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Search Results: 1 - 10 of 495855 matches for " F. M.; Rocha "
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Snai-1 and Epithelial-Mesenchymal Transition-Related Protein Immunoexpression in Canine Mammary Carcinomas  [PDF]
Breno S. Salgado, Rafael M. Rocha, Fernando A. Soares, Fátima G?rtner, Noeme S. Rocha
Advances in Breast Cancer Research (ABCR) , 2014, DOI: 10.4236/abcr.2014.34017
Abstract: Epithelial-mesenchymal transition (EMT) is defined as switching of polarized epithelial cells to a migratory fibroblastoid phenotype. EMT is known to be involved in the progression and metastasis of various cancers in humans, but this specific process is still little explored in the veterinary literature. The aim of this research was to evaluate the expression of EMT-related proteins in canine mammary carcinomas (CMCs). The expression of six EMT-related proteins in 94 CMCs of female dogs was evaluated by immunohistochemistry using a tissue array method. Additionally, clinicopathological characteristics were compared with the expression of EMT-related proteins. Loss of epithelial protein and/or acquisition of the expression of mesenchymal proteins were observed in CMCs. Loss of epithelial protein and/or acquisition of the expression of mesenchymal proteins were observed, particularly in tumors with evidence of stromal invasion; however, significance was only observed between the S100A4 and vascular invasion. In addition, Snai-1 nuclear immunoexpression was significantly related to E-cadherin loss. In conclusion, loss of epithelial proteins and/or the acquisition of mesenchymal proteins are associated with EMT and may have an important role in the evaluation of CMC patients. The unique immunoexpression pattern of Snai-1 could help to distinguish between an adenoma and a non-metastatic carcinoma and seems to be related to conversion of myoepithelial cells to a complete mesenchymal-like phenotype. Loss of E-cadherin and cytokeratin and change of immunoexpression pattern of Snai-1, N-cadherin, S100A4 and MMP-2 indicate the occurrence of EMT in canine mammary carcinomas and should result in an en bloc resection or a close follow-up.
Charged Gravastar in a Dark Energy Universe  [PDF]
C. F. C. Brandt, R. Chan, M. F. A. da Silva, P. Rocha
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.46118

Here we constructed a charged gravastar model formed by an interior de Sitter spacetime, a charged dynamical infinitely thin shell with an equation of state and an exterior de Sitter-Reissner-Nordstrom spacetime. We find that the presence of the charge is crucial to the stability of these structures. It can as much favor the stability of a bounded excursion gravastar, and still converting it in a stable gravastar, as make disappear a stable gravastar, depending on the range of the charge considered. There is also formation of black holes and, above certain values, the presence of the charge allows the formation of naked singularity. This is an important example in which a naked singularity emerges as a consequence of unstabilities of a gravastar model, which reinforces that gravastar is not an alternative model to black hole.

Feeding habits and microhabitat utilization by two syntopic Brazilian Amazonian frogs (Hyla minuta and Pseudopaludicula sp. (gr. falcipes)
Revista Brasileira de Biologia , 1998, DOI: 10.1590/S0034-71081998000400003
Abstract: we studied the feeding habits and microhabitat use of the amazonian frogs hyla minuta and pseudopaludicula sp. at serra norte, carajás, brazil. although living syntopically, the two species differed markedly in both prey types and sizes. standardized feeding niche breadth of h. minuta (bst = 0.572) was larger than that of pseudopaludicula sp. (bst = 0.149) and their feeding niche overlap was considerably low (10.5%). the two frog species also differed in microhabitat use. when active, pseudopaludicula sp. were found partially submerged at the lake border whereas h. minuta were found predominantly on nymphaea sp. leaves. although we have not evaluated taxonomic effects on diet composition, differences in diet may be partially explained by differences in microhabitat use and frogs' size.
