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The Determination of the Velocities after Impact for the Constrained Bar Problem
André Fenili,Luiz Carlos Gadelha de Souza,Bernd Sch fer
Mathematical Problems in Engineering , 2009, DOI: 10.1155/2009/384071
Abstract: A simple mathematical model for a constrained robotic manipulator is investigated. Besides the fact that this model is relatively simple, all the features present in more complex problems are similar to the ones analyzed here. The fully plastic impact is considered in this paper. Expressions for the velocities of the colliding bodies after impact are developed. These expressions are important in the numerical integration of the governing equations of motion when one must exchange the set of unconstrained equations for the set of constrained equation. The theory presented in this work can be applied to problems in which robots have to follow some prescribed patterns or trajectories when in contact with the environment. It can also de applied to problems in which robotic manipulators must handle payloads.
Poly(amidoamine) Hydrogels as Scaffolds for Cell Culturing and Conduits for Peripheral Nerve Regeneration
Fabio Fenili,Amedea Manfredi,Elisabetta Ranucci,Paolo Ferruti
International Journal of Polymer Science , 2011, DOI: 10.1155/2011/161749
Abstract: Biodegradable and biocompatible poly(amidoamine)-(PAA-) based hydrogels have been considered for different tissue engineering applications. First-generation AGMA1 hydrogels, amphoteric but prevailing cationic hydrogels containing carboxylic and guanidine groups as side substituents, show satisfactory results in terms of adhesion and proliferation properties towards different cell lines. Unfortunately, these hydrogels are very swellable materials, breakable on handling, and have been found inadequate for other applications. To overcome this problem, second-generation AGMA1 hydrogels have been prepared adopting a new synthetic method. These new hydrogels exhibit good biological properties in vitro with satisfactory mechanical characteristics. They are obtained in different forms and shapes and successfully tested in vivo for the regeneration of peripheral nerves. This paper reports on our recent efforts in the use of first-and second-generation PAA hydrogels as substrates for cell culturing and tubular scaffold for peripheral nerve regeneration. 1. Introduction Tissue loss or end-stage organ failure caused by injury or other types of damage is one of the most devastating and costly problems in human health care. Surgical strategies that have been developed to address these problems include organ transplantation from one individual to another, tissue transfer from a healthy site to the diseased site in the same individual, and replacement by using mechanical devices such as joint prosthesis or dialysis machine. Moreover, medical treatment encompassed supplementation of metabolic products of the nonfunctional tissue. Though significant advances have been achieved in terms of health care by these therapeutic options, many limitations and unsolved issues remain [1]. The number of organs available for transplantation is far exceeded by the number of patients needing such procedures. In Europe in 2010 alone, approximately 9,300 people were on the waiting list for an organ transplant due to end-stage organ failure, but only 3,100 transplants were performed [2]. Tissue transfer cannot replace all the functions of the original tissue and bears the risk of donor-site complications. Tissue engineering “is an interdisciplinary field that applies the principles of engineering and of life science towards the development of biological substitutes that restore, maintain or improve tissue or organ function.” This definition is based on several articles, by Langer and Vacanti, that were published in the 1990s [3–6]. In those articles tissue engineering is proposed as an
Tania Mara Xavier Scóz,Rosangela Maria Fenili
Revista Eletr?nica de Enfermagem , 2003,
Abstract: The development of projects of attention towards mental health inside the Program of Family Health(PFH) is presented based on a brief rescue of some aspects that compose the PFH, the Psychiatric Reform/MentalHealth and the Unique Heath System. The insertion of attentive actions towards mental health in the PFH from theexistence and the non-existence of one of the substitutives services of the mental health net around the cities,points out some articulation possibilities and an united development of how to do it.
Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology
Daniela Fenili, Ying-Qi Weng, Isabelle Aubert, Mark Nitz, JoAnne McLaurin
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0024032
Abstract: Inositol stereoisomers, myo- and scyllo-inositol, are known to enter the brain and are significantly elevated following oral administration. Elevations in brain inositol levels occur across a concentration gradient as a result of active transport from the periphery. There are two sodium/myo-inositol transporters (SMIT1, SMIT2) that may be responsible for regulating brain inositol levels. The goals of this study were to determine the effects of aging and Alzheimer's disease (AD)-like amyloid pathology on transporter expression, to compare regional expression and to analyze substrate requirements of the inositol transporters. QPCR was used to examine expression of the two transporters in the cortex, hippocampus and cerebellum of TgCRND8 mice, a mouse model of amyloid pathology, in comparison to non-transgenic littermates. In addition, we examined the structural features of inositol required for active transport, utilizing a cell-based competitive uptake assay. Disease pathology did not alter transporter expression in the cortex or hippocampus (p>0.005), with only minimal effects of aging observed in the cerebellum (SMIT1: F2,26 = 12.62; p = 0.0002; SMIT2: F2,26 = 8.71; p = 0.0015). Overall, brain SMIT1 levels were higher than SMIT2, however, regional differences were observed. For SMIT1, at 4 and 6 months cerebellar SMIT1 levels were significantly higher than cortical and hippocampal levels (p<0.05). For SMIT2, at all three ages both cortical and cerebellar SMIT2 levels were significantly higher than hippocampal levels (p<0.05) and at 4 and 6 months of age, cerebellar SMIT2 levels were also significantly higher than cortical levels (p<0.05). Inositol transporter levels are stably expressed as a function of age, and expression is unaltered with disease pathology in the TgCRND8 mouse. Given the fact that scyllo-inositol is currently in clinical trials for the treatment of AD, the stable expression of inositol transporters regardless of disease pathology is an important finding.
