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Search Results: 1 - 10 of 23981 matches for " Fernando Casals-Seoane "
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Tenofovir treatment of the severe acute hepatitis B Tratamiento con tenofovir de la hepatitis aguda B de evolución grave
Fernando Casals-Seoane,Beatriz Arberas-Díez,Luisa García-Buey
Revista Espa?ola de Enfermedades Digestivas , 2013,
Abstract:
Textile Electrodes for EEG Recording — A Pilot Study
Johan L?fhede,Fernando Seoane,Magnus Thordstein
Sensors , 2012, DOI: 10.3390/s121216907
Abstract: The overall aim of our research is to develop a monitoring system for neonatal intensive care units. Long-term EEG monitoring in newborns require that the electrodes don’t harm the sensitive skin of the baby, an especially relevant feature for premature babies. Our approach to EEG monitoring is based on several electrodes distributed over the head of the baby, and since the weight of the head always will be on some of them, any type of hard electrode will inevitably cause a pressure-point that can irritate the skin. Therefore, we propose the use of soft conductive textiles as EEG electrodes, primarily for neonates, but also for other kinds of unobtrusive long-term monitoring. In this paper we have tested two types of textile electrodes on five healthy adults and compared them to standard high quality electrodes. The acquired signals were compared with respect to morphology, frequency distribution, spectral coherence, correlation and power line interference sensitivity, and the signals were found to be similar in most respects. The good measurement performance exhibited by the textile electrodes indicates that they are feasible candidates for EEG recording, opening the door for long-term EEG monitoring applications.
Protective effect of butylated hydroxytoluene (BHT) against the clastogenic acitivity of cadmium chloride and potassium dichromate in hamster ovary cells
Grillo, Claudia A.;Seoane, Analía I.;Dulout, Fernando N.;
Genetics and Molecular Biology , 1999, DOI: 10.1590/S1415-47571999000100012
Abstract: the effect of butylated hydroxytoluene (bht), a widely used food additive, on chromosomal alterations induced by cadmium chloride (cc) and potassium dichromate (pd) in chinese hamster ovary (cho) cells was studied both at metaphase and anaphase-telophase. cho cells were cultured for 15-16 h in the presence of pd (6.0, 9.0 or 12.0 mm), bht (1.0 mg/ml), or pd plus bht as well as cc (0.5, 1.0 and 2.0 mm), bht or cc plus bht for the analysis of chromosomal aberrations. to perform the anaphase-telophase test, cells were cultured in cover glasses and treated 8 h before fixation with the same chemicals. an extra dose of cc (4 mm) was used in this test. both metal salts significantly increased chromosomal aberration frequencies in relation to untreated controls, and to dmso- and bht-treated cells. post-treatment with bht decreased the yield of chromosomal damage in relation to treatments performed with cc and pd. however, chromosomal aberration frequencies were significantly higher than those of the controls. in the anaphase-telophase test, cc significantly increased the yield of lagging chromosomes with the four doses employed and the frequency of lagging fragments with the highest dose. in combined treatments of cc and bht, frequencies of the two types of alterations decreased significantly in relation to the cells treated with cc alone. no significant variation was found in the frequencies of chromatin bridges. significant increases of numbers of chromatin bridges, lagging chromosomes and lagging fragments were found in cells treated with pd. the protective effect of bht in combined treatments was evidenced by the significant decrease of chromatid bridges and lagging chromosomes in relation to pd-treated cells. whereas bht is able to induce chromosomal damage, it can also protect against oxidative damage induced by other genotoxicants.
Cole Parameter Estimation from the Modulus of the Electrical Bioimpeadance for Assessment of Body Composition. A Full Spectroscopy Approach.
Ruben Buendia,Roberto Gil-Pita,Fernando Seoane
Journal of Electrical Bioimpedance , 2011, DOI: 10.5617/jeb.197
Abstract: Activities around applications of Electrical Bioimpedance Spectroscopy (EBIS) have proliferated in the past decade significantly. Most of these activities have been focused in the analysis of the EBIS measurements, which eventually might enable novel applications. In Body Composition Assessment (BCA) the most common analysis approach currently used in EBIS is based on the Cole function, which most often requires curve fitting. One of the most implemented approaches for obtaining the Cole parameters is performed in the impedance plane through the geometrical properties that the Cole function exhibit in such domain as depressed semi-circle. To fit the measured impedance data to a semi-circle in the impedance plane, obtaining the Cole parameters in an indirect and sequential manner has several drawbacks. Applying a Non-Linear Least Square (NLLS) iterative fitting on the spectroscopy measurement, obtains the Cole parameters considering the frequency information contained in the measurement. In this work, from experimental total right side EBIS measurements, the BCA parameters have been obtained to assess the amount and distribution of whole body fluids. The values for the BCA parameters have been obtained using values for the Cole parameters estimated with both approaches: circular fitting on the impedance plane and NLLS impedance-only fitting. The comparison of the values obtained for the BCA parameters with both methods confirms that the NLLS impedance-only is an effective alternative as Cole parameter estimation method in BCA from EBIS measurements. Using the modulus of the Cole function as the model for the fitting would eliminate the need for performing a phase detection in the acquisition process, simplifying the hardware specifications of the measurement instrumentation when implementing a bioimpedance spectrometer. doi:10.5617/jeb.197 J Electr Bioimp, vol. 2, pp. 72-78, 2011
Protective effect of butylated hydroxytoluene (BHT) against the clastogenic acitivity of cadmium chloride and potassium dichromate in hamster ovary cells
Grillo Claudia A.,Seoane Analía I.,Dulout Fernando N.