Feeding habits and microhabitat utilization by two syntopic Brazilian Amazonian frogs (Hyla minuta and Pseudopaludicula sp. (gr. falcipes)
Revista Brasileira de Biologia , 1998,
Abstract: We studied the feeding habits and microhabitat use of the Amazonian frogs Hyla minuta and Pseudopaludicula sp. at Serra Norte, Carajás, Brazil. Although living syntopically, the two species differed markedly in both prey types and sizes. Standardized feeding niche breadth of H. minuta (Bst = 0.572) was larger than that of Pseudopaludicula sp. (Bst = 0.149) and their feeding niche overlap was considerably low (10.5%). The two frog species also differed in microhabitat use. When active, Pseudopaludicula sp. were found partially submerged at the lake border whereas H. minuta were found predominantly on Nymphaea sp. leaves. Although we have not evaluated taxonomic effects on diet composition, differences in diet may be partially explained by differences in microhabitat use and frogs' size.
Introduction of a Wiki in an Enterprise: Motives and Challenges
Fernando L. F. Almeida,Rosa M. Rocha
Journal of Systems Integration , 2011,
Abstract: Among the tools available to implement the collaborative production of knowledge in organizations, the use of wikis has been gaining momentum and showing a low-cost and high efficiency. However, some difficulties still arise when attempting to introduce this kind of technology in an organization. In addition to technological limitations, the cultural issues inherent in companies can also origin problems and promising projects can be abandoned without achieving all the objectives planned. In this work, we study the motives, challenges as well as the more common problems that appear during the wiki implantation process in an organization and the purposed solutions on the literature. The main objective is to identify forms for the wiki to become a tool that everyone can use in the organization and identify the best practices related, so that the project of creating a functional wiki for an organization can aspire to befall a success and not simply abandoned.
Amphibia, Anura, restinga of Baixada do Maciambu, municipality of Palhoca, state of Santa Catarina, southern Brazil.
Wachlevski, M.,Rocha, C. F. D.
Check List , 2010,
Abstract: Little is known about amphibian communities on Brazilian restingas (coastal sand dune scrublands). This studypresents a first approximation to the list of anuran species from the restinga of Baixada do Maciambu, Santa Catarina,southern Brazil. We sampled using three methods (pitfall traps with drift fences, transect of active search, and surveys atbreeding sites) from July 2007 to April 2010. We recorded 15 species in six families, of which Hylidae was representedby the greatest number of species. Compared to other Brazilian restinga habitats, the species richness we recorded at theBaixada do Maciambu is similar to that reported for restingas of Rio de Janeiro state, but lower than that reported forrestingas in S o Paulo, Rio Grande do Sul and Bahia states, Brazil.
Is angiography still the best method to stratify stroke risk in symptomatic atherosclerotic carotid plaque?  [PDF]
Gustavo W. Kuster, A. J. Da Rocha, A. S. F. Silva, R. A. Valiente, M. S. G. Rocha, A. R. Massaro
Case Reports in Clinical Medicine (CRCM) , 2013, DOI: 10.4236/crcm.2013.28124
Abstract: The degree of vessel lumen narrowing is an independent predictor of ischemic stroke. New developments in carotid plaque morphology imaging (MR, CT), may bring new insights to the relationship between carotid atherosclerotic disease and stroke risk. Our aim is to review the stroke risk in a symptomatic patient with moderate carotid stenosis by CT imaging and histopathology. A 72-year-old patient with low ABCD2 scores TIA and moderate left internal carotid stenosis (50% by carotid ultrasound), was discharged with an optimized medical therapy. Four months later, he presented an ischemic stroke in the left frontal area. Carotid angiography showed a 60% stenosis in the left-internal carotid artery with a regular surface. CT plaque imaging detected a thin fibrous cap with calcification and an intraplaque hemorrhage (high-risk plaque). These findings were confirmed in the histolopathological study of the atherosclerotic plaque performed after the endarterectomy. After 1 year of follow-up, the patient returned independently to his daily activities. We propose, in this study, the inclusion of noninvasive plaque imaging in the evaluation of acute TIA with moderate carotid stenosis to better select patients with higher risk of stroke recurrence.
