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Search Results: 1 - 10 of 276 matches for " Farideh Zaini "
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Farideh Zaini
Acta Medica Iranica , 1984,
Abstract: The i s c l ation o f Sporot hrix Schencki i in IRAN i s reported from the arm l esions of a housewi f e for the first time. The identity o f the fungus was based on its gross and microscopic cultural morphol ogy including demonstration of its dimorphic character.
Aflatoxin production by Aspergillus flavus isolates from green– tiger shrimps (Penaeus semisulcatus)
Farideh Zaini,S Yousefi,S Dadgar,M Safara
Iranian Journal of Microbiology , 2009,
Abstract: Backgrounds and Objectives: to obtain information about aflatoxigenicity of isolated Aspergillus flavus strains from shrimps."nMaterial and Methods: Forty - three isolates of Aspergillus flavus from cultured green tiger shrimps of Persian Gulf were examined for their ability to produce aflatoxins. Initially two media; Aflatoxin Producing Ability medium and Coconut Agar medium were used to detect fluorescence under UV light, later the presence of aflatoxin in culture extract was confirmed and quantified by high pressure liquid chromatography."nResults: Only 2 (4.6%) isolates fluoresced on Aflatoxin Producing Ability medium and Coconut Agar medium under UV light. In sum, 9 (20.93%) isolates (including the 2 above mentioned isolates) were confirmed to be aflatoxigenic by High Performance Liquid Chromatography. Eight (18.7%) of isolates produced aflatoxin B1 ranging from 0.32 to 12.18 ppb, while 1(2.3%) of isolates produced 18.88 ppb and 0.36 ppb of aflatoxin B1 and aflatoxin B2 respectively. Aspergillus oryzae did not produce any detectable aflatoxins. Although highest level of aflatoxin B1 (18.88 ppb) was detected in an isolate from a hepato-pancreatic sample, no histopathological change was observed in that tissue."nConclusion: Some Aspergillus flavus strains which were isolated from shrimps showed aflatoxin producing ability without any histopathological changes in tissues of contaminated shrimps.
Farideh Zaini,A.S.A Mehbod
Acta Medica Iranica , 1995,
Abstract: Ln this study several tests showed that high level of iron either in sera from patients with rheumatoid arthritis, th alassaemia major or in standard iron solutions, have inhibitory effect Oil capsule production of Cryptococcus neotormans. This work is concerned with the probable role of iron in pigeon's natural resistance against cryptococcal infection: No protease activity was detected in either capsular Of acapsularyeasts whereas high activity of p-glucufonidase was demonstrated in the only experimentally produced acapsular Olle. This suggests the porticipotion of iron in demonstrating pathogenic character oforganism and related aspects.
Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLP
Shirin Farahyar, Farideh Zaini, Parivash Kordbacheh, Sassan Rezaie, Mahin Safara, Reza Raoofian, Mansour Heidari
DARU Journal of Pharmaceutical Sciences , 2013, DOI: 10.1186/2008-2231-21-1
Abstract: The clinical isolates of C. glabrata were collected in an epidemiological survey of candidal infection in immunocompromised patients and consisted of four fluconazole and itraconazole resistant isolates, two fluconazole and itraconazole sensitive isolates, and C. glabrata CBS 138 as reference strain. Antifungal susceptibility patterns of the organisms were determined beforehand by the Clinical and Laboratory Standards Institute (CLSI). The potential gene(s) implicated in antifungal resistance were investigated using complementary DNA- Amplified Fragment Length Polymorphism (cDNA-AFLP). Semi-quantitative RT-PCR was carried out to evaluate the expression of gene(s) in resistant isolates as compared to sensitive and reference strains.The aldo-keto-reductase superfamily (AKR gene) was upregulated in the resistant clinical isolates as assessed by cDNA-AFLP. Semi-quantitative RT-PCR revealed AKR mRNA expression approximately twice that seen in the sensitive isolates. Overexpression of the AKR gene was associated with increased fluconazole and itraconazole resistance in C. glabrata. The data suggest that upregulation of the AKR gene might give a new insight into the mechanism of azole resistance.The incidence of fungal infections has increased over the past two decades. Opportunistic fungal infections occur in immunocompromised hosts [1], particularly among patients infected with human immunodeficiency virus (HIV), individuals receiving immunosuppressive therapy for organ or stem cell transplantation, and cancer patients [2]. Candida glabrata has emerged as a common fungal pathogen in many countries and is often reported as the second most prevalent species after C. albicans[3]. Candida glabrata appears to be innately resistant to fluconazole [4,5] and is less sensitive to it than C. albicans, C. parapsilosis, or C. tropicalis. Studies have shown that mechanisms of azole resistance in C. glabrata are often associated with the upregulation of the genes CgCDR1 (C. glabrata C
Study of the distribution of Malassezia species in patients with pityriasis versicolor and healthy individuals in Tehran, Iran
