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Search Results: 1 - 10 of 325614 matches for " Filipovi? Slavko S. "
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Influence of the applied pressure of processing upon bioactive components of diets made of feathers
Kormanjo? ?andor M.,FilipoviSlavko S.,Radovi? Vera A.,Okanovi? ?or?e G.
Hemijska Industrija , 2013, DOI: 10.2298/hemind120223044k
Abstract: The feathers gained by slaughtering fattening chickens can be processed into protein meal for feeding certain animals, as indicated by its chemical characteristics. However, raw feather proteins (keratin) are faintly digestible (cca. 19%), even inert in digestive tract. Digestion of feather proteins could be improved by hydrolysis (alkaline, enzymatic, microbiological or hydrothermal). Practically, hydrothermal processing of raw feathers is mostly applied. The influence of hydrothermal processing under the pressures of 3.0, 3.5 or 4.0 bar on the nutritive value of the resulting meal is presented in this paper. For the hydrolysis of raw feathers, semi continuous procedure was applied. Semi continuous procedure of feathers processing comprise hydrolysis of raw wet feathers followed by partial drying of hydrolyzed mass that has to be done in a hydrolyser with indirect heating. Continuous tubular dryer with recycled air was used during the final process of drying. Protein nitrogen decreased by 3.46% and 4.80% in comparison with total protein nitrogen content in raw feathers under the pressure of 3.0 and 3.5 bar, respectively. The highest applied hydrolysis pressure caused the greatest loss of protein nitrogen up to 9.52%. Hydrothermal hydrolysis under pressure has increased in vitro protein digestibility significantly. Under pressure of 3.0, 3.5 and 4.0 bar digestibility of proteins increasing from 19.01 to 76.39, 81.71 and 87.03%, respectively. Under pressure of 3.0, 3.5 and 4.0 bar cysteine content decreased from 6.44 to 4.17% (loss 35.25%), 3.94 (loss 38.825%) and to 3.75% (loss 41.77%), respectively. These decreases are statistically significant. It can be concluded that the hydrolysis carried out under the pressure of 3.5 bar, during the period of 25 minutes, and with the content of water in raw feathers of cca. 61% is the optimal technological process for converting raw feathers into diets for certain animal diets.
Influence of additive from sugar beet on white bread quality
Filipovi? Nada K.,Gyura Julianna F.,Filipovi? Jelena S.
Acta Periodica Technologica , 2004, DOI: 10.2298/apt0435025f
Abstract: The additive of acceptable sensory, physical and chemical and microbiological characteristics was made from cossettes. Great water binding capacity related to microcrystals of cellulose qualifies this additive as a desired one in bread making process. Bread was baked in the laboratory and patent flour was used. The additive with particles smaller than 95 (m was supplemented in the quantities of 2, 5 and 10%. The data related to the influence of the quantity of additive on white bread quality point that parallel to increasing the amount of the additive in the dough, yield of dough and bread were also increased. Negative effects are detected as volume depression and inferior bread crumb quality and altered crumb color. The decrease in bread quality is small if 2% of additive was applied, but significant with 5 and 10%. The bread freshness was highly graded 48 hours after baking due to the ability of the additive to retain water. On the whole, bread of superior quality supplemented by 5 and 10% of the additive from sugar beet fiber can be easily made by fortifying flour with gluten and by adding appropriate dough conditioner.
Precipitation of amorphous SiO2 particles and their properties
Musi?, S.;Filipovi?-Vincekovi?, N.;Sekovani?, L.;
Brazilian Journal of Chemical Engineering , 2011, DOI: 10.1590/S0104-66322011000100011
Abstract: the experimental conditions were optimized for the synthesis of amorphous sio2 particles by the reaction of neutralization of sodium silicate solution with h2so4 solution. amorphous sio2 particles were characterized by xrd, ft-ir, fe-sem, eds and microelectrophoresis. the amorphous peak was located at 2θ = 21.8o in the xrd pattern. primary sio2 particles were ~ 15 to ~ 30 nm in size and they aggregated into bigger particles. amorphous sio2 particles showed a specific surface area up to 130 m2g-1, dependent on the parameters of the precipitation process. the eds spectrum of amorphous sio2 particles did not show contamination with sulfate or other ions, which cannot be excluded in traces. phzpc =1.7 was obtained by microelectrophoresis.
Evidence of Molecular Adaptation to Extreme Environments and Applicability to Space Environments
Filipovi, M. D.,Ognjanovi?, S.,Ognjanovi?, M.
