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Search Results: 1 - 10 of 13109 matches for " Francis Patrick Udomah "
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Association between Urinary N-Acetyl-Beta-D-Glucosaminidase and Microalbuminuria in Diabetic Black Africans
Francis Patrick Udomah,Udeme Ekpenyong Ekrikpo,Emmanuel Effa,Babatunde Salako,Ayodeji Arije,Solomon Kadiri
International Journal of Nephrology , 2012, DOI: 10.1155/2012/235234
Abstract: Diabetes mellitus is the commonest cause of ESRD worldwide and third most common cause in Nigeria. Recent reports from Nigeria indicate the prevalence of diabetic nephropathy as an aetiology of ESRD is increasing necessitating early diagnosis of diabetic nephropathy. We measured the urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG), NAG/creatinine ratio, urinary protein-creatinine ratio and calculated eGFR in 30 recently diagnosed nonhypertensive diabetics and 67 controls. The age and sex distribution, systolic blood pressure, serum and urinary creatinine were similar for both groups. There was higher urinary excretion of NAG (304 versus 184?μmol/h/L, ?? < 0 . 0 0 1 ) and NAG/creatinine ratio (21.2 versus 15.7?μmol/h/L/mmolCr, ?? < 0 . 0 0 1 ) in the diabetics than controls. There was a strong correlation between NAG/creatinine ratio and albumin/creatinine ratio ( ?? = 0 . 7 4 , ?? < 0 . 0 0 1 ). A multivariate linear regression model showed a significant linear relationship between NAG/creatinine ratio and albumin/creatinine ratio after adjusting for the effect of blood pressure, age, sex, and serum creatinine. The strong association found between albumin/creatinine ratio and NAG/creatinine ratio perhaps indicates the need for further investigation of the clinical utility of NAG/creatinine ratio as a screening tool for early nephropathy in African diabetics. 1. Introduction End-stage renal disease is on the increase worldwide. However, it is difficult to appropriately compare international data on the aetiology, incidence, and prevalence because of differences in how data for various registries are derived, different patient demographics, and quality of healthcare among others. Diabetes mellitus (DM) is still recognized in the US and Europe as the commonest cause of end-stage renal disease (ESRD). Indeed recent data from the US Renal Data System suggests that the rates of ESRD due to DM and hypertension rose by 2.2% and 2.7%, respectively, in 2009 with overall prevalent ESRD estimated at 1,738 per million population [1]. African Americans were in the majority. Reports from Europe and Asia have also shown a rise in the incidence of ESRD over the years [2–4]. In Nigeria, many hospital-based reports put diabetic nephropathy as the third most common cause of ESRD [5–7], but it appears that the proportion of ESRD caused by diabetic nephropathy is increasing [8]. In the last two decades, studies have focused on the role of glomerular injury in early diabetic nephropathy (as measured by the onset of persistent microalbuminuria), but attention is now
Flexible Optical Waveguide Bent Loss Attenuation Effects Analysis and Modeling Application to an Intrinsic Optical Fiber Temperature Sensor  [PDF]
Mustapha Remouche, Francis Georges, Patrick Meyrueis
Optics and Photonics Journal (OPJ) , 2012, DOI: 10.4236/opj.2012.21001
Abstract: The temperature dependence of the bending loss light energy in multimode optical fibers is reported and analyzed. The work described in this paper aims to extend an initial previous analysis concerning planar optical waveguides, light energy loss, to circular optical waveguides. The paper also presents à novel intrinsic fiber optic sensing device base on this study allowing to measure temperatures parameters. The simulation results are validated theoretically in the case of silica/silicone optical fiber. A comparison is done between results obtained with an optical fiber and the results obtained from the previous curved optical planar waveguide study. It is showed that the bending losses and the temperature measurement range depend on the curvature radius of an optical fiber or waveguide and the kind of the optical waveguide on which the sensing process is implemented.
Stress Sensing by an Optical Fiber Sensor: Method and Process for the Characterization of the Sensor Response Depending on Several Designs  [PDF]
Mustapha Remouche, Francis Georges, Patrick Meyrueis
Optics and Photonics Journal (OPJ) , 2013, DOI: 10.4236/opj.2013.32032
Abstract:

In this paper we propose an analyzing of the response of a stress optical fiber sensor of which we proposed several design. We show that an optical fiber sensor with these designs can covenanting allow the measuring the force/stress applied to a mechanical structure or which it is linked, by optimizing the uses of appropriate materials for constituting the sensor support. The experiment that we introduce to validate our approach based in principles includes design with a support bearing a multimode optical fiber organized in such a way that the transmitted light is attenuated when the fiber-bending angle coming from stitching in holes of the support is modified by the effects of the force/stress applied to the optical fiber sensor realized in this way. The tests realized concern the most relevant parameters that define the performances of the stress sensor that we propose. We present the problems that we to solved for the optimization of the sensor for selecting the more efficient material for the optical fiber sensor support related to a relevant choice of optical fibers.

