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Search Results: 1 - 10 of 262219 matches for " Francisco Javier Paulín-Martínez "
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Implementation of the Hough Transform for Iris Detection and Segmentation  [PDF]
Francisco Javier Paulín-Martínez, Alberto Lara-Guevara, Rosa María Romero-González, Hugo Jiménez-Hernández
Advances in Molecular Imaging (AMI) , 2019, DOI: 10.4236/ami.2019.91002
Abstract: The iris is used as a reference for the study of unique biometric marks in people. The analysis of how to extract the iris characteristic information represents a fundamental challenge in image analysis, due to the implications it presents: detection of relevant information, data coding schemes, etc. For this reason, in the search for extraction of useful and characteristic information, approximations have been proposed for its analysis. In this article, it is presented a scheme to extract the relevant information based on the Hough transform. This transform helps to find primitive geometries in the irises, which are used to characterize each one of these. The results of the implementation of the algorithm of the Hough transform applied to the location and segmentation of the iris by means of its circumference are presented in the paper. Two public databases of iris images were used: UBIRIS V2 and CASIA-IrisV4, which were acquired under the same conditions and controlled environments. In the pre-processing stage the edges are found from the noise elimination in the image through the Canny detector. Subsequently, to the images of the detected edges, the Hough transform is applied to the disposition of the geometries detected.
Laparoscopic versus laparotomy approach to endometrial cancer: A prospective study  [PDF]
López-De la Manzanara Carlos, Martín-Francisco Cástor, Luengo-Tabernero ángel, Garrido-Esteban Rosa Ana, León-Martín Alberto, Haya-Palazuelos Javier
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.34077

Objective: The aim of this study was to compare laparoscopic (LPS) and laparotomy (LPT) approaches for endometrial cancer, and to assess intraoperative and postoperative results, disease-free survival and overall survival. Methods: We designed a prospective observational study, every patient diagnosed of endometrial cancer and subsidiary to surgical staging was included. Total hysterectomy, bilateral adnexectomy, pelvic lymphadenectomy were performed in every case. Paraaortic lymphadenectomy was performed depending on tumor histology. Results: 70 patients with endometrial cancer were enrolled, 49 (70%) were treated laparoscopically and 21 (30%) laparotomically. There was not statistical significant difference in the mean operative time, it was 183.06 ± 21.03 min (range 120 - 230) in the LPS group and 195.24 ± 28.39 min (range 130 - 240) in the LPT group, mean difference 12.16 (95% CI 0.2 - 24). There was no difference in the number of lymph nodes resected. Mean blood loss was lower in the LPS group. There were less postoperative complications, 3 (6.12%) in the LPS group and 7 (33.3%) in the LPT group (p < 0.01). Mean hospital stay was significantly shorter in the LPS group 4.29 ± 1.62 days vs 8.81 ± 3.37 days in the LPT group (p < 0.01), mean difference 4.52 (95% CI 3.3 - 5.7). Overall survival was similar in both groups. Conclusion: Laparoscopic approach for endometrial cancer offers similar results in terms of survival and oncological radicality as the laparotomic approach and a lower rate of complications, a quicker convalescence time and a shorter hospital stay.

