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Mixed variant calcinosis cutis
Fakeha Firdous,Idrees Akhter Afroz,Syed Sibghatullah Quadri,Atiya Begum
Journal of Medical and Allied Sciences , 2012,
Abstract: A 7 year old boy presented with multiple, raised, hard nodules of varying sizes over both elbows and right knee and small milia like lesions over the chin. Serum levels of calcium, phosphorus and uric acid were normal. Fine needle aspiration cytology (FNAC) followed by excisional biopsy was done. A final diagnosis of calcinosis cutis was made based on histopathological and clinical findings. This is a rare case of mixed variants/subtypes-subepidermal calcified nodules and milia like lesions.
GLAUCOMA CAPSULARE
MUHAMMAD FIRDOUS
The Professional Medical Journal , 2009,
Abstract: Purpose of Study: To emphasize the role of filtration surgery in the treatment of glaucoma capsulare. Moreover the study also highlights the importance of thorough ocular examination and diagnosis as the condition is likely to be missed. Material, Methods and Results: This study was conducted to find out the results of filtration surgery (trabeculectomy) in such cases. Forty cases with pseudoexfoliation glaucoma presenting in the Dept of Ophthalmology PAF Hospital Mushaf Sargodha were included. These patients were initially treated with topical medications for three months. Thirty cases that showed poor response to drugs were operated upon and a trabeculectomy was performed. Postoperative pressure readings were recorded twice weekly for the first two months and then once monthly for four months. After a follow-up of six months, twenty five cases (83.33%) were effectively controlled without any added medications whereas five cases (16.67%) required addition of a single drug to achieve the desired effect. Conclusion: The response to medical treatment is generally not satisfactory and surgery has to be undertaken as a final resort. Trabeculectomy is the safe and effective operation in glaucoma capsulare (pseudoexfoliation glaucoma).
CUCI TANGAN SEBELUM MAKAN MENURUNKAN RISIKO KEJADIAN HEPATITIS AKUT KLINIS
Umar Firdous
Bulletin of Health Research , 2012,
Abstract: In the area of Hepatitis A outbreak, washing hand before handling food is very important, because most of the cases do not wash their hand before breakfast, lunch or dinner and they eat without spoon. This study is to find out relation between washing hand before handling food with clinical acute hepatitis cases in the area of Hepatitis A outbreak. This study used a case control design, analysing secondary data of Hepatitis A outbreak investigation from November 2001 to January 2002. The population is a the community which living in Calincing housing in Cogreg Village, Parungsub district of Bogor, aged between 15 to 55 years old. Sixty cases and 120 controls have been analysed. Result of this study found that there is a significant relation (p=0.000) between washing hand before handling food with clinical acute hepatitis case, OR=3.442 (95% CI: 1.638- 7.235). Education is a confounding variable to this relation.
Thermophysical properties of dunite rocks as a function of temperature along with the prediction of effective thermal conductivity  [PDF]
Aurang Zeb, Tayyaba Firdous, Asghari Maqsood
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.26077
Abstract: The thermal conductivity, thermal diffusivity and heat capacity per unit volume of dunite rocks taken from Chillas near Gilgit, Pakistan have been measured simultaneously using transient plane source technique. The temperature dependence of thermal transport properties is studied in the temperature range 83-303 K. Different relations for the estimation of thermal conductivity are also tested. Thermal conductivity data obey the modified Eucken’s law in the temperature range of measurements.
Performance Evaluation of Efficient XOR Structures in Quantum-Dot Cellular Automata (QCA)  [PDF]
Mohammad Rafiq Beigh, Mohammad Mustafa, Firdous Ahmad
Circuits and Systems (CS) , 2013, DOI: 10.4236/cs.2013.42020
Abstract:

Quantum-dot cellular automaton (QCA) is an emerging, promising, future generation nanoelectronic computational architecture that encodes binary information as electronic charge configuration of a cell. It is a digital logic architecture that uses single electrons in arrays of quantum dots to perform binary operations. Fundamental unit in building of QCA circuits is a QCA cell. A QCA cell is an elementary building block which can be used to build basic gates and logic devices in QCA architectures. This paper evaluates the performance of various implementations of QCA based XOR gates and proposes various novel layouts with better performance parameters. We presented the various QCA circuit design methodology for XOR gate. These layouts show less number of crossovers and lesser cell count as compared to the conventional layouts already present in the literature. These design topologies have special functions in communication based circuit applications. They are particularly useful in phase detectors in digital circuits, arithmetic operations and error detection & correction circuits. The comparison of various circuit designs is also given. The proposed designs can be effectively used to realize more complex circuits. The simulations in the present work have been carried out using QCADesigner tool.