Serbian Astronomical Journal , 2008,
Abstract: This is initial investigation of gene signatures responsible for adapting microscopic life to the extreme Earth environments. We present preliminary results on identification of the clusters of orthologous groups (COGs) common to several hyperthermophiles and exclusion of those common to a mesophile (non-hyperthermophile): {it Escherichia coli (E. coli K12)}, will yield a group of proteins possibly involved in adaptation to life under extreme temperatures. Comparative genome analyses represent a powerful tool in discovery of novel genes responsible for adaptation to specific extreme environments. Methanogens stand out as the only group of organisms that have species capable of growth at 0D C ({it Metarhizium frigidum (M.~frigidum)} and {it Methanococcoides burtonii (M.~burtonii)}) and 110D C ({it Methanopyrus kandleri (M.~kandleri)}). Although not all the components of heat adaptation can be attributed to novel genes, the {it chaperones} known as heat shock proteins stabilize the enzymes under elevated temperature. However, highly conserved {it chaperons} found in bacteria and eukaryots are not present in hyperthermophilic Archea, rather, they have a unique {it chaperone TF55}. Our aim was to use software which we specifically developed for extremophile genome comparative analyses in order to search for additional novel genes involved in hyperthermophile adaptation. The followinghyperthermophile genomes incorporated in this software were used forthese studies: {it Methanocaldococcus jannaschii (M.~jannaschii), M.~kandleri, Archaeoglobus fulgidus (A.~fulgidus)} and threespecies of {it Pyrococcus}. Common genes were annotated and groupedaccording to their roles in cellular processes where such informationwas available and proteins not previously implicated in theheat-adaptation of hyperthermophiles were identified. Additionalexperimental data are needed in order to learn more about theseproteins. To address non-gene based components of thermaladaptation, all sequenced extremophiles were analysed for their GCcontents and aminoacid hydrophobicity. Finally, we develop a prediction model for optimal growth temperature.
Economic analysis of wheat production on family farms
Todorovi? Sa?a Z.,Filipovi? Nikola S.
Journal of Agricultural Sciences , 2010, DOI: 10.2298/jas1001079t
Abstract: Serbian agricultural producers are currently facing a large number of challenges which have a significant influence on their business activities. Continuous monitoring and evaluation of existing family farms business activities is the only way to improve their profitability and enhance competitiveness in such conditions. Bearing this in mind, the objective of this research is to emphasize an importance of the economic analysis of wheat production on family farms and to contribute successfully to the formulation of the answers to questions if and under which conditions the wheat production is profitable. In order to have a complete insight into investigated problem subject, investigations were carried out on selected family farms. Collected data were processed using calculation procedure for the purpose of determination of main economical indicators of the success of wheat production. Based on realized financial results it can be concluded that with the selling price of 10,000.00 diners per ton, only family farms which have achieved yield of over 7.5 t/ha with adequate level of investments are profitable. Since realized average yield of wheat on family farms in the Republic of Serbia in 2009 was 3.58 t/ha and level of investment necessary for realization of this yield, it is clear that the majority of family farms had loss in wheat production. The results of this study suggest that the economic status of the wheat production depends on the yield and achieved sales price, as well as on the amount of applied production factors and price level for their purchasing.
Influence of mechanical activation on microstructure and crystal structure of sintered MgO-TiO2 system
FilipoviS.,Obradovi? N.,Pavlovi? V.B.,Markovi? S.
Science of Sintering , 2010, DOI: 10.2298/sos100518002f
Abstract: Mixtures of MgO-TiO2 were mechanically activated using high-energy planetary ball mill during 5, 10, 20, 40, 80 and 120 minutes. Sintering process was preformed in air at 1100o-1400oC for 2h. The decrease in powder’s particle size was noticed as the time of mechanical activation increased and confirmed by particle size analyzer. XRD analyses were performed in order to acquire the information about phase composition. Different ratio mixtures of MgTiO3 and Mg2TiO4 are present within all sintered samples. The effect of tribophysical activation on microstructure was investigated by scanning electron microscopy. The differential thermal gravimetric analysis has been performed in order to investigate thermal behaviour of the mixtures.
The Regulation of Medicines in Croatia - a Contribution to Public Health
Tomi?, S,Filipovi? Su?i?, A,Ili? Martinac, A
Kemija u Industriji , 2010,
Abstract: The regulatory system for medicinal products includes the existence of a legislative framework and a medicines agency as the regulatory body. The legislative framework for medicinal products has been amended several times so as to align it with the EU acquis communautaire, where medicinal products represent one of the best regulated and aligned areas. For the purpose of regulating the Croatian medicines market, the Agency for Medicinal Products and Medical Devices was established in 2003 to implement the procedure of granting marketing authorisation for medicinal products, to supervise the adverse reactions of medicinal products, to conduct laboratory tests of the quality of medicines and vaccines sampled from the market, to issue licences for the manufacture and distribution of medicinal products, to monitor medicine consumption, and to inform about medicines and promote their rational use. Medical devices are regulated under a special act, and the Agency conducts entries into the register in that field and carries out vigilance over medical devices. In this way, products intended for health care on the Croatian market are of the appropriate quality, safety and efficacy, and are under the constant supervision of the competent body that assesses their risk-to-benefit ratio. Upon accession of the Republic of Croatia to full membership in the European Union, the Agency will be included in the European authorisation procedures for medicines, such as the centralised procedure in the European Medicines Agency (EMA), and above all, the mutual recognition procedure and decentralised procedure in which the role of the agencies of EU Member States is greater. This article gives an overview of the most important regulatory activities in the field of medicinal products, and the readiness of the Agency to function in the future integrated European regulatory area.