Genetics and Molecular Biology , 1999,
Abstract: The effect of butylated hydroxytoluene (BHT), a widely used food additive, on chromosomal alterations induced by cadmium chloride (CC) and potassium dichromate (PD) in Chinese hamster ovary (CHO) cells was studied both at metaphase and anaphase-telophase. CHO cells were cultured for 15-16 h in the presence of PD (6.0, 9.0 or 12.0 mM), BHT (1.0 mg/ml), or PD plus BHT as well as CC (0.5, 1.0 and 2.0 mM), BHT or CC plus BHT for the analysis of chromosomal aberrations. To perform the anaphase-telophase test, cells were cultured in cover glasses and treated 8 h before fixation with the same chemicals. An extra dose of CC (4 mM) was used in this test. Both metal salts significantly increased chromosomal aberration frequencies in relation to untreated controls, and to DMSO- and BHT-treated cells. Post-treatment with BHT decreased the yield of chromosomal damage in relation to treatments performed with CC and PD. However, chromosomal aberration frequencies were significantly higher than those of the controls. In the anaphase-telophase test, CC significantly increased the yield of lagging chromosomes with the four doses employed and the frequency of lagging fragments with the highest dose. In combined treatments of CC and BHT, frequencies of the two types of alterations decreased significantly in relation to the cells treated with CC alone. No significant variation was found in the frequencies of chromatin bridges. Significant increases of numbers of chromatin bridges, lagging chromosomes and lagging fragments were found in cells treated with PD. The protective effect of BHT in combined treatments was evidenced by the significant decrease of chromatid bridges and lagging chromosomes in relation to PD-treated cells. Whereas BHT is able to induce chromosomal damage, it can also protect against oxidative damage induced by other genotoxicants.
Democracia, Movimientos Sociaies y Crisis Económica en Casta Rica.
Fernando DíAZ ORUETA,María Luisa LOURéS SEOANE
América Latina Hoy , 2009,
Abstract: RESUMEN: Los autores parten de analizar el rol de los movimientos sociales en el surgimiento de la democracia en Costa Rica en los atlos 30 y 40, luego analizan el proceso de la cooptacián de los movimientos sociales por el Estado democrático y la consiguiente pérdida de vitalidad y autonomía de aquellos. Finalmente plantean el problema de que si bien esto no ha debilitado la confianza en las instituciones democráticas sí ha debilitado el contenido social de la democracia. ABSTRACT: The authors analyze the role of the socíal movements in the emergence of the democracy in Costa Rica in the 30's and 40's. The they analyze the process of the democratic State's cooptation of the social movements and the next lost of vitality and autonomy of these. Finally, the focused in the problem of the weakening of the confidence in the democratic institutions and the weakening of the social contents of the democracy.
Stroke Damage Detection Using Classification Trees on Electrical Bioimpedance Cerebral Spectroscopy Measurements
Seyed Reza Atefi,Fernando Seoane,Thorleif Thorlin,Kaj Lindecrantz
Sensors , 2013, DOI: 10.3390/s130810074
Abstract: After cancer and cardio-vascular disease, stroke is the third greatest cause of death worldwide. Given the limitations of the current imaging technologies used for stroke diagnosis, the need for portable non-invasive and less expensive diagnostic tools is crucial. Previous studies have suggested that electrical bioimpedance (EBI) measurements from the head might contain useful clinical information related to changes produced in the cerebral tissue after the onset of stroke. In this study, we recorded 720 EBI Spectroscopy (EBIS) measurements from two different head regions of 18 hemispheres of nine subjects. Three of these subjects had suffered a unilateral haemorrhagic stroke. A number of features based on structural and intrinsic frequency-dependent properties of the cerebral tissue were extracted. These features were then fed into a classification tree. The results show that a full classification of damaged and undamaged cerebral tissue was achieved after three hierarchical classification steps. Lastly, the performance of the classification tree was assessed using Leave-One-Out Cross Validation (LOO-CV). Despite the fact that the results of this study are limited to a small database, and the observations obtained must be verified further with a larger cohort of patients, these findings confirm that EBI measurements contain useful information for ? assessing on the health of brain tissue after stroke and supports the hypothesis that classification features based on Cole parameters, spectral information and the geometry of EBIS measurements are useful to differentiate between healthy and stroke damaged brain tissue.
