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Search Results: 1 - 10 of 1097 matches for " Feldman GJ "
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Improving the quality of life in patients with chronic obstructive pulmonary disease: focus on indacaterol
Feldman GJ
International Journal of Chronic Obstructive Pulmonary Disease , 2013, DOI: http://dx.doi.org/10.2147/COPD.S31209
Abstract: oving the quality of life in patients with chronic obstructive pulmonary disease: focus on indacaterol Review (1489) Total Article Views Authors: Feldman GJ Published Date February 2013 Volume 2013:8 Pages 89 - 96 DOI: http://dx.doi.org/10.2147/COPD.S31209 Received: 18 September 2012 Accepted: 26 November 2012 Published: 14 February 2013 Gregory J Feldman S Carolina Pharmaceutical Research, Alliance Biomedical Group International, Spartanburg, SC, USA Abstract: Chronic obstructive pulmonary disease (COPD) is a common disease in the general population and it places a considerable burden on patients, with the disease negatively affecting quality of life. In practice, patients with COPD generally seek medical attention because of symptoms, particularly breathlessness, and the resulting physical limitations, which affect the health-related quality of life (HR-QOL) in patients. The defining feature of COPD is airflow limitation that causes air trapping and increased hyperinflation as the ventilation rate increases during physical effort. Hyperinflation causes or worsens breathlessness as breathing becomes inefficient, with the end result being an avoidance of physical exertion and a cycle of increasing dyspnea caused by inactivity and deconditioning, with deleterious effects on HR-QOL. Current published guidelines for COPD state that the goals of pharmacologic therapy should be to control symptoms, improve health status and exercise tolerance, and reduce the frequency of COPD exacerbations. Effective and sustained bronchodilation has emerged as a key strategy for improving dyspnea and ability to exercise. As there is no cure for COPD, a major goal of treatment and of research into new therapies is to improve HR-QOL in COPD patients. Conclusion: More recently, indacaterol, an inhaled ultra-long-acting β2-agonist (24-hour action), has been approved in many countries at different doses (between 75 and 300 μg once daily) for treatment of patients with stable but symptomatic COPD. The aim of this review was to explore once-daily indacaterol clinical data as related to improvement in HR-QOL in COPD. Indacaterol studies have shown significant improvements in lung function of COPD patients, and these improvements have also translated into clinically meaningful improvements in patient symptoms and HR-QOL.
Improving the quality of life in patients with chronic obstructive pulmonary disease: focus on indacaterol
Feldman GJ
International Journal of COPD , 2013,
Abstract: Gregory J FeldmanS Carolina Pharmaceutical Research, Alliance Biomedical Group International, Spartanburg, SC, USAAbstract: Chronic obstructive pulmonary disease (COPD) is a common disease in the general population and it places a considerable burden on patients, with the disease negatively affecting quality of life. In practice, patients with COPD generally seek medical attention because of symptoms, particularly breathlessness, and the resulting physical limitations, which affect the health-related quality of life (HR-QOL) in patients. The defining feature of COPD is airflow limitation that causes air trapping and increased hyperinflation as the ventilation rate increases during physical effort. Hyperinflation causes or worsens breathlessness as breathing becomes inefficient, with the end result being an avoidance of physical exertion and a cycle of increasing dyspnea caused by inactivity and deconditioning, with deleterious effects on HR-QOL. Current published guidelines for COPD state that the goals of pharmacologic therapy should be to control symptoms, improve health status and exercise tolerance, and reduce the frequency of COPD exacerbations. Effective and sustained bronchodilation has emerged as a key strategy for improving dyspnea and ability to exercise. As there is no cure for COPD, a major goal of treatment and of research into new therapies is to improve HR-QOL in COPD patients.Conclusion: More recently, indacaterol, an inhaled ultra-long-acting β2-agonist (24-hour action), has been approved in many countries at different doses (between 75 and 300 μg once daily) for treatment of patients with stable but symptomatic COPD. The aim of this review was to explore once-daily indacaterol clinical data as related to improvement in HR-QOL in COPD. Indacaterol studies have shown significant improvements in lung function of COPD patients, and these improvements have also translated into clinically meaningful improvements in patient symptoms and HR-QOL. Keywords: airflow limitation, bronchodilation, long-acting β2-agonist, COPD
Need for Containment as a Motivation for Facebook Use  [PDF]
Liat Feldman
Social Networking (SN) , 2018, DOI: 10.4236/sn.2018.71001
Abstract:
Research reveals a mixed picture regarding Facebook uses and psychological effects associated with them. This study looks at this issue through the lens of the psychoanalytic concept of containment. We combined this concept with the anxious and avoidant forms of attachment to create a framework with which to investigate the active and passive uses of Facebook. Using a questionnaire administered to 275 Israeli students, we established that the need for containment predicted logging onto and posting on Facebook after negative experiences. In addition, fulfillment of one’s need for containment was associated with posting on Facebook. We also observed a positive change in one’s feelings about oneself and one’s subjective sense of visibility after posting on Facebook. These results offer a new approach to exploring both Facebook use and its effects.