Eulerian and Lagrangian propagators for the adhesion model (Burgers dynamics)
Francis Bernardeau,Patrick Valageas
Physics , 2009, DOI: 10.1103/PhysRevD.81.043516
Abstract: Motivated by theoretical studies of gravitational clustering in the Universe, we compute propagators (response functions) in the adhesion model. This model, which is able to reproduce the skeleton of the cosmic web and includes nonlinear effects in both Eulerian and Lagrangian frameworks, also corresponds to the Burgers equation of hydrodynamics. Focusing on the one-dimensional case with power-law initial conditions, we obtain exact results for Eulerian and Lagrangian propagators. We find that Eulerian propagators can be expressed in terms of the one-point velocity probability distribution and show a strong decay at late times and high wavenumbers, interpreted as a "sweeping effect" but not a genuine damping of small-scale structures. By contrast, Lagrangian propagators can be written in terms of the shock mass function -- which would correspond to the halo mass function in cosmology -- and saturate to a constant value at late times. Moreover, they show a power-law dependence on scale or wavenumber which depends on the initial power-spectrum index and is directly related to the low-mass tail of the shock mass function. These results strongly suggest that Lagrangian propagators are much more sensitive probes of nonlinear structures in the underlying density field and of relaxation processes than their Eulerian counterparts.
Merging and fragmentation in the Burgers dynamics
Francis Bernardeau,Patrick Valageas
Physics , 2009, DOI: 10.1103/PhysRevE.82.016311
Abstract: We explore the noiseless Burgers dynamics in the inviscid limit, the so-called ``adhesion model'' in cosmology, in a regime where (almost) all the fluid particles are embedded within point-like massive halos. Following previous works, we focus our investigations on a ``geometrical'' model, where the matter evolution within the shock manifold is defined from a geometrical construction. This hypothesis is at variance with the assumption that the usual continuity equation holds but, in the inviscid limit, both models agree in the regular regions. Taking advantage of the formulation of the dynamics of this ``geometrical model'' in terms of Legendre transforms and convex hulls, we study the evolution with time of the distribution of matter and the associated partitions of the Lagrangian and Eulerian spaces. We describe how the halo mass distribution derives from a triangulation in Lagrangian space, while the dual Voronoi-like tessellation in Eulerian space gives the boundaries of empty regions with shock nodes at their vertices. We then emphasize that this dynamics actually leads to halo fragmentations for space dimensions greater or equal to 2 (for the inviscid limit studied in this article). This is most easily seen from the properties of the Lagrangian-space triangulation and we illustrate this process in the two-dimensional (2D) case. In particular, we explain how point-like halos only merge through three-body collisions while two-body collisions always give rise to two new massive shock nodes (in 2D). This generalizes to higher dimensions and we briefly illustrate the three-dimensional (3D) case. This leads to a specific picture for the continuous formation of massive halos through successive halo fragmentations and mergings.
Exact Results for Propagators in the Geometrical Adhesion Model
Francis Bernardeau,Patrick Valageas
Physics , 2011, DOI: 10.1103/PhysRevD.85.023516
Abstract: The Geometrical Adhesion Model (GAM) we described in previous papers provides a fully solved model for the nonlinear evolution of fields that mimic the cosmological evolution of pressureless fluids. In this context we explore the expected late time properties of the cosmic propagators once halos have formed, in a regime beyond the domain of application of perturbation theories. Whereas propagators in Eulerian coordinates are closely related to the velocity field we show here that propagators defined in Lagrangian coordinates are intimately related to the halo mass function. Exact results can be obtained in the 1D case. In higher dimensions, the computations are more intricate because of to the dependence of the propagators on the detailed shape of the underlying Lagrangian-space tessellations, that is, on the geometry of the regions that eventually collapse to form halos. We illustrate these results for both the 1D and the 2D dynamics. In particular we give here the expected asymptotic behaviors obtained for power-law initial power spectra. These analytical results are compared with the results obtained with dedicated numerical simulations.
