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Search Results: 1 - 10 of 463470 matches for " G. S. Bilaspuri "
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Impacts of Oxidative Stress and Antioxidants on Semen Functions
Amrit Kaur Bansal,G. S. Bilaspuri
Veterinary Medicine International , 2011, DOI: 10.4061/2011/686137
Abstract: Oxidative stress (OS) has been considered a major contributory factor to the infertility. Oxidative stress is the result of imbalance between the reactive oxygen species (ROS) and antioxidants in the body which can lead to sperm damage, deformity, and eventually male infertility. Although high concentrations of the ROS cause sperm pathology (ATP depletion) leading to insufficient axonemal phosphorylation, lipid peroxidation, and loss of motility and viability but, many evidences demonstrate that low and controlled concentrations of these ROS play an important role in sperm physiological processes such as capacitation, acrosome reaction, and signaling processes to ensure fertilization. The supplementation of a cryopreservation extender with antioxidant has been shown to provide a cryoprotective effect on mammalian sperm quality. This paper reviews the impacts of oxidative stress and reactive oxygen species on spermatozoa functions, causes of ROS generation, and antioxidative strategies to reduce OS. In addition, we also highlight the emerging concept of utilizing OS as a tool of contraception. 1. Introduction Gametes are susceptible to reactive oxygen species (ROS) attack. When manipulated in vitro during assisted reproductive techniques, these cells run the risk of generating and being exposed to supra-physiological level of ROS [1]. Defective sperm functions are the most prevalent causes of male infertility and a difficult condition to treat [2]. Many environmental, physiological, and genetic factors have been implicated in the poor sperm functions and infertility [3–6]. Thus, it is very important to identify the factors/conditions which affect normal sperm functions. Among various causes, oxidative stress (OS) has been attributed to affect the fertility status and physiology of spermatozoa [7]. The term oxidative stress is generally applied when oxidants outnumber antioxidants [1]. The imbalance between the production of reactive oxygen species (ROS) and a biological systems ability to readily detoxify the reactive intermediates or easily repair the resulting damage is known as oxidative stress [8]. The main destructive aspects of oxidative stress are the production of ROS, which include free radicals and peroxides [9]. The production of ROS by sperm is a normal physiological process, but an imbalance between ROS generation and scavenging activity is detrimental to the sperm and associated with male infertility [10]. Physiological levels of ROS influence and mediate the gametes [11–13] and crucial reproductive processes, such as sperm-oocyte
Manganese Provides Antioxidant Protection for Sperm Cryopreservation that May Offer New Consideration for Clinical Fertility
Ranjna S. Cheema,Amrit K. Bansal,Gurmail Singh Bilaspuri
Oxidative Medicine and Cellular Longevity , 2009, DOI: 10.4161/oxim.2.3.8804
Abstract: Reactive oxygen species (ROS) are generated by sperm metabolism. While, ROS are required for maturation, capacitation and acrosome reaction, they also modify many peroxidable cellular compounds. There is production of ROS during cryopreservation and frozen spermatozoa are highly sensitive to lipid peroxidation (LPO). Antioxidants exert a protective effect on the plasma membrane of frozen bovine sperm preserving both metabolic activity and cellular viability. Manganese (Mn
Ground State of 4-7H Considering Internal Collective Rotation  [PDF]
S. Paschalis, G. S. Anagnostatos
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.45B012

The g.s. of heavy and superheavy hydrogen isotopes, namely 4-7 H, are successfully examined by applying the Isomorphic Shell Model. Properties examined are binding energies and effective radii. The novelty of the present work is that, due to the small number of nucleons involved and the subsequently large deformation, an internal collective rotation appears which is inseparable from the usual internal motion even in the ground states of these nuclei, i.e., for such nuclei the adiabatic approximation is not valid. This extra degree of freedom leads to a reduction of binding energies, an increase of effective radii, and an increase of level widths.

