolar and schizophrenic patients. methods: one hundred and two patients underwent a battery of neuropsychological tests. patients with a score of less than one standard deviation from their siblings', sample in two assessments with an interval of one year were defined as suffering from stable deficits because of a common pathogenic process. in addition to univariate analyses, factor analyses, ordinal logistic regression, and multiple linear regressions were used. a general score was also calculated. results: no differences were found between schizophrenic and bipolar patients in the deficits of verbal fluency, shift reasoning ability and executive attention. schizophrenic patients had greater persistent cognitive deficit because of a common pathogenic factor in the verbal memory dimension than bipolar patients. motor speed predicted the specific deficits of verbal fluency, shift reasoning, executive attention and the general deficit of both bipolar i and schizophrenic patients. bipolar patients suffered a lesser specific deficit in the verbal memory dimension than schizophrenic patients did, this domain not being predicted by motor speed. motor speed predicted the generalized deficit and the specific dimensions in which schizophrenic and bipolar patients showed no differences. conclusions: these results suggest the presence of general and specific stable cognitive deficits because of a common pathogenic factor related to psychomotor slowness. motor speed seems to be suitable endophenocognitype for schizophrenia and bipolar disorder.
Validity and reliability of the Functioning Assessment Short Test (FAST) in bipolar disorder
Rosa Adriane R,Sánchez-Moreno Jose,Martínez-Aran Anabel,Salamero Manel
Clinical Practice and Epidemiology in Mental Health , 2007, DOI: 10.1186/1745-0179-3-5
Abstract: Background Numerous studies have documented high rates of functional impairment among bipolar disorder (BD) patients, even during phases of remission. However, the majority of the available instruments used to assess functioning have focused on global measures of functional recovery rather than specific domains of psychosocial functioning. In this context, the Functioning Assessment Short Test (FAST) is a brief instrument designed to assess the main functioning problems experienced by psychiatric patients, particularly bipolar patients. It comprises 24 items that assess impairment or disability in six specific areas of functioning: autonomy, occupational functioning, cognitive functioning, financial issues, interpersonal relationships and leisure time. Methods 101 patients with DSM-IV TR bipolar disorder and 61 healthy controls were assessed in the Bipolar Disorder Program, Hospital Clinic of Barcelona. The psychometric properties of FAST (feasibility, internal consistency, concurrent validity, discriminant validity (euthymic vs acute patients), factorial analyses, and test-retest reliability) were analysed. Results The internal consistency obtained was very high with a Cronbach's alpha of 0.909. A highly significant negative correlation with GAF was obtained (r = -0.903; p < 0.001) pointing to a reasonable degree of concurrent validity. Test-retest reliability analysis showed a strong correlation between the two measures carried out one week apart (ICC = 0.98; p < 0.001). The total FAST scores were lower in euthymic (18.55 ± 13.19; F = 35.43; p < 0.001) patients, as compared with manic (40.44 ± 9.15) and depressive patients (43.21 ± 13.34). Conclusion The FAST showed strong psychometrics properties and was able to detect differences between euthymic and acute BD patients. In addition, it is a short (6 minutes) simple interview-administered instrument, which is easy to apply and requires only a short period of time for its application.
Hidatidosis humana: antecedentes generales y situación epidemiológica en Chile, 2001-2009
Martínez G,Paulina;
Revista chilena de infectología , 2011, DOI: 10.4067/S0716-10182011000700013
Abstract: objective: to characterize the epidemiology of human hydatidosis in chile. material: data from the mandatory disease notification system (2001-2009), hospital discharges (2001-2008), deaths (2001-2008) and years of potential life lost (2001-2008) were analyzed. results: the average incidence, according to the mandatory notification data, was 1.9 cases per 100,000 inhabitants (men 51.4%). median age was 38 years. hospital discharge rate for the period was 6.3 discharges per 100,000 inhabitants. the main diagnosis corresponded to b67.9 (echino-coccosis, other and unspecified). the average mortality rate was 0.2 deaths per 100,000 inhabitants. the level of education of fatalities was mainly basic. there was a loss of 3.349 years of life due to the premature death of 235 people. conclusions: the incidence rates of cases reported, hospital discharges and mortality tend to decrease. there is a noteworthy discrepancy between reported cases and hospital discharges, which suggests underreporting. improvement of the notification system and additional prevalence studies are required.
Composición corporal: Su importancia en la práctica clínica y algunas técnicas relativamente sencillas para su evaluación
Martínez,Emilio G.;
Revista Salud Uninorte , 2010,
Abstract: the control and prevention of malnutrition is an unfinished task in many countries, including colombia. at the same time, chronic diseases related to nutrition are now the leading cause of disability and death, not only globally but also in many developing countries. in colombia as in most countries, traditionally have been used as anthropometric criteria like indices of weight, height and body mass index (i) to define obesity, malnutrition and eating disorders, but these variables have little sensitivity to monitor treatment response and that is why the assessment of body composition may qualify this process. the aim of this paper is to review some relatively simple techniques for assessing body composition and its advantages and disadvantages in clinical practice for monitoring patients. while obesity adversely impacts in the short-term health, there is growing evidence that cardiovascular disease has its origins in childhood and adolescence, so that regardless of body composition in adult life, elevated levels adiposity in childhood may by themselves increase the risk of disease later. it is a priority for universities, health institutions and policy makers in health, to stimulate national research in this field in order to achieve the development of national benchmarks.
