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Search Results: 1 - 10 of 4040 matches for " Federico Soria "
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Prognostic significance of heart rate in hospitalized patients presenting with myocardial infarction
Lorenzo Fácila,Pedro Morillas,Juan Quiles,Federico Soria
World Journal of Cardiology , 2012, DOI: 10.4330/wjc.v4.i1.15
Abstract: AIM: To investigate the prognostic significance of resting heart rate in patients with acute coronary syndrome (ACS), independent of other known factors. METHODS: Patients 40 years of age or older who had been admitted with acute coronary syndrome (ACS) to one of the 94 hospitals participating in the Prevalence of Peripheral Arterial Disease in Patients with Acute Coronary Syndrome (PAMISCA) study were included. Patients were divided into two groups based on their resting heart rate (HR ≥ or < 70 bpm). Complications were recording during a follow-up period of 1 year. RESULTS: There were 1054 ACS patients analyzed (43.5% with ST segment elevation and 56.5% without elevation). Mean age was 66.6 ± 11.7 years, 70.6% were male and 29.4% of subjects were female. During follow-up, more patients in the HR ≥ 70 bpm group were hospitalized for heart failure and they also had a higher mortality rate. In the multivariate analysis, a heart rate of ≥ 70 bpm was independently related to overall mortality during the follow-up period (hazard ratio 2.5; 95% confidence interval, 1.26-4.97, P = 0.009). CONCLUSION: A resting heart rate ≥ 70 bpm in patients who survive an ACS is an indicator of a high risk of suffering cardiovascular events during follow-up.
Evaluación de los datos del sensor ASTER para estimar la superficie cultivada y los niveles de producción de ca a de azúcar en Tucumán, Argentina An evaluation of ASTER data to estimate sugarcane planted area and production levels in Tucumán, Argentina
Federico J. Soria,Carmina Fandos,Jorge Scandaliaris,Miguel Morandini
Revista Industrial y Agrícola de Tucumán , 2007,
Abstract: En este trabajo se evalúa la capacidad de los datos de las bandas espectrales 2 y 3 del subsistema VNIR (Visible Near Infrared) y la banda espectral 4 del subsistema SWIR (Short Wave Infrared) del sensor ASTER, para estimar la superficie cultivada y los niveles de producción de ca a de azúcar en un área ubicada en el departamento Chicligasta de la provincia de Tucumán, Argentina. Se aplicó la metodología de clasificación multiespectral supervisada. Los resultados obtenidos fueron comparados con los generados con igual metodología utilizando los datos de las bandas 3, 4 y 5 del sensor TM del satélite Landsat 5. El análisis estadístico de la información disponible demostró que los datos del sensor ASTER, en sus bandas 2 y 3 del VNIR, poseen la capacidad de discriminar la superficie y los niveles de producción de ca a de azúcar en el área de estudio. De la comparación estadística de estos resultados con los de la imagen Landsat, resulta que la banda 3 de ASTER y 4 de Landsat poseen una significancia mayor para discriminar niveles de producción, que las bandas 2 y 3 de los respectivos sensores. Ante estos resultados, el sensor ASTER se muestra como una alternativa viable para la discriminación y cuantificación de la ca a de azúcar. In this work, data obtained by Visible Near Infrared (VNIR) bands 2 and 3 and Short Wave Infrared (SWIR) subsystem (band 4) of the ASTER sensor, were evaluated in terms of their potential use in estimating planted surface and production levels of a sugarcane growing area in Chicligasta, province of Tucumán, Argentina. The multiespectral supervised classification methodology was applied. The results were compared with the ones obtained by applying the same methodology to data provided by bands 3, 4 and 5 of Landsat 5 satellite TM sensor. Statistical analysis of the available information demonstrated that data supplied by VNIR bands 2 and 3 of the ASTER sensor allow discriminating sugarcane planted area and production levels in the region under observation. The statistical comparison of these results with the ones obtained with Landsat TM sensor indicated that band 3 of ASTER and band 4 of Landsat have a higher significance than bands 2 and 3 of both sensors for discriminating production levels. Moreover, by comparing them, it was possible to observe that band 3 of ASTER exhibited a better behaviour than band 4 of Landsat. These results show that the ASTER sensor constitutes a feasible alternative to identify and quantify sugarcane production.
