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Search Results: 1 - 4 of 4 matches for " Feibelmann "
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Discordancia entre IGF-1 e GH pós-sobrecarga de glicose no rastreamento de acromegalia em paciente com macroprolactinoma: relato de caso e revis?o sobre o tema
Gon?alves, Fabrícia Torres;Feibelmann, Taciana C. Maia;Fernandes, Maria Luiza M. P.;Fonseca, Alessandra R.C.;Arantes, Henrique Pierotti;Jorge, Paulo Tannús;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2007, DOI: 10.1590/S0004-27302007000300020
Abstract: we describe a patient with macroprolactinoma and discrepant insulin-like growth factor (igf-1) concentration (elevated) and growth hormone (gh) values during a 75 g oral glucose tolerance test (normal), that were measured to evaluate the co-secretion of gh by tumor. with the bromocriptin use, the patient achieved normalization of prolactin, but persisted with high levels of igf1, suggesting to be subclinical acromegaly. after the development of new more sensitive gh assays, cases of discrepant gh and igf-1 results have been observed and taken to some authors to suggest that gh nadir concentration during 75 g ogtt used to acromegaly diagnosis and treatment could be lower than values considered currently normal. thus, if this is confirmed, subclinical and oligosymptomatic acromegaly cases could have earlier diagnoses.
Avalia??o da associa??o entre doen?a auto-imune de tireóide e urticária cr?nica idiopática
Feibelmann, Taciana C.M.;Gon?alves, Fabrícia Torres;Daud, Mariana Salom?o;Jorge, André de Sousa;Mantese, S?nia A.O.;Jorge, Paulo Tannús;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2007, DOI: 10.1590/S0004-27302007000700009
Abstract: several studies found a higher prevalence of autoimmune thyroid disease (atd) in patients with chronic urticaria (cu). this relationship may be due to the possible autoimmune etiology in up to one third of the cases of chronic idiopathic urticaria (ciu). however, the frequency of atd ranged from 1.14% to 28.6%. the study began by determining whether there is an association between atd and cu, in a population seen at the same clinic. we compared the frequency of anti-thyroid antibodies and thyroid dysfunction in 49 patients with ciu (group 1) and 112 controls (group 2). in order to support the result found, we studied the prevalence of ciu in 60 patients with atd (group 3) and compared with 29 patients who had non-immune thyroid disease (nitd) (group 4). we did not find a statistical difference for the presence of anti-thyroid antibodies or thyroid dysfunction between groups 1 and 2 (12.24% x 9.82% and 12.24% x 7.14%, respectively). the same occurred for the presence of ciu among groups 3 and 4 (3.33% x 3.44%). in our study it was not possible to demonstrate a relationship between atd and ciu, which means that different populations may present a higher or lower degree of association between these illnesses.
Decision quality instrument for treatment of hip and knee osteoarthritis: a psychometric evaluation
Karen R Sepucha, Dawn Stacey, Catharine F Clay, Yuchiao Chang, Carol Cosenza, Geoffrey Dervin, Janet Dorrwachter, Sandra Feibelmann, Jeffrey N Katz, Stephen A Kearing, Henrik Malchau, Monica Taljaard, Ivan Tomek, Peter Tugwell, Carrie A Levin
BMC Musculoskeletal Disorders , 2011, DOI: 10.1186/1471-2474-12-149
Abstract: The performance of the Hip/Knee Osteoarthritis Decision Quality Instrument (HK-DQI) was evaluated in two samples: (1) a cross-sectional mail survey with 489 patients and 77 providers (study 1); and (2) a randomized controlled trial of a patient decision aid with 138 osteoarthritis patients considering total joint replacement (study 2). The HK-DQI results in two scores. Knowledge items are summed to create a total knowledge score, and a set of goals and concerns are used in a logistic regression model to develop a concordance score. The concordance score measures the proportion of patients whose treatment matched their goals. Hypotheses related to acceptability, feasibility, reliability and validity of the knowledge and concordance scores were examined.In study 1, the HK-DQI was completed by 382 patients (79%) and 45 providers (58%), and in study 2 by 127 patients (92%), with low rates of missing data. The DQI-knowledge score was reproducible (ICC = 0.81) and demonstrated discriminant validity (68% decision aid vs. 54% control, and 78% providers vs. 61% patients) and content validity. The concordance score demonstrated predictive validity, as patients whose treatments were concordant with their goals had more confidence and less regret with their decision compared to those who did not.The HK-DQI is feasible and acceptable to patients. It can be used to assess whether patients with osteoarthritis are making informed decisions about surgery that are concordant with their goals.The decision to undergo total joint replacement (TJR) for treatment of osteoarthritis can be difficult. The indications for surgery are not solely determined based on clinical features such as imaging or extent of disease; rather, providers need to work with their patients to consider how bothered patients are by their symptoms, and discuss their goals and concerns regarding treatment for their joint pain. Clinicians, consumers and researchers have recognized the "patient-centered" nature of thes
Primary pigmented nodular adrenocortical disease associated with Carney complex: case report and literature review
Gon?alves, Fabrícia Torres;Feibelmann, Taciana Carla Maia;Mendes, Cínthia Monteiro;Fernandes, Maria Luiza Mendon?a Pereira;Miranda, Geraldo Henrique Gouvêa de;Gouvêa, Agostinho Pinto;Jorge, Paulo Tannús;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000600007
Abstract: context: carney complex (cnc), a familial multiple neoplasm syndrome with dominant autosomal transmission, is characterized by tumors of the heart, skin, endocrine and peripheral nervous system, and also cutaneous lentiginosis. this is a rare syndrome and its main endocrine manifestation, primary pigmented nodular adrenal disease (ppnad), is an uncommon cause of adrenocorticotropic hormone-independent cushing's syndrome. case report: we report the case of a 20-year-old patient with a history of weight gain, hirsutism, acne, secondary amenorrhea and facial lentiginosis. following the diagnosing of cnc and ppnad, the patient underwent laparoscopic bilateral adrenalectomy, and she evolved with decreasing hypercortisolism. screening was also performed for other tumors related to this syndrome. the diagnostic criteria, screening and follow-up for patients and affected family members are discussed.
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