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Search Results: 1 - 10 of 132545 matches for " Filgueiras Danilo V "
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Atypical Mucocutaneous Leishmaniasis Caused by Leishmania braziliensis in an Acquired Immunodeficiency Syndrome Patient: T-cell Responses and Remission of Lesions Associated with Antigen Immunotherapy
Da-Cruz Alda M,Filgueiras Danilo V,Coutinho Ziadir,Mayrink Wilson
Memórias do Instituto Oswaldo Cruz , 1999,
Abstract: An atypical case of acquired immunodeficiency syndrome-associated mucocutaneous lesions due to Leishmania braziliensis is described. Many vacuolated macrophages laden with amastigote forms of the parasite were found in the lesions. Leishmanin skin test and serology for leishmaniasis were both negative. The patient was resistant to therapy with conventional drugs (antimonial and amphotericin B). Interestingly, remission of lesions was achieved after an alternative combined therapy of antimonial associated with immunotherapy (whole promastigote antigens). Peripheral blood mononuclear cells were separated and stimulated in vitro with Leishmania antigens to test the lymphoproliferative responses (LPR). Before the combined immunochemotherapy, the LPR to leishmanial antigens was negligible (stimulation index - SI=1.4). After the first course of combined therapy it became positive (SI=4.17). The antigen responding cells were predominantly T-cells (47.5%) most of them with CD8+ phenotype (33%). Very low CD4+ cells (2.2%) percentages were detected. The increased T-cell responsiveness to leishmanial antigens after combined therapy was accompanied by interferon-g (IFN-g) production as observed in the cell culture supernatants. In this patient, healing of the leishmaniasis lesions was associated with the induction of a specific T-cell immune response, characterized by the production of IFN-g and the predominance of the CD8+ phenotype among the Leishmania-reactive T-cells.
Atypical Mucocutaneous Leishmaniasis Caused by Leishmania braziliensis in an Acquired Immunodeficiency Syndrome Patient: T-cell Responses and Remission of Lesions Associated with Antigen Immunotherapy
Da-Cruz, Alda M;Filgueiras, Danilo V;Coutinho, Ziadir;Mayrink, Wilson;Grimaldi Jr, Gabriel;De Luca, Paula M;Mendon?a, Sergio CF;Coutinho, Sergio G;
Memórias do Instituto Oswaldo Cruz , 1999, DOI: 10.1590/S0074-02761999000400020
Abstract: an atypical case of acquired immunodeficiency syndrome-associated mucocutaneous lesions due to leishmania braziliensis is described. many vacuolated macrophages laden with amastigote forms of the parasite were found in the lesions. leishmanin skin test and serology for leishmaniasis were both negative. the patient was resistant to therapy with conventional drugs (antimonial and amphotericin b). interestingly, remission of lesions was achieved after an alternative combined therapy of antimonial associated with immunotherapy (whole promastigote antigens). peripheral blood mononuclear cells were separated and stimulated in vitro with leishmania antigens to test the lymphoproliferative responses (lpr). before the combined immunochemotherapy, the lpr to leishmanial antigens was negligible (stimulation index - si=1.4). after the first course of combined therapy it became positive (si=4.17). the antigen responding cells were predominantly t-cells (47.5%) most of them with cd8+ phenotype (33%). very low cd4+ cells (2.2%) percentages were detected. the increased t-cell responsiveness to leishmanial antigens after combined therapy was accompanied by interferon-g (ifn-g) production as observed in the cell culture supernatants. in this patient, healing of the leishmaniasis lesions was associated with the induction of a specific t-cell immune response, characterized by the production of ifn-g and the predominance of the cd8+ phenotype among the leishmania-reactive t-cells.
A method for solving nonlinear differential equations: an application to $λφ^4$ model
Danilo V. Ruy
Physics , 2014,
Abstract: Recently, it has been great interest in the development of methods for solving nonlinear differential equations directly. Here, it is shown an algorithm based on Pad\'e approximants for solving nonlinear partial differential equations without requiring a one-dimensional reduction. This method is applied to the $\lambda\phi^4$ model in 4 dimensions and new solutions are obtained.
On the mKdV-Liouville hierarchy and its self-similarity reduction
Danilo V. Ruy
Physics , 2014, DOI: 10.1016/j.cnsns.2014.05.011
Abstract: Integrable mixed models have been used as a generalization of traditional integrable models. However, a map from a traditional integrable model to a mixed integrable model is not well understood yet. Here, it is studied the relation between the mKdV-Liouville hierarchy and the mKdV hierarchy by employing an extended version of the modified truncation approach. This paper shows some solutions for the mKdV-Liouville hierarchy constructed from the soliton solutions of the mKdV hierarchy. The last section deals with the possibility of define new transcendental functions from the self-similarity reduction of the mKdV-Liouville hierarchy.
