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Search Results: 1 - 10 of 3279 matches for " Falsey AR "
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Current management of parainfluenza pneumonitis in immunocompromised patients: a review
Falsey AR
Infection and Drug Resistance , 2012, DOI: http://dx.doi.org/10.2147/IDR.S25874
Abstract: rrent management of parainfluenza pneumonitis in immunocompromised patients: a review Review (1590) Total Article Views Authors: Falsey AR Published Date August 2012 Volume 2012:5 Pages 121 - 127 DOI: http://dx.doi.org/10.2147/IDR.S25874 Received: 12 May 2012 Accepted: 28 June 2012 Published: 08 August 2012 Ann R Falsey University of Rochester, Rochester General Hospital, Rochester, NY, USA Abstract: Parainfluenza viruses (PIV) are common respiratory viruses that belong to the Paramyxoviridae family. PIV infection can lead to a wide variety of clinical syndromes ranging from mild upper respiratory illness to severe pneumonia. Severe disease can be seen in elderly or chronically ill persons and may be fatal in persons with compromised immune systems, particularly children with severe combined immunodeficiency disease syndrome and hematopathic stem cell transplant recipients. At present, there are no licensed antiviral agents for the treatment of PIV infection. Aerosolized or systemic ribavirin in combination with intravenous gamma globulin has been reported in small, uncontrolled series and case reports of immunocompromised patients. A number of agents show antiviral activity in vitro and in animals, but none are currently approved for human use.
Current management of parainfluenza pneumonitis in immunocompromised patients: a review
Falsey AR
Infection and Drug Resistance , 2012,
Abstract: Ann R FalseyUniversity of Rochester, Rochester General Hospital, Rochester, NY, USAAbstract: Parainfluenza viruses (PIV) are common respiratory viruses that belong to the Paramyxoviridae family. PIV infection can lead to a wide variety of clinical syndromes ranging from mild upper respiratory illness to severe pneumonia. Severe disease can be seen in elderly or chronically ill persons and may be fatal in persons with compromised immune systems, particularly children with severe combined immunodeficiency disease syndrome and hematopathic stem cell transplant recipients. At present, there are no licensed antiviral agents for the treatment of PIV infection. Aerosolized or systemic ribavirin in combination with intravenous gamma globulin has been reported in small, uncontrolled series and case reports of immunocompromised patients. A number of agents show antiviral activity in vitro and in animals, but none are currently approved for human use.Keywords: parainfluenza virus, antiviral agents, immunocompromised host
Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note
Falsey AR,Becker KL,Swinburn AJ,Nylen ES
International Journal of COPD , 2012,
Abstract: Ann R Falsey1,2, Kenneth L Becker3, Andrew J Swinburne2, Eric S Nylen3, Richard H Snider3, Maria A Formica2, Patricia A Hennessey2, Mary M Criddle2, Derick R Peterson4, Edward E Walsh1,21Department of Medicine, University of Rochester, 2Rochester General Hospital, Rochester, NY, 3Veterans Affairs Medical Center and George Washington University, Washington DC, 4Biostatistics and Computational Biology, University of Rochester, Rochester, NY, USABackground: Serum procalcitonin levels have been used as a biomarker of invasive bacterial infection and recently have been advocated to guide antibiotic therapy in patients with chronic obstructive pulmonary disease (COPD). However, rigorous studies correlating procalcitonin levels with microbiologic data are lacking. Acute exacerbations of COPD (AECOPD) have been linked to viral and bacterial infection as well as noninfectious causes. Therefore, we evaluated procalcitonin as a predictor of viral versus bacterial infection in patients hospitalized with AECOPD with and without evidence of pneumonia.Methods: Adults hospitalized during the winter with symptoms consistent with AECOPD underwent extensive testing for viral, bacterial, and atypical pathogens. Serum procalcitonin levels were measured on day 1 (admission), day 2, and at one month. Clinical and laboratory features of subjects with viral and bacterial diagnoses were compared.Results: In total, 224 subjects with COPD were admitted for 240 respiratory illnesses. Of these, 56 had pneumonia and 184 had AECOPD alone. A microbiologic diagnosis was made in 76 (56%) of 134 illnesses with reliable bacteriology (26 viral infection, 29 bacterial infection, and 21 mixed viral bacterial infection). Mean procalcitonin levels were significantly higher in patients with pneumonia compared with AECOPD. However, discrimination between viral and bacterial infection using a 0.25 ng/mL threshold for bacterial infection in patients with AECOPD was poor.Conclusion: Procalcitonin is useful in COPD patients for alerting clinicians to invasive bacterial infections such as pneumonia but it does not distinguish bacterial from viral and noninfectious causes of AECOPD.Keywords: virus, bacterial infection, procalcitonin, chronic obstructive pulmonary disease, bronchitis
Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note
Falsey AR, Becker KL, Swinburn AJ, Nylen ES, Snider RH, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Walsh EE
International Journal of Chronic Obstructive Pulmonary Disease , 2012, DOI: http://dx.doi.org/10.2147/COPD.S29149
