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Search Results: 1 - 10 of 248015 matches for " G. Yu "
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Effects of extracellular matrix proteins on expansion, proliferation and insulin-producing-cell differentiation of ARIP cells  [PDF]
Gary G. Adams, Yu-Xin Cui
Journal of Biomedical Science and Engineering (JBiSE) , 2009, DOI: 10.4236/jbise.2009.24035
Abstract: Regeneration of transplantable pancreatic islet cells has been considered to be a promising alternative therapy for type 1 diabetes. Re-search has suggested that adult pancreatic stem and progenitor cells can be derived into insulin-producing cells or cultivated islet-like clusters given appropriate stimulating condi- tions. In this study we explored the effect of selective extracellular matrix (ECM) proteins on the potential of insulin-producing cell differen-tiation using ARIP cells, an adult rat pancreatic ductal epithelial cell line, as a model in vitro. Quantitative single cell morphology analysis indicated that all the four ECM proteins we have used (type I collagen, laminin, fibronectin and vitronectin) increased the single cell area and diameter of ARIP cells. In addition, se-rum-free cell cultivation was dependent on cell density and particular components; and serum could be replaced when systematic optimisa-tion could be performed. Surface treated with laminin was shown to be able to enhance overall cell expansion in the presence of de-fined serum-free medium conditions. Collagen treated surfaces enhanced insulin production in the presence of GLP-1 although the insulin gene expression was however weak accord-ingly. Our results suggest that selective ECM proteins have effects on single cell morphol-ogy, adhesion and proliferation of ARIP cells. These ECM molecules however do not have a potent effect on the insulin-producing cell dif-ferentiation potential of ARIP cells even com-bining with GLP-1.
Finite Element Analysis of Sound Transmission Loss in One-Dimensional Solids  [PDF]
S. D. Yu, J. G. Kawall
Open Journal of Acoustics (OJA) , 2013, DOI: 10.4236/oja.2013.34017

A higher-order acoustic-displacement based finite element procedure is presented in this paper to investigate one-dimensional sound propagation through a solid and the associated transmission loss. The acoustic system consists of columns of standard air and a solid, with the upstream column of air subjected to a sinusoidal sound source. The longitudinal wave propagation in each medium is modeled using three-node finite elements. At the interfaces between the air and the solid medium, the continuity in acoustic displacements and the force equilibrium conditions are enforced. The Lagrange multipliers method is utilized to assemble the global equations of motion for the acoustic system. Numerical results obtained for various test cases using the procedure described in the paper are in excellent agreement with the analytical solutions and other independent solutions available in the literature.

Late Cenozoic Tectonic Uplift Producing Mountain Building in Comparison with Mantle Structure in the Alpine-Himalayan Belt  [PDF]
Vladimir G. Trifonov, Sergey Yu. Sokolov
International Journal of Geosciences (IJG) , 2014, DOI: 10.4236/ijg.2014.55047

Tectonic uplift producing recent mountain systems has spanned in the Alpine-Himalayan Belt the time interval from Oligocene to Recent (the last 30 - 35 Ma), being divided into two stages. During the first stage, local uplands, usually not higher than middle-elevated mountains, rose and their total area increased. During the second stage (the last 5 - 2 Ma) this process was accompanied by a total uplift of the greater part of the belt. As a result, the rate of vertical movements increased, the recent mountain systems were formed, and the coarse molasses accumulated in the adjacent basins. Uplift of the land surface resulting in formation of mountain topography is an isostatic reaction to decompaction of the upper spheres of the Solid Earth. Three factors of the decompaction are discussed in the paper. These are: I, collisional compression, resulting in deformational thickening of the Earth’s crust (folding, thrusting, etc.); II, partial replacing of the lithosphere mantle by the lower-dense asthenosphere material and, as a result, decompaction of the uppermost mantle; and III, retrograde metamorphism of high-metamorphosed rocks within the lower crust and near the crust-mantle boundary and, as a result, decompaction of these rocks. These processes were initiated or facilitated by the lateral asthenosphere flows. According to the seismic tomography data, the flows spread from the stationary developed zone of the rise of deep mantle material that is expressed in the recent