El Extracto Acuoso de Orégano (Lippia graveolens HBK) del Norte de México Tiene Actividad Antioxidante sin Mostrar un Efecto Tóxico in vitro e in vivo
Soto-Domínguez,Adolfo; García-Garza,Rubén; Ramírez-Casas,Yolanda; Morán-Martínez,Javier; Serrano-Gallardo,Luis Benjamín;
International Journal of Morphology , 2012, DOI: 10.4067/S0717-95022012000300029
Abstract: since ancient times, traditional medicine has widely used species of the genus lippia as analgesics, anti-inflammatory, antipyretic, antifungal, etc. numerous studies describe several compounds present in aqueous extracts, methanol, or essential oils of these plants, being flavonoids the most abundant compounds. however, the composition and quantity of secondary metabolites depend on the geographical area, climatic factors, altitude, time of harvest and growth status of these plants. the objective of this study was to evaluate the antioxidant activity of aqueous extract of oregano (lippia graveolens hbk) from the north of mexico and its toxic effect in vitro and in vivo. the antioxidant activity of the aqueous extract was measured by dpph method in six dilutions of the extract (5-160 mg / ml), trolox was used as a reference. for the in vitro toxic effect, cytotoxicity assay with larvae of artemia salina was used. for the in vivo effect, 24 males mice were used and divided into 6 groups (n = 4): 4 experimental groups with 10, 100, 1000 and 5000 mg extract / kg body weight administered orally respectively, also we used a group positive control (5 mg of colchicine / kg body weight administered via ip) and a negative control group (distilled water only). after treatment all mice were sacrificed, and samples from liver and kidney were collected and analyzed by histological and histochemical studies. also a quantitative analysis was done. the antioxidant activity of aqueous extract of oregano was presented at 160 mg/ml. the lc50 was greater than 1.000 mg/ml, so the extract is considered nontoxic. in the morphological analysis in vivo with different doses of aqueous extract of oregano, no toxic effect was observed. the results validate the use of oregano in traditional medicine.
Composición isotópica de carbono en follaje de Pinus pinceana Gordon sometido a estrés hídrico y térmico
Marti?ón-Martínez, R. Julián;Vargas-Hernández, J. Jesús;Gómez-Guerrero, Armando;López-Upton, Javier;
Agrociencia , 2011,
Abstract: pinus pinceana gordon grows in semiarid conditions in the northeast and central east of méxico. probably it is facing a high risk of disappearing due to increased temperature and drought associated with the climate change forecast. in order to understand the physiological mechanisms in the adaptation of this species to environmental stress conditions and define management options for the conservation and restoration of its natural populations, we studied the variation in carbon isotope composition (δ13c) and in the relative growth rate (rgr) in plants of six populations of p. pinceana subjected to water stress and high temperature under greenhouse conditions. the study populations represented a north-south transect of the natural distribution of the species in mexico. in a factorial experiment, two temperature environments were tested [without changing the temperature (t0) and with an increase of 2 °c (t1) in average temperature] and two levels of humidity [gravimetric content of 50 % (s0) and 12-20 % (sj) soil moisture]. temperature did not influence the value of δ13c, but water stress caused a significant reduction in 13c discrimination (higher δ13c). the effect was greater without stress temperature (to). a significant variation among populations was found in δ13c values. in the two moisture conditions, the northern populations exhibited greater δ13c and higher rgr in height, compared to the southern. the (δ13c values of populations were positively correlated with the rgr in height, but not with biomass accumulation. the analysis of results shows that water use efficiency, estimated indirectly through the value of δ13c, has an important role in the adaptation capacity of p. pinceana populations to the drought conditions it faces at its natural habitat; it is also possible to identify populations of the species with the possibility to adjust to conditions of greater environmental stress associated with climate change.
