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Search Results: 1 - 10 of 224855 matches for " G.; Delgado-Hernández "
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Modelos animales de dolor y electroacupuntura
Garrido,B.; Bosch,F.; Garrido,G.; Hernández-Balmaseda,I.; Delgado-Hernández,R.;
Revista de la Sociedad Espa?ola del Dolor , 2007,
Abstract: animal models of pain have permitted in the last decades important advances in neurobiologic research, but biological systems are not exact and there are múltiple factors that can lead to contradictory results. those difficulties are exacerbated in models addressed to electroacupuncture treatment procedures, as a parametric variability exists for the liberation of mediators, also for the response of biochemical systems manipulated under physiologic or pathological conditions, among other the influence of the stress induced analgesia (sia). our purpose is to critically analyze some recent experiments in this field, from authors that have faced these difficulties and still have provided important elements for the clarification of the mechanisms involved in acupuncture analgesia.
Utilidad del Extracto de Mangifera Indica L (VIMANG) en el Síndrome Doloroso Regional Complejo: A propósito de un caso Usefulness of Mangifera Indica L (Vimang ) in the treatment of Complex Regional Pain Syndrome (CRPS): A case report
B. Garrido-Suárez,F. Bosch,G. Garrido-Garrido,R. Delgado-Hernández
Revista de la Sociedad Espa?ola del Dolor , 2007,
Abstract: Los avances en el conocimiento actual de la fisiopatología del Síndrome Doloroso Regional Complejo (SDRC), conducen a la búsqueda de nuevos fármacos dirigidos a los blancos moleculares que se involucran en sus complejos mecanismos. En la actualidad se considera el papel activo de la neuroinflamación en el fenómeno de hiperexcitabilidad del cuerno dorsal espinal y el establecimiento de la sensibilización central dentro de sus procesos subyacentes. El Extracto obtenido de la corteza de variedades seleccionadas de la especie Mangifera indica L. y que se comercializa en Cuba bajo la Marca Registrada VIMANG , posee actividad antioxidante, antiinflamatoria y antihiperalgésica in vivo. Por otra parte estudios in vitro demostraron su efecto inhibidor sobre múltiples moléculas que participan en la cascada de la sensibilización central y en un modelo de isquemia-reperfusión sus cualidades neuroprotectoras. Presentamos el caso de una paciente con diagnóstico de SDRC tipo II, secundario a una lesión del plexo braquial, con sección del nervio radial a nivel humeral que fue provocada por el desplazamiento de la fractura del húmero izquierdo. La paciente llega a nuestro servicio a los 4 meses de evolución, con síntomas sensoriales, dolor persistente quemante y paroxístico, alodinia mecánica, edema, cambios vasomotores hacia la hiperhemia y mano en flexión por pérdida de la función motora de los músculos extensores del antebrazo. Con compromiso de la articulación del carpo y hombro de limitación severa y dolor de valor 5 en una escala numérica de Likert. El estudio de conducción nerviosa mostró alteraciones mielínico-axonales discretas del nervio mediano y mielínico-axonales severas del nervio radial. Se instauró el tratamiento con Vimang (300mg) 2 tabletas cada 8 horas por 4 meses y la aplicación local de la crema Vimang 3 veces al día, asociado a los bloqueos simpáticos y somáticos para miembro superior y a la fisioterapia. La evolución clínica y electrofisiológica fue muy favorable. Este caso constituye el primero descrito en la literatura, en el cual se introduce este producto a la terapia múltiple del síndrome, se deben dirigir los estudios básicos y clínicos en este sentido, dadas las posibilidades terapéuticas del Vimang en el SDRC. Advances in our understanding of Complex Regional Pain Syndrome (CRPS) physiopathology have led to new drugs targeted toward molecular mediators involved in the complex mechanisms of pain. Neuroinflammation is thought to have an active role in phenomena underlying spinal cord dorsal horn hyperexcitability and the establishment of cen
Introducción de la suplementación con formulaciones Vimang? en el síndrome doloroso regional complejo: experiencia en 15 pacientes
Garrido-Suárez,B.; Rabí,M.C.; Bosch,F.; Garrido-Garrido,G.; Delgado-Hernández,R.;
Revista de la Sociedad Espa?ola del Dolor , 2009,
Abstract: introduction: currently, oxidative stress, neuroinflammation and glial activation are accepted as playing a pathophysiological role in complex regional pain syndrome (crps) and consequently antioxidant agents and proinfl ammatory cytokine inhibitors have begun to be assessed in the treatment of this disorder. vimang? is a new phytodrug prepared from the stem bark of mangifera indica l., registered in cuba with inhibitory effect on nuclear transcription factor kb (nfkb), which induces expression of some mediators and enzymes involved in inflammation, oxidative stress, pain, and synaptic plasticity. objective: to determine the analgesic effects of vimang? tablets and 1.2% cream as a topical agent in 15 patients with crps, as well as possible improvement in post-treatment functional capacity. material and methods: the patients received a daily dose of 1800 mg of vimang? tablets for 120 days, 1.2% cream in the affected limb 3 times/day, and sympathetic blocks once a week for 4 months. physiotherapy was introduced after 30 days. the variables evaluated were changes in average daily pain score through a likert scale, the area and rate of dynamic mechanical allodynia, rate of cold allodynia, deep somatic allodynia and frequency of burning spontaneous pain. a modified scale of enneking et al. was applied to evaluate functional capacity. results: the average daily pain score and sensory abnormalities significantly improved from week 2-3. on average, the functional capacity of the affected limb increased from 22.7 % to 78.7%. our results suggest that vimang? formulations might be useful in crps treatment. however, further studies are required.