Zero Curvature and generalization of Painlevé equation from AKNS/Lund-Regge model
Danilo V. Ruy,Genilson R. de Melo
Physics , 2012,
Abstract: We explain the relation between the mixed mKdV/sinh-Gordon model and the Kudryashov's equation. Then, we use the mixed AKNS/Lund-Regge model to find a system of ODEs which is candidate to define a new transcendental function. We also applied the perturbative Painlev\'e test and presented the local representation for the solution of the system.
Simulation and Control of Turbulence at Tokamaks with Artificial Intelligence Methods  [PDF]
Danilo Rastovic
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.312234
Abstract: The control of turbulence at tokamaks is very complex problem.The idea is to apply the fuzzy Markovian processes and fuzzy Brownian motions as good approximation of general robust drift kinetic equation. It is obtained by using the artificial neural networks for solving of appropriate advanced control problem. The proof of the appropriate theorem is shown.
Over and Undershot Waterwheels in the 18th Century. Science-Technology Controversy  [PDF]
Danilo Capecchi
Advances in Historical Studies (AHS) , 2013, DOI: 10.4236/ahs.2013.23017
Abstract: The present paper concerns the development of theory and experiments on water wheels in the 18th cen- tury. At that time, as a result of a growing demand for energy, a better understanding of the functioning of watermills, even at the theoretical level, was required in order to improve their efficiency. A hint about the evolution of the theory of wheels in the 19th century is reported also. We have tried to clarify the role played by some protagonists as Antoine Parent, Jean-Charles de Borda and John Smeaton. Their role has not been fully recognised even in contemporary studies. Then some considerations are developed on the relationships between science and technology on this particular subject, concluding that it was a happy and well-balanced marriage.
Epistemology of Greek Harmonics  [PDF]
Danilo Capecchi
Advances in Historical Studies (AHS) , 2015, DOI: 10.4236/ahs.2015.43014
Abstract: Greek harmonics is the theory of the organization of notes with respect to the highness or lowness of their pitches. This was a mathematical science, a thorough knowledge of which was not necessary for the professional musician and was thus cultivated essentially by mathematicians and philosophers. For them, harmonics was mixed mathematics, the mix being between experimental assertions derived from hearing and propositions derived from reason, that was, mathematics. This classification was maintained through the Middle Ages and the Renaissance. Despite the important role played by harmonics in ancient science, little consideration has been given by historians of science. This study shows that harmonics merits a careful study and that its methods are the same as other sciences. Particular attention was devoted to Ptolemy who applied the same approach to harmonics as he did to astronomy, astrology and geography.
Experiments, Mathematics and Principles of Natural Philosophy in the Epistemology of Giovanni Battista Baliani  [PDF]
Danilo Capecchi
Advances in Historical Studies (AHS) , 2017, DOI: 10.4236/ahs.2017.62006
Abstract: The epistemology of Giovanni Battista Baliani, a leading 17th century Italian scientist, is the focus of this article. In his treatise on motion, De motu naturali gravium solidorum (1638), Baliani’s epistemology was grounded on empirical principlesthe law of the pendulum essentiallyin the footsteps of the old mixed mathematics. In a new edition, De motu naturali gravium solidorum et liquidorum (1646), Baliani changed his approach and grounded his epistemology on principles of natural philosophy with a metaphysical and not empirical evidence. An analysis of Baliani’s writings reveals a tension between his empiricist philosophy, which he maintained throughout his life, and his mathematical approach, which was still based on experience; but on an experience derived from measurements and intrinsically affected by errors, it was hence uncertain. A comparison with Galileo’s epistemology is also made to better understand trends in mathematical physics at the end of the 1600’s.
Estudo comparativo entre a resistência das suturas manual e mecanica do coto br?nquico em c?es submetidos a pneumonectomia esquerda
Bof, Ant?nio Mauro;Rapoport, Abr?o;Paulo, Danilo Nagib Salom?o;Leiro, Luiz Carlos Filgueiras;Gomes, Márcio Rogério Alcalá;Pando-Serrano, Roberto Ruben;
Jornal Brasileiro de Pneumologia , 2007, DOI: 10.1590/S1806-37132007000200007
Abstract: objective: to compare the resistance of manual suture with that of mechanical suture immediately after the suture of the left bronchial stump of dogs submitted to pneumonectomy. methods: a total of 15 mixed-breed dogs of both genders, each weighing between 8 and 23 kg, were randomly divided into 2 groups. in group i (n = 7), the bronchial stump was sutured manually (the sweet method) and, in group ii (n = 8), it was stapled. immediately after the closure of the bronchial stump, the intratracheal pressure was progressively increased in a controlled manner. results: the mean rupture pressure of the bronchial stump suture line was 33.71 mmhg in group i and 89.87 mmhg in group ii (p < 0.01). conclusion: these data allowed us to conclude that mechanical suture of the bronchial stump, submitted to pressure immediately after closure, is more resistant than is manual suture in dogs submitted to pneumonectomy.
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