Reliability Optimization of Entropy Based Series-Parallel System Using Global Criterion Method  [PDF]
Intelligent Information Management (IIM) , 2009, DOI: 10.4236/iim.2009.13021
Abstract: In this paper, we have considered a series-parallel system to find out optimum system reliability with an additional entropy objective function. Maximum system reliability of series-parallel system is depending on proper allocation of redundancy component in different stage. The goal of entropy based reliability redundancy allocation problem is to find optimal number of redundancy component in each stage such a manner that maximize the system reliability subject to available total system cost. Global criterion method is used to analyze entropy based reliability optimization problem with different weight function of objective functions. Numerical examples have been provided to illustrate the model.
Quantum Isomorphic Shell Model: Multi-Harmonic Shell Clustering of Nuclei  [PDF]
G. S. Anagnostatos
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.45B011
Abstract: The present multi-harmonic shell clustering of a nucleus is a direct consequence of the fermionic nature of nucleons and their average sizes. The most probable form and the average size for each proton or neutron shell are here presented by a specific equilibrium polyhedron of definite size. All such polyhedral shells are closely packed leading to a shell clustering of a nucleus. A harmonic oscillator potential is employed for each shell. All magic and semi-magic numbers, g.s. single particle and total binding energies, proton, neutron and mass radii of 40Ca, 48Ca, 54Fe, 90Zr, 108Sn, 114Te, 142Nd, and 208Pb are very successfully predicted.


Polyhedral symmetry and quantum mechanics  [PDF]
G. S. Anagnostatos
Natural Science (NS) , 2014, DOI: 10.4236/ns.2014.64024

A thorough study of regular and quasi-regular polyhedra shows that the symmetries of these polyhedra identically describe the quantization of orbital angular momentum, of spin, and of total angular momentum, a fact which permits one to assign quantum states at the vertices of these polyhedra assumed as the average particle positions. Furthermore, if the particles are fermions, their wave function is anti-symmetric and its maxima are identically the same as those of repulsive particles, e.g., on a sphere like the spherical shape of closed shells, which implies equilibrium of these particles having average positions at the aforementioned maxima. Such equilibria on a sphere are solely satisfied at the vertices of regular and quasi-regular polyhedra which can be associated with the most probable forms of shells both in Nuclear Physics and in Atomic Cluster Physics when the constituent atoms possess half integer spins. If the average sizes of the constituent particles are known, then the average sizes of the resulting shells become known as well. This association of Symmetry with Quantum Mechanics leads to many applications and excellent results.

Teacher Candidates’ (Pedagogical Formation Students’) Communication Skills  [PDF]
Süleyman G?ksoy
Creative Education (CE) , 2014, DOI: 10.4236/ce.2014.514152

The purpose of this study is to identify pedagogical formation students’ (teacher candidates’) communication skills based on their perceptions. The study sought answers to the following research question: What are the perceptions of pedagogical formation students (teacher candidates) related to their communication skills? Assessment of pedagogical formation students’ (teacher candidates’) perceptions regarding their communication skills was undertaken through qualitative research methods. Qualitative data collected with the help of semi-structured interview form were analyzed in terms of content. The study was conducted with the participation of 48 teacher candidates attending pedagogical formation classes at Düzce University during 2013-2014 academic year. According to the data obtained at the end of the study, teacher candidates are aware of the necessity and importance of communication. They are aware that the prerequisite for being contented, successful and social individuals and professionals is healthy and good communication with others. Teacher candidates know the importance and necessity of body language in effective communication and generally prefer to use it. They are also aware of the need for written and oral communication when required. Psychological situations such as anxiety, stress, lack of self-efficacy, timidity, fear and excitement are regarded as barriers that inhibit communication. These barriers are followed by being misunderstood, lack of feedback and language, culture, prior information and prejudices related to inappropriate context/environment and persons involved in communication. Teacher candidates express that they can develop communication skills by participating in social activities. They also state that they can develop communication skills by reading books/articles/research findings, participating in courses/seminars/conferences, meeting new and different people and taking training-expert support.

