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Search Results: 1 - 10 of 8123 matches for " Franco-Paredes "
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The Stigmatization of Leprosy in India and Its Impact on Future Approaches to Elimination and Control
Jesse T. Jacob ,Carlos Franco-Paredes
PLOS Neglected Tropical Diseases , 2008, DOI: 10.1371/journal.pntd.0000113
A Woman with Chronic Subcutaneous Swelling of the Right Foot Associated with Sinus Tracts Discharging Yellow Grains
Ildefonso Tellez,Carlos Franco-Paredes
PLOS Neglected Tropical Diseases , 2010, DOI: 10.1371/journal.pntd.0000772
Freedom, Justice, and Neglected Tropical Diseases
Carlos Franco-Paredes ,Jose I. Santos-Preciado
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0001235
The Unfinished Public Health Agenda of Chagas Disease in the Era of Globalization
Carlos Franco-Paredes ,Maria Elena Bottazzi,Peter J. Hotez
PLOS Neglected Tropical Diseases , 2009, DOI: 10.1371/journal.pntd.0000470
A Latin American Man with Palpitations, Dizziness, Episodes of Nonsustained Ventricular Tachycardia, and an Apical Aneurysm
Anis Rassi Jr ,Anis Rassi,Carlos Franco-Paredes
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0000852
Leprosy: a modern assessment of an ancient neglected disease
Margoles, Lindsay;Río, Carlos del;Franco-Paredes, Carlos;
Boletín médico del Hospital Infantil de México , 2011,
Abstract: leprosy or hansen's disease is a chronic mycobacterial infectious disease caused by mycobacterium leprae and affects mainly peripheral nerves and skin as well as upper respiratory mucosae. this infection is a conjoined bacteriological and immunological disease. target cells of infection are macrophages, histiocytes in the skin, and the nonmyelinating and myelinating schwann cells in the peripheral nerves leading to axonal dysfunction and demyelination leading to functional impairment and deformity. leprosy reactions represent the most important determinant of nerve impairment if untreated and unrecognized. control of leprosy transmission remains a challenge despite substantial improvements through the use of multidrug therapy in many settings. most importantly, although many patients have been microbiologically cured through the efforts of the world health organization, many are left with significant disability that has recently been estimated to be ~20% of those treated (~15 million individuals) in the last decades. further efforts are needed to elucidate the epidemiology and risk factors for disability among those with multibacillary forms.
Are leprosy reactions autoinflammatory diseases?
Quandelacy, Talia;Holtz, Meredith;Franco-Paredes, Carlos;
Boletín médico del Hospital Infantil de México , 2011,
Abstract: there are two types of leprosy reactions: reversal reactions or type 1 and erythema nodosum leprosum or type 2. deformity and disability associated with leprosy are frequently the result of uncontrolled or untreated reactions. although there is current availability of glucocorticoids as the mainstay of therapy, much needs to be learned about the etiology, risk factors, and pathogenesis of leprosy reactions. there is some evidence that leprosy reactions may represent, particularly, erythema nodosum leprosum autoinflammatory disease due to the aberrant activation of the innate immune system. the role for herpesviruses influencing autophagy in macrophages needs to be evaluated in the pathogenesis of leprosy reactions.
Bioterrorismo: un nuevo problema de salud pública
Río-Chiriboga Carlos del,Franco-Paredes Carlos
Salud Pública de México , 2001,
The first influenza pandemic in the new millennium: lessons learned hitherto for current control efforts and overall pandemic preparedness
Franco-Paredes Carlos,Carrasco Peter,Preciado Jose
Journal of Immune Based Therapies and Vaccines , 2009, DOI: 10.1186/1476-8518-7-2
Abstract: Influenza viruses pose a permanent threat to human populations due to their ability to constantly adapt to impact immunologically susceptible individuals in the forms of epidemic and pandemics through antigenic drifts and antigenic shifts, respectively. Pandemic influenza preparedness is a critical step in responding to future influenza outbreaks. In this regard, responding to the current pandemic and preparing for future ones requires critical planning for the early phases where there is no availability of pandemic vaccine with rapid deployment of medical supplies for personal protection, antivirals, antibiotics and social distancing measures. In addition, it has become clear that responding to the current pandemic or preparing for future ones, nation states need to develop or strengthen their laboratory capability for influenza diagnosis as well as begin preparing their vaccine/antiviral deployment plans. Vaccine deployment plans are the critical missing link in pandemic preparedness and response. Rapid containment efforts are not effective and instead mitigation efforts should lead pandemic control efforts. We suggest that development of vaccine/antiviral deployment plans is a key preparedness step that allows nations identify logistic gaps in their response capacity.
Two Patients with Leprosy and the Sudden Appearance of Inflammation in the Skin and New Sensory Loss
Carlos Franco-Paredes ,Jesse T. Jacob,Barbara Stryjewska,Leo Yoder
PLOS Neglected Tropical Diseases , 2009, DOI: 10.1371/journal.pntd.0000425
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