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Search Results: 1 - 10 of 108194 matches for " Fu Sheng Liu "
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QGP formation time and direct photons from heavy ion collisions
Fu-Ming Liu,Sheng-Xu Liu
Physics , 2012, DOI: 10.1103/PhysRevC.89.034906
Abstract: We investigated the information carried by the data of direct photons, ie, the transverse momentum spectrum and the elliptic flow $v_{2}$ from Pb+Pb collisions at $\sqrt{s_{NN}}$=2.76TeV measured at Large Hadron Collider (LHC) and from Au+Au collisions at $\sqrt{s_{NN}}$= 200 GeV measured at Relativistic Heavy Ion Collider (RHIC), in the frame work of (3+1)-dimensional ideal hydrodynamical models constrained with hadronic data. We found those direct photon data may serve as a useful clock at the early stage of heavy ion collisions. The time scales of reaching thermal and chemical equilibrium, extracted from those data, are about 1/3 and 1.5 fm/c, respectively. Thus the large elliptic flow of direct photons is explainable. High order harmonics, ie, $v_3$, $v_4$ and $v_5$, of direct photons from Pb+Pb collisions at 2.76TeV are also predicted, as a further test to compete with those who claim new sources of photons to account for the large elliptic flow of direct photons.
Minimum Amounts of Extracting Solvent of (A1A2···At-1)/(A2A3···At) Countercurrent Extraction Separation  [PDF]
Fu-Xiang Cheng, Sheng Wu, Song-Ling Wang, Bo Zhang, Yan Liu, Chun-Sheng Liao, Chun-Hua Yan
Advances in Materials Physics and Chemistry (AMPC) , 2015, DOI: 10.4236/ampc.2015.58032
Abstract: Minimum amounts of extracting solvent and scrubbing agent solution (denoted as Smin and Wmin respectively) mean the theoretical minimal requirements for chemicals to achieve a specified separation duty, and therefore attract more concerns in the process design of countercurrent extraction separation. Over the past decade, hyperlink extraction technology has been widely used in rare earth separation industry in China with the target to decrease chemical consumption as well as pollution discharges. However, the equations of Smin and Wmin derived in the earlier version of the theory of countercurrent extraction can only be correctly applied to two-component separation and become invalid for hyperlink processes. It is significant to develop new aspects of the theory for design of the hyperlink processes. The separation of (A1A2···At-1)/(A2A3···At) is the basic configuration in the hyperlink processes differently from in conventional processes, where A1, A2, ···, At represent different kinds of rare earth ions with the same number of valence. The separations of two and three components have been discussed and the equations of Smin and Wmin are derived in our previous works. Nevertheless, it is still significant, especially for rare earth separations, to investigate the separations with more components. The present article will therefore focus on developing new expressions for Smin and Wmin applied to the (A1A2···At﹣1)/(A2A3···At) separation. Also a five-component separation case is simulated according to the derived equations. This work is an essential part of the new theory to design the hyperlink extraction processes.
One-pot synthesis of spiroglycol
Jun Ming Xu, Fu Sheng Liu, Shi Tao Yu
Bulletin of the Chemical Society of Ethiopia , 2008,
Abstract: The synthesis of spiroglycol by one-pot reaction was studied using pentaerythritol, isobutyraldehyde and formaldehyde as starting materials. Under the optimum reacting conditions, the yield and purity of product were 93.6 % and 99.0 %, respectively. Compared to the synthesis methods reported in literatures, not only was the yield of product improved, but also two operating units were omitted. The product was characterized by 1H NMR and IR. KEY WORDS: One-pot synthesis, Spiroglycol, Pentaerythritol Bull. Chem. Soc. Ethiop. 2008, 22(1), 149-152.
One-pot synthesis of spiroglycol
Jun Ming Xu,Fu Sheng Liu,Shi Tao Yu
Bulletin of the Chemical Society of Ethiopia , 2008,
Abstract: The synthesis of spiroglycol by one-pot reaction was studied using pentaerythritol, isobutyraldehyde and formaldehyde as starting materials. Under the optimum reacting conditions, the yield and purity of product were 93.6 % and 99.0 %, respectively. Compared to the synthesis methods reported in literatures, not only was the yield of product improved, but also two operating units were omitted. The product was characterized by 1H NMR and IR.