Bita Tarazooie, Parivash Kordbacheh, Farideh Zaini, Kamiar Zomorodian, Farshid Saadat, Hojjat Zeraati, Zahra Hallaji, Sassan Rezaie
BMC Dermatology , 2004, DOI: 10.1186/1471-5945-4-5
Abstract: Differentiation of all malassezia species performed using morphological features and physiological test including catalase reaction, Tween assimilation test and splitting of esculin.In pityriasis versicolor lesions, the most frequently isolated species was M. globosa (53.3%), followed by M. furfur (25.3%), M. sympodialis(9.3%), M. obtusa (8.1%) and M. slooffiae (4.0%). The most frequently isolated species in the skin of healthy individuals were M. globosa, M. sympodialis, M. furfur, M. sloofiae and M. restricta which respectively made up 41.7%, 25.0%, 23.3%, 6.7% and 3.3% of the isolated species.According to our data, M. globosa was the most prevalent species in the skin of healthy individuals which recovered only in the yeast form. However, the Mycelial form of M. globosa was isolated as the dominant species from pityriasis versicolor lesions. Therefore, the role of predisposing factors in the conversion of this yeast to mycelium and its subsequent involvement in pityriasis versicolor pathogenicity should be considered.Yeasts of the genus Malassezia are known to be members of the skin microflora of human and other warm-blooded vertebrates [1,2]. These lipophilic yeasts are associated with various human diseases, especially pityriasis versicolor (PV), a chronic superficial scaling dermatomycosis [3]. This disease is common in late teens and young adults of both sex and characterized by well-demarcated scaling patches with variable pigmentation [4].Although PV had been described at the beginning of nineteen century [5], until recently classification of its etiologic agent was a matter of debt. This controversy may be caused by various morphological features and fastidious growth requirements of Malassezia yeasts in vitro.The genus of Malassezia has undergone several taxonomic revisions [1,6]. In the last reclassification by Gueho et al, seven distinct species were recognized within this genus, namely M. furfur, M. pachydermatis, M. sympodialis, M. globosa, M. obtusa,
Journal of Applied Sciences in Environmental Sanitation , 2011,
Abstract: This article discusses the present status of municipal solid waste management (MSWM) in Malaysia. The basic situation in large municipalities in Malaysia is one in which available resources are not sufficient to provide adequate municipal services to either the main stream of the population, or to those residing in the slum settlements. Effective waste management is dependent upon achieving informed consensus amongst interested parties. The problem for data collection and planning is the lack of locally available trained personnel and the need for relevant data. Most universities and educational institution fails to offer curriculum in waste management, and this neglect results in a serious lack of trained human resources necessary for the planning and implementation of waste management systems.
Hydronephrosis Index: New Sensitive Reference for Follow up of Fetal Hydronephrosis
Farideh Gharekhanloo
Iranian Journal of Radiology , 2010,
Abstract: Background/Objective: Fetal hydronephrosis (HN)is the most common abnormality that is detected in the prenatal ultrasonography (US) and serial assessment of hydronephrosis by US is often used in clinical decision making. The present study serves to determine quantitative index for follow up of the fetal hydronephrosis versus the routine SFU grading system and AP diameter of pelvis study."nPatients and Methods: This study was performed using GE LOGIQ 500 PRO series system 40. Hydronephrotic kidney in the prenatal US were included and in each fetus hydronephrosis index (HI) was determined and 1, 6, 12 and 18-month follow-up after delivery. We selected a single sagittal view of the kidney. Perimeter of kidney and boundaries of hydronephrotic pericaliceal system within the kidney is outlined and software automatically calculated the area of kidney and dilated pelvis. HI is determined as follows: HI=total area of kidney-area of hydronephrotic sinus/total area x 100 and HI is recorded as dimentionless number."nResult: In 25 cases (62.5%) HI showed decreasing hydronphrosis (higher HI) and in 12 cases (30%) HI showed increasing hydronephrosis (lower HI) and in three cases (1.2%) hydronephrosis was stable. Statistical analysis showed that HI was determined with an objectivity of 97 %. "nConclusion: HI is a sensitive method for the assessment of hydronephrosis overtime, quanitively. Especially, in severe hydronpehrosis that SFU grading system lacks clarity and depends on individual interpretation, the value of HI is greatest in this regard and indicates that HN is improving, deteriorating or stable. Because the extrarenal HN is less harmful, the HI is a better way to follow the HN than AP diameter of renal pelvis. It is a more sensitive indicator of the renal parenchymal status and allows better informed clinical decision making, identifying changes in HN not discerned by the current SFU system.
