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Search Results: 1 - 10 of 73500 matches for " Fa-Xing Yu "
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Tandem ChoRE and CCAAT Motifs and Associated Factors Regulate Txnip Expression in Response to Glucose or Adenosine-Containing Molecules
Fa-Xing Yu,Yan Luo
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0008397
Abstract: Thioredoxin interacting protein (Txnip) is a multifunctional protein involved in regulation of cell cycle events and cellular metabolism. The expression of Txnip is known to be induced by glucose, adenosine-containing molecules, and other physiological cues; however, the underlying regulatory mechanisms remain elusive.
CBP/p300 and SIRT1 Are Involved in Transcriptional Regulation of S-Phase Specific Histone Genes
Hongpeng He, Fa-Xing Yu, Chi Sun, Yan Luo
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0022088
Abstract: Background Histones constitute a type of essential nuclear proteins important for chromatin structure and functions. The expression of major histones is strictly confined to the S phase of a cell cycle and tightly coupled to DNA replication. Methodology/Principal Findings With RT-qPCR and ChIP assays, we investigated transcriptional regulation of the S-phase specific histone genes and found that the acetylation level of histones on core histone gene promoters fluctuated during cell cycle in a pattern similar to RNA polymerase II association. Further, we showed that CBP/p300 and SIRT1 were recruited to histone gene promoters in an NPAT-dependent manner, knockdown of which affected histone acetylation on histone gene promoters and histone gene transcription. Significance These observations contribute to further understanding of the mechanism by which the expression of canonical histone genes is regulated, and also implicate a link between histone expression and DNA damage repair and cell metabolism.
Research on the Algorithms for Registration in Sensor Network for Target Tracking
Ling Wu,Fa-Xing Lu
International Journal of Distributed Sensor Networks , 2009, DOI: 10.1080/15501320802533608
Abstract: To gain benefit from netted sensors, it is essential to correctly integrate each sensor into a global frame of reference. The process is termed sensor registration. It involves minimizing the effects of the errors from the imprecisely known relative positions or orientations of the various sensors, the biased sensor measurements, the offset sensor clocks, and so on. In the paper, a model of a typical sensor registration problem in a 2-sensor scenario is presented for illustration. Four kinds of registration errors, i.e., calibration errors (offsets), attitude (orientation) errors, position errors, and timing errors are mainly discussed in literatures, and literatures are categorized in the paper by its purpose that which one of the four kinds of errors, or which combination of the decoupled errors among them is aimed to solve. The registration errors can be viewed as constant and they can also vary or drift slowly. To address them, different kinds of algorithms have been developed. The algorithms for sensor registration can be divided into three types referred to as Type 1, Type 2, and Type 3 respectively. Algorithms of Type 1, mainly including batch processing methods and meta-heuristic optimization ones, are applied to cases that the registration errors are constant over time. Algorithms of Type 2 provide online estimation of sensor biases, but it is decoupled from the target estimation. The assumption for constant errors is relaxed, and the approaches are extended to cope with both constant and varying errors. The algorithms of Type 3 attempt to simultaneously solve for target variables and sensor systematic biases, and most of them achieve this via augmented state Kalman filter with the augmented state vector combining the target states and sensor uncertainty. References are accordingly organized by type, discussed, and annotated. Related issues of sensor registration are concerned including the non-unique detection probability, the asynchronous sensor measurements, the observability of registration problem, the relative registration and absolute registration, and the performance bounds of the estimator of the registration errors. The developed techniques for solving the problems are summarized respectively. The paper is concluded with a brief summary and some thoughts on the future trends and research directions.
Global Existence of Postive Periodic Solution of a Neutral Type Predator-prey System with Holling Type II Functional Response

CHEN Feng-De,CHEN Xiao-Xing,LIN Fa-Xing,HUANG Chun-Chao,

数学物理学报(A辑) , 2005,
Abstract: The authors first establish the neutral type predator-prey system with Holling type II functional response, then by developing some new technique of analysis and using a continuation theorem based on coincidence degree theory, the authors study the global existence of positive periodic solution for the above model. A set of easily verifiable sufficient conditions is obtained. Example shows that our main results are feasible.
Organic Acid Composition in the Pulp of Loquat (Eriobotrya japonica Lindl.) and Distribution in Fruits

