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Search Results: 1 - 10 of 518 matches for " Friederike Fleischer "
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La diáspora china: un acercamiento a la migración china en Colombia
Friederike Fleischer
Revista de Estudios Sociales , 2012,
Abstract: The Chinese diaspora is the largest and most extensive among the world's migrant populations. Recent estimates put the number of Chinese emigrants at 40 million people. Far from being a homogenous group, members of the Chinese diaspora have diverse economic, cultural, social, educational, and personal backgrounds as well as very different life stories and emigration experiences. Despite the growing interest in the Pacific Rim and the constant immigration of Chinese to the Americas through the 20[th] century, there is very little information about their migration to Colombia. This article explores the topic from a historical point of view in order to fill this void. The little that is known about Chinese migrants to Colombia is presented in the context of a discussion on the diaspora in order to highlight the transnationality and multiplicity of identities among this migrant group. The article also examines the similarities and differences between Chinese migration to Colombia and other countries in Latin America and on other continents, relating these particularities to local contexts.
Immunological Responses and Actin Dynamics in Macrophages Are Controlled by N-Cofilin but Are Independent from ADF
Friederike J?nsson, Christine B. Gurniak, Bernhard Fleischer, Gregor Kirfel, Walter Witke
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036034
Abstract: Dynamic changes in the actin cytoskeleton are essential for immune cell function and a number of immune deficiencies have been linked to mutations, which disturb the actin cytoskeleton. In macrophages and dendritic cells, actin remodelling is critical for motility, phagocytosis and antigen presentation, however the actin binding proteins, which control antigen presentation have been poorly characterized. Here we dissect the specific roles of the family of ADF/cofilin F-actin depolymerizing factors in macrophages and in local immune responses. Macrophage migration, cell polarization and antigen presentation to T-cells require n-cofilin mediated F-actin remodelling. Using a conditional mouse model, we show that n-cofilin also controls MHC class II-dependent antigen presentation. Other cellular processes such as phagocytosis and antigen processing were found to be independent of n-cofilin. Our data identify n-cofilin as a novel regulator of antigen presentation, while ADF on the other hand is dispensable for macrophage motility and antigen presentation.
Synthesis and Plasma Stability of Disulfide-Bridged Cyclic Endomorphin-1 Derivatives  [PDF]
Friederike M. Mansfeld, Istvan Toth
International Journal of Organic Chemistry (IJOC) , 2012, DOI: 10.4236/ijoc.2012.21001
Abstract: Endomorphin-1 is an endogenous opioid peptide that mediates pain relief through interaction with the μ-opioid receptor in the central nervous system. To enhance the metabolic stability of this tetrapeptide, cyclisation through the formation of a disulfide bridge between the side chains of cysteine residues added to the sequence was explored. A further increase in stability was achieved through N-terminal modification with lipoamino acid and lactose succinamic acid, and the inclusion of D-amino acids. The latter also provided an alternative spatial arrangement of the aromatic side chains. The lipidated cyclic derivatives were insoluble in aqueous buffer, however, the cyclic peptides and glycopeptides showed greatly improved stability towards enzymatic degradation in human plasma.
The Bernhard Nocht Institute: 100 years of tropical medicine in Hamburg
Fleischer, Bernhard;
Memórias do Instituto Oswaldo Cruz , 2000, DOI: 10.1590/S0074-02762000000700003
Abstract: the bernhard nocht institute (bni) is a four months younger and much smaller sibling of the instituto oswaldo cruz. it was founded on 1 october 1900 as an institut für schiffs- und tropenkrankheiten (institute for maritime and tropical diseases) and was later named after its founder and first director bernhard nocht. today it is the germany's largest institution for research in tropical medicine. it is a government institution affiliated to the federal ministry of health of germany and the department of health of the state of hamburg. as the center for research in tropical medicine in germany the bni is dedicated to research, training and patient care in the area of human infectious diseases, which are of particular relevance in the tropics. it is the primary mission of the bni to develop means to the control of these diseases. secondary missions are to provide expertise for regional and national authorities and to directly and indirectly improve the health care for national and regional citizens in regard to diseases of the tropics.
