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Search Results: 1 - 10 of 197503 matches for " G. Bruno "
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World Trade Logics and Measure of Global Inequality: Regional Pattern and Globalization Evolution between 2003-2012  [PDF]
Bruno G. Rüttimann
Open Journal of Applied Sciences (OJAppS) , 2014, DOI: 10.4236/ojapps.2014.44019
Abstract: The economy is globalizing. But how are the different economic world regions performing regarding globalization of trade flows? Why are they performing differently? Globalization is not only the increase of international trade between certain preferential geographic areas of economy, but also the resulting increase of interweavement of trade flows between different geographical areas, independent of the amount of trade. This paper is a revised and expanded version of the paper entitled “World Trade and Associated Systems Risk of Global Inequality: Empiric Study of Globalization Evolution between 2003-2011 and Regional Pattern Analysis” presented at International Conference on Applied Economics (ICOAE2013), Istanbul, 27-29 June, 2013. This paper analyzes the evolution of world trade flows between 2003-2012 and performs a cross-section analysis of the year 2012. The economic interweavement will be measured by an inequality risk metric applied to the supply-demand matrix. This risk indicator is based on the concept of statistical entropy resulting in an inequality risk measure, giving an indication for the degree of economic globalization and the evolution of globalization in different geographical regions. In addition, it analyses the governing rational of globalization evolution. The result of this research shows that economic trade flows are globalizing, but with clear different regional patterns, not only between globalizing and de-globalizing regions, but also within the globalizing and de-globalizing regions itself. The emerging economies such as China or the Middle East are globalizing whereas mature economies such as North America and Europe are de-globalizing, confirming for globalization of the inverse Kuznets evolution. The different patterns between the different economic world regions can be explained by using the Globalization Type’s Model as well as the Central Theorem of Globalization.
Discourse about Linear Programming and Lean Manufacturing: Two Different Approaches with a Similar, Converging Rational  [PDF]
Bruno G. Rüttimann
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.81010
Abstract: In recent years, the Toyota Production System has also assumed in western manufacturing plants a predominant position. Lean Manufacturing, as it is usually called in the occidental world, aims at a “Single-piece-flow” job handling and has its advantages compared to the classic “Batch and Queue” job handling. On the other hand, mathematical Linear Programming optimization techniques have passed into oblivion, having obtained the feel to be inappropriate for production planning. Although the two approaches have different aims and application, they give particular attention to scarce resources. The concepts of “bottleneck” in Lean Manufacturing and “shadow price” in Linear Programming are complementary. The paper shows the different focus of the two approaches and crystallizes their synergic values.
Light output response of the LVD liquid scintillator to neutron-induced nuclear recoils
G. Bruno
Physics , 2013, DOI: 10.1088/1748-0221/8/05/T05004
Abstract: The organic liquid scintillator used in the LVD experiment (INFN Gran Sasso National Laboratory) has been exposed to an Am-Be neutron source to measure the light response function for neutron energies in the region from about 4 to 11 MeV. A full Monte Carlo simulation, incorporating the detector response, is used to generate neutron scattering spectra which are matched to the observed ones to determine the quenching factors. The obtained light output response is well described by the semi-empirical Birks model. The results, consistent with those obtained by other authors using similar hydrocarbonate scintillators, can be of interest for fast and high-energy neutron spectroscopy that could be performed with this detector.
The Power of DOE: How to Increase Experimental Design Success and Avoid Pitfalls  [PDF]
Bruno G. Rüttimann, Konrad Wegener
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.82028
Abstract: Personal empirical experience when lecturing and consulting shows that not only students, but also experienced engineers familiar with DOE, show much more interest in the modeling of a process than to statistical inference, neglecting attention to “boundary conditions” of the process. But exactly the observation of ancillary boundary conditions of experiments, such as minimizing Beta-risk and noise, is determinant for the efficient execution of an experimental design and the effective application of DOE derived models. This essay focuses attention to the must-dos in the DOE statistics approach in order to avoid research pitfalls by presenting a fail-proof 14-step approach when applying DOE modeling.