Gametófitos y esporófitos jóvenes de cuatro especies de helechos del género Pteris (Pteridaceae) naturalizadas en América
Martínez,Olga G;
Revista de Biología Tropical , 2010,
Abstract: gametophytes and young sporophytes of four species of the fern genus pteris (pteridaceae) naturalized in the american continent. the pantropical fern genus pteris l. has about 250 species of which 60 occur in the american continent. we studied the morphogenesis of the gametophyte, and the morphology of the young sporophytes of four species: p. cretica, p. ensiformis, p. multifida and p.vittata, together with a palynological analysis that includes the ability of spores to germinate. gametophytes were obtained trough in vitro culture techniques with agar-gellified knudson medium. young sporophytes were placed in earth-sand (3:1) sterile substrate. we used light and sem microscopy. triletes spores predominate, but monolete, tetralete, and other types of apertura are often found. the viability of spores is not affected by the variation, so the term spore polymorphism is applied to the condition occurring among these species. spore polymorphism is similar in p. cretica and p. multifida. germination occurs following the vittaria type, 3-7 days after the sowing. filamentous, 3-5 celled gametophytes were found in p. cretica, p. multifida and p. vittata, and 7-9 celled in p. ensiformis. development of gametophytes takes place following adiantum type and eratopteris type. the symmetry of the laminae differ in gametophytes, those of p. ensiformis and p. multifida are similar and differ from the other two species, p. cretica and p. vittata. gametophytes of p. ensiformis, p. multifida and p. vittata are bisexual and protandric, while male gametophytes were found in p. cretica. antheridia correspond to the common leptosporangiate type; they are cylindric in p. vittata and ovoid in the other three species. archegonia necks have 4 rows of 4 cells each. the sporophytes complete their development 3 months after sowing, and have indument close to the adult plants. p. cretica shows obligated apogamy. rev. biol. trop. 58 (1): 89-102. epub 2010 march 01.
Hidatidosis humana: antecedentes generales y situación epidemiológica en Chile, 2001-2009 Human hydatidosis disease: general background and epidemiological situation in Chile, 2001-2009
Paulina Martínez G
Revista chilena de infectología , 2011,
Abstract: Objetivo: Caracterizar epidemiológicamente la hidatidosis humana en Chile. Material: Se utilizaron datos del Sistema de Notificación Obligatoria (2001-2009), Egresos hospitalarios (2001-2008), Defunciones (2001-2008) y A os de Vida Potencialmente Perdidos (2001-2008). Resultados: La incidencia promedio, según las notificaciones obligatorias fue 1,9 casos por 100 mil habs. (hombres 51,4%). Edad mediana 38 a os. Egresos hospitalarios presentaron una tasa promedio de 6,3 egresos por 100 mil habs. El mayor diagnostico fue B67.9 (equinococosis, otra y la no especificada). La tasa de mortalidad promedio fue 0,2 defunciones por 100 mil habs. El nivel de instrucción de los afectados fue mayoritariamente básico. Se produjo la pérdida de 3.349 a os de vida por el fallecimiento prematuro de 235 personas. Conclusiones: Las tasas de incidencia de casos notificados, egresos hospitalarios y mortalidad tienden a disminuir. Llama la atención la incongruencia entre los casos notificados y egresos hospitalarios, lo cual sugiere una sub-notificación. Se recomienda potenciar el sistema de notificación, confirmación de casos y estimular estudios de prevalencia. Objective: To characterize the epidemiology of human hydatidosis in Chile. Material: Data from the Mandatory Disease Notification System (2001-2009), hospital discharges (2001-2008), Deaths (2001-2008) and Years of Potential Life Lost (2001-2008) were analyzed. Results: The average incidence, according to the mandatory notification data, was 1.9 cases per 100,000 inhabitants (men 51.4%). Median age was 38 years. Hospital discharge rate for the period was 6.3 discharges per 100,000 inhabitants. The main diagnosis corresponded to B67.9 (Echino-coccosis, other and unspecified). The average mortality rate was 0.2 deaths per 100,000 inhabitants. The level of education of fatalities was mainly basic. There was a loss of 3.349 years of life due to the premature death of 235 people. Conclusions: The incidence rates of cases reported, hospital discharges and mortality tend to decrease. There is a noteworthy discrepancy between reported cases and hospital discharges, which suggests underreporting. Improvement of the notification system and additional prevalence studies are required.
