oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 4 )

2019 ( 183 )

2018 ( 314 )

2017 ( 329 )

Custom range...

Search Results: 1 - 10 of 180413 matches for " Filomena Marino de Carvalho "
All listed articles are free for downloading (OA Articles)
Page 1 /180413
Display every page Item
How should PCNA be assessed? Total of stained cells or only the most intensely stained ones?
Kemp, Claudio;Alberti, Vania Nosé;Lima, Geraldo Rodrigues de;Carvalho, Filomena Marino de;
Sao Paulo Medical Journal , 1998, DOI: 10.1590/S1516-31801998000200005
Abstract: objective: this study aimed to analyse whether a marker of proliferative activity (pcna) could provide a prognosis of tumor evolution and to determine whether different interpretation criteria could alter the results. method: the presence of pcna in 59 patients of state ii (t2 no,1 mo) mammary carcinoma was determined. result: numerical proportions of total and intensely stained cells were established. these data were compared with anatomopathological parameters. a significant association between higher cyclin values and worse histological and nuclear grading was encountered, particularly in patients with a "negative axilla" using the pcna index. cyclin values were not significant in relation to any parameters when indices from the intensely stained cells were considered exclusively. conclusion: higher nuclear (ng3) and histological (hgiii) grading, associated with a high pcna index (>50), distinguish high-risk patients, and it is more appropriate considering all the stained cells as representative of pcna indices, thus reflecting tumor aggressiveness.
Fanconi anemia and vaginal squamous cell carcinoma
Altamiro Ribeiro Dias Jr.,Marcela Cavalcante de Andrade Silva,Filomena Marino de Carvalho,Heloisa de Andrade Carvalho
Rare Tumors , 2012, DOI: 10.4081/rt.2012.e4
Abstract: Fanconi Anemia (FA) is an autosomal recessive disease characterized by chromosome instability, cellular hypersensitivity to DNA cross-linking agents, and increased predisposition to malignancies. We describe here a 28 year-old female with FA and vaginal squamous cell carcinoma treated by radiation therapy alone. The patient developed arm phlebitis, pulmonary fungal infection, and severe rectal bleeding, followed by hypocalcaemia, hypokalemia, vaginal bacterial and fungal infection, with subsequent leg and arm phlebitis, perineal abscess, and sepsis. The patient died 12 weeks later.
Hypothyroidism following struma ovarii tumor resection: a case report
Carvalho, Jesus Paula;Carvalho, Filomena Marino;Oliveira, Flávia Fairbanks Lima de;Camargo, Rosalinda Yossie Asato de;
Revista do Hospital das Clínicas , 2002, DOI: 10.1590/S0041-87812002000300006
Abstract: struma ovarii is an infrequent ovarian tumor, and there are only few reports with detailed data of thyroid function. in several cases, malignant struma ovarii have been shown to produce hyperthyroidism, but there is no reported case of hypothyroidism following struma ovarii tumor resection. a 62-year-old white woman underwent right ovary resection that had a pathologic diagnosis of struma ovarii. after 6 days, she developed weakness, myalgia, somnolence, nausea, and arterial hypotension. laboratory tests showed a high level of thyroid-stimulating hormone (tsh) and a decreased level thyroxin. thyroxin replacement therapy was initiated, and the patient became completely asymptomatic. this is the first reported case of a previously asymptomatic woman who developed a definite clinical hypothyroidism after resection of a struma ovarii tumor.
Hypothyroidism following struma ovarii tumor resection: a case report
Carvalho Jesus Paula,Carvalho Filomena Marino,Oliveira Flávia Fairbanks Lima de,Camargo Rosalinda Yossie Asato de
Revista do Hospital das Clínicas , 2002,
Abstract: Struma ovarii is an infrequent ovarian tumor, and there are only few reports with detailed data of thyroid function. In several cases, malignant struma ovarii have been shown to produce hyperthyroidism, but there is no reported case of hypothyroidism following struma ovarii tumor resection. A 62-year-old white woman underwent right ovary resection that had a pathologic diagnosis of struma ovarii. After 6 days, she developed weakness, myalgia, somnolence, nausea, and arterial hypotension. Laboratory tests showed a high level of thyroid-stimulating hormone (TSH) and a decreased level thyroxin. Thyroxin replacement therapy was initiated, and the patient became completely asymptomatic. This is the first reported case of a previously asymptomatic woman who developed a definite clinical hypothyroidism after resection of a struma ovarii tumor.
Estudo comparativo entre uma combina o de atovaquone mais proguanil e um regime de quinino mais tetraciclina no tratamento de malária aguda por Plasmodium falciparum em adultos no Brasil
Alencar Filomena Euridice Carvalho de
Revista da Sociedade Brasileira de Medicina Tropical , 1999,
Abstract:
Conization, frozen section examination, and planned hysterectomy in the treatment of high-grade cervical intraepithelial neoplasia
Carvalho, Jesus Paula;Carvalho, Filomena Marino;Pincerato, Katia Maciel;Pereyra, Elsa A. Gay;
Revista do Hospital das Clínicas , 2001, DOI: 10.1590/S0041-87812001000600002