Air-Water Cooling System for Switch-Mode Power Supplies  [PDF]
G. Casano, S. Piva
Journal of Electronics Cooling and Thermal Control (JECTC) , 2015, DOI: 10.4236/jectc.2015.53005
Abstract: The results are presented of an experimental investigation of heat transfer in an air-liquid cooling system for a Switch-Mode Power Supply (SMPS) for TV digital power amplifiers. Since these SMPSs are characterized by high power and high compactness, thereby making the standard cooling techniques difficult to be used, a new cooling system is developed, using water and air as the cooling media. The active components (MOSFETs) are cooled with a liquid cold-plate, the passive ones (condensers, transformers, coils) with an air flow, in turn cooled by the cold-plate. By inserting the cooling system in an experimental tool where it is possible to control the cooling water, measurements are made of temperature in the significant points of the SMPS. The electric efficiency is also measured. The evaluation of the thermal performance of this cooling system is useful in order to limit its maximum operational temperature. The efficacy of the cooling system is demonstrated; the trends of efficiency and power dissipation are evidenced.
Variability in Surgical Quality among Surgeons in Breast Cancer Surgery  [PDF]
S. G. D. Gangadaran
Advances in Breast Cancer Research (ABCR) , 2016, DOI: 10.4236/abcr.2016.54015
Abstract: Introduction: Quality assurance is an essential aspect of cancer care. Assessment of surgical quality in breast cancer is still evolving. Variability in surgical care among surgeons has been well documented in literature and we sought to investigate such variation between two groups of surgeons referring patients to our oncology center. Methods: A prospective review of patient records of all breast cancer referrals to our department was made. Two groups were identified and segregated based on the performance of mastectomy by a general surgeon (GS) or by a surgical oncologist (SO). Patients treated with modified radical mastectomy for clinical stages 1 - 3 were included for the study. Patient demographic data and disease related information were collected in addition to thorough evaluation of the surgical pathology report. Margin positivity, mean nodal harvest, nodal ratio, inadequate axillary clearance, revision surgery and the use of radiotherapy for inadequate nodal dissection were the parameters evaluated in the study. Results: A total of 142 patient records were evaluated 72 designated as group 1 (general surgeons) and 70 as group 2 (surgical oncologist). The median age was 52 years and both groups were evenly balanced for age, laterality of breast lesion, histological type and grade. The mean nodal harvest was 8 vs. 14 nodes, and significant differences were observed in favor of surgical oncology group in margin positivity (P = 0.01), inadequate axillary clearance (P
Pre-School Educational Process of Turkey  [PDF]
Süleyman G?ksoy
Open Journal of Social Sciences (JSS) , 2017, DOI: 10.4236/jss.2017.53008
Abstract: Children make a rapid development physically, cognitively and affectively in preschool educational period (age 0 - 6). The cognitive dimension of a child at pre-school age is creative, independent and imaginary. The imagination unceasingly works. This period is regarded as the time that the children have high potential of learning and developing. Thus, the quality of preschool education affects the higher educational success and even the lifelong success of the child. Therefore the aims of the research are to emphasize the importance of preschool education on the development of the child, to make a comparison between the preschool education of Turkey and other developed countries and to support preschool education by explaining why and how the preschool education in Turkey should be improved. In this research, case study method from data collection methods was used; related written and electronic resources were collected, analyzed and interpreted in line with the research purpose. The following suggestions are developed in order to improve the preschool education in Turkey: Service delivery models that increase the participation to preschool education should be varied; the preschool educational facilities should be extended supporting the access of regions with limited financial means and regulations that decreasing the educational costs of families should be adopted. For all children, especially for families with low income, preschool educational institutions should be free like in more than half of European Union countries or preschool educational costs should be arranged in accordance with family incomes and other criterion, and families should be supported. The improvement and development priority should be given to preschool educational stage, accordingly physical resources (building, materials, substructure) and human resources (manager, educator, deputy manager and support staff) should be provided. Besides preschool teaching departments should be opened in faculties of education in universities and the quota of preschool teaching departments should be increased.
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