Gearbox Scheme in High Temperature Reactor Helium Gas Turbine System  [PDF]
Sheng Liu, Xuanyu Sheng
World Journal of Nuclear Science and Technology (WJNST) , 2012, DOI: 10.4236/wjnst.2012.23014
Abstract: Helium Turbine is used in High Temperature Reactor Helium Gas Turbine (HTR-GT) system, by which the direct helium circulation between the reactor and turbine generator system will come true. Between helium turbine and generator, there is gearbox device which reduces the turbine rotation speed to normal speed required by the generator. Three optional gearbox schemes are discussed. The first is single reduction cylindrical gearbox, which consists of one high speed gear and one low speed gear. Its advantage is simple structure, easy to manufacture, and high reliability, while its disadvantage is large volume and misalignment of input and output axle. The second is planetary gear mechanism with static planet carrier. The third is planetary gear mechanism with static internal gear. The latter two gearbox devices have similar structure. Their advantage is small volume and high reduction gear ratio, while disadvantage are complicated structure, many gears, low reliability and low mechanical efficiency.
[(E)-(1-Phenylethylidene)amino]urea methanol monosolvate
Guang-Bin Liu,Peng-Sheng Chen,Chang-Xiang Liu,Ling Fu
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811000225
Abstract: In the title compound, C9H11N3O·CH4O, the semicarbazone moiety is nearly planar [maximum deviation = 0.017 (2) ] and is twisted by a dihedral angle of 29.40 (13)° with respect to the phenyl ring. The semicarbazone moiety and phenyl ring are located on opposite sides of the C=N bond, showing the E configuration. An intermolecular O—H...O and N—H...O hydrogen-bonding network occurs in the crystal structure.
Landau hydrodynamical model at RHIC and LHC
Sheng-Xu Liu,Hui-Jie Wang,Fu-Ming Liu
Physics , 2012,
Abstract: The rapidity distribution and transverse spectra of most copious particles such as pions, Kaons and antiprotons from central Au+Au collisions at $\sqrt{s_{NN}}=200$ GeV and central Pb+Pb collisions at $\sqrt{s_{NN}}=2.76$ TeV have been investigated in the framework of Landau hydrodynamical model. With a more realistic choice of freeze-out condition and the employment of lattice equation of state, we find transverse expansion of the collision systems is important to explain the observed data. With the increase of collision energy from RHIC to LHC, transverse flow becomes more and more important for hadron production at midrapidity, especially for more massive particle.
Anisotropic emission of thermal dielectrons from Au+Au collisions at $\sqrt{s_{NN}}=200$~GeV with EPOS3
Sheng-Xu Liu,Fu-Ming Liu,Klaus Werner,Meng Yue
Physics , 2015,
Abstract: Dileptons, as an electromagnetic probe, are crucial to study the properties of Quark-Gluon Plasma (QGP) created in heavy ion collisions. We calculated the invariant mass spectra and the anisotropic emission of thermal dielectrons from Au+Au collisions at the Relativistic Heavy Ion Collider (RHIC) energy $\sqrt{s_{NN}}=200$~GeV based on EPOS3. This approach provides a realistic (3+1)-dimensional event-by-event viscous hydrodynamic description of the expanding hot and dense matter with a very particular initial condition, and a large set of hadron data and direct photons (besides $v_{2}$ and $v_{3}$ !) can be successfully reproduced. Thermal dilepton emission from both QGP phase and the hadronic gas are considered, with the emission rates based on Lattice QCD and a vector meson model, respectively. We find that the computed invariant mass spectra (thermal contribution + STAR cocktail) can reproduce the measured ones from STAR at different centralities. Different from other model predictions, the obtained elliptic flow of thermal dileptons is larger than the STAR measurement referring to all dileptons. A clear centrality dependence of thermal dilepton occurs not only to elliptic flow $v_{2}$ but also to high orders for centrality in 0-60\%. At a given centrality, $v_{n}$ of thermal dileptons decreases neatly with $n$ for $2 \leq n \leq 5$.