Transient Osteoporosis of the Hip
Farideh Shahandeh
Iranian Journal of Radiology , 2009,
Abstract: "nTransient osteoporosis of the hip as originally described in women, almost exclusively involved the left hip with the third trimester of pregnancy. It is now recognized as actually being more common in middle-aged men and affecting either hip. "nSymptoms include severe hip pain and decreased range of motion that resolves spontaneously in 6 to 12 months. The etiology is poorly understood, and the disease has been associated with a type of reflex sympathetic dystrophy syndrome. It may be migratory, with subsequent involvement of the opposite hip on an adjacent joint. Radiological changes may simulate indolent infection, osteonecrosis or infiltrative neoplasm. The underlying pathologic condition appears to be bone marrow reaction or edema. Current terminology may refer to this entity as transient bone marrow edema syndrome. Radiographs usually show osteopenia, and bone scan reveals intense activity locally within the femoral head – unlike A.V.N which often displays central photopenia. MRI demonstrates diffuse marrow abnormalities that usually extend from the subchondral femoral head to the inter trochanteric and sub trochanteric regions. There is low signal intensity on T1 weighted MR images and high signal intensity on T2 weighted sequences. The MRI changes reflect the nonspecific marrow reaction or edema that is present. Focal osteoporotic bone marrow defects in the subchondral region or subtle femoral head flattening should be searched for diligently on MR images. Unlike the case with A.V.N. , these defects are usually absent in transient osteoporosis.
Sex bias in copy number variation of olfactory receptor gene family depends on ethnicity
Farideh Shadravan
Frontiers in Genetics , 2013, DOI: 10.3389/fgene.2013.00032
Abstract: Gender plays a pivotal role in the human genetic identity and is also manifested in many genetic disorders particularly mental retardation. In this study its effect on copy number variation (CNV), known to cause genetic disorders was explored. As the olfactory receptor (OR) repertoire comprises the largest human gene family, it was selected for this study, which was carried out within and between three populations, derived from 150 individuals from the 1000 Genome Project. Analysis of 3872 CNVs detected among 791 OR loci, in which 307 loci showed CNV, revealed the following novel findings: Sex bias in CNV was significantly more prevalent in uncommon than common CNV variants of OR pseudogenes, in which the male genome showed more CNVs; and in one-copy number loss compared to complete deletion of OR pseudogenes; both findings implying a more recent evolutionary role for gender. Sex bias in copy number gain was also detected. Another novel finding was that the observed sex bias was largely dependent on ethnicity and was in general absent in East Asians. Using a CNV public database for sick children (International Standard Cytogenomic Array Consortium) the application of these findings for improving clinical molecular diagnostics is discussed by showing an example of sex bias in CNV among kids with autism. Additional clinical relevance is discussed, as the most polymorphic CNV-enriched OR cluster in the human genome, located on chr 15q11.2, is found near the Prader–Willi syndrome/Angelman syndrome bi-directionally imprinted region associated with two well-known mental retardation syndromes. As olfaction represents the primitive cognition in most mammals, arguably in competition with the development of a larger brain, the extensive retention of OR pseudogenes in females of this study, might point to a parent-of-origin indirect regulatory role for OR pseudogenes in the embryonic development of human brain. Thus any perturbation in the temporal regulation of olfactory system could lead to developmental delay disorders including mental retardation.
Developing a Mathematical Model for Hydrate Formation in a Spray Batch Reactor  [PDF]
Mohammad Kazemeini, Farideh Freidoonian, Moslem Fattahi
Advances in Materials Physics and Chemistry (AMPC) , 2012, DOI: 10.4236/ampc.2012.24B062
Abstract: The formation of methane hydrate was undertaken in this research. The purpose of this work was to model the methane hydrate formation with a hydrate-water–methane system in a semi-batch reactor under steady–state, isothermal and isobaric conditions. Obtained results were validated with experiments conducted in a semi-batch spray reactor at low temperatures and high pressures. The investigated formation of gas hydrate from pure methane required physical constants of these materials which were determined through experimental data. The experiments hence, the theoretical calculations were conducted with pure methane and carried out in a spray reactor at 273.95K and 8705kPa to determine the actual amount of hydrate formation in such reactor. Ultimately; the comparison of the results generated from the developed mathematical model with those of experimental data of others indicated a very satisfactory agreement obtained.
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