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Search Results: 1 - 10 of 79319 matches for " Fernando; González Z "
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LA SIMULACIóN COMO APOYO PARA LA COMPRENSIóN DE LOS SISTEMAS DE PRODUCCIóN DE POZOS PETROLEROS
FERNANDO ENRIQUE CALVETE GONZáLEZ,FERNANDO RUíZ DíAZ,ELIéCER PINEDA BALLESTEROS
Scientia Et Technica , 2008,
Abstract: La idea que guía esta propuesta es que el uso del modelado y la simulación pueden contribuir en la comprensión de los fenómenos físicos que gobiernan el fenómeno de producción de pozos petroleros y una vez conseguido, el futuro ingeniero de producción tendrá más y mejores herramientas para lograr procesos excelentes de producción. La propuesta comprende la modelación del fenómeno que incluye al yacimiento, el pozo y las facilidades de transporte tomando como referente teórico la ley de Darcy. Una vez modelado el fenómeno se construye un micromundo que facilite la experimentación y el análisis mediante la construcción de modelos
Unraveling the evolutionary history of the phosphoryl-transfer chain of the phosphoenolpyruvate:phosphotransferase system through phylogenetic analyses and genome context
I?aki Comas, Fernando González-Candelas, Manuel Zú?iga
BMC Evolutionary Biology , 2008, DOI: 10.1186/1471-2148-8-147
Abstract: We have analyzed the evolutionary history of the PTS phosphoryl transfer chain (PTS-ptc) components in 222 complete genomes by combining phylogenetic methods and analysis of genomic context. Phylogenetic analyses alone were not conclusive for the deepest nodes but when complemented with analyses of genomic context and functional information, the main evolutionary trends of this system could be depicted.The PTS-ptc evolved in bacteria after the divergence of early lineages such as Aquificales, Thermotogales and Thermus/Deinococcus. The subsequent evolutionary history of the PTS-ptc varied in different bacterial lineages: vertical inheritance and lineage-specific gene losses mainly explain the current situation in Actinobacteria and Firmicutes whereas horizontal gene transfer (HGT) also played a major role in Proteobacteria. Most remarkably, we have identified a HGT event from Firmicutes or Fusobacteria to the last common ancestor of the Enterobacteriaceae, Pasteurellaceae, Shewanellaceae and Vibrionaceae. This transfer led to extensive changes in the metabolic and regulatory networks of these bacteria including the development of a novel carbon catabolite repression system. Hence, this example illustrates that HGT can drive major physiological modifications in bacteria.The phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) was originally described as a sugar phosphorylation system [1] and it represents hitherto the only example of group-translocating transport systems [2]. The PTS couples solute transport to its phosphorylation at the expense of phosphoenolpyruvate (PEP) and it also plays a central role in the regulation of a number of cell processes in some bacteria [3-6]. This system consists of general cytoplasmic energy-coupling proteins, enzyme I (EI) and HPr, and specific enzyme II complexes, which catalyze the uptake and phosphorylation of solutes [3,7]. In turn, enzyme II complexes consist of three functional subunits, IIA, IIB and IIC, although
Evolutionary history of the OmpR/IIIA family of signal transduction two component systems in Lactobacillaceae and Leuconostocaceae
Manuel Zú?iga, Ciara Gómez-Escoín, Fernando González-Candelas
BMC Evolutionary Biology , 2011, DOI: 10.1186/1471-2148-11-34