Alteraciones Morfológicas en el Tracto Respiratorio de Ratas Wistar Inducidas por Vapores de la Raíz de Hierba del Zorrillo (Petiveria alliacea) del Suroeste de México Morphologic Alterations in the Respiratory Tract of Wistar Rats Induced by Steams of the Root of Hierba del Zorrillo (Petiveria alliacea) from Southwest of Mexico
Víctor M Fletes-Arjona,Adolfo Soto-Domínguez,Rubén García-Garza,Javier Morán-Martínez
International Journal of Morphology , 2013,
Abstract: Petiveria alliacea, es conocida con diferentes nombres según el lugar donde se le encuentre. Estudios con hojas, tallo, raíz o extractos describen múltiples usos medicinales. Sin embargo, son pocos los que describen efectos tóxicos. En este estudio se evaluó el efecto morfológico de los vapores de la raíz de P. alliacea sobre el tracto respiratorio de ratas Wistar. Se emplearon 15 ratas divididas en 5 grupos (n=3): control absoluto, 0, 5, 15 y 30 minutos post-exposición (grupos I-V, respectivamente). Las ratas se sacrificaron y se colectaron muestras representativas del tracto respiratorio que posteriormente se procesaron por la técnica histológica convencional, hasta su inclusión en bloques de parafina. Los cortes histológicos se ti eron con H-E, tricrómico de Masson y azul de toluidina. En tráquea, bronquiolos y pulmón de las ratas de los grupos I y II se observó una histología normal. En la tráquea de los grupos III, IV y V se identificaron áreas variables de hiperplasia en el epitelio, zonas desprovistas de cilios, signos de aumento en la secreción de las células caliciformes y áreas desprovistas de epitelio que se incrementaron con el tiempo. En la lámina propia se observó congestión vascular e infiltrado mononuclear que incrementó con el tiempo. En los bronquiolos de los grupos III y IV se observó activación de las células de Clara, áreas desprovistas de epitelio, y células mononucleares en la luz bronquiolar. En el grupo V se observaron características histológicas normales. En pulmón de los grupos III y IV se identificó engrosamiento de tabiques alveolares, incremento de las fibras de colágena, congestión y extravasación capilar, además de exudado intralveolar. En el grupo V se observó aparente reversión de algunas alteraciones morfológicas de los grupos previos, aunque otras alteraciones persisten. No se observaron diferencias en el número de las células cebadas. Petiveria alliacea, is known with different names depending of the place where it is found. Studies with leaves, stem, root or extracts, describe multiple medicinal uses. However, there are few reports that describe toxic effects. This study assessed the morphologic effect induced by steams of the root of P. alliacea on the respiratory tract of Wistar rats. We used 15 rats divided in 5 groups (n= 3): absolute control, 0, 5, 15 and 30 minutes post-exposure (I-V groups, respectively). The rats were sacrificed; representative samples of the respiratory tract were collected, and were processed by conventional histological technique until their inclusion in paraffin blocks. Histological sect
El Extracto Acuoso de Orégano (Lippia graveolens HBK) del Norte de México Tiene Actividad Antioxidante sin Mostrar un Efecto Tóxico in vitro e in vivo The Aqueous Extract from Oregano (Lippia graveolens HBK) from the North of Mexico Has Antioxidant Activity without Showing a Toxic Effect in vitro and in vivo
Adolfo Soto-Domínguez,Rubén García-Garza,Yolanda Ramírez-Casas,Javier Morán-Martínez
International Journal of Morphology , 2012,
Abstract: Desde tiempos antiguos la medicina tradicional ha usado extensamente las especies del género Lippia como analgésicos, antiinflamatorios, antipiréticos, antifúngicos, etc. Numerosos estudios describen diversos compuestos presentes en extractos acuosos, metanólicos, o aceites esenciales de estas plantas, siendo los flavonoides los compuestos más abundantes. Sin embargo, la composición y cantidad de los metabolitos secundarios dependen de la zona geográfica, factores climáticos, altitud, época de cosecha y estado de crecimiento de estas plantas. El objetivo de este estudio fue evaluar la actividad antioxidante del extracto acuoso de orégano (Lippia graveolens HBK) del Norte de México y su efecto tóxico in vitro e in vivo. La capacidad antioxidante del extracto acuoso se midió por el método de DPPH en seis diluciones del extracto (5-160 mg/mL) y se utilizó Trolox como referencia; para el efecto tóxico in vitro se usó el ensayo de citotoxicidad con larvas de Artemia salina. Para el efecto in vivo se emplearon 24 ratones árabes machos divididos en 6 grupos de animales (n=4): 4 grupos experimentales con 10, 100, 1000 y 5000 mg del extracto/ kg de peso administrados vía oral respectivamente, además de un grupo control positivo (5 mg de colchicina/kg de peso vía i.p) y un grupo control negativo (solo agua destilada). Después del tratamiento los ratones se sacrificaron y se