Utilidad del Extracto de Mangifera Indica L (VIMANG) en el Síndrome Doloroso Regional Complejo: A propósito de un caso
Garrido-Suárez,B.; Bosch,F.; Garrido-Garrido,G.; Delgado-Hernández,R.; Porro,J. N.; Manero,J. M.;
Revista de la Sociedad Espa?ola del Dolor , 2007,
Abstract: advances in our understanding of complex regional pain syndrome (crps) physiopathology have led to new drugs targeted toward molecular mediators involved in the complex mechanisms of pain. neuroinflammation is thought to have an active role in phenomena underlying spinal cord dorsal horn hyperexcitability and the establishment of central sensitivity. an extract from the bark of selected mangifera indica l species, registered under the vimang? trade mark in cuba, has antioxidant, anti-inflammatory and antihyperanalgesic activity in vivo. in vitro studies have demonstrated that it has an inhibitory effect on several molecules mediating the central sensitization cascade and an ischemic-reperfusion model has proved its cerebral neuroprotective qualities. we present a patient with type ii crps secondary to a brachial plexus lesión following a displaced left humerus fracture that sectioned the radius nerve. the patient presented in our pain clinic four months after the accident with sensorial symptoms, persistent burning pain mechanical allodynia, oedema, vasomotor alterations tending to hyperhaemia and a flexed hand due to loss of the motor function in the fore arm extensors. carpal and shoulder joint movement was severely limited and she scored 5 on the likert pain scale. electrophysiological study revealed mild myelin-axonal alterations in the median nerve and severe alterations in the radial nerve. treatment with vimang (300 mg; 2 tablets/8 hours/4 months) with topical administration of vimang cream 3 times per day combined with sympathetic and somatic nerve blocks in the upper limb and physiotherapy were begun. the patient's clinical and electrophysiological evolution was very favourable. this is the first description of the use of this product in combined crps therapy. our results indicate that further basic and clinical research into the use of vimang? for crps is justified.
Consideraciones técnicas de los estándares de radiodifusión terrestre DAB e IBOC
Moumtadi, F;Delgado-Hernández, J.C.;Vicente-Vivas, E;
Ingeniería, investigación y tecnología , 2011,
Abstract: the development of digital radiobroadcast standards and the advantages related to it (optimization of video, audio and applications transmission and services) makes indispensable the study of its technical characteristics, due to the definition, over common parameters, of the advantages of each standard by itself and in comparison to others. in this paper the basic technical characteristics of two terrestrial digital radiobroadcasting standards are shown: on one hand, the so called "in-band-on-channel" (iboc) and, on the other, the "digital audio broadcast" (dab) standard. the analysis compares the data management procedures of the standards and its relation with the open systems interconnection model - osi, that opens the possibility to make a real comparison between them. at the end it is concluded that, technologically, the possibility for radio stations to use their actual infrastructure without capital modifications and / or enhancements, makes iboc a clear option of implementation for digital radiobroadcasting in countries like mexico.
Definición del nivel de interferencias en la transmisión de se?ales digitales de radiodifusión en modo híbrido
Moumtadi, F.;Delgado-Hernández, J.C.;Rodríguez-Huerta, J.;
Ingeniería, investigación y tecnología , 2012,
Abstract: one of the most important strategies developed to boost the commercial introduction of new digital radiobroadcast standards is based on the use of the present am transmission infrastructure to send both analog and digital signals over the same medium and range of frequencies through a suitable scheme of modulation. this mode of transmission is denominated "hybrid mode", and is based on the use of the keeper range of frequencies between carriers of analogical transmission to send the digital signals. however, radiobroadcast over adjacent frequencies with minimal guard intervals between them could generate interference on the digital information under certain circumstances. in this work the transmission of both in band - on channel (am iboc) and digital radio mondiale (drm) digital standards, broadcasting in hybrid mode from adjacent frequencies is analyzed through the use of models, and the implications of the phenomenon and its possible solutions are concluded, taking as example the case of three commercial stations nowadays operating in mexico city.