Abstract: The genomes of 19 strains belonging to 16 different species have been analyzed. The number of TCS encoded by the strains considered in this study varied between 4 in Lactobacillus helveticus and 17 in Lactobacillus casei. The OmpR/IIIA family was the most prevalent in Lactobacillaceae accounting for 71% of the TCS present in this group. The phylogenetic analysis shows that no new TCS of this family has recently evolved in these Lactobacillaceae by either lineage-specific gene expansion or domain shuffling. Furthermore, no clear evidence of non-orthologous replacements of either RR or HK partners has been obtained, thus indicating that coevolution of cognate RR and HKs has been prevalent in Lactobacillaceae.The results obtained suggest that vertical inheritance of TCS present in the last common ancestor and lineage-specific gene losses appear as the main evolutionary forces involved in their evolution in Lactobacillaceae, although some HGT events cannot be ruled out. This would agree with the genomic analyses of Lactobacillales which show that gene losses have been a major trend in the evolution of this group.Two component systems (TCS) are widespread signal transduction pathways mainly found in bacteria where they play a major role in adaptation to changing environmental conditions. Nevertheless, they can also be found in some eukaryotes and archaea. Numerous studies have shown the involvement of TCS in a broad range of adaptive processes such as sporulation, nitrogen regulation, phosphate regulation, cell envelope stress response, pathogenicity, motility, etc. [1]. TCS typically consist of a sensor histidine kinase (HK), usually membrane-bound, and a cytoplasmic response regulator (RR). HKs and RRs are modular proteins containing homologous and heterologous domains [2,3]. The homologous domains, kinase domain and H-box in HKs and receptor domain in RR, are involved in the phosphotransfer reaction whereas the heterologous domains, sensor (HKs) and effector (RR) doma
PASTA UNTABLE DE PAVO ENRIQUECIDA CON FIBRAS, VITAMINAS Y MINERALES ANTIOXIDANTES COMO INGREDIENTES FUNCIONALES PARA EL ADULTO MAYOR
Garrido B,Fernando; González Z,Stephany; Dondero C,Marta; Wittig de Penna R,Emma;
Revista chilena de nutrición , 2010, DOI: 10.4067/S0717-75182010000300011
Abstract: a spread for the elderly with turkey, fibers (insulin and oligofructose), anti-oxidant vitamins (a and e) and minerals (selenium and zinc) has been developed. the methodology of taguchi was used for the optimization of the formulation, considering control factors such as pig butter, hydrated insulin, lactonal, salt, oregano/pepper, garlic and ice. experimental designs l8 (27) and l9 (34) were used, and sensorial assessments were made. the optimized formulation obtained a value of4.51 (greater than "good"). the low fat and calorie levels as well as the smooth and pleasant texture stand out in the product. furthermore, it has been shown that the product is apt and safe for consumption. the spread maintained an optimal sensorial and sanitary quality during storage for 28 days under refrigeration. elderly showed a 90% of acceptance and a high preference by the spread. therefore, the methodology of taguchi optimized the spread, making it a good alternative of food for the elderly.
Histiocitosis de células de Langerhans pulmonar: Caso clínico
OSSES A,RODRIGO; GONZáLEZ B,SERGIO; AGUIRRE Z,MARCIA; SALDíAS P,FERNANDO;
Revista médica de Chile , 2011, DOI: 10.4067/S0034-98872011000200014
Abstract: adult pulmonary langerhans cell histiocytosis (plch) is a rare disorder of unknown etiology that occurs predominantly in young smokers, with an incidence peak at 20-40 years of age. in adults, pulmonary involvement with langerhans cell histiocytosis usually occurs as a single-organ disease and is characterized by focal langerhans cell granulomas infiltrating and destroying distal bronchioles. we report a 23-year-old asymptomatic male smoker with a non specific interstitial infiltrate found in preventive chest x ray examination. a high resolution chest ct scan showed multiple cystic structures predominating in the upper lobes, with small centrilobular nodules. a transbronchial biopsy showed a lymphocytic lung infiltrate with langerhans cells. a surgical biopsy confirmed the diagnosis of pulmonary langerhans cell histiocytosis. after six months of follow up, the patient is in good conditions.
