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Search Results: 1 - 10 of 192651 matches for " G. Sai Krishna* "
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NAIL AS A PROMISING DRUG DELIVERY SYSTEM FOR CONTROLLED RELEASE
G. Sai Krishna*, P. Prem Kumar, K. Bala Murugan
International Journal of Pharmaceutical Sciences and Research , 2013,
Abstract: ABSTRACT: The effectiveness of topical therapies is limited by minimal drug permeability through the nail plate. Nail permeability is however quite low and limits topical therapy to early/mild disease states such as onychomycosis (fungal infections of the nail). Current research on nail permeation that focuses on altering the nail plate barrier by means of chemical treatments, penetration enhancers as well as physical and mechanical methods is reviewed also the recent research into ungual drug delivery is reviewed, a new method of nail sampling is examined. Topical therapy is worth pursuing however, as local action is required in many nail disorders. Drug transport into the nail plate can be assisted by filing the nail plate before topical application of drug formulations as well as by the use of chemical enhancers. Finally limitations of current ungual drug permeability studies are briefly discussed and the factors, which affect drug uptake and permeation through the nail plate such as solute molecular size, hydrophilicity/hydrophobicity, charge, and the nature of the vehicle, are then discussed, and drug-containing nail lacquers which, like cosmetic varnish, are brushed onto the nail plates to form a lm, and from which drug is released and penetrates into the nail are reviewed. The nail plate behaves like a concentrated hydrogel to permeating molecules and diffusion of molecules through the nail plate has been compared to the diffusion of non-electrolytes through polymer gels. Thus, for optimal ungual permeation and uptake, drug molecules must be of small size and be uncharged.
Design Of Power System Stabilizer To Improve Small Signal Stability By Using Modified Heffron-Phillip’s Model
Doradla. Prathap Hari Krishna,,G. Sai Sudheer,,B N S P. Venkatesh,,M. Tulasi
International Journal of Engineering Science and Technology , 2011,
Abstract: One of the major problems in power system operation is related to small signal instability caused by insufficient damping in the system. The most effective way of countering this instability is to use auxiliary controllers called Power System Stabilizers, to produce additional damping in the system. Generally Heffron-phillip’s Model of a synchronous machine is commonly used for the small signal stability analysis. A Modified Heffron-Phillip’s (Kconstant)Model is derived for the design of Power System Stabilizers; knowledge of external parameters, such as equivalent infinite bus voltage and external impedance value are required for designing a conventional power system stabilizer, Modified Heffron-Phillip’s Model power system stabilizer. The efficiency of the proposeddesign technique and the performance of the stabilizer has been evaluated over a range of operating and system conditions and the performance of the proposed Modified Heffron-Phillip’s Model is much better than the conventional power system stabilize.. The proposed work describes the ‘Design of Power System Stabilizer by using Modified Heffron-Phillip’s model’ is simulated by using MATLAB/SIMULINK.
FREQUENT PATTERN MINING FOR EFFICIENT LIBRARY MANAGEMENT
ANURADHA.T,SATYATEJ.K,SRI SAI KRISHNA.A,NAGA ANIL KUMAR.G
International Journal on Computer Science and Engineering , 2011,
Abstract: Data mining is used to extract meaningful information and to develop significant relationships among variables stored in large data sets involving methods from statistics and artificial intelligence butalso management. In this paper data mining technique named association technique is applied to analyze the patterns which depicts the relationship between more frequently taken books by the students. The student’s record of library data was studied based on many factors such as their subject requirements,number of books issued, and duration for each book. It is recommended that all these correlated information should be conveyed to the library department such that it helps them to improve the issue performance by avoiding the delay, maintain more number of highly required books according to the current subjects of the different streams of students.
Dynamic Voltage Restorer Based on Space Vector Pulse Width Modulation Technique
B.N S P Venkatesh,G.Sai Sudheer,D.Prathap Hari Krishna,S.Rishikesh
International Journal of Engineering Science and Technology , 2011,
Abstract: Power Quality problems encompass a wide range of disturbances such as voltage sags, swells, flicker,harmonics distortion and interruptions. The strategic deployment of custom power devices has been proposed asone of the means to protect sensitive loads from power quality problems such as voltage sags and swells. The Dynamic Voltage Restorer (DVR) is a power electronic device that is used to inject 3-phase voltage in series and in synchronism with the distribution feeder voltages in order to compensate voltage sag and similarly itreacts quickly to inject the appropriate voltage component (negative voltage magnitude) in order to compensate voltage swell. The principal component of the DVR is a voltage source inverter that generates three phase voltages and provides the voltage support to a sensitive load during voltage sags and swells. Pulse Width Modulation Technique is very critical for proper control of DVR. Sinusoidal Pulse Width Modulation (SPWM) and Space Vector Pulse Width Modulation (SVPWM) control techniques are used for controlling the DVR. Inthis work, the operation of DVR is presented and the control technique used for voltage source inverter is Space Vector PWM technique. Space vector PWM can utilize the better dc voltage and generates the fewer harmonic in inverter output voltage than Sinusoidal PWM technique. This work describes the DVR based on Space Vector PWM which provides voltage support to sensitive loads and is simulated by using MATLAB/SIMULINK. Simulation results show that the control approach is able to compensate for any type of voltage sags and swells.