Abstract: ility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note Original Research (3742) Total Article Views Authors: Falsey AR, Becker KL, Swinburn AJ, Nylen ES, Snider RH, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Walsh EE Published Date February 2012 Volume 2012:7 Pages 127 - 135 DOI: http://dx.doi.org/10.2147/COPD.S29149 Received: 15 December 2011 Accepted: 12 January 2012 Published: 23 February 2012 Ann R Falsey1,2, Kenneth L Becker3, Andrew J Swinburne2, Eric S Nylen3, Richard H Snider3, Maria A Formica2, Patricia A Hennessey2, Mary M Criddle2, Derick R Peterson4, Edward E Walsh1,2 1Department of Medicine, University of Rochester, 2Rochester General Hospital, Rochester, NY, 3Veterans Affairs Medical Center and George Washington University, Washington DC, 4Biostatistics and Computational Biology, University of Rochester, Rochester, NY, USA Background: Serum procalcitonin levels have been used as a biomarker of invasive bacterial infection and recently have been advocated to guide antibiotic therapy in patients with chronic obstructive pulmonary disease (COPD). However, rigorous studies correlating procalcitonin levels with microbiologic data are lacking. Acute exacerbations of COPD (AECOPD) have been linked to viral and bacterial infection as well as noninfectious causes. Therefore, we evaluated procalcitonin as a predictor of viral versus bacterial infection in patients hospitalized with AECOPD with and without evidence of pneumonia. Methods: Adults hospitalized during the winter with symptoms consistent with AECOPD underwent extensive testing for viral, bacterial, and atypical pathogens. Serum procalcitonin levels were measured on day 1 (admission), day 2, and at one month. Clinical and laboratory features of subjects with viral and bacterial diagnoses were compared. Results: In total, 224 subjects with COPD were admitted for 240 respiratory illnesses. Of these, 56 had pneumonia and 184 had AECOPD alone. A microbiologic diagnosis was made in 76 (56%) of 134 illnesses with reliable bacteriology (26 viral infection, 29 bacterial infection, and 21 mixed viral bacterial infection). Mean procalcitonin levels were significantly higher in patients with pneumonia compared with AECOPD. However, discrimination between viral and bacterial infection using a 0.25 ng/mL threshold for bacterial infection in patients with AECOPD was poor. Conclusion: Procalcitonin is useful in COPD patients for alerting clinicians to invasive bacterial infections such as pneumonia but it does not distinguish bacterial from viral and noninfectious causes of AECOPD.
Heroes’ Dilemma and Believers’ Dilemma  [PDF]
Ismael Tabu?ar Fortunado
Open Journal of Philosophy (OJPP) , 2016, DOI: 10.4236/ojpp.2016.63024
Abstract: Based on our knowledge, understanding, and wisdom, we choose. We sometimes cannot choose both, two or more and nothing. We either believe what we choose or not because of our intentions. Heroes’ dilemma and Believers’ dilemma are about two choices that both have negative results when chosen, but the person may choose the one better than the other based on his character. The author gave twelve examples, eight examples for heroes’ dilemma and four examples for believers’ dilemma. The choice is the good. Heroes’ dilemma requires an act of heroism and believers’ dilemma requires an act of courage. Actions analyses and textual analyses are observed.
Seizure precipitated during long haul flight
AR Devkota,AR Karki
Journal of Institute of Medicine , 2010, DOI: 10.3126/joim.v32i3.4962
Abstract: We report three diagnosed cases of epilepsy under medication that were on long haul flight from Kathmandu to different destinations in USA with different clinical outcomes during flight. The first case had brief seizure like episode during flight and was given oral benzodiazepine. The second case was put on prophylactic oral benzodiazepine to induce sleep and reduce seizure threshold and had an uneventful flight. The third case developed generalized tonic clonic seizure and was managed accordingly. Key words: Epilepsy; long haul flight; seizure. DOI: http://dx.doi.org/10.3126/joim.v32i3.4962 Journal of Institute of Medicine , December, 2010; 32:3 59-61
Economic Analysis of Biodiesel and Glycerol Carbonate Production Plant by Glycerolysis  [PDF]
Nghi Nguyen, Ya?ar Demirel
Journal of Sustainable Bioenergy Systems (JSBS) , 2013, DOI: 10.4236/jsbs.2013.33029
Abstract: Techno-economic analysis of an indirect use of carbon dioxide within the route of glycerolysis of glycerol with urea is investigated. The results show that the net present value of the biodiesel-glycerol carbonate production by glycerolysis is higher than the biodiesel-glycerol carbonate production by direct carboxylationat at the end of the 12-year operation with similar capacities. The stochastic model has predicted that using glycerolysis route for the synthesis of glycerol carbonate production might increase the probability of getting positive net present value by about 15%.
Crisis and Social Security in Spain  [PDF]
Arántzazu Vicente-Palacio
Beijing Law Review (BLR) , 2015, DOI: 10.4236/blr.2015.64024
Abstract: This paper outlines the latest reforms introduced into the Social Security System’s protective actions in order to deduce whether such intense changes allow us to conclude that a Social Security crisis exists. This concept is understood from the perspective of the Social Security being capable, or not, of undertaking its historical mission. This work takes into account the legislative reforms made to Social Security, along with the changes that are taking place, in the form of providing services in the new post-capitalist society.
Changes in Productive Organisation, Outsourcing and Multiservice Companies (A New Workers’ Category: “Sub-Ceded” Worker)  [PDF]
Arántzazu Vicente-Palacio
Beijing Law Review (BLR) , 2018, DOI: 10.4236/blr.2018.92017
Abstract: The outsourcing phenomenon has increased considerably in recent years, and the appearance and rapid spread of multiservice or all-round management companies have, in turn, substantially contributed to this phenomenon. All this has been made possible by numerous economic and legal causes, with the Employment Law still having to react to the precariousness of the legal statute of this new worker category: the “subceded” worker by finishing with some proposals for which the lawmaker takes his/her responsibility and puts an end to today’s harmful legal anomie.
La possibilité d'éviter des ovipositions irrégulières grace au nanisme lié au sexe
AR Kuit
Genetics Selection Evolution , 1971, DOI: 10.1186/1297-9686-3-3-383a
Abstract:
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