PASTA UNTABLE DE PAVO ENRIQUECIDA CON FIBRAS, VITAMINAS Y MINERALES ANTIOXIDANTES COMO INGREDIENTES FUNCIONALES PARA EL ADULTO MAYOR TURKEY SPREAD WITH FIBER, ANTI-OXIDANT VITAMINS AND MINERALS AS FUNCTIONAL INGREDIENTS FOR ELDERLY PEOPLE
Fernando Garrido B,Stephany González Z,Marta Dondero C,Emma Wittig de Penna R
Revista Chilena de Nutricíon , 2010,
Abstract: Se desarrolló una pasta untable destinada al adulto mayor con pavo, fibras solubles (inulina y oligofructosa), vitaminas (A y E) y minerales antioxidantes (selenio y zinc). La formulación se optimizó con la metodología de Taguchi, considerando como factores de control: manteca de cerdo, inulina hidratada, emulsionante, sal, orégano/pimienta, ajo y hielo. Se utilizaron los dise os experimentales L8(27) y L9(34) y se realizaron evaluaciones sensoriales, obteniendo la formulación optimizada un puntaje de 4,51 (superior a "bueno"). Del producto destacó el bajo nivel de lípidos y calorías, la textura suave-agradable y se demostró que el producto es apto y seguro para el consumo, manteniendo su calidad sensorial y sanitaria durante 28 días de almacenamiento en refrigeración. El adulto mayor mostró un 90% de aceptación y alta preferencia por la pasta. Por lo tanto, la metodología de Taguchi logró optimizar la pasta untable, constituyendo una buena alternativa de alimento para el adulto mayor. A spread for the elderly with turkey, fibers (insulin and oligofructose), anti-oxidant vitamins (A and E) and minerals (selenium and zinc) has been developed. The methodology of Taguchi was used for the optimization of the formulation, considering control factors such as pig butter, hydrated insulin, lactonal, salt, oregano/pepper, garlic and ice. Experimental designs L8 (27) and L9 (34) were used, and sensorial assessments were made. The optimized formulation obtained a value of4.51 (greater than "good"). The low fat and calorie levels as well as the smooth and pleasant texture stand out in the product. Furthermore, it has been shown that the product is apt and safe for consumption. The spread maintained an optimal sensorial and sanitary quality during storage for 28 days under refrigeration. Elderly showed a 90% of acceptance and a high preference by the spread. Therefore, the methodology of Taguchi optimized the spread, making it a good alternative of food for the elderly.
Histiocitosis de células de Langerhans pulmonar: Caso clínico Adult pulmonary Langerhans cell histiocytosis: Report of one case
RODRIGO OSSES A,SERGIO GONZáLEZ B,MARCIA AGUIRRE Z,FERNANDO SALDíAS P
Revista médica de Chile , 2011,
Abstract: Adult pulmonary Langerhans cell histiocytosis (PLCH) is a rare disorder of unknown etiology that occurs predominantly in young smokers, with an incidence peak at 20-40 years of age. In adults, pulmonary involvement with Langerhans cell histiocytosis usually occurs as a single-organ disease and is characterized by focal Langerhans cell granulomas infiltrating and destroying distal bronchioles. We report a 23-year-old asymptomatic male smoker with a non specific interstitial infiltrate found in preventive chest X ray examination. A high resolution chest CT scan showed multiple cystic structures predominating in the upper lobes, with small centrilobular nodules. A transbronchial biopsy showed a lymphocytic lung infiltrate with Langerhans cells. A surgical biopsy confirmed the diagnosis of pulmonary Langerhans cell histiocytosis. After six months of follow up, the patient is in good conditions.
La cuantificación no invasiva del estrés parietal sistólico del ventrículo izquierdo en pacientes con insuficiencia cardíaca y su aplicación clínica
Guadalajara Boo, José Fernando;González Zárate, Jaime;Bucio Reta, Eduardo;Pérez, Patricia;Cué Carpio, Ramón José;
Archivos de cardiología de México , 2007,
Abstract: the purpose of this study is to calculate non invasivelly left ventricular systolic wall stress by echocardiography in patients with primary heart failure, and compare the results with those obtained in parients with overloaded heart failure, diastolic dysfunction by inapropiatte hypertrophy, with normal ejection fraction and people with normal heart, there stablish the value of the results in clinical settings. we studied 33 patients with heart failure by dilated cardiomyopathy. there was no significant association between the systolic wall stress and the ejection fraction, fractional shortening, dp/dt or left ventricular mass in this group of study. there was a significant association between systolic h/r ratio and the systolic wall stress. this study shows that in primary heart failure the afterload increases and has inverse relationship with ejection fraction (r = 0.86); but, when heart failure obey to an excessive overload exists an exquisite inverse relationship between systolic wall stress and ejection fraction (r = 0.93). the excessive hypertrophy (inappropriate) reduces the systolic wall stress but causes diastolic dysfunction. the increase of systolic wall stress in aortic regurgitation with normal ventricular performance is responsible of adequate left ventricular hypertrophy, by other means, in mitral insufficiency the presence of low or normal systolic wall stress does not induce left ventricular hypertrophy, then diameter increases and the hypertrophy is inadequate, despite this, left ventricular function is normal.