colectaron muestras de hígado y ri ón que se sometieron a estudios histológicos e histoquímicos, además se realizó un análisis cuantitativo. La actividad antioxidante del extracto acuoso de orégano se presentó a 160 mg/mL. La CL50 fue mayor a 1,000 μg/mL por lo que el extracto se considera no tóxico. En el análisis morfológico in vivo con distintas dosis del extracto acuoso de orégano no se observó un efecto tóxico. Los resultados obtenidos validan el uso del orégano en la medicina tradicional. Since ancient times, traditional medicine has widely used species of the genus Lippia as analgesics, anti-inflammatory, antipyretic, antifungal, etc. Numerous studies describe several compounds present in aqueous extracts, methanol, or essential oils of these plants, being flavonoids the most abundant compounds. However, the composition and quantity of secondary metabolites depend on the geographical area, climatic factors, altitude, time of harvest and growth status of these plants. The objective of this study was to evaluate the antioxidant activity of aqueous extract of oregano (Lippia graveolens HBK) from the North of Mexico and its toxic effect in vitro and in vivo. The antioxidant activity of the a
Respuesta de Pinus pinceana Gordon a estrés por sequía y altas temperaturas
Marti?ón-Martínez, Rodrigo J.;Vargas-Hernández, Jesús;López-Upton, Javier;Gómez-Guerrero, Armando;Vaquera-Huerta, Humberto;
Revista fitotecnia mexicana , 2010,
Abstract: to identify the potential for adaptability of pinus pinceana gordon to environmental stress associated with climate change, the effect of drought and high temperature stress on growth and biomass allocation in seedlings from 12 provenances of the species was evaluated under greenhouse conditions. the experimental design included two different temperature environments with an average difference of 2 °c, and two levels of water availability (s0 = soil water potential above -0.5 mpa; s1= soil water potential below -1.5 mpa). both factors caused a reduction (p ≤ 0.05) in shoot growth, biomass accumulation and shoot/root ratio, but the effect of water stress was two to three times higher than temperature stress. the increase in temperature caused a greater thickening of the stem, particularly when combined with water stress. a wide variation among provenances in growth potential and biomass allocation was found in response to stress factors, indicating phenotypic plasticity in their adaptation mechanisms. under stress conditions, populations from the northern region showed higher reductions in biomass accumulation and shoot/root ratio, but produced more branches than populations from the southern region. these results allow us to postulate that the species has the potential to adapt to climate change, if populations with best response to the predicted stress levels are used in conservation and ecological restoration programs.
La sociabilidad política: un juego de luces y sombras
Memoria y Sociedad , 2010,
Abstract: the concept of political sociability has been widely spread and assumed as a valid and pertinent analytical tool for studying the processes of construction of political modernity. however, it is a problematic concept, at least in terms of addressing its use. the present article has the fundamental objective of making a theoretical reflection around political sociability, as well as proposing some lines of analysis referred to the application of this category into the study of colombian cultural manifestations of the 19th century.
MicroARNs: una visión molecular
Pabón-Martínez,Y. Vladimir;
Revista de la Universidad Industrial de Santander. Salud , 2011,
Abstract: micrornas are small rnas of approximately 22 nucleotides in length that participate in the regulation of many cellular processes and it alteration is associated with the development of different pathologies in particular, cancer. using bioinformatics tools is possible determine their wide distribution in the genome and their functions in different tissues. mostly of micrornas are produced in a canonical way from a long primary transcript, in a sequential process of two reactions guided mostly by two enzymes: drosha in the nucleus and dicer in the cytoplasm. however, it has been described some pathways non-canonical for the generation of micrornas. the aim of this review is to describe the generation process of micrornas and the machinery involved in their generation for the purpose of achieving a better understanding of the different processes they are involved. salud uis 2011; 43 (3): 289-297
ARN interferente y Micro ARN: una estrategia de silenciamiento del Virus de la Inmunodeficiencia Humana RNA interference and microRNA: A strategy of silencing for the human immunodeficiency virus
Y. Vladimir Pabón-Martínez
Revista de la Universidad Industrial de Santander. Salud , 2011,
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