Transmission Interferences Level Measurement for Digital Audiobroadcasting Signals Transmitted on Hybrid Mode
Moumtadi F.,Delgado-Hernández J.C.,Rodríguez-Huerta J.
Ingeniería, investigación y tecnología , 2012,
Abstract: One of the most important strategies developed to boost the commercial introduction of new digital radiobroadcast standards is based on the use of the present AM transmission infrastructure to send both analog and digital signals over the same medium and range of frequencies through a suitable scheme of modulation. This mode of transmission is denominated “hybrid mode”, and is based on the use of the keeper range of frequencies between carriers of analogical transmission to send the digital signals. However, radiobroadcast over adjacent frequencies with minimal guard intervals between them could generate interference on the digital information under certain circumstances. In this work the transmission of both In Band – On Channel (AM IBOC) and Digital Radio Mondiale (DRM) digital standards, broadcasting in hybrid mode from adjacent frequencies is analyzed through the use of models, and the implications of the phenomenon and its possible solutions are concluded, taking as example the case of three commercial stations nowadays operating in Mexico City.
Technical Aspects of DAB and IBOC Terrestrial Digital Radio Broadcasting Standards
Moumtadi F.,Delgado-Hernández J.C.,Vicente-Vivas E.
Ingeniería, investigación y tecnología , 2011,
Abstract: The development of digital radiobroadcast standards and the advantages related to it (optimization of video, audio and applications transmission and services) makes indispensable the study of its technical characteristics, due to the definition, over common parameters, of the advantages of each standard by itself and in comparison to others. In this paper the basic technical characteristics of two terrestrial digital radiobroadcasting standards are shown: on one hand, the so called “In-Band-On-Channel” (IBOC) and, on the other, the “Digital Audio Broadcast” (DAB) standard. The analysis compares the data management procedures of the standards and its relation with the open systems interconnection model – OSI, that opens the possibility to make a real comparison between them. At the end it is concluded that, technologically, the possibility for radio stations to use their actual infrastructure without capital modifications and / or enhancements, makes IBOC a clear option of implementation for digital radiobroadcasting in countries like Mexico.
Customer Need s Satisfaction in the Housing Sector: the Case of the Toluca Valley
Delgado-Hernández David Joaquín,Romero-Ancira Liliana
Ingeniería, investigación y tecnología , 2013,
Abstract: Currently, the construction sector faces great challenges, as the recent economic contraction has directly impacted this industry, and only companies that can offer quality products and services will survive in today’s highly competitive markets. In particular, the housing sector has to find ways to meet the needs of its customers due to the number of firms competing in this arena. There are some studies that quantify the demand for housing as well as those that reveal the number of homes sold per year in a region. However, investigations in Mexico to establish the level of cus- tomer satisfaction with their homes are still scarce. Thus, the main objective of this research is to determine the level of customer satisfaction in the Toluca Valley s housing sector (a region located 60 km west of Mexico City), in low income projects developed by Mexican construction companies. Having applied a questionnaire to users from seventy eight houses within eight different projects, some issues were identified that builders could improve, and take into account during the design stage of new housing developments. Among the main ones are: insulation, wall and ceil- ing materials, space distribution, and house s size. In contrast, residents are rela- tively satisfied with: the ease of cleaning, the aesthetics of the projects and the proximity to schools and supermarkets.
Be abundances in cool main-sequence stars with exoplanets
E. Delgado Mena,G. Israelian,J. I. González Hernández,N. C. Santos,R. Rebolo
Physics , 2011, DOI: 10.1088/0004-637X/746/1/47
Abstract: We present new UVES spectra of a sample of 15 cool unevolved stars with and without detected planetary companions. Together with previous determinations, we study Be depletion and possible differences in Be abundances between both groups of stars. We obtain a final sample of 89 and 40 stars with and without planets, respectively, which covers a wide range of effective temperatures, from 4700 K to 6400 K, and includes several cool dwarf stars for the first time. We determine Be abundances for these stars and find that for most of them (the coolest ones) the BeII resonance lines are often undetectable, implying significant Be depletion. While for hot stars Be abundances are aproximately constant, with a slight fall as Teff decreases and the Li-Be gap around 6300 K, we find a steep drop of Be content as Teff decreases for Teff < 5500 K, confirming the results of previous papers. Therefore, for these stars there is an unknown mechanism destroying Be that is not reflected in current models of Be depletion. Moreover, this strong Be depletion in cool objects takes place for all the stars regardless of the presence of planets, thus, the effect of extra Li depletion in solar-type stars with planets when compared with stars without detected planets does not seem to be present for Be, although the number of stars at those temperatures is still small to reach a final conclusion.
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