Abstract: purpose: we tested the role of frozen section examination of the cone specimen in the evaluation of the resection margin status and to rule out invasion in patients with high-grade cervical intraepithelial neoplasia. methods: twenty-five patients with cervical intraepithelial neoplasia underwent conization followed by frozen section examination and planned hysterectomy. the results of the definitive paraffin exam were compared with frozen section examination. results: in the evaluation of the margins by frozen section examination, 16 patients (64%) had positive cone margins and 9 (36%) had negative margins. the definitive paraffin examination of margin status was concordant in all the cases. intraoperative diagnosis of invasion was made in 5 cases, and 1 of these was microinvasive. among the remaining 20 cases, we detected 2 additional microinvasive carcinomas after paraffin study, so the diagnosis of the frozen section examination was concordant with the paraffin sections in 23/25 cases (92%). two cases of microinvasive carcinoma were diagnosed as cervical intraepithelial neoplasia by frozen section examination and had less than 2 mm stromal invasion. conclusions: in high-grade cervical intraepithelial neoplasia, frozen section examination can provide immediate and precise evaluation of the cone margin status in high-grade cervical intraepithelial neoplasia. it can identify frank invasion and permit adequate treatment in a one-stage procedure. in early microinvasive disease, frozen section examination fails to detect the area of invasion but reliably detects clear resection margins.
Müllerian adenosarcoma of the uterus with sarcomatous overgrowth following tamoxifen treatment for breast cancer
Carvalho, Filomena Marino;Carvalho, Jesus Paula;Motta, Eduardo Vieira da;Souen, Jorge;
Revista do Hospital das Clínicas , 2000, DOI: 10.1590/S0041-87812000000100004
Abstract: müllerian adenosarcoma with sarcomatous overgrowth presented by a 52-year-old female patient after adjuvant tamoxifen treatment for breast carcinoma is described. the diagnosis was made on histological basis after curettage and complementary total hysterectomy with bilateral salpingo-oophorectomy. the immunohistochemical study showed high expression of estrogen receptors in the epithelial component of the lesion and irregularly positive findings in the stroma. the proliferative activity evaluated by ki-67 immunoexpression was higher in the stroma than the epithelium. some of the stromal cells showed rhabdomyoblastic differentiation. the association of tamoxifen use and development of mesenchymal neoplasms is discussed.
Adnexal torsion following gonadotropin-releasing hormone analog therapy: a case report
Carvalho, Jesus Paula;Diegoli, Mara Solange;Carvalho, Filomena Marino;Diegoli, Carlos Alberto;
Revista do Hospital das Clínicas , 2004, DOI: 10.1590/S0041-87812004000300006
Abstract: adnexal torsion may occur in girls and adolescents. often it is associated with ovarian diseases resulting in ovarian enlargement. adnexal torsion may involve the ovary, fallopian tube or both, and the main sympton is acute pelvic pain. an 8-year-old girl complaining of acute pelvic and abdominal pain, who was previously diagnosed with precocious puberty and who received treatment with a gnrh analog, is reported. ultrasound demonstrated a normal-sized uterus and bilaterally enlarged ovaries with multiple internal cysts. at laparotomy, we found a complete torsion in the right adnexa. the histological examination revealed massive edema associated with multiple antral follicles and reduction of the follicular reserve.
Müllerian adenosarcoma of the uterus with sarcomatous overgrowth following tamoxifen treatment for breast cancer
Carvalho Filomena Marino,Carvalho Jesus Paula,Motta Eduardo Vieira da,Souen Jorge
Revista do Hospital das Clínicas , 2000,
Abstract: Müllerian adenosarcoma with sarcomatous overgrowth presented by a 52-year-old female patient after adjuvant tamoxifen treatment for breast carcinoma is described. The diagnosis was made on histological basis after curettage and complementary total hysterectomy with bilateral salpingo-oophorectomy. The immunohistochemical study showed high expression of estrogen receptors in the epithelial component of the lesion and irregularly positive findings in the stroma. The proliferative activity evaluated by Ki-67 immunoexpression was higher in the stroma than the epithelium. Some of the stromal cells showed rhabdomyoblastic differentiation. The association of tamoxifen use and development of mesenchymal neoplasms is discussed.
Conization, frozen section examination, and planned hysterectomy in the treatment of high-grade cervical intraepithelial neoplasia
Carvalho Jesus Paula,Carvalho Filomena Marino,Pincerato Katia Maciel,Pereyra Elsa A. Gay
Revista do Hospital das Clínicas , 2001,
Abstract: PURPOSE: We tested the role of frozen section examination of the cone specimen in the evaluation of the resection margin status and to rule out invasion in patients with high-grade cervical intraepithelial neoplasia. METHODS: Twenty-five patients with cervical intraepithelial neoplasia underwent conization followed by frozen section examination and planned hysterectomy. The results of the definitive paraffin exam were compared with frozen section examination. RESULTS: In the evaluation of the margins by frozen section examination, 16 patients (64%) had positive cone margins and 9 (36%) had negative margins. The definitive paraffin examination of margin status was concordant in all the cases. Intraoperative diagnosis of invasion was made in 5 cases, and 1 of these was microinvasive. Among the remaining 20 cases, we detected 2 additional microinvasive carcinomas after paraffin study, so the diagnosis of the frozen section examination was concordant with the paraffin sections in 23/25 cases (92%). Two cases of microinvasive carcinoma were diagnosed as cervical intraepithelial neoplasia by frozen section examination and had less than 2 mm stromal invasion. CONCLUSIONS: In high-grade cervical intraepithelial neoplasia, frozen section examination can provide immediate and precise evaluation of the cone margin status in high-grade cervical intraepithelial neoplasia. It can identify frank invasion and permit adequate treatment in a one-stage procedure. In early microinvasive disease, frozen section examination fails to detect the area of invasion but reliably detects clear resection margins.
Page 1 /180413
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.