On unavoidable obstructions in Gaussian walks
Sai Teja Somu,Ram Krishna Pandey
Mathematics , 2015,
Abstract: In this paper we investigate a problem about certain walks in the ring of Gaussian integers. Let $n,d$ be two natural numbers. Does there exist a sequence of Gaussian integers $z_j$ such that $|z_{j+1}-z_j|=1$ and a pair of indices $r$ and $s$, such that $z_{r}-z_{s}=n$ and for all indices $t$ and $u$, $z_{t}-z_{u}\neq d$? If there exists such a sequence we call $n$ to be $d$ avoidable. Let $A_n$ be the set of all $d\in \mathbb{N}$ such that $n$ is not $d$ avoidable. Recently, Ledoan and Zaharescu proved that $\{d \in \mathbb{N} : d|n\}\subset A_n$. We extend this result by giving a necessary and sufficient condition for $d\in A_n$ which answers a question posed by Ledoan and Zaharescu. We also find a precise formula for the cardinality of $A_n$ and answer three other questions raised in the same paper.
Application Denial of Service Attacks Detection using Group Testing Based Approach
P.Ravi Kiran Varma,D.Sai Krishna
International Journal of Computer Science and Communication Networks , 2012,
Abstract: In this paper we explore the mechanisms for detecting the application dos attacks which is a new class of Dos attack. It aims at disrupting the application service rather than depleting the network services. These possess severe threat to Internet Security. Detection and prevention of these attacks are harder compared to classic dos attacks. These attacks have high similarity with legitimate traffic so tracing the attack origin is more difficult. We proposed a new novel Group testing which provide short detection delay and low false positive/negative rate. We propose a two mode detection mechanism using some dynamic threshold for identifying the attackers efficiently.
Safekeeping of Network Executive for a Domestic Internet Service Provider
K.V.N.R. Sai Krishna
International Journal of Computer Science and Mobile Computing , 2013,
Abstract: A net is one of the most important basic resources a large institution needs to have. Today, anetwork plays a very important role in every group. With extensive dispersed positioning, supervision thesecurity of a network becomes very complex especially from the viewpoint of an ISP. ISP's are by naturallymore susceptible because they have to offer a multitude of public amenities both for their customers and onbehalf of them. Actual Net and Safety supervision needs to be executed taking into Consideration the lack ofbandwidth and availability of computing resources at the nodes. Safety supervision now productions a largerrole as all communication is over the insecure Internet. In this paper, the various issues involved indeveloping a Safety Supervision System for a low bandwidth system is discussed. Then, a solution executedbased on open Standards for a national ISP aiming on countryside zones.
Significance of Maximum Spectral Amplitude in Sub-bands for Spectral Envelope Estimation and Its Application to Statistical Parametric Speech Synthesis
Sivanand Achanta,Anandaswarup Vadapalli,Sai Krishna R.,Suryakanth V. Gangashetty
Computer Science , 2015,
Abstract: In this paper we propose a technique for spectral envelope estimation using maximum values in the sub-bands of Fourier magnitude spectrum (MSASB). Most other methods in the literature parametrize spectral envelope in cepstral domain such as Mel-generalized cepstrum etc. Such cepstral domain representations, although compact, are not readily interpretable. This difficulty is overcome by our method which parametrizes in the spectral domain itself. In our experiments, spectral envelope estimated using MSASB method was incorporated in the STRAIGHT vocoder. Both objective and subjective results of analysis-by-synthesis indicate that the proposed method is comparable to STRAIGHT. We also evaluate the effectiveness of the proposed parametrization in a statistical parametric speech synthesis framework using deep neural networks.
Fiber Bragg grating and long period grating sensor for simultaneous measurement and discrimination of strain and temperature effects
Kamineni Srimannarayana,Madhuvarasu Sai Shankar,Ravinuthala L.N. Sai Prasad,T.K. Krishna Mohan
Optica Applicata , 2008,
Abstract: Fiber Bragg grating sensors are novel in the determination of various physical parameters. In the case of fiber Bragg grating, on a single measurement of wavelength shift, it is impossible to differentiate between the effects of changes in strain and temperature. The simulation of fiber Bragg grating, long period grating characteristics and use of the different strain-temperature response of combined sensor for the simultaneous measurement and discrimination of strain and temperature in C band are demonstrated.
Modified Newton's rings: II
T. Sai Chaitanya,Rajiv kumar,V. Sai Krishna,B Shankar Anandh,K. S. Umesh
Physics , 2010,
Abstract: In an earlier work (Shankar kumar Jha, A Vyas, O S K S Sastri, Rajkumar Jain & K S Umesh, 'Determination of wavelength of laser light using Modified Newton's rings setup', Physics Education, vol. 22, no.3, 195-202(2005)) reported by our group, a version of Newton's rings experiment called Modified Newton's rings was proposed. The present work is an extension of this work. Here, a general formula for wavelength has been derived, applicable for a plane of observation at any distance. A relation between the focal length and the radius curvature is also derived for a plano-convex lens which is essentially used as a concave mirror. Tracker, a video analysis software, freely downloadable from the net, is employed to analyze the fringes captured using a CCD camera. Two beams which give rise to interference fringes in conventional Newton's rings and in the present setup are clearly distinguished.
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