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Search Results: 1 - 10 of 468551 matches for " Florencio A?ez "
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Evaluación de la Inmunidad Contra los Virus de Encefalitis Equina Venezolana y Dengue en la Población Humana de San Carlos, Municipio Insular Almirante Padilla, Estado Zulia, Venezuela. A o 1996 Evaluation of the immunity against the Venezuelan equine Encephalitis and dengue virus in the human population ofSan Carlos, insular municipality of Almirante Padilla, state of Zulia. 1996
Nereida Valero,Florencio Aez,Yraima Larreal,Julia Arias
Investigación Clínica , 2001,
Abstract: El Municipio Insular Almirante Padilla, históricamente ha sido afectado por las epidemias de Encefalitis Equina Venezolana (EEV), que se han presentado en forma cíclica, principalmente en los Municipios Páez, Mara y Almirante Padilla de la región zuliana. En la última epizoodemia (1995), los informes epidemiológicos reportaron un gran número de casos de EEV en humanos, basados en el diagnóstico clínico-epidemiológico, ocupando así este Municipio, el primer lugar en tasa de ataque por el virus de EEV. De forma similar, el Dengue se ha definido como una enfermedad endémica afectando diferentes regiones, cuyo agente etiológico tiene antecedente de circulación en la zona en estudio. Con el propósito de evaluar la inmunidad adquirida contra estos virus, se realizó un estudio serológico en la Isla de San Carlos. Se recolectaron 210 muestras de sangre obtenidas al azar, de individuos en un rango de edad comprendido entre < 1 hasta 69 a os, con y sin antecedentes de haber presentado sintomatología viral al momento del brote epidémico ocurrido en 1995. Las muestras se clasificaron según el sexo y la edad, y fueron analizadas mediante la prueba de ELISA para determinar anticuerpos IgG específicos contra los virus de EEV y Dengue. Del total de las muestras procesadas, 116 (55,2%) fueron positivas para el virus de EEV, afectando uniformemente a los grupos etarios, con ligero predominio del sexo masculino. Así mismo, se determinaron 88 casos (41,9%) positivos para el virus Dengue, cuya frecuencia se ubicó mayormente en el grupo comprendido entre 10 a 19 a os de edad. Estos resultados nos permiten sugerir que la epidemia ocurrida en el a o 1995, en el Municipio Insular Almirante Padilla, tuvo un carácter dual, al estar implicados en la etiología de los casos febriles ambos virus. The Insular Municipality of Almirante Padilla, historically, has been affected by Venezuelan Equine Encephalitis (VEE) epidemics, that have occurred cyclically in the Paez, Mara and Almirante Padilla Municipalities of the State of Zulia. During the last epidemic outbreak (1995), the studies reported a great number of cases of VEE in humans, based on epidemiologic-clinical diagnosis; occupying this municipality, the first place in the attack rate by the virus. At the same time, Dengue has been defined as an endemic illness affecting different regions, whose etiologic agent has previously circulated in the studied zone. In order to evaluate the immunity acquired against these viruses, a serological study was conducted in San Carlos Island. Two hundred and ten blood samples were obtained at ran
In mice the efficiency of immunization with Venezuelan Equine Encephalomyelitis virus TC-83 is transiently increased by dehydroepiandrosterone.
Negrette,Beatriz; Bonilla,Ernesto; Valero,Nereida; Giraldoth,Débora; Medina-Leendertz,Shirley; Aez,Florencio;
Investigación Clínica , 2001,
Abstract: to determine whether treatment with dehydroepiandrosterone (dhea) improves the efficiency of immunization against the venezuelan equine encephalomyelitis (vee) virus, mice were vaccinated with the tc-83 vee virus. dhea (10 mg/kg) was administered in a single dose, 4 hours before vaccination. igm antibody titers were determined at days 7, 14 and 21 post-immunization. treatment with dhea increased antibody titers at day 14 after immunization. mice were challenged with live vee virus at day 21, and viral titers were plaque assayed in chicken embryo fibroblasts from days 2 to 5 post-infection. after the challenge, viremia decreased on day 2 and brain virus levels were reduced at day 4 in mice treated with dhea. these results suggest that dhea treatment could enhance the efficiency of immunization against vee virus in mice.