Transcriptional Response of Peripheral Blood Mononuclear Cells from Cattle Infected with Mycobacterium bovis
Federico Carlos Blanco, Marcelo Soria, María Verónica Bianco, Fabiana Bigi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0041066
Abstract: Mycobacterium bovis is the causative agent of most cases of bovine tuberculosis. The identification of bTB biomarkers in specific stages of the disease will contribute to a better understanding of the immunopathology associated with tuberculosis and will enable their use in disease diagnosis and prognosis. The aim of this study was to evaluate the gene expression profile induced after specific stimulation of bovine peripheral blood mononuclear cells from cattle infected with M. bovis using the Affymetrix? GeneChip? Bovine Genome Array. A total of 172 genes showed differential expression profile that was statistically significant with log2-fold change >2.5 and <?2.5. Twenty-four out of these genes were upregulated and 148 were downregulated in bovine peripheral blood mononuclear cells of M. bovis-infected cattle. The highest differentially-expressed genes were related to immune and inflammatory responses, apoptosis, endocytosis, cellular trafficking and genes encoding proteins involved in cellular matrix degradation. Microarray results were confirmed in another group of infected cattle by RT-qPCR for the CD14, IL-1R, THBS1, MMP9 and FYVE genes. This study confirms previous findings that have shown that M. bovis infection in cattle results in the downregulation of immune response-related genes. Moreover, it validates the use of microarray platforms in combination with RT-qPCR to identify biomarkers of bovine tuberculosis. In addition, we propose CD14, IL-1R, THBS1, MMP9 and FYVE as potential biomarkers of bovine tuberculosis.
El patrimonio arqueológico frente a las obras de trazado lineal: Caso gasoducto y CTCC Salta Termoandes S.A. (Cobos, Gral. Guemes, Salta)
Soria,Silvia; Vitry,Christian; Santoni,Mirta; Mulvany,Eleonora; Viveros,Federico; Mercado,Antonio; Mamaní,Mabel;
Cuadernos de la Facultad de Humanidades y Ciencias Sociales. Universidad Nacional de Jujuy , 2002,
Abstract: in the process of the construction of the salta termoandes thermoelectrical power station s.a. and its feeding gas pipe, we participate in one of the instances of the environmental impact studies and in an archaeological rescue. as a consequence of this experience, we present the results obtained, which include methodological aspects and the interpretation of the archaeological record localized and rescued. we, as professionals, should cover the necessities of the management of our archaeological heritage. in this direction, we should make an effort to adequate theory, methodology and technology in the solution of practical problems involved in all the stages of the e.i.s. we suggest the formation, in an academic level, of specialists who could develop both basic research and managment of archaeological resources.
Evaluación de los datos del sensor ASTER para estimar la superficie cultivada y los niveles de producción de ca?a de azúcar en Tucumán, Argentina
Soria,Federico J.; Fandos,Carmina; Scandaliaris,Jorge; Morandini,Miguel; Pérez,Daniela R.;
Revista industrial y agr?-cola de Tucum??n , 2007,
Abstract: in this work, data obtained by visible near infrared (vnir) bands 2 and 3 and short wave infrared (swir) subsystem (band 4) of the aster sensor, were evaluated in terms of their potential use in estimating planted surface and production levels of a sugarcane growing area in chicligasta, province of tucumán, argentina. the multiespectral supervised classification methodology was applied. the results were compared with the ones obtained by applying the same methodology to data provided by bands 3, 4 and 5 of landsat 5 satellite tm sensor. statistical analysis of the available information demonstrated that data supplied by vnir bands 2 and 3 of the aster sensor allow discriminating sugarcane planted area and production levels in the region under observation. the statistical comparison of these results with the ones obtained with landsat tm sensor indicated that band 3 of aster and band 4 of landsat have a higher significance than bands 2 and 3 of both sensors for discriminating production levels. moreover, by comparing them, it was possible to observe that band 3 of aster exhibited a better behaviour than band 4 of landsat. these results show that the aster sensor constitutes a feasible alternative to identify and quantify sugarcane production.