CHEN Fa-xing,LIU Xing-hui,CHEN Li-song,

热带亚热带植物学报 , 2008,
Abstract: Organic acids from the ripe pulp of 18 loquat (Eriobotrya japonica Lindl.) cultivars ('Xiaomaopipa','Jiajiao', 'Zhuonan 1', 'Jiefangzhong', 'Fuyang', 'Moriowase', 'Huabao 2', 'Xiangzhong 10', 'Baihua','Toi', 'Duobao 2', 'Wugongbai', 'Luoyangchin', 'Mogi', 'Zaozhong 6', 'Ba ili', 'Tantou 4', 'Changhong3') and their distribution in the ripe fruit of 2 cultivars ('Jiefangzhong' and 'Zaozhong 6' ) were determined byhigh-performance ion-exchange chromatography (HPIC). Eight organic acids (malic, quinic, citric, iso-citric, α-ketoglutaric, fumaric, oxaloacetic and tartaric acids) were identified in ripe pulp, while trace quantities of ferulic,cis-aconitic and β-coumaric acids were identified in several cultivars. The predominant organic acid of ripe pulp ofmost cultivars was malic acid, with an average content of 4 399 mg kg-1 FW for all cultivars, accounting for62.7% of the total acids. Quinic acid was the second in abundance, with an average content of 2 042 mg kg-1 FW,accounting for 29.1% of the total acids. Other acids ranged from trace to 3.0% of the total acids. Considerablevariations in titratable acidity and organic acid content exist among cultivars. Based on titratable acidity, 18 culti-vars could be separated into 5 groups by clustering analysis: very high acidity ('Xiaomaopipa'), high acidity('Jiajiao', 'Zhuonan 1 ', 'Jiefangzhong' and 'Fuyang' ), medium acidity ('Moriowase', 'Huabao 2', 'Xiang-zhong 10', 'Baihua', 'Toi', 'Duobao 2 '), low acidity ('Wugongbai', 'Luoyangchin ', 'Mogi' and 'Zaozhong 6' ), and very low acidity ('Baili', 'Tantou 4' and 'Changhong 3' ). No significant difference wasfound in the absolute amounts of total acids and titratable acidity between pulp and skins, while the amounts of to-tal acids and titratable acidity in seeds was far lower than those in pulp and skins. The major organic acids identi-fied in skins and seeds were malic and quinic acids. In skins, the content of malic acid was far higher than quinicacid, but in seeds it was slightly lower than quinic acid. In addition, malic acid and quinic acid content in seedswas far lower than those in pulp and skins.
Continuous Regional Arterial Infusion with Fluorouracil and Octreotide Attenuates Severe Acute Pancreatitis in a Canine Model
Meng Tao Zhou, Bi Cheng Chen, Hong Wei Sun, Yue Peng Jin, Fa Jing Yang, Xing Zhang, Roland Andersson, Qi Yu Zhang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0037347
Abstract: Aim To investigate the therapeutic effects of fluorouracil (5-Fu) and octreotide (Oct) continuous regional arterial infusion (CRAI,) alone or in combination, was administered in a canine model of severe acute pancreatitis (SAP). Materials and Methods The animals were divided into five groups; group A (Sham), group B (SAP), group C (SAP and 5-Fu), group D (SAP and Oct), and group E (SAP and 5-Fu + Oct). Levels of amylase, α-tumor necrosis factor (TNF-α), blood urea nitrogen (BUN), creatinine, thromboxane B2 and 6-keto- prostaglandin F1α were measured both before and after the induction of SAP. Pathologic examination of the pancreas and kidneys was performed after termination of the study. Results Pathologic changes noted in the pancreas in SAP significantly improved following CRAI with either single or combined administration of 5-Fu and Oct, where combination therapy demonstrated the lowest injury score. All treatment groups had significantly lower levels of serum TNF-α and amylase activity (P<0.05), though only groups D and E had a lower BUN level as compared to group B. The plasma thromboxane B2 level increased in SAP, but the ratio of thromboxane B2/6-keto- prostaglandin F1α decreased in the treatment groups, with the combination therapy (group E) demonstrating the lowest ratio as compared to the other 3 experimental groups (P<0.05). Conclusions The findings in the present study demonstrate an attenuation of SAP in a canine model following CRAI administration with 5-Fu or Oct, alone or in combination.
Estimation of Water Vapor Amount over Beijing from Sun Photometer Measurements