Evaluación de la Inmunidad Contra los Virus de Encefalitis Equina Venezolana y Dengue en la Población Humana de San Carlos, Municipio Insular Almirante Padilla, Estado Zulia, Venezuela. A?o 1996
Valero,Nereida; Aez,Florencio; Larreal,Yraima; Arias,Julia; Rodríguez,Zulay; Espina,Luz Marina;
Investigación Clínica , 2001,
Abstract: the insular municipality of almirante padilla, historically, has been affected by venezuelan equine encephalitis (vee) epidemics, that have occurred cyclically in the paez, mara and almirante padilla municipalities of the state of zulia. during the last epidemic outbreak (1995), the studies reported a great number of cases of vee in humans, based on epidemiologic-clinical diagnosis; occupying this municipality, the first place in the attack rate by the virus. at the same time, dengue has been defined as an endemic illness affecting different regions, whose etiologic agent has previously circulated in the studied zone. in order to evaluate the immunity acquired against these viruses, a serological study was conducted in san carlos island. two hundred and ten blood samples were obtained at random, among individuals of an age range between < 1 and 69 years, with and without antecedents of viral illness symptomatology at the moment of the epidemic outbreak, occurred in 1995. the samples were classified according to sex and age, and analyzed through the test of elisa for specific igg antibodies against the vee and dengue viruses. from the total of the samples processed, 116 (55,2 %) were positive for vee, affecting uniformly all age - groups with a slight masculine predominance. likewise, 88 cases (41,9 %) were determined positive for dengue virus, affecting mainly the group ranging from 10 to 19 years. these results let us suggest that the epidemic outbreak occurred in 1995 at the almirante padilla insular municipality, had a double nature with both viruses being involved in the etiology of febrile cases.
Inmunidad a flavivirus en la población indígena de la Sierra de Perijá, estado Zulia, Venezuela
Valero,Nereida; Espina,Luz Marina; Estévez,Jesús; Meleán,Eddy; Larreal,Yraima; Maldonado,Mery; Arias,Julia; á?ez,Germán; Aez,Florencio; Pirela,José;
Investigación Clínica , 2004,
Abstract: little information is available about flavivirus infection in amerindian populations in western venezuela. on this account the activity and seroprevalence of these viruses were determined and the hypothesis concerning the existence of a sylvatic cycle, conditioning the infection transmission of these viruses in indigenous populations, was studied. for this, blood samples from yukpas (n=144) and barí (n=110) communities were collected, 35 (yukpas = 25 y barí =10) of which were processed for viral isolation followed by rt-pcr. the anti-flavivirus igg antibodies were determined by elisa. the results did not show active dengue cases and the seroprevalence of anti-flavivirus igg in the yukpa population was significantly higher (p < 0,0001) than in the bari population (43,1% vs. 6,4%). the present study has determined the presence of flavivirus immunity in yukpa and barí populations. these results show a higher prevalence at the former than in the bari population, which suggests circulation of flavivirus, mainly in the yukpa communities, being scarce and sporadic in bari villages. however, in the indigenous populations studied, the causes or factors that determine the off set of flavivirus infections in these zones could vary. the detected prevalence between both communities may be due to differences in the structure settlements and social habits. no evidences were found to support the presence of a sylvatic cycle in the flavivirus transmission, specially of dengue, in this population.
Incremento de Interleucina-1 beta, Interferon gamma y Factor de Necrosis Tumoral alfa en suero y cerebro de ratones infectados con el virus de Encefalitis Equina Venezolana.
Valero,Nereida; Bonilla,Ernesto; Espina,Luz Marina; Maldonado,Mery; Montero,Elsa; Aez,Florencio; Levy,Alegría; Bermudez,John; Meleán,Eddy; Nery,Anais;
Investigación Clínica , 2008,
Abstract: considerable efforts have been directed to clarify the main protective and recovery mechanisms in acute viral infections and, the possible role of the cytokines involved in the primary immune response induced by an epizootic strain of the venezuelan equine encephalitis (vee) virus. this study examined the levels of th1 cytokines interleukin-2 (il-2) and interferon-gamma (ifn-g), th2 cytokines interleukin-4 (il-4) and proinflammatory cytokines (il-1b, tnf-a) in serum and brain of mice infected with the vee virus during different post infection periods. nmri albino male mice infected with a suspension (10 dl50) of the guajira strain of the vee virus, and a control group (without infection) were used. at one, 3 and 5 days post-infection, whole blood and brains were extracted to obtain sera and brain homogenates, respectively. il-2, ifn-g, il-4, il-1b and tnf-a were determined by elisa. a significant increment in the levels of il-1b, ifn-g and tnf-a was observed (p<0.01) in serum and brain homogenates at 1, 3 and 5 day post-infection, when compared with the control group. the levels of il-2 and il- 4 did not show any significant statistical difference when compared to the controls. these results suggest that il-1b, ifn-g and tnf-a, could be involved in the early immunitary response to vee virus during the primary infection.