Changes in parents' and self-reports of behavioral problems in Brazilian adolescents after behavioral treatment with urine alarm for nocturnal enuresis
Rocha, Marina M.;Costa, Noel J.;Silvares, Edwiges F. M.;
International braz j urol , 2008, DOI: 10.1590/S1677-55382008000600010
Abstract: purpose: compare parents' reports of youth problems (pryp) with adolescent problems self-reports (apsr) pre/post behavioral treatment of nocturnal enuresis (ne) based on the use of a urine alarm. materials and methods: adolescents (n = 19) with mono-symptomatic (primary or secondary) nocturnal enuresis group treatment for 40 weeks. discharge criterion was established as 8 weeks with consecutive dry nights. pryp and apsr were scored by the child behavior checklist (cbcl) and youth self-report (ysr). results: pre-treatment data: 1) higher number of clinical cases based on parent report than on self-report for internalizing problems (ip) (13/19 vs. 4/19), externalizing problems (ep) (7/19 vs. 5/19) and total problem (tp) (11/19 vs. 5/19); 2) mean pryp scores for ip (60.8) and tp (61) were within the deviant range (t score ≥ 60); while mean pryp scores for ep (57.4) and mean apsr scores (ip = 52.4, ep = 49.5, tp = 52.4) were within the normal range. difference between pryp' and apsr' scores was significant. post treatment data: 1) discharge for majority of the participants (16/19); 2) reduction in the number of clinical cases on parental evaluation: 9/19 adolescents remained within clinical range for ip, 2/19 for ep, and 7/19 for tp. 3) all post-treatment mean scores were within the normal range; the difference between pre and post evaluation scores was significant for pryp. conclusions: the behavioral treatment based on the use of urine alarm is effective for adolescents with mono-symptomatic (primary and secondary) nocturnal enuresis. the study favors the hypothesis that enuresis is a cause, not a consequence, of other behavioral problems.
Biodiversity assessment of benthic macroinvertebrates along a reservoir cascade in the lower S?o Francisco river (northeastern Brazil)
Callisto, M.;Goulart, M.;Barbosa, F. A. R.;Rocha, O.;
Brazilian Journal of Biology , 2005, DOI: 10.1590/S1519-69842005000200006
Abstract: in order to verify the cascade-system effect in benthic macroinvertebrate communities, and the implications for policy making and proposals for conservation and sustainable use of the lower portion of s?o francisco river basin (bahia state, brazil), a three-reservoir cascade system including two stretches downstream were studied during dry (june, 1997) and rainy (march, 1998) periods. the dominant groups found were mollusca (melanoides tuberculata), oligochaeta, and chironomidae larvae. low shannon-wiener and pielou index values were found, but with no significant difference between the sampling periods. however, density and taxonomic richness were significantly different (t(0.05; 31) = -2.1945; p < 0.05; e t(0.05; 31) = -3.0600; p < 0.01) between the sampling periods, with a reduction in the number of taxaand macroinvertebrate abundance during the rainy period. an increasing gradient in benthic macroinvertebrate community structures was noted along the reservoir cascade from the first reservoir (apol?nio sales), followed by a decrease downstream from the third reservoir of the system (xingó). despite the negative consequences of rapid proliferation of dams, which have caused widespread loss of freshwater habitats, the reservoir cascade system promoted an increase in benthic macroinvertebrate diversity, due to water-quality improvement along the system.
Natural history of the lizard Enyalius brasiliensis (Lesson, 1828) (Leiosauridae) from an Atlantic Forest of southeastern Brazil
Van Sluys, M.;Ferreira, V. M.;Rocha, C. F. D.;
Brazilian Journal of Biology , 2004, DOI: 10.1590/S1519-69842004000200021
Abstract: information on the ecology of lizard species from the brazilian atlantic forest is scarce and almost nothing is known about the ecology of lizards of the genus enyalius. in this study, we provide information about some aspects of the natural history of e. brasiliensis from an area of atlantic forest in ilha grande, rj. enyalius brasiliensis (n = 15) feeds mainly on arthropods. the most frequent food items were insect larvae, orthopterans, and ants; in terms of volume, larvae and termites were the most important food items; ants and termites were the most numerous prey categories. two females were reproductive (one had 10 and the other, five vitellogenic follicles); the smallest measured 92.4 mm in svl. seven lizards were found on forest leaf litter. the other microhabitats used were vines, fallen logs, branches, and a crevice on a slope.
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