ZHANG Yu-xiang,LI Xiao-jing,GU Xing-fa,

遥感学报 , 2006,
Abstract: 基于CE318自动跟踪太阳光度计水汽通道(936nm)和一个窗区通道(870nm)的北京上空太阳直射辐射观测数据,利用修改的兰勒方法对大气柱水汽含量的估算方法,开展了太阳光度计的标定和北京上空水汽含量的计算等。利用探空观测结果对太阳光度计测量水汽量的标定显示,二者的线性相关性为0.986,定标不确定度为0.024g/cm^2。利用该方法对从2002至2004年观测的北京地区水汽含量进行了估算,结果表明在1,2,3,11,12月份,北京地区大气柱的水汽含量基本上小于0.5g/cm^2,三年中同月份水汽含量的平均值有较好的一致性。
A Regional Algorithm to Estimate Sea Surface Temperature in the East China Sea

ZHU Li,GU Xing-fa,WANG Qiao,YU Tao,LI Li,

遥感技术与应用 , 2008,
Abstract: This paper proposes a regional algorithm to estimate sea surface temperature (SST) in the East China Sea has been developed using MODIS data aboard Terra and the coefficients of the algorithm were ascertained using MODTRAN 4.0 code and TIGR profiles.The East China Sea's 24 profiles were chosen from TIGR database to input the MOTRAN4 code to calculate the at sensor apparent brightness temperatures in MODIS band 20,29,31 and 32 under 21 observation angles (from 0 to 65 degree) and the coefficients were obtained from the 3,528 samples using the least square method.The preliminary results show a good agreement between SSTs estimated by the proposed algorithm for Terra MODIS data and MODIS SST products.The comparison of the SSTs estimated by the proposed algorithm with concurrent in situ data showed an accuracy of about 1K.With observation angles increase the accuracy deduced from 0.68K to 1.16K.The accuracy of the proposed algorithm was better than that used in MOD28.Our future work would be conducted to collect more profiles and in situ data and improve the accuracy of our algorithm in large observation angles.

XIE Xing-hua,SU Bao-yu,GAO Yan-fa,Duan Xiang-bao,

岩石力学与工程学报 , 2005,
Abstract: 矿井承压水上采煤底板突水问题是一个困难的问题。困难之处就在于影响因素太多,而且由于矿井条件的不同,难以找到统一的处理模式。从水力劈裂的机理入手,通过分析工作面推进过程中采场及采空区底板力学条件变化导致的渗透性改变,来推断底板突水的危险程度。在分析过程中,引入了损伤的概念。损伤被用来描述采场底板的破坏程度(结构演变情况),底板岩体的破坏直接导致底板渗透性的改变;渗透性的改变为承压水提供了通路,增加了底板突水的可能性。针对正交各向异性岩体建立了渗透系数与损伤变量的函数关系,以此描述底板破坏对渗透性的影响。针对具体的算例,得到了矿井底板突水的危险位置。
Study on Plant Species Diversity and Vegetation of Ung Kong Islands

MENG Yu-Fang,WANG Fa-Guo,XING Fu-Wu,FU Lin,

植物科学学报 , 2011,
Abstract: Based on investigation and reference consultation,plant species diversity and vegetation of Ung Kong Islands in Hong Kong were studied,including flora composition,characteristics,distribution type,and its relationship with neighboring regions.Results showed that there were 166 vascular plants belonging to 138 genera and 69 families,including 10 species in 8 genera and 7 families of ferns,2 species in 2 genera and 2 families of gymnosperms,and 154 species in 128 genera and 60 families of angiosperms in the U...
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