Immunohistochemical expression and correlation of mammaglobin with the grading system of breast carcinoma
Rehman Fakeha,Nagi A,Hussain Mahwish
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Objectives: In this study it was intended to study mammaglobin expression as a marker for the detection of breast cancer and correlate it with the Bloom-Richardson grading system of breast carcinoma. Materials and Methods: The study was conducted from May 2007 to May 2008. Tissue samples were collected from 50 patients of breast cancer in the various stages of their disease and correlated histologically with the Bloom-Richardson grading system for breast carcinoma. The clinical data of the patients were obtained from their respective files. Results: Positive immunostaining for mammaglobin was seen in 84% of breast carcinoma cases. This immunoreactivity did not correlate with histological and nuclear grades of the tumors, yet it varied according to the histological type of the tumor with ductal carcinoma showing stronger and diffuse staining than other varieties. Conclusion: These results elicit that mammaglobin is overexpressed in carcinoma breast as compared to the normal breast epithelium. This mammaglobin expression can act as a useful tool in the diagnosis of women with breast cancer.
Acute management of vascular air embolism
Shaikh Nissar,Ummunisa Firdous
Journal of Emergencies, Trauma and Shock , 2009,
Abstract: Vascular air embolism (VAE) is known since early nineteenth century. It is the entrainment of air or gas from operative field or other communications into the venous or arterial vasculature. Exact incidence of VAE is difficult to estimate. High risk surgeries for VAE are sitting position and posterior fossa neurosurgeries, cesarean section, laparoscopic, orthopedic, surgeries invasive procedures, pulmonary overpressure syndrome, and decompression syndrome. Risk factors for VAE are operative site 5 cm above the heart, creation of pressure gradient which will facilitate entry of air into the circulation, orogenital sex during pregnancy, rapid ascent in scuba (self contained underwater breathing apparatus) divers and barotrauma or chest trauma. Large bolus of air can lead to right ventricular air lock and immediate fatality. In up to 35% patient, the foramen ovale is patent which can cause paradoxical arterial air embolism. VAE affects cardiovascular, pulmonary and central nervous system. High index of clinical suspicion is must to diagnose VAE. The transesophgeal echocardiography is the most sensitive device which will detect smallest amount of air in the circulation. Treatment of VAE is to prevent further entrainment of air, reduce the volume of air entrained and haemodynamic support. Mortality of VAE ranges from 48 to 80%. VAE can be prevented significantly by proper positioning during surgery, optimal hydration, avoiding use of nitrous oxide, meticulous care during insertion, removal of central venous catheter, proper guidance, and training of scuba divers.
Peripartum pulmonary embolism: Anesthetic and surgical considerations  [PDF]
Nissar Shaikh, Firdous Ummunnisa, Naseera Aboobacker, Mustafa Gazali, Ousama Kokash
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.31A030
Abstract:

Pregnancy and peripartum period leads to Virchow’s triad (hypercoagulability, venous stasis and vascular injury) thereby increasing the risk of thromboembolism by many folds in these patients. Accurate diagnosis of peripartum pulmonary embolism is pertinent for reducing morbidity and mortality. Accurate diagnosis is also vital for avoiding the adverse effects of unwanted anticoagulation in pregnant mother and fetus in a patient wrongly diagnosed with this condition. Computerized tomographic pulmonary angiography has a high specificity and sensitivity in comparison to ventilation/perfusion scan for diagnosis of peripartum pulmonary embolism (PPE). It has a lower fetal radiation exposure and aids in arriving at an alternative diagnosis, if PPE is absent. Low molecular weight heparin is the medication of choice in the treatment of peripartum pulmonary embolism. Thrombolysis is considered in patients with massive PPE and hemodynamic instability, refractory hypoxia or right ventricular dysfunction. Regional anesthesia/analgesia can be given safely in these patients. We report two cases of PPE and review the anesthetic and surgical consideration.

Novel Adder Circuits Based On Quantum-Dot Cellular Automata (QCA)  [PDF]
Firdous Ahmad, Ghulam Mohiuddin Bhat, Peer Zahoor Ahmad
Circuits and Systems (CS) , 2014, DOI: 10.4236/cs.2014.56016
Abstract:

Quantum-dot cellular automaton (QCA) is a novel nanotechnology that provides a very different computation platform than traditional CMOS, in which polarization of electrons indicates the digital information. This paper demonstrates designing combinational circuits based on quantum-dot cellular automata (QCA) nanotechnology, which offers a way to implement logic and all interconnections with only one homogeneous layer of cells. In this paper, the authors have proposed a novel design of XOR gate. This model proves designing capabilities of combinational circuits that are compatible with QCA gates within nano-scale. Novel adder circuits such as half adders, full adders, which avoid the fore, mentioned noise paths, crossovers by careful clocking organization, have been proposed. Experiment results show that the performance of proposed designs is more efficient than conventional designs. The modular layouts are verified with the freely available QCA Designer tool.

HEAD AND NECK RECONSTRUCTION
FIRDOUS KHAN,SYED ASIF SHAH
The Professional Medical Journal , 2011,
Abstract: The pectoralis major myocutaneous pedicle flap (PMMPF) has been considered to be the "workhorse" ofpedicled flaps in head and neck reconstruction. Despite the use of free flaps, this flap is still considered the mainstay of head and neckreconstruction. The flap is usually associated with a high incidence of complications compared with the free fasciocutaneous flaps yet its size,viability, and versatility make it a valuable tool for extending the limits of resectability and reconstruction. It is type V muscle flap with thedominant vascular supply from the pectoral branch of thoracoacromial artery. Objective: To share our experience of pectoralis majormyocutaneous pedicle flap in selected cases of head and neck reconstruction. The indications, type of reconstruction and complications of theflap utilization were evaluated. Patients and Methods: Between March 2005 and August 2010, a 37 head and neck reconstructive proceduresusing the PMMPF were carried out. The indications for the flap use were defects due to resection of stage II-IV cancer in the head and neckregion. The site, stage of the disease and the postoperative complications were all documented. Results: Pectoralis major myocutaneouspedicled flap reconstructions were used to reconstruct defects in the following sites: oral cavity (25 patients); oropharynx/ hypopharynx, (7patients); and neck or face (5 patients). Of the 37 PMMPF reconstructions, 30 flaps were carried out as primary reconstructive procedures,whereas 7 flaps were "salvage" procedures. Twentyfive patients (67.59%) had complications. A higher complication rates were associated withthe utilization of the flap as a salvage procedure, number of co- morbidities, and in oral cavity reconstructions. Conclusions: The pectoralismajor myocutaneous pedicled flap is still an acceptable method of head and neck reconstruction. It is fast, reliable, provides safe repair and isindicated especially where bulk is needed.
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