Ent?o, minha filha, vamos se afomentar?Puxa??o, parteiras e reprodu??o em Melga?o, Pará
Ciência & Saúde Coletiva , 2008, DOI: 10.1590/S1413-81232008000300011
Abstract: this article presents ethnographic data, collected between 2004 and 2005, about the obstetric service offered by a group of 21 midwives in the city of melga?o, state of pará, brazil. the literature has largely described the work of midwives in brazil and in many other countries around the world. however, there is a kind of practice, which was analyzed very scarcely up to now. the objective of this article is to discuss precisely the practice called puxa??o, an abdominal massage performed mainly on pregnant women to alleviate indispositions, inform the position and sex of the fetus, help define the date and place of delivery, socialize women for maternity and put pregnancy into the context of the local patterns of reproduction, family, well being and health. it can be observed that these midwives offer a very suitable and appropriate pre-natal service, well adapted to the specific needs of the women of the town. even though homebirth has been slowly giving way to hospital birth, this personalized service and practice keeps increasing.
As elei??es municipais no Brasil: uma análise comparativa (1982-2000)
Fleischer, David;
Opini?o Pública , 2002, DOI: 10.1590/S0104-62762002000100005
Abstract: this article analyses the electoral results for the first round and second round of the 2000 local elections in brazil. it focuses on the performance of each of the main political parties and some of the major candidates, in the country regions and the main cities, it analyses the general performance of women candidates, and the author searchs to make some considerations about the impact of the electoral results on the political scenery of the 2002 general elections.
Uso e circula??o de medicamentos em um bairro popular urbano na Ceilandia, DF
Fleischer, Soraya;
Saúde e Sociedade , 2012, DOI: 10.1590/S0104-12902012000200014
Abstract: in the suburbs of brasilia, family health is taken care of in particular by elderly women. they know the official and non-official shortcuts inside the health system, medicines that each of the family members should take and the places where medicines can be bought cheaper or received for free. they also make experiments with pills and capsules - each ones are strong or dangerous, which ones have to be substituted or combined with different drugs, etc. this paper aims to discuss how informal networks sharing pharmaceutical knowledge and local forms of communication between family members, neighbors and health professionals determine a wider, more complex understanding of health. it is based on an ethnographic research with older residents of guariroba district in ceilandia, df, which are in familiar terms with hypertension and diabetes mellitus. some of the data that support the discussion are the life stories of these migrants towards the federal district (brasilia region, in brasil); the consumption of drugs as a generator of bodily and social experiences of falling ill; self-medication as a practice even after having been seen at the local health agents. this paper wants to emphasize that technical opinion and products offered by official agents of health care did not prevent interviewed women of resorting regularly to a much wider and creative network, neither replaced it. it wants also to show that to perfection this network is a public demonstration of involvement and commitment of these caregivers with their patients' recovery or stability.
End-of-life decisions and the law: a new law for South Africa?
T Fleischer
Continuing Medical Education , 2003,
CP Violation and B Physics at the LHC
Fleischer, Robert
High Energy Physics - Phenomenology , 2007,
Abstract: In this decade, there are huge efforts to explore B-meson decays, which provide an interesting playground for stringent tests of the Standard-Model description of the quark-flavour sector and the CP violation residing there. Thanks to the $e^+e^-$ B factories at KEK and SLAC, CP violation is now a well-established phenomenon in the B-meson system, and recently, also $B^0_s$--$\bar B^0_s$ mixing could be measured at the Tevatron. The decays of $B^0_s$ mesons are the key target of the B-physics programme at the LHC, and will be the focus of this presentation, discussing the theoretical aspects of various benchmark channels and the question of how much space for new-physics effects in their observables is left by the recent experimental results.
Theoretical Review of $\gamma/\phi_3$ Measurements with $B_s$ Decays to Charm
Fleischer, Robert
High Energy Physics - Phenomenology , 2007,
Abstract: We give an overview of various determinations of $\gamma/\phi_3$ with the help of $B_s$ decays into charmed final states, distinguishing between transitions with tree and penguin contributions and pure tree decays. In the corresponding strategies, the $U$-spin flavour symmetry of strong interactions provides a very useful tool, and offers interesting "by-producs" for the $B$-physics programme at the LHC, including the control of the penguin uncertainties in the determinations of the $B^0_d$-$\bar B^0_d$ and $B^0_s$--$\bar B^0_s$ mixing phases $\phi_d$ and $\phi_s$ from $B_d\to J/\psi K_S$ and $B_s\to J/\psi\phi$, respectively, and an alternative extraction of the latter phase through $B_s\to D_s^+D_s^-$. Finally, we point out that the cleanest determinations of the mixing phases $\phi_s$ and $\phi_d$ are offered by the pure tree decays $B_s\to D_\pm K_{S(L)}$ and $B_d\to D_\pm\pi^0, D_\pm\rho^0, ...$, respectively, which are very interesting for the searches of new physics.
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