Gametófitos y esporófitos jóvenes de cuatro especies de helechos del género Pteris (Pteridaceae) naturalizadas en América
Olga G Martínez
Revista de Biología Tropical , 2010,
Abstract: El género pantropical Pteris L. tiene 250 especies de la cuales 60 están en el continente Americano. Se estudió la morfogénesis de los gametófitos, y la morfología de los esporófitos jóvenes de cuatro especies: P. cretica, P. ensiformis, P. multifida y P.vittata, junto con un análisis palinológico que incluye la capacidad de las esporas de germinar. Los gametófitos se obtuvieron mediante técnicas de cultivo in vitro. Los esporófitos jóvenes se trasladaron a sustrato estéril de tierra y arena (3:1). Se usó el microscopio de luz y el de barrido (SEM). Se encontraron esporas con diferentes tipos de aperturas. La germinación ocurre entre 3-7 días y corresponde al tipo Vittaria. Se encontraron gametófitos filamentosos formados por 3-5 células en P. cretica, P. multifida y P. vittata y por 7-9 células en P. ensiformis. El desarrollo gametofítico ocurre de dos formas: tipo Adiantum y tipo Ceratopteris. Los gametófitos de P. ensiformis, P. multifida y P. vittata son monoicos y protándricos. P. cretica desarrolla gametófitos anteridiados. Los anteridios corresponden al tipo común de los helechos leptosporangiados, son cilíndricos en P. vittata y ovoides en las otras tres especies. Los cuellos de los arquegonios tienen 4 hileras con 4 células cada una. Los esporófitos se desarrollan después de los 3 meses de su siembra y su indumento es semejante a las plantas adultas. P. cretica presenta apogamia obligada. Gametophytes and young sporophytes of four species of the fern genus Pteris (Pteridaceae) naturalized in the American continent. The pantropical fern genus Pteris L. has about 250 species of which 60 occur in the American continent. We studied the morphogenesis of the gametophyte, and the morphology of the young sporophytes of four species: P. cretica, P. ensiformis, P. multifida and P.vittata, together with a palynological analysis that includes the ability of spores to germinate. Gametophytes were obtained trough in vitro culture techniques with agar-gellified Knudson medium. Young sporophytes were placed in earth-sand (3:1) sterile substrate. We used light and SEM microscopy. Triletes spores predominate, but monolete, tetralete, and other types of apertura are often found. The viability of spores is not affected by the variation, so the term spore polymorphism is applied to the condition occurring among these species. Spore polymorphism is similar in P. cretica and P. multifida. Germination occurs following the Vittaria type, 3-7 days after the sowing. Filamentous, 3-5 celled gametophytes were found in P. cretica, P. multifida and P. vittata, and 7-9 celled
Composición corporal: Su importancia en la práctica clínica y algunas técnicas relativamente sencillas para su evaluación
Emilio G. Martínez
Revista Salud Uninorte , 2010,
Abstract: El control y la prevención de la desnutrición es una tarea inconclusa en muchos países, entre ellos Colombia. Al mismo tiempo, enfermedades crónicas relacionadas con la nutrición son ahora la principal causa de discapacidad y muerte, no sólo a nivel global sino también en muchos de los países en vías de desarrollo. En Colombia, al igual que en la mayoría de los países, tradicionalmente se han utilizado criterios antropométricos, como los índices de peso, talla y el índice de masa corporal (IMC), para definir la obesidad, la desnutrición y los trastornos alimentarios, pero estas variables poseen poca sensibilidad para monitorear la respuesta al tratamiento, y es por eso que la evaluación de la composición corporal puede cualificar este proceso. El objetivo de este artículo es revisar algunas técnicas relativamente sencillas para evaluar la composición corporal y sus ventajas y desventajas en la práctica clínica para el seguimiento de los pacientes. Mientras la obesidad impacta de manera adversa en el corto plazo la salud, existe una evidencia creciente de que las enfermedades cardiovasculares tienen su origen en la ni ez y la adolescencia, de manera que, independientemente de la composición corporal en la vida adulta, los niveles elevados de adiposidad en la ni ez pudieran por sí solos incrementar el riesgo de enfermedades posteriormente. Es una prioridad para las universidades, las instituciones de salud y los encargados de las políticas en salud estimular la investigación nacional en este campo, con el objetivo de alcanzar el desarrollo de valores de referencia nacionales.
Teratocarcinosarcoma rinosinusal: Reporte de un caso
González G,Claudia; I?iguez,Rodrigo; Aranís Jiménez,Carolina; Castiblanco Galvis,Adriana;
Revista de otorrinolaringología y cirugía de cabeza y cuello , 2008, DOI: 10.4067/S0718-48162008000400008
Abstract: rhinosinusal teratocarcinosarcoma is a rare malignant neoplasm, which combines teratoma and carcinoma elements. it is composed of benign or malignant epithelium (fibroblasts), mesenchymatic (cartilage, bone or smooth muscle) and neural elements. until 2008, a total of63 cases of rhinosinusal location have been reponed. we present the case of a nasal cavity teratocarcinosarcoma ?n a 67 year oíd man that presented with rapidly progressing nasal obstruction. the lesión was completely resected by endoscopic approach. diagnosis was confirmed by histoiogicai pathoiogy and immunohistochemistry additional treatment by radiotherapy was administered, with no evidence of recurrences a year after surgery.
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