Etimología y Fonética Neohelénica del vocabulario médico: Autoaprendizaje mediante la práctica Diccionario Griego-Espa ol según la ortografía monotónica de 1982
Bruno Günther S
Revista médica de Chile , 2003,
Rese a de "Marcha de Montevideo y la formación de la conciencia latinoamericana a través de sus cuadernos" de Luisa Peirano Basso
Paula G. Bruno
Araucaria , 2003,
A Review of Therapeutic Aptamer Conjugates with Emphasis on New Approaches
John G. Bruno
Pharmaceuticals , 2013, DOI: 10.3390/ph6030340
Abstract: The potential to emulate or enhance antibodies with nucleic acid aptamers while lowering costs has prompted development of new aptamer-protein, siRNA, drug, and nanoparticle conjugates. Specific focal points of this review discuss DNA aptamers covalently bound at their 3' ends to various proteins for enhanced stability and greater pharmacokinetic lifetimes in vivo. The proteins can include Fc tails of IgG for opsonization, and the first component of complement (C1q) to trigger complement-mediated lysis of antibiotic-resistant Gram negative bacteria, cancer cells and possibly some parasites during vulnerable stages. In addition, the 3' protein adduct may be a biotoxin, enzyme, or may simply be human serum albumin (HSA) or a drug known to bind HSA, thereby retarding kidney and other organ clearance and inhibiting serum exonucleases. In this review, the author summarizes existing therapeutic aptamer conjugate categories and describes his patented concept for PCR-based amplification of double-stranded aptamers followed by covalent attachment of proteins or other agents to the chemically vulnerable overhanging 3' adenine added by Taq polymerase. PCR amplification of aptamers could dramatically lower the current $2,000/gram cost of parallel chemical oligonucleotide synthesis, thereby enabling mass production of aptamer-3'-protein or drug conjugates to better compete against expensive humanized monoclonal antibodies.
Magnetic Anistropy due to the Casimir Effect
G. Metalidis,P. Bruno
Physics , 2009, DOI: 10.1103/PhysRevA.81.022123
Abstract: We consider the Casimir interaction between a ferromagnetic and a non-magnetic mirror, and show how the Casimir effect gives rise to a magnetic anisotropy in the ferromagnetic layer. The anisotropy is out-of-plane if the non-magnetic plate is optically isotropic. If the non-magnetic plate shows a uniaxial optical anisotropy (with optical axis in the plate plane), we find an in-plane magnetic anisotropy. In both cases, the energetically most favorable magnetization orientation is given by the competition between polar, longitudinal and transverse contributions to the magneto-optical Kerr effect, and will therefore depend on the interplate distance. Numerical results will be presented for a magnetic plate made out of iron, and non-magnetic plates of gold (optically isotropic), quartz, calcite and barium titanate (all uniaxially birefringent).
Brief physics survey with CMS in year one
G. Bruno,for the CMS Collaboration
Physics , 2003,
Abstract: The CMS detector is one of the two general purpose experiments that will study the collisions produced by the Large Hadron Collider (LHC). The LHC is supposed to start its operation in 2007 at an instantaneous luminosity of 2 x 10^33 cm-2 s-1, which may well result in an integrated luminosity of 10 fb-1 after the first year of running. The corresponding physics reach of CMS is exemplified with the study of a few standard model channels (weak boson and top quark production) and with the searches for Higgs bosons.
Inelastic scattering effects and the Hall resistance in a 4-probe ring
G. Metalidis P. Bruno
Physics , 2005, DOI: 10.1103/PhysRevB.73.113308
Abstract: Phase randomizing processes in mesoscopic systems can be described in a phenomenological way within the Landauer-B\"{u}ttiker formalism by attaching extra voltage probes to the sample. In this paper, it is shown that a perturbation treatment of this idea allows for the incorporation of such effects without the need of giving up the efficiency of recursive techniques commonly used for calculating the transmission coefficients. The technique is applied to a 4-probe ring, where a Hall effect can be observed that originates from quantum interference rather than a Lorentz force acting on the electrons. The influence of inelastic scattering on both the Hall resistance and the Aharonov-Bohm oscillations in the longitudinal resistance are examined.
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