‘Corrandescola’: del cant a la improvisació poètica / ‘Corrandescola’: Du chant à l’improvisation poétique Corrandescola’: From song to poetic improvisation ‘Corrandescola’: del canto a la improvisación poética
Albert Casals
Temps d'Educació , 2012,
Abstract: Glosa o can ó improvisada és el nom d’una activitat comunicativa que es dóna en el si d’una comunitat i que es vehicula a través de versos improvisats que es canten sobre melodies d’arrel tradicional. En la primera part de l’article s’aborda la configuració textual, musical i escènica d’aquest gènere poèticomusical per presentar a continuació el projecte Corrandescola. Es mostra com aquest projecte ha desenvolupat una proposta didàctica que s’ha dut a terme en diverses escoles de Catalunya i que es fonamenta en les possibilitats educatives de la can ó improvisada. A l’última part de l’article es plantegen les oportunitats i limitacions de la proposta en relació al descobriment poètic per part de l’alumnat de cicle superior de Primària. Una de les conclusions que se n’extreu és que la can ó improvisada pot esdevenir una forma efica d’acostament a la poesia gràcies al fet que es basa en un paradigma comunicatiu altament significatiu i motivador des de la perspectiva de l’alumnat participant. ____________________________________________________ La glosa ou chanson improvisée est une activité communicative qui se produit au sein d'une communauté et qui consiste à l’interprétation chantée de vers improvisés dont les mélodies sont de racine traditionnelle. La première partie de cet article présente la configuration textuelle, musicale et théatrale de ce genre poétique-musical puis continue avec la présentation du projet Corrandescola. Nous montrons comment autour de ce projet s’est développé une proposition didactique qui a été mise en place dans plusieurs écoles de la Catalogne. Cette approche est basée sur le potentiel éducatif de la chanson improvisée. Dans la dernière partie de l'article nous discutons les possibilités et les limites de l’approche didactique par rapport à la découverte de la poésie par les élèves de l'école primaire. Une des conclusions que nous en tirons est que la chanson improvisée peut devenir un moyen efficace d'aborder la poésie grace au fait qu’elle s’appuie sur un paradigme communicatif de haute signification et très motivant pour les élèves qui y participent. Glosa or improvised song is the name given to a communicative activity that takes place within a community and is channelled through improvised verses sung to tunes with traditional roots. The first part of the paper deals with the arrangement of the lyrics, music and performance of this musical poetic form in order to subsequently present the Corrandescola project. It shows how this project has developed a didactic proposal that has been put into practice in several schools
Entre el ocaso y la ilusión. Hannah Arendt y las posibilidades creadores de la acción humana / Between Decline and Hope. Hannah Arendt and the Creating Possibilities of Human Action
Marcelo Casals
Revista SudHistoria , 2010,
Abstract: The lack of hope in the XX Century, the extremes of exterminating totalitarianism and the inhumanity of mass societies have put in check the concept of human being and his collective creative abilities. Hannah Arendt, intellectual, of Jew-German origins, characterized her own intellectual work for a deep analysis concerning these aspects. In the following article it is pretend to analyze her proposal in base to the “action” concept, understanding this as the human ability to create innovation and impressibility in a collective manner, and insert it in an equality and liberty environment.
Electromagnetic Quantum Field Theory on Kerr-Newman Black Holes
Marc Casals
Physics , 2008,
Abstract: We study classical and quantum aspects of electromagnetic perturbations on black hole space-times. We develop an elegant formalism introduced by Wald, which sets up the theory of linear perturbations in a Type-D background in a compact and transparent manner. We derive expressions for the electromagnetic potential in terms of the single Newman-Penrose scalar \phi_0.This enables the formulation of the quantum theory of the electromagnetic field as that of a complex scalar field. We study the separable field equations obeyed by the various Newman-Penrose scalars in the Kerr-Newman background and find, for various limits, the asymptotic behaviour of the radial and angular solutions. We correct and build on a study by Breuer, Ryan and Waller to find a uniformly valid asymptotic behaviour for large frequency of the angular solutions and the eigenvalues. We follow Candelas, Chrzanowski and Howard (CCH) in their canonical quantization of the electromagnetic potential and field. We perform an asymptotic analysis of the form of the renormalized stress-energy tensor (RSET) in the past Boulware state close to the horizon. Unlike results in CCH, its leading order behaviour close to the horizon corresponds to minus the stress tensor of a thermal distribution at the Hawking temperature rigidly rotating with the horizon. We prove that expressions in CCH for the expectation value of the stress tensor in the past Boulware, past Unruh and |CCH> states lead to a lack of symmetry of the RSET under parity, even though this is a symmetry of the physical system. We derive the correct symmetric expressions and present a detailed analysis of the resulting RSETs.
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