Simplified Approximate Expressions for the Boundary Layer Flow in Cylindrical Sections in Plankton Nets and Trawls  [PDF]
Svein Helge Gj?sund
Open Journal of Marine Science (OJMS) , 2012, DOI: 10.4236/ojms.2012.22009
Abstract: Trawls and plankton nets are basically made up of conical and cylindrical net sections. In conical sections the flow will pass through the inclined net wall with a noticeable angle of attack, and then the flow, filtration and drag can be suitably modelled e.g. by a pressure drop approach [1]. In cylindrical and other non-tapered net sections, such as foreparts and extension pieces in trawls and plankton nets, the flow is directed along the net wall and is best considered in terms of a boundary layer. Boundary layer theory and turbulence models can be used to describe such flow, but this requires extensive numerical modelling and computational effort. Simplified approximate formulas providing a qualitative description of the flow with some quantitative accuracy are therefore also useful. This work presents simplified parametric expressions for boundary layer flow in cylindrical net sections, including the boundary layer thickness and growth rate along the net, the filtration velocity out of the net wall, the decrease in mass flux through the net due to the growing boundary layer, and the effect of twine thickness, flow (towing) velocity and the dimensions of the net. These expressions may be useful for assessing the existence and extension of a boundary layer, for appropriate scaling of boundary layer effects in model tests, for proper placement of velocity measurement probes, for assessing the influence on filtration and clogging of plankton net sections, and more.
Die Q1 gemeenskap as een van die grondtipes van die kerk in die Nuwe Testament
GJ Malan
HTS Theological Studies/Teologiese Studies , 2007,
Abstract: The New Testament bears witness to a wide variety of communities, representing a spectrum of ideas and teachings about Jesus and the meaning of his life. In this article these communities are regarded as prototypes of churches which have a certain bearing on churches and their teachings today. The article aims to investigate communities behind Q as prototypes. It focuses on the community responsible for the first layer of Q material, with the intention of asking whether they might have constituted such a prototype of the church. To achieve this, the “kingdom of God” is studied as their symbolic universe. The result is that, while the Q1 community cannot be called “Christian” or “church” in the strict sense of the word, it challenges the church by representing the kingdom of God in a world of uncertainty, danger, and misuse of power. HTS Theological Studies Vol. 63 (2) 2007: pp. 699-715
Emergency management of injuries sustained during child sexual assault
GJ Pitcher
Continuing Medical Education , 2004,
Abstract:
The Eye of the Earth: Niyi Osundare as a Poet of Nature
GJ Doki
African Research Review , 2009,
Abstract: It can be said with considerable justification that Niyi Osundare is one of the most fecund poets writing in Africa today. A Nigerian of Yoruba extraction, his poetry is richly coloured by common expressions of traditional life (like proverbs and songs) which reflects the world view of his people. Besides, his poetry is accessible because in it he assumes the voice of the unlettered peasants and villagers ‘who speak plain without feigning sophistication’ (Ohaeto 7). His themes are many and varied. They range from a preoccupation with the poor and down-trodden in society to an engagement with Africa’s socio-political problems and a revolutionary vision that will bring about a new Africa. In all these Osundare is not blind to his physical environment. In fact most of Osundare’s poetry dwells on the impoverishment and decay of the rural communities. His fourth collection of poetry The Eye of the Earth is entirely devoted to mother-earth and other forms of physical nature. It is the object of this piece to ascertain the extent to which Osundare qualifies as a poet of nature in this collection.
Does John 17:11b, 21 23 refer to church unity?
GJ Malan
HTS Theological Studies/Teologiese Studies , 2011,
Abstract: In ecumenical circles, John 17:11b, 21–23 has been understood as Jesus’ prayer for church unity, be it confessional or structural. This article questioned such readings and conclusions from historical, literary and sosio-cultural viewpoints. The Fourth Gospel’s language is identified as ’antilanguage’ typical of an ’antisociety’, like that of the Hermetic, Mandean and Qumran sects. Such a society is a separate entity within society at large, but opposes it. Read as a text of an antisociety, John 17:11b, 21–23 legitimises the unity of the separatist Johannine community, which could have comprised several such communities. This community opposed the Judean religion, Gnosticism, the followers of John the Baptist and three major groups in early Christianity. As text from the canon, this Johannine text legitimates tolerance of diversity rather than the confessional or structural unity of the church.
‘On Earth as it is in Heaven...’ The heavenly sanctuary motif in Hebrews 8:5 and its textual connection with the ‘shadowy copy’ [úποδεíγματι καì σκι a] of LXX Exodus 25:40
GJ Steyn
HTS Theological Studies/Teologiese Studies , 2011,
Abstract: This study investigates the explicit quotation from Exodus 25:40 in Hebrews 8:5 where the motif of the earthly sanctuary, understood to be modelled on that of the heavenly sanctuary in some circles of early Judaism and early Christianity, is to be found. Hebrews’ application and interpretation of Exodus 25:40 – in light of the terms úπóδειγμα [example or plan or copy] τúπο [model or design or archetype] by Philo) and σκια [shadow] – is studied within the context of Hebrews 8:1–5. The purpose of this investigation is to explore the possible Graeco-Jewish background(s) of the ‘heavenly sanctuary’ motif in Hebrews 8:5, the presence of its key terminology and some of its intertextual occurrences in, amongst others, the Testament of Levi and Colossians 2:17.
Can the chasms be bridged? Different approaches to Bible reading
GJ Malan
HTS Theological Studies/Teologiese Studies , 2010,
Abstract: Reality confronts theologians with the fact that they themselves and believers across the world read and interpret the Bible in diverse ways. Understanding the reason for this is part of the solution. The essence of the problem is that the quest for meaning is an unending journey with frequent ravines to cross. Invariably, a linguistic, historical, cultural and social chasm opens up between current readers of Biblical texts and the cultural, as well as historically layered, settings in which the documents originated. This review article is a discussion of the ways in which several authors approach the Bible from their different theological vantage points and from different fields of application. It assesses the way in which they understand this problem and how they see a solution. An assessment is made from the historical-literary and social-scientific approach to biblical texts, as practiced in the Netherdutch Reformed Church in Africa. Solutions suggested and applied in this situation are compared to solutions proposed by various authors. There may be a positive outcome: the chasms might be bridged, but only when certain criteria are met and when all parties concerned are willing to work with patience, trust and fearless diligence.
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