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匹配条件: “Gómez” ,找到相关结果约189829条。
Into the life and death: RecA a WISE factor working to integrate survival and evolution in Escherichia coli  [PDF]
José María Gómez Gómez
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.43A059

Escherichia coli RecA has been considered traditionally a cellular protein with multiple vital functions working to ensure the maintenance of integrity of genome in each individual bacterial cell as well as promoting swarming migration in collectivity. On the contrary, recently it has been described that RecA promotes cellular apoptotic-like death (ALD), a pathway of programmed cellular death (PCD). In fact, RecA has been dubbed as the major apoptotic executor in E. coli. From these studies, RecA emerges as a prototypical Gin/Gan protein that despite of their intrinsic vital and lethal anfi-funcionality becomes in a WISE factor: a Worker to Integrate Survival and Evolution in E. coli evolving populations living in community. Here, I provide a review of recent experimental and conceptual advances trying to understand these RecA’s antagonistic roles in appearance contradictory under a unified biological vision.

Equilibrium Dynamics in the Neoclassical Growth Model with Habit Formation and Elastic Labor Supply  [PDF]
Manuel A. Gómez
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.25087
Abstract: This note analyzes the equilibrium dynamics in the neoclassical growth model with habit-forming preferences and elastic labor supply. Habits enter into utility in a multiplicative way. The specification of the habit formation process comprises the particular cases of internal and external habits. Existence, uniqueness and saddle-path stability of the steady state are proved analytically.
A Novel Cellular Autoaggregative Developmentally CRP Regulated Behaviour Generates Massively Chondrule-Like Formations over Surface of Old Escherichia coli K-12 Macrocolony Biofilms  [PDF]
José María Gómez Gómez, Ricardo Amils
Advances in Bioscience and Biotechnology (ABB) , 2014, DOI: 10.4236/abb.2014.59086

How Escherichia coli bacteria develop a particular colonial, 3-D biofilm morphological pattern is still a poorly understood process. Recently, we reported a new E. coli K-12 morphotype exhibited by old macrocolonies described as volcano-like. The formative developmental process of this morphotype has been presented as a suitable experimental model for the study of 3D patterning in macrocolony biofilms. Here, we report the optical microscopy observations and genetic analysis that have unveiled the existence of a novel autoaggregative behaviour which generates massive lumpiness over the surface of the volcano-like macrocolonies. These lumpy formations are generated by the autoaggregation and strong interaction of tightly packed bacterial cells in structures with a chondrule-like appearance which give the colony’s surface its characteristic microscopic lumpy phenotype. Furthermore, they exhibit different levels of maturation from the edge to the center of the colony. Hence, its generation appears to follow a spatiotemporal program of development during the macrocolony’s morphogenesis. Interestingly, the agar’s hardness influences the morphology exhibited by these formations, with high agar concentration (1.5%, 15 g/L) suppressing its development. This new auto-aggregative E. coli’s behaviour does not require the activity of the biofilm master regulator CsgD, the adhesiveness of flagella, pili type 1, adhesin Ag43, β-1,6-N-acetyl-D-glucosamine polymer-PGA, cellulose or colanic acid, but it is under glucose repression and the control of cAMP receptor protein (CRP). The possible physiological role