Effect of double-balloon enteroscopy on pancreas: An experimental porcine model
Rafael Latorre,Federico Soria,Octavio López-Albors,Ricardo Sarriá
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i37.5181
Abstract: AIM: To evaluate the effect of double-balloon enteroscopy (DBE) on pancreas histology and levels of pancreatic enzymes. METHODS: Conventional upper gastrointestinal endoscopy was performed on five control pigs. Oral DBE was performed with an EN-450T5 enteroscope on 20 pigs. Two experimental groups (10 pigs each) were defined according to DBE duration: 90 min for Group 1 and 140 min for Group 2. During oral insertion, the balloons were not inflated in the descending part of the duodenum to avoid the minor duodenal papilla. Serum amylase, lipase and C-reactive protein (CRP) levels were monitored before the procedure and repeated every 30 min until the exploration was finished, as well as 24 h and 7 d after. After the procedure and for a total of 7 d, the pigs were observed twice a day for signs of decreased activity, irritability, vomiting or anorexia. Gross and microscopic examination of the pancreas was performed on day 7. RESULTS: All animals tolerated DBE without clinical manifestations of acute pancreatitis. Experimental groups had higher levels of enzymes than the control group at 24 h. Throughout the exploration, the amylase levels increased significantly above the baseline 24 h after DBE, although the increase was not statistically significant and did not reach 20% of the baseline. An increase in lipase and CRP was observed at 24 h after the procedure, although by day 7, all enzymatic levels had returned to baseline. No differences between Groups 1 and 2 were found for any enzyme and sampling site during and after the procedure. Similarly, no correlation between insertion depth and enzyme levels was observed. Direct in situ and post-removal inspection of the pancreas did not show any evidence of fluid collection, abscesses or hemorrhage. Histological examination of the pancreas from Groups 1 and 2 revealed the existence of focal areas (0.14-0.26 mm2) of ischemic necrosis in 47.4% of the animals. In the pigs with damaged pancreas, the left lobe (tail) was always affected. However, this only happened in 83.3% of the samples from the right lobe (head) and in 33.3% of the samples from the body of the pancreas. Significant differences were found between the left lobe (tail) and the body for the percentage of affected pancreas. Both the size of the lesions and the percentage of affected pancreas were higher in the left pancreatic lobe (tail). The presence of the lesions was not related to the exploration length. CONCLUSION: The increase in pancreatic enzymes after DBE could be related to focal points of pancreatic ischemic necrosis due to mechanical str
An endoscopic technique for treating symptomatic distal jejunum obstruction by leaving the overtube in place Una técnica endoscópica en el tratamiento de la obstrucción sintomática del yeyuno distal dejando en su lugar el sobretubo
Enrique Pérez-Cuadrado,Fernando Carballo,Rafael Latorre,Federico Soria
Revista Espa?ola de Enfermedades Digestivas , 2013,
Abstract: Double balloon enteroscopy has a limitation for positioning an enteral stent in the distal jejunum through its long, narrow biopsy channel. When the distal end of its overtube is left in place close to the neoplasia with the enteroscope removed, if we push an enteral stent introduction system, it tends to form loops so the technique cannot be performed with this instrument. However, the double balloon colonoscope has a shorter overtube length and using the same push-and-pull technique we can reach the distal jejunum with this instrument by inserting the delivery stent system without loops through its overtube. We present a patient with neoplastic obstruction in the distal jejunum with resolution of his symptoms after positioning an enteral stent.