MicroRNA-34c Enhances Murine Male Germ Cell Apoptosis through Targeting ATF1
Xiaoxuan Liang, Doudou Zhou, Chao Wei, Haoshu Luo, Jiali Liu, Rui Fu, Sheng Cui
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0033861
Abstract: Background MicroRNAs (miRNAs) play vital regulatory roles in many cellular processes. The expression of miRNA (miR)-34c is highly enriched in adult mouse testis, but its roles and underlying mechanisms of action are not well understood. Methodology/Principal Findings In the present study, we show that miR-34c is detected in mouse pachytene spermatocytes and continues to be highly expressed in spermatids. To explore the specific functions of miR-34c, we have established an in vivo model by transfecting miR-34c inhibitors into primary spermatocytes to study the loss-of-function of miR-34c. The results show that silencing of miR-34c significantly increases the Bcl-2/Bax ratio and prevents germ cell from apoptosis induced by deprivation of testosterone. Moreover, ectopic expression of the miR-34c in GC-2 cell trigger the cell apoptosis with a decreased Bcl-2/Bax ratio and miR-34c inhibition lead to a low spontaneous apoptotic ratio and an increased Bcl-2/Bax ratio. Furthermore, ectopic expression of miR-34c reduces ATF1 protein expression without affecting ATF1 mRNA level via directly binding to ATF1's 3′UTR, indicating that ATF1 is one of miR-34c's target genes. Meanwhile, the knockdown of ATF1 significantly decreases the Bcl-2/Bax ratio and triggers GC-2 cell apoptosis. Inhibition of miR-34c does not decrease the GC-2 cell apoptosis ratio in ATF1 knockdown cells. Conclusions/Significance Our study shows for the first time that miR-34c functions, at least partially, by targeting the ATF1 gene in germ cell apoptosis, providing a novel mechanism with involvement of miRNA in the regulation of germ cell apoptosis.
Exploring the binding of BACE-1 inhibitors using comparative binding energy analysis (COMBINE)
Shu Liu, Rao Fu, Xiao Cheng, Sheng-Ping Chen, Li-Hua Zhou
BMC Structural Biology , 2012, DOI: 10.1186/1472-6807-12-21
Abstract: By considering the contributions of the protein residues to the electrostatic and van der Waals intermolecular interaction energies, two predictive and robust COMBINE models were developed: (i) the 3-PC distance-dependent dielectric constant model (built from a single X-ray crystal structure) with a q2 value of 0.74 and an SDEC value of 0.521; and (ii) the 5-PC sigmoidal electrostatic model (built from the actual complexes present in the Brookhaven Protein Data Bank) with a q2 value of 0.79 and an SDEC value of 0.41.These QSAR models and the information describing the inhibition provide useful insights into the design of novel inhibitors via the optimization of the interactions between ligands and those key residues of BACE-1.It is generally accepted that Alzheimer’s disease (AD) is caused by extracellular amyloid plaque deposition and the intracellular formation of neurofibrillary tangles in the brain [1-4]. β-amyloid peptides (Aβ, forming the amyloid plaques) are formed by the action of the β-secretase (BACE-1) and γ-secretase enzymes on the amyloid precursor protein (APP) [5-8]. BACE-1 is currently widely accepted as a leading target for the therapeutic treatment of AD [9-12]. The inhibition of BACE-1 can prevent the cleavage of APP to Aβ and the formation of amyloid plaques [13].The search for potent BACE-1 inhibitors is being pursued actively in many academic institutes and pharmaceutical companies. Most of these endeavors include computational studies such as pharmacophore modeling [14,15], classical quantitative structure-activity relationships (QSARs) [14-17], docking and virtual screening [18-22] and molecular dynamics (MD) simulations [23-26]. Currently, several hundred BACE-1 inhibitors have been reported, but most of these inhibitors are peptidomimetics [16]. To find novel BACE-1 inhibitors, a few companies are actively screening against BACE-1. A research group from Merck has performed in vitro high-throughput screening (HTS) and found a single molecule
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