A brief comment on the dynamical behavior of a forced nonlinear slewing beam: 1. Superharmonic resonance
Fenili, A.;Souza, L. C. Gadelha de;Balthazar, J. M.;Góes, L. C. S.;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2005, DOI: 10.1590/S1678-58782005000200014
Abstract: this paper describes the dynamical behavior of a nonlinear flexible beam (cubic nonlinearities considered) connected to a dc motor (responsible for the slewing motion) when the angular displacement of the slewing axis and its derivatives are considered to be of a harmonic type and the system is excited near a resonance (present due to the nonlinear contribution).
Application of the center manifold theory to the study of slewing flexible Non-ideal structures with nonlinear curvature: a case study
Fenili, A.;Balthazar, J. M.;Mook, D. T.;Weber, H. I.;
Journal of the Brazilian Society of Mechanical Sciences , 2002, DOI: 10.1590/S0100-73862002000300014
Abstract: in this paper is analyzed the local dynamical behavior of a slewing flexible structure considering nonlinear curvature. the dynamics of the original (nonlinear) governing equations of motion are reduced to the center manifold in the neighborhood of an equilibrium solution with the purpose of locally study the stability of the system. in this critical point, a hopf bifurcation occurs. in this region, one can find values for the control parameter (structural damping coefficient) where the system is unstable and values where the system stability is assured (periodic motion). this local analysis of the system reduced to the center manifold assures the stable / unstable behavior of the original system around a known solution.
Diagnóstico de miastenia gravis en perros
Suraniti,Adriana Patricia; Mundo,Silvia; Bertotti,Alicia Cristina; Terruzzi,P.; Domingo,L.; Fenili,C. A.;
Revista de Medicina Veterinaria , 2010,
Abstract: miastenia gravis is a neuromuscular disease caused by autoantibodies. early clinical and biochemical diagnosis and treatment is demanded in the assurement of quality and time of life in all dogs. in this study we describe the conventional diagnosis methods and therapy in 32 dogs with suspected myasthenia gravis and propose the administration of bromide of piridostigmin as another usefull diagnosis method in dogs.
O fen meno das drogas e as macro-políticas agências e tratados internacionais
Telma Elisa Carraro,Silvia Maria Santos Azevedo dos,Rosangela Maria Fenili,Vera Radünz
Texto & Contexto - Enfermagem , 2004,
Abstract: El artículo trata sobre la cuestión de las macro políticas relacionados al fenómeno de las drogas, procurando la inserción del tema en el escenário internacional. Registra los principales organismos internacionales que se envolucran con el problema, se alando sus historias y sus acciones. Destaca la actuación de la Organización de los Estados Americanos OEA y la formación de la Comisión Interamericana para el Control del Abuso de Drogas CICAD, integrada por los Estados miembros de la OEA.
Rosangela Maria Fenili,Maria Emilia de Oliveira,Odalea M. Brüggemann dos Santos,Elisabeta Roseli Eckert
Revista Eletr?nica de Enfermagem , 2002,
Abstract: This study sought to know and understand how Nursing Graduation Course at Santa CatarinaFederal University evaluates the students. It analyses how the evaluation is structured in teaching programs ofeight subjects of professional period. From data analyses it is possible to observe that the subjects use as a criteriathe marks and all of them attribute different levels to each activity, according to established criteria of the teachers.Thus, it can be said that what is done as learning evaluation is merely a verification. In this sense, the authorspoint out some ways that can redirect this practice.
Orienta o pré-operatória ao cliente - uma medida preventiva aos estressores do processo cirúrgico
Aline Aparecida de Souza,Zelita Chaves de Souza,Rosangela Maria Fenili
Revista Eletr?nica de Enfermagem , 2005,
Abstract: Este trabalho refere-se a uma prática assistencial realizada com clientes, no período pré-operatório, em uma unidade de clínica cirúrgica de um Hospital Universitário. O propósito foi de prevenir e minimizar os estressores do processo cirúrgico de clientes com cirurgias de Vesícula e Hérnia de Parede Abdominal. Para a metodologia nos respaldamos na Teoria de Betty Neumann com contribui o e conceitos de Paulo Freire, trabalhando a educa o em saúde. Foram utilizadas diferentes abordagens, como orienta o pré-operatória, atividades lúdicas e dinamicas. Os resultados desta prática demonstraram que o cliente necessita de um maior esclarecimento e informa o. Os momentos de descontra o, também foram fundamentais no fortalecimento das linhas de defesa do cliente, segundo a teorista. Esta assistência revelou a importancia da aten o prestada pela equipe de enfermagem durante a hospitaliza o.
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