Evaluación retrospectiva de fiebre amarilla selvática en Venezuela, período 2003 - 2005
Finol B,Esteban; Berrueta,Eva; Levy G,Alegría; Aez M,Florencio; Espina G,Luz Marina; Maldonado E,Mery Bell; Bermudez F,John; Valero C,Nereida;
Kasmera , 2008,
Abstract: yellow fever is a viral disease, typical of some tropical regions in south america and africa, causing numerous epidemics with high mortality rates. in order to characterize retrospectively the jungle yellow fever outbreak in venezuela in the year 2003, by determining the number of cases and deaths confirmed in the affected states according to age, sex, occupation and origin and by identifying factors that triggered the outbreak, as well as the study of cases reported in 2004 and 2005, cases officially registered in the state of zulia were studied for the period in question. zulia was the state most affected during the period evaluated, with 25 cases (p <0.001), reporting the highest attack rate during 2003; merida and monagas had the highest rates in 2004, portuguesa in 2005. the most affected age group was 25-44 years, predominantly male farm workers. results showed the high lethality of yellow fever: 46.51% in 2003, 60% in 2004 and 66.67% in 2005. the implementation of measures to establish a minimum surveillance in areas with proven activity is recommended.
Evaluación de la inmunidad a los virus de sarampión y varicela en ni?os y adolescentes del Municipio Páez del Estado Zulia, Venezuela
Gotera L,Jennifer; Mavárez M,Alibeth; Hernández J,José; Aez M,Florencio; Levy G,Alegría; Duran M,Anyelo; Larreal E,Yraima; Maldonado E,Mery; Espina G,Luz; Valero C,Nereida;
Kasmera , 2009,
Abstract: exanthematic diseases are a group of pathologies caused by viral agents, which appear frequently during the first years of life and respond in greater proportion to infections caused by viruses, such as measles, varicella (chickenpox), rubella (german measles) and dengue, among others. the objective of this study is to evaluate immunity to measles and chickenpox viruses in children and adolescents residing in the páez municipality, state of zulia, venezuela. without regard to sex, 174 samples from apparently healthy adolescents and children between 8 and 17 years old were studied and analyzed using the elisa technique. a frequency of 59.7% was detected for the measles virus and 44.8% for varicella. seroprevalence for measles and varicella was distributed homogeneously in all age groups. for both diseases, greater frequency was observed in males, without significant differences. the study demonstrated low immunity to these viruses and suggests increasing vaccination programs in this municipality to eliminate circulation of these infectious agents in the population.
HIGH-RATE ANAEROBIC TREATMENT OF ALCOHOLIC WASTEWATERS
Florencio, L.;Field, J. A.;Lettinga, G.;
Brazilian Journal of Chemical Engineering , 1997, DOI: 10.1590/S0104-66321997000400016
Abstract: modern high-rate anaerobic wastewater treatment processes are rapidly becoming popular for industrial wastewater treatment. however, until recently stable process conditions could not be guaranteed for alcoholic wastewaters containing higher concentrations of methanol. although methanol can be directly converted into methane by methanogens, under specific conditions it can also be converted into acetate and butyrate by acetogens. the accumulation of volatile fatty acids can lead to reactor instability in a weakly buffered reactor. since this process was insufficiently understood, the application of high-rate anaerobic reactors was highly questionable. this research investigated the environmental factors that are of importance in the predominance of methylotrophic methanogens over acetogens in a natural mixed culture during anaerobic wastewater treatment in upflow anaerobic sludge bed reactors. technological and microbiological aspects were investigated. additionally, the route by which methanol is converted into methane is also presented
Electroprotidograma en la distrofia con edemas: (Estudio de 43 casos)
FLORENCIO A. BOLLO,RAMON MONTERO SCH
Revista chilena de pediatría , 1957,
Abstract:
Precautions for the Prevention of Plagiarism Precauciones para la prevención de plagios
Murat Enoz,José Florencio Lape?a
Revista médica de Chile , 2007,
Abstract:
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