Density fields and halo mass functions in the Geometrical Adhesion toy Model
Patrick Valageas,Francis Bernardeau
Physics , 2010, DOI: 10.1103/PhysRevD.83.043508
Abstract: In dimension 2 and above, the Burgers dynamics, the so-called "adhesion model" in cosmology, can actually give rise to several dynamics in the inviscid limit. We investigate here the statistical properties of the density field when it is defined by a "geometrical model" associated with this Burgers velocity field and where the matter distribution is fully determined, at each time step, by geometrical constructions. Our investigations are based on a set of numerical experiments that make use of an improved algorithm, for which the geometrical constructions are efficient and robust. In this work we focus on Gaussian initial conditions with power-law power spectra of slope $n$ in the range $-3
Farming Families and Climate Change Issues in Niger Delta Region of Nigeria: Extent of Impact and Adaptation Strategies  [PDF]
Michael E. Ikehi, Francis M. Onu, Florence O. Ifeanyieze, Patrick S. Paradang
Agricultural Sciences (AS) , 2014, DOI: 10.4236/as.2014.512124
Abstract: The study focused on the impacts of climate change on the farmer and the farming families in Niger Delta Region of Nigeria. The study specifically evaluated the perceived resultant situations attributed to climate change to determine the extent of impacts of climate change on the farmer and the farming families and also explored adoptable strategies for coping with the situations. The study adopted descriptive survey research design. Two research questions and two hypotheses guided the study. The population for the study was 246,909 respondents made up of farmers and extension workers who are registered with the State Ministries of Agriculture. Out of the nine Niger Delta states, Bayelsa and Delta states were randomly chosen for the study. Proportionate stratified random sampling technique was used to select a sample size of 5,038 respondents. Structured questionnaire and interview were used to collect data. The instruments were validated by three experts. Cronbach Alpha method was used to determine the internal consistency of the questionnaire items which yielded a coefficient of 0.81. The Statistical Product and Service Solutions (SPSS v 20.0) was employed for data analysis. The statistical tools used for data analysis were weighted mean to answer research questions and standard deviation to validate the closeness of the respondents from the mean and from each other in their responses while t-test was used to test the null hypotheses. The findings of the study revealed that the extent of impacts of climate change on farmers and the farming families in Niger Delta region of Nigeria are moderate. Findings further revealed that climate change has led to increased poverty level and raised cost of production (input and labour cost) as indicated by the farmers. The study recommends that farmers in the region should be encouraged by providing incentives and subsidizing inputs for them by Federal and State governments as well as other non-governmental organizations, as this will go a long way in improving production especially as most farmers agree to continue cultivation even with the observed impacts.
Characterization of Multidrug Resistant Escherichia coli Isolates Recovered from Humans and Chickens, Trinidad and Tobago  [PDF]
Sandra Ashiboe-Mensah, Francis Dziva, Patrick Eberechi Akpaka, Caroline Mlambo, Abiodun A. Adesiyun
Advances in Infectious Diseases (AID) , 2016, DOI: 10.4236/aid.2016.64018
Abstract: To characterize extended-spectrum beta-lactamase (ESBL) and extra-intestinal pathogenic Escherichia coli (ExPEC) associated virulence genes in E. coli isolates from chickens and humans in Trinidad and Tobago. This cross sectional study was conducted over a three-month period. A total of 471 E. coli isolates; 160 from humans treated at a regional tertiary hospital and 311 from chicken caecal samples from pluck shops in Trinidad & Tobago were identified using both conventional and molecular microbiological methods. Phenotypic confirmation of ESBL producing E. coli isolates from humans was by Microscan system (Siemens, USA) while the double disk diffusion method was used for the chicken isolates. Polymerase chain reaction (PCR) analysis was used to determine the ESBL and ExPEC-associated virulence genes in representative human isolates and all chicken isolates. From the 311 chicken E. coli isolates, 49.2% (153/311) produced ESBL, while 56.3% (90/160) from humans were ESBL positive. All human and chicken ESBL isolates were 100% susceptible to carbapenems and aminoglycosides antimicrobials. PCR detected 21.1% blaCTX-M, 13.3% blaTEM and 7.8% bla
Orality and Medicine: The Efficacy of the Word in the Practice of Therapeutic Cures in Traditional African Medicine
Francis Mowang Ganyi,Atunka Patrick Ogar
Studies in Sociology of Science , 2012, DOI: 10.3968/2686
Abstract: The practice of medicine or herbal cures in traditional societies particularly in Africa has often been viewed with mixed feelings and sometimes with outright disdain yet it has its own history of achievements particularly in the areas of bone setting and therapeutic cures or exorcism. This notwithstanding, today in Nigeria however, one notices that modern technological innovations and education have greatly impacted on traditional medical practice and medicine men are encouraged to improve upon their practices, particularly their environments. The efficacy of traditional herbal cures in most of our societies encouraged this writer to examine some of the methods employed by the medicine men. The result of this was the interesting discovery that traditional medicine men place high priority on the power of the word as evidenced in their incantations, invocations and chants. The “word” in the healing process is seen as an appeal to a supernatural being who is summoned to the aid of the patient. That supernatural force could be the supreme God or the traditional deities believed to be in control of human existence. In the end, the writer discovered that the traditional medicine men possessed the best stock of poetical expressions and dramatic dialogue which they employ to establish a relationship or rapport between man and nature or the supernatural in the process of healing. Key words: Traditional African Medicine; Nigeria; Traditional medical practice; Herbal cures
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