Study of the Relationship between Chinese College Students’ International Posture and Their Intercultural Willingness to Communicate  [PDF]
Güliz Ulu, Fan Weiwei, Shi Yu
Chinese Studies (ChnStd) , 2015, DOI: 10.4236/chnstd.2015.43012
Abstract: This paper involves an investigation of the relationship between Chinese college students’ international posture and their intercultural willingness to communicate (IWTC) by means of questionnaires obtained from 167 Chinese college students. The results of the Pearson correlation show that there is a significant positive relationship between international posture and IWTC. In addition, the results of the multiple linear regressions indicate that Intercultural Friendship Orientation in English learning that is one factor of the international posture can significantly predict students’ IWTC.
Sensitivity of global cloud condensation nuclei concentrations to primary sulfate emission parameterizations
G. Luo ,F. Yu
Atmospheric Chemistry and Physics (ACP) & Discussions (ACPD) , 2011,
Abstract: The impact of primary sulfate emissions on cloud condensation nuclei (CCN) concentrations, one of the major uncertainties in global CCN predictions, depends on the fraction of sulfur mass emitted as primary sulfate particles (fsulfate), the fraction of primary sulfate mass distributed into the nucleation mode particles (fnucl), and the nucleation and growth processes in the ambient atmosphere. Here, we use a global size-resolved aerosol microphysics model recently developed to study how the different parameterizations of primary sulfate emission affect particle properties and CCN abundance. Different from previous studies, we use the ion-mediated nucleation scheme to simulate tropospheric particle formation. The kinetic condensation of low volatile secondary organic gas (SOG) (in addition to H2SO4 gas) on nucleated particles is calculated based on our new scheme that considers the SOG volatility changes arising from the oxidation aging. Our simulations show a compensation effect of nucleation to primary sulfate emission. We find that the change of fnucl from 5% to 15% has a more significant impact on the simulated particle number budget than that of fsulfate within the range of 2.5–5%. Based on our model configurations, an increase of fsulfate from 0% to 2.5% (with fnucl = 5%) does not improve the agreement between simulated and observed annual mean number concentrations of particles >10 nm at 21 stations but further increase of either fsulfate from 2.5% to 5% (with fnucl = 5%) or fnucl from 5% to 15% (with fsulfate = 2.5%) substantially deteriorates the agreement. For fsulfate of 2.5%–5% and fnucl of 5%, our simulations indicate that the global CCN at supersaturation of 0.2% increases by 8–11% in the boundary layer and 3–5% in the whole troposphere (compared to the case with fsulfate=0).
A numerical evaluation of global oceanic emissions of α-pinene and isoprene
G. Luo ,F. Yu
Atmospheric Chemistry and Physics (ACP) & Discussions (ACPD) , 2010,
Abstract: A numerical evaluation of global oceanic emissions of α-pinene and isoprene based on both "bottom-up" and "top-down" methods is presented. We infer that the global "bottom-up" oceanic emissions of α-pinene and isoprene are 0.013 TgC yr 1 and 0.32 TgC yr 1, respectively. By constraining global chemistry model simulations with the shipborne measurement of Organics over the Ocean Modifying Particles in both Hemispheres summer cruise, we derived the global "top-down" oceanic α-pinene source of 29.5 TgC yr 1 and isoprene source of 11.6 TgC yr 1. Both the "bottom-up" and "top-down" values are subject to large uncertainties. The incomplete understanding of the in-situ phytoplankton communities and their range of emission potentials significantly impact the estimated global "bottom-up" oceanic emissions, while the estimated total amounts of the global "top-down" oceanic sources can be influenced by emission parameterizations, model and input data spatial resolutions, boundary layer mixing processes, and the treatments of chemical reactions. The global oceanic α-pinene source and its impact on organic aerosol formation is significant based on "top-down" method, but is negligible based on "bottom-up" approach. Our research highlights the importance of carrying out further research (especially measurements) to resolve the large offset in the derived oceanic organic emission based on two different approaches.
The failure criterion based on hydrogen distribution ahead of the fatigue crack tip
Yu. G. Matvienko
Frattura ed Integrità Strutturale , 2013,
Abstract: The hydrogen effect on the fracture toughness and fatigue crack growth behaviour in the martensitic high strength steel is investigated. The secondary ion mass spectrometry method has been employed to analyse the distribution of hydrogen concentration in the zone of the crack tip and at its edges. Changes in hydrogen concentration are observed in the vicinity of the propagating crack tip and at a remote site. The hydrogen peak is reduced and moves away from the fatigue crack tip with the increase of the maximum stress intensity factor . The concept of damage evolution is used to explain fatigue crack propagation in connection with the hydrogen redistribution ahead of the crack tip. The physical failure criterion based on the hydrogen peak in the vicinity of the fatigue crack tip and the maximum stress intensity factor has been proposed. The criterion reflects changes in the hydrogen peak which resulted from the hydrogen redistribution due to the increase of the maximum stress intensity factor as the crack length increases under fatigue loading.
Infrared Thermometry in a Differential Diagnosis of the Benign and Malignant Formations of Skin
G.Yu. Kurnickov
Sovremennye Tehnologii v Medicine , 2010,
Abstract: The possibilities of the infrared thermometry use for differential diagnosis of the benign and malignant melanocytic skin formations are demonstrated, which is confirmed by clinical observations and the histological investigation results. The elaborated method of measurements is characteristic of the accomplishment simplicity and rapidity, absolute safety, sufficient accuracy, which substantially extends the physician possibilities at the patient examination and decreases a risk of diagnostic error.
Photodiode based on GaP sensitized to short-wave region of UV spectrum
Dobrovol’skii Yu. G.
Tekhnologiya i Konstruirovanie v Elektronnoi Apparature , 2012,
Abstract: An algorithm for the simulation and analysis of the parameters that determine the sensitivity of the photodiode surface-barrier structures based on n+—n-GaP—SnO2(F) has been developed. It has been shown that the monochromatic current sensitivity to radiation at wavelength of 250 nm in such a structure can reach 0,1—0,12 A/W.
On representation matrices of Kaloujnine’s 2-groups (in Russian)
Yu. G. Leonov
Matematychni Studii , 2011,
Abstract: Images of the faithful triangular representation of Kaloujnine's 2-groups are obtained.
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