Increased expression of cystine/glutamate antiporter in multiple sclerosis
Olatz Pampliega, María Domercq, Federico N Soria, Pablo Villoslada, Alfredo Rodríguez-Antigüedad, Carlos Matute
Journal of Neuroinflammation , 2011, DOI: 10.1186/1742-2094-8-63
Abstract: Primary cultures of human monocytes and the cell line U-937 were used to investigate the mechanism of glutamate release. Expression of cystine glutamate exchanger (xCT) was quantified by quantitative PCR, Western blot, flow cytometry and immunohistochemistry in monocytes in vitro, in animals with experimental autoimmune encephalomyelitis (EAE), the animal model of MS, and in samples of MS patients.We show here that human activated monocytes release glutamate through cystine/glutamate antiporter xc- and that the expression of the catalytic subunit xCT is upregulated as a consequence of monocyte activation. In addition, xCT expression is also increased in EAE and in the disease proper. In the later, high expression of xCT occurs both in the central nervous system (CNS) and in peripheral blood cells. In particular, cells from monocyte-macrophage-microglia lineage have higher xCT expression in MS and in EAE, indicating that immune activation upregulates xCT levels, which may result in higher glutamate release and contribution to excitotoxic damage to oligodendrocytes.Together, these results reveal that increased expression of the cystine/glutamate antiporter system xc- in MS provides a link between inflammation and excitotoxicity in demyelinating diseases.Multiple sclerosis (MS) is a chronic, degenerative disease of the CNS, which is characterized by focal lesions with inflammation, demyelination, infiltration of immune cells, oligodendroglial death and axonal degeneration [1-3]. MS is typically considered as a primary inflammatory disease in the early, relapsing phase which progresses to a secondary, progressive stage that is characterized by a diminished inflammatory activity and global brain atrophy [4].Oligodendroglial death and demyelination can occur through glutamate excitotoxicity [5,6], a phenomenon that takes place when an excessive amount of glutamate overactivates ionotropic glutamate receptors (iGluRs). Several observations have linked glutamate excitotoxic
Effect of Copper Coating Nursery Containers on Plant Growth and Root Morphology of Eucalyptus globulus Labill. Cuttings and Seedlings
Fernández,Manuel; Tejero,José Raúl; Pérez,Ignacio; Soria,Francisco; Ruiz,Federico; López,Gustavo;
Silva Lusitana , 2007,
Abstract: plant production in rigid plastic containers is operationally advantageous in nursery eucalyptus production, but root morphology differs from those grown under natural conditions. root systems deformations resulting from nursery culture can affect post-planting growth performance and mechanical stability, being instability of eucalypts a major problem. therefore, in order to improve post-planting response of eucalyptus globulus labill., we tested the effect of chemical root pruning with cuco3xcu(oh)2 on root architecture and plant growth at the nursery and in the field. the concentration of 25 g/l applied to the interior walls of the containers could be suitable for chemical root pruning in cuttings and seedlings. at the end of the nursery growth period, the root morphology of copper-treated plants differed significantly from the untreated ones, but differences in root or shoot dry weights were not significant. in the field, copper-treated plants performed no better than untreated plants four years after planting, and the differences in root morphology observed in the nursery did not affect plant survival or growth. therefore, these results do not recommend the use of chemical root pruning with copper in order to improve stability of e. globulus, at least for the first four years after outplanting.
Next Generation Language Resources using GRID
Federico Calzolari,Eva Sassolini,Manuela Sassi,Sebastiana Cucurullo,Eugenio Picchi,Francesca Bertagna,Alessandro Enea,Monica Monachini,Claudia Soria,Nicoletta Calzolari
Computer Science , 2006,
Abstract: This paper presents a case study concerning the challenges and requirements posed by next generation language resources, realized as an overall model of open, distributed and collaborative language infrastructure. If a sort of "new paradigm" is required, we think that the emerging and still evolving technology connected to Grid computing is a very interesting and suitable one for a concrete realization of this vision. Given the current limitations of Grid computing, it is very important to test the new environment on basic language analysis tools, in order to get the feeling of what are the potentialities and possible limitations connected to its use in NLP. For this reason, we have done some experiments on a module of Linguistic Miner, i.e. the extraction of linguistic patterns from restricted domain corpora.
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