Relevance of Epistemological Pluralism for Resource Management Policies  [PDF]
Mónica Gómez Salazar
Open Journal of Philosophy (OJPP) , 2015, DOI: 10.4236/ojpp.2015.56039
Abstract: The common believe of a single successful form of knowing the reality is misleading. A brief analysis of many human activities reveals a pluralistic perspective of several coexisting conceptual schemes that underlie the form in which women and men know and constitute the world in which we live. Here, I will discuss the necessity of taking seriously this pluralistic perspective when developing conceptual frameworks of human activities. As an example of great interest and importance, I will consider the case of resource management that has to contemplate the conservation and the response of ecosystems to human activities that may lead to irreversible damage. Ecosystems’ activity occurs over a wide range of space and time scales and, hence, policies and proposals of solutions to ecological problems should avoid narrow and monochromatic approaches. Specifically, the Pemon perspective of fire is a good example to show that for more robust and flexible resource management we need the knowledge and experience of different cultural and disciplinary groups.
Estudios Gerenciales , 2001,
Abstract: el objetivo de la mayoría de las compa?ías se centra en obtener el liderazgo de su respectivo mercado, desarrollando diferentes estrategias, las cuales buscan ganar la preferencia del cliente en el momento de seleccionar una marca. como variable crítica para lograrlo se encuentra la generación de una ventaja competitiva que lo diferencie de sus competidores. sin embargo, la construcción de una ventaja competitiva es un proceso complejo que parte de la identificación de las necesidades del mercado. es decir, sólo se obtendrá una ventaja competitiva si la empresa conoce realmente cuáles son los aspectos a los que el mercado les asigna valor, logrando satisfacerlos mejor que la competencia y de manera sostenible. el presente artículo se centra en la metodología para identificar esas variables críticas en la decisión de compra en los mercados industriales, las cuales permitirán a la organización ajustar su estrategia para lograr la preferencia de compra. aunque se centra en la industria de materiales autoadhesivos, la aplicación de esta metodología y su marco de referencia se ajustan a cualquier mercado de tipo industrial, donde las decisiones son tomadas por grupos de compras multidisciplinarios y tienen una mayor complejidad técnica que las decisiones en los segmentos de productos de consumo masivo.
Equidad, género y salud: retos para la acción
Gómez Gómez,Elsa;
Revista Panamericana de Salud Pública , 2002, DOI: 10.1590/S1020-49892002000500024
Abstract: the governing bodies of the pan american health organization (paho) have mandated that the organization apply a gender perspective in all aspects of the organization's activities and its technical cooperation in the area of health with the paho member states. this article points out the need to eradicate unjust gender differences that affect the right and access to health care that is appropriate for women. the piece explains the differences between equity and equality and between gender and sex, and how gender equity should come about in the state of health, in health care, and in all people's efforts to engender health. it is hoped the piece will contribute to a better understanding of the situation, thus helping to eliminate inequities that are due to sex, socioeconomic factors, and the distribution of power.
Equidad de género en las políticas de reforma del sector de la salud de América Latina y el Caribe
Gómez Gómez,Elsa;
Revista Panamericana de Salud Pública , 2002, DOI: 10.1590/S1020-49892002000500020
Abstract: gender equity is increasingly being acknowledged as an essential aspect of sustainable development and more specifically, of health development. the pan american health organization's program for women, health, and development has been piloting for a year now a project known as equidad de género en las políticas de reforma del sector de salud, whose objective is to promote gender equity in the health sector reform efforts in the region. the first stage of the project is being conducted in chile and peru, along with some activities throughout the region. the core of the project is the production and use of information as a tool for introducing changes geared toward achieving greater gender equity in health, particularly in connection with male-female disparities that are unnecessary, avoidable, and unfair in health status, access to health care, and participation in decision-making within the health system. we expect that in three years the project will have brought about changes in the production of information and knowledge, advocacy, and information dissemination, as well as in the development, appropriation, and identification of intersectoral mechanisms that will make it possible for key figures in government and civil society to work together in setting and surveying policy on gender equity in health.
Género, equidad y acceso a los servicios de salud: una aproximación empírica
Gómez Gómez,Elsa;
Revista Panamericana de Salud Pública , 2002, DOI: 10.1590/S1020-49892002000500008
Abstract: this piece describes the conceptual framework and the objectives that guided a research initiative in the region of the americas that was called "gender, equity, and access to health services" and that was sponsored in 2001 by the pan american health organization. the piece does not summarize the results of the six projects that were carried under the initiative, whose analyses have not all been completed. instead, the piece discusses some of the foundations of the initiative and provides a general introduction to the country studies that were done. the six studies were done in barbados/jamaica, brazil, chile, colombia, ecuador, and peru. the primary objective of the initiative was to stimulate the use of existing quantitative information in the countries, with the goal of starting a process of systematically documenting two things: 1) the unfair, unnecessary, and avoidable inequalities between men and women in their access to health care and 2) the linkages between those inequalities and other socioeconomic factors. the concept of gender equity that guided this examination of health care was not the usual one calling for the equal distribution of resources. rather, it was the notion that resources should be allocated differentially, according to the particular needs of men and of women, and that persons should pay for health services according to their economic ability rather than their risk level. the starting point for the initiative was the premise that gender inequities in utilizing and paying for health care result from gender differences in the macroeconomic and microeconomic distribution of resources. the piece concludes that achieving equity in health care access will require a better understanding of the gender needs and gender barriers that are linked to social structures and health systems.
Secretarios y escribanos en el gobierno de las Indias: El caso de Juan de Sámano
Gómez Gómez,Margarita;
Revista de historia del derecho , 2012,
Abstract: juan de sámano, notary and secretary of the council of the indies under charles i, got from the king the monopoly on escribanías mayores de gobierno and audiencias y chancillerías (royal audiencia). this study discusses how he got this privilege and the importance that his family and his professional circumstances had in this concession. the aim is to deepen the know ledge of the offices of the pen and their documentary practices, and also in their types and variants, as well as the strategies and power that some of them generated.
Competencias profesionales en trabajo social Professional Competences in Social Work
Francisco Gómez Gómez
Portularia : Revista de Trabajo Social , 2010, DOI: 10.5218/prts.2010.0016
Abstract: Los temas más importantes recogidos, entre otros, en los libros blancos de las titulaciones universitarias de grado, publicados por la Agencia Nacional de Evaluación de la Calidad y Acreditación (ANECA) son los relativos a las competencias profesionales. Por ello, los estudios para la adquisición y desarrollo de esas competencias resultan de gran utilidad para proceso iniciado con la Convergencia Europea Universitaria.Los resultados presentados se obtuvieron mediante la aplicación de un cuestionario dise ado con las competencias profesionales más importantes recogidas en el Libro Blanco de la Titulación de Grado en Trabajo Social. El objetivo metodológico fundamental pretendido fue aplicar algunas nociones básicas de la lógica difusa en el tratamiento informático de los datos del cuestionario, lo que metodológicamente supone cambios importantes en la influencia que ejerce la incertidumbre en su tratamiento, si se la compara con el tratamiento informático clásico de los cuestionarios de investigación.La participación activa de los estudiantes en su aprendizaje influye de forma positiva en la adquisición de compentencias profesionales, lo que supone considerar y utilizar la incertidumbre como una base fundamental de aprendizaje para crear nuevas formas y maneras de actuar e intervenir en la realidad de cada profesional. One of the most important items collected by the White Papers of university qualifications of degree -published by the National Agency for Quality Assessment and Accreditation (ANECA)- are professional's skills.The results presented in this paper were obtained through the applying of a questionnaire made with the most important professional's skills, which are proposed by the White Paper of the Graduate Degree in Social Work.The main methodological aim was to apply some basic concepts on fuzzy logic through the processing of the research questionnaires. This means, methodically, very important changes in the influence of the uncertainty within the processing data when it is compared with the classic computer processing of the research questionnaires.The aim of our study (acquiring skills) leads to reflection and discussion about some significant findings in the monitoring of our main hypothesis: the active participation of the students in their own learning process has as a result a positive influence in acquiring professional skills. This, necessarily, involves considering and using the uncertainty as a fundamental basis to develop new ways to act and perform in the reality of each professional.

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