Consenso de diagnóstico y manejo de los nódulos tiroideos no palpables
Campusano M,Claudia; Bello M,Fernando; González E,Renato; Lam E,José; Liberman G,Claudio; Munizaga C,Fernando; Sapunar Z,Jorge; Wohllk G,Nelson;
Revista médica de Chile , 2004, DOI: 10.4067/S0034-98872004001000014
Abstract: with the availability of new diagnostic techniques, numerous alterations are found, whose real importance for health is uncertain. the term ?incidentalomas?, is used for non apparent tumors found in diagnostic procedures. in endocrinology, the incidental finding of thyroid nodules is common. the occurrence of those incidental nodules requires a review of the ?classical? statements for the management of palpable nodules. the most important issue is to rule out the presence of cancer. the chilean society of endocrinology, metabolism and nutrition appointed a group of experts to generate a consensus on the management of non palpable nodules. these experts reviewed international literature, and the local experience, analyzed the value of thyroid ultrasound examination and the efficiency of fine needle aspiration biopsy. this consensus is a clinical guide for the management of non palpable thyroid nodules, considering that a unique and optimal approach is still lacking (rev méd chile 2004; 132: 1249-55)
Health Status of Urban Medium-Low-Income Elderly at the Community  [PDF]
Lilia Cárdenas-Ibarra, Jesús Z. Villarreal-Pérez, Raúl Fernando Gutiérrez Herrera, Perla Alejandra Mellado-Urbina, Ana Laura Turner-Llaguno, Adolfo Montemayor-Alatorre, José Carlos Lira-Castillo, Fernando J. Lavalle González
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2018, DOI: 10.4236/ojemd.2018.83011
Abstract: Background: Nonagenarians are uncommon in our population. The study aim was to profile physical mobility, declared health problems, hypertension and diabetes frequency, awareness, treated and good control in urban low-income elders. Method: The study had cross-sectional design in population sample. Subjects were urban men and women older than 59 years at the medium low income stratum at a developing country. Survey was carried out from October 2008 to October 2009. All elder dwellers in randomly selected houses were surveyed; clinical exam after consent. Good Control: Systolic/Diastolic <135/<85 mmHg, and HbA1c < 7% for diabetes. Results: There were 162 elders, 53 (32.7%) were male, 99 (61.1%) were younger than 70 years. Forty nine (30.2%) had impaired mobility; among them 20 (55.6%) were bed or home restricted, and 29 (44.4%) needed help to go out. Unstable health condition was found in 36 (22.2%), with significantly more men 19 (52.8%) vs 34 (27.0%), X2 = 8.5, df1, P < 0.005; and impaired mobility 32 (88.9%) vs 17 (13.5%), P < 0.001; but similar age 69.2 ± 7.7 vs 68.3 ± 7.3, t = 0.62, df 160, P > 0.05. The frequency, proportions for: known diagnosis, on treatment, and good control were 75 (69.4%), 55 (73.3%), 45 (60.0%) and 12 of 45 (26.7%) for hypertension; 53 (49.1%), 47 (88.7%), 42 (79.2%) and 9 of 42 (21.4%) for diabetes. The most frequent unstable conditions were cardiovascular. Conclusions: Data suggest unstable health no association with the oldest old. The small proportion in good control of Diabetes and/or hypertension could explain the large frequency of elders with unstable health and prevention of reaching nonagenarian age.
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