Changes in concentrations of sera proteins in war wound
Radakovi? Sonja S.,?urbatovi? Maja,Stankovi? Neboj?a,Filipovi? N.
Acta Chirurgica Iugoslavica , 2005, DOI: 10.2298/aci0501059r
Abstract: During the general reaction to trauma, substantional changes in protein composition of sera occur. The aim of the prospective study was to investigate net change in total protein and albumin concentrations, as well as albumin/ globulin ratio in sera of war casualties during the first 14 posttraumatic days, and to establish the correlation between these changes and severity of trauma. Subjects were 79 war casualties. Controls: 33 blood donors. Methods: Injury severity was determined according to ISS and blood samples were collected 12 hours after trauma, then on the 1st, 2nd, 5th and 14th posttraumatic day. In war casualties values of total protein and albumin concentrations and albumin/globulin ratio were significantly decreased. Minimal concentrations were measured on 2nd posttraumatic day (589.04 g/l for total proteins, p; 36.66.21 g/l for albumins, p) or on 5th day (0.860.2 for albumin/globulin ratio, p). Conclusions: During the acute-phase response to trauma, significant changes in concentration of total proteins, albumins and albumin/globulin ratio occur in sera of war casualties. These changes are the most prominent during the first 5 days, with tendency for normalization after that. Intensity of these changes depends of the severity of trauma.
Axillary recurrence after modified radical mastectomy
Karanikoli? Aleksandar,?or?evi? N.,FilipoviS.,Pe?i? M.
Acta Chirurgica Iugoslavica , 2005, DOI: 10.2298/aci0503039k
Abstract: Optimal management for axillary recurrence is poorly understood. The aim of this study was to evaluate the risk factors for overall survival in the patients with axillary recurrence. Data of 1098 patients were collected from breast cancer registers from Clinic for Oncology Ni between 1990- 1995. All patients underwent modified radical mastectomy. Axillary recurrence was diagnosed in 43(3.92%) patients. Most patients were presented with a localized, palpable axillary mass 30(69.77%). Cox multivariate analysis of prognostic factors for breast cancer-specific survival showed that node status HR 4.69 (1.50 to 14.72), tumor size HR 3.18 (0.90 to 11.26) and axillary radiotherapy HR 1.99 (0.69 to 5.75) had statistically significant effect on breast cancer mortality. Log-rank (54.21 p<0.001) analysis showed significant difference for overall survival among women with a axillary recurrence based on different cancer stages. Tumor size and node status were the most important prognostic factors in women with axillary recurrence.
Effect of NaCl on seed germination in some Centaurium Hill. Species (Gentianaceae)
?ivkovi? S.,Devi? M.,Filipovi? B.,Giba Z.
Archives of Biological Sciences , 2007, DOI: 10.2298/abs0703227z
Abstract: The influence of high NaCl concentrations on seed germination in both light and darkness was examined in the species Centaurium pulchellum, C. erythraea, C. littorale, C. spicatum, and C. tenuiflorum. Salt tolerance was found to depend on the life history of the seeds. To be specific, seeds of all five species failed to complete germination when exposed to continuous white light if kept all the time in the presence of 100-200 mM and greater NaCl concentrations. However, when after two weeks NaCl was rinsed from the seeds and the seeds were left in distilled water under white light for an additional two weeks, all species completed germination to a certain extent. The percent of germination not only depended on NaCl concentration in the prior medium, but was also species specific. Thus, seeds of C. pulchellum, C. erythraea, and C. littorale completed germination well almost irrespective of the salt concentration previously experienced. On the other hand, seeds of C. tenuiflorum completed germination poorly if NaCl concentrations in the prior media were greater than 200 mM. When seeds after washing were transferred to darkness for an additional 14 days, they failed to complete germination if previously imbibed on media containing NaCl concentrations greater than 400 mM. However, the seeds of all species, even if previously imbibed at 800 mM NaCl, could be induced to complete germination in darkness by 1 mM gibberellic acid. .
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