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Search Results: 1 - 10 of 241492 matches for " F. Cosío "
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Hematoma epidural secundario a anestesia espinal: Tratamiento conservador Epidural hematoma secondary to spinal anesthesia: Conservative treatment
M. Bermejo,E. Casta?ón,P. Fervienza,F. Cosío
Revista de la Sociedad Espa?ola del Dolor , 2004,
Abstract: Introducción: El hematoma epidural secundario a una anestesia neuroaxial es una complicación poco frecuente, pero de gran trascendencia tanto por sus implicaciones clínicas como por las médico legales; según algunos autores su incidencia puede oscilar entre 1/190.000-1/200.000 para las punciones peridurales y 1/320.000 en el caso de las espinales. El aspecto prioritario en su manejo terapéutico es el del diagnóstico y tratamiento precoz, antes de las 6-12 primeras horas. No obstante, en determinados pacientes como en el caso que presentamos puede no ser precisa la cirugía, resolviéndose el cuadro con tratamiento conservador. Caso clínico: Varón de 73 a os, ASA IV, con antecedentes de cirrosis con hipertensión portal, hiperesplenismo, EPOC, obesidad, cardiopatía hipertensiva e insuficiencia tricuspídea. Se programa para alcoholización prostática al haber sido desechada la cirugía. En la analítica preoperatoria destacaba una actividad de protrombina del 80% y 90.000 plaquetas. Se realizaron varios intentos fallidos de punción espinal, finalmente fue precisa una anestesia general con ventilación espontánea mediante mascarilla laríngea, propofol, fentanilo y sevoflurano. A las 36 horas, comienza la clínica en forma de dolor intenso lumbar, sin irradiación y arreflexia cutáneo plantar, confirmándose en la RMN la presencia de un hematoma epidural de L1 a L4. Ante la ausencia de paraparesia flácida, afectación esfinteriana u otros signos sensitivo-motores y tras consulta con la Unidad de Raquis y con el Servicio de Neurología se decide tratamiento conservador y actitud expectante en forma de analgesia y monitorización neurológica estricta, clínica y radiológica. Evolucionando favorablemente en los siguientes días. Discusión: Determinadas condiciones clínicas pueden influir en la aparición de un hematoma tras la realización de un bloqueo regional central: heparinas de bajo peso molecular, punciones dificultosas, cirugía vertebral previa, hepatopatías, fármacos, etc. El tratamiento quirúrgico en forma de laminectomía descompresiva realizada de forma precoz suele ser necesario y es el tratamiento de elección en muchas ocasiones, pero en determinadas condiciones como la que nos ocupa, sin síntomas compresivos, sin un carácter progresivo o bien que estos disminuyan rápidamente, puede optarse por un tratamiento conservador en forma de analgesia y corticoterapia, siempre bajo un estricto control que permita actuar de forma rápida ante cualquier eventualidad negativa en su evolución. Introduction: Epidural hematoma secondary to neuroaxial anesthesia is a rare complicat
Aportaciones desde México a la síntesis asimétrica y al análisis conformacional de moléculas
Eusebio Juaristi Cosío
Revista de la Sociedad Química de México , 1996,
Abstract:
Hematoma epidural secundario a anestesia espinal: Tratamiento conservador
Bermejo,M.; Casta?ón,E.; Fervienza,P.; Cosío,F.; Carpintero,M.; Díaz-Fernández,M. L.;
Revista de la Sociedad Espa?ola del Dolor , 2004,
Abstract: introduction: epidural hematoma secondary to neuroaxial anesthesia is a rare complication, but highly relevant due to its clinical and medico-legal implications. according to some authors, its incidence can reach 1/190,000-1/200,000 for peridural punctures and 1/320,000 for spinal punctures. early diagnosis and treatment within the first 6-12 hours is the main aspect related to its therapeutic management. however, in some cases such as the one reported here, surgery is not required and the patient can be managed with a conservative treatment. clinical case: a 73-year-old patient, asa iv, with a history of cirrhosis associated to portal hypertension, hypersplenism, copd, obesity, hypertensive cardiopathy and tricuspid failure. he was scheduled for prostate alcoholization after ruling out surgery. preoperative blood analyses showed a prothrombin activity of 80% and 90,000 platelets. several failed attempts of spinal puncture were done, but general anesthesia was finally required with spontaneous ventilation through laryngeal mudpack, propofol, fentanyl and sevoflurane. clinical manifestations appeared after 36 hours, with non-irradiated severe lumbar pain and plantar cutaneous areflexia. the presence of epidural hematoma at the l1-l4 level was confirmed through nmr. given the absence of flaccid paraparesis, sphincter involvement or other sensitive-motor signs and after consultation with the rachis unit and the neurology service, a conservative treatment and an expecting attitude were agreed based on analgesia and strict neurological monitoring, both clinical and radiological. the evolution of the patient was favorable in the next days. discussion: certain clinical conditions can affect the appearance of hematoma after performing a central regional blockade: low molecular weight heparins, difficult punctures, previous vertebral surgery, hepatopathies, drugs, etc. early surgical treatment based on decompression laminectomy is usually required and it is the treatment agr
Tratamiento de la obstrucción del conducto lacrimal con el stent Tear-Leader
Ferrer,D.; Esteban,E.; Aparisi,P.; Cosín,O.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2009, DOI: 10.4321/S0365-66912009001000006
Abstract: purpose: to compare the effectiveness and patency of the tearleader stent (pbn) for treatment of lacrimal system obstruction. methods: a prospective study of 68 patients referred from the ophthalmology department with suspicion of lacrimal system obstruction. we placed 74 tearleader pbn stents. inclusion criteria were: complete obstruction of lacrimal duct with canalicula and lacrimal puncta patency, and absence of acute infection. we studied the clinical improvement by means of an opinion survey, and the patency of stents was evaluated with kaplan-meier survival curves. results: follow-up of patients was two years. a painful procedure was reported in 10% of cases. minor dacryocystitis appeared in 18.9% of cases, while complete resolution of epiphora was confirmed in 77% of cases (23% of cases showed grade i epiphora). patency of stents: median patency 490 days (15 months), range 11 to 730 days; 1 year after stent placement patency was 0.51 and long term patency rate for 2 years was 0.31. opinion survey of the 68 patients: satisfaction with the technique, the procedure and prosthesis placement was 41%; satisfaction whilst the stent remained patent was 60.8%. conclusion: tearleader stent placement is easy to perform and comfortable for patients. tearleader placement gave a patency outcome similar to other stents.
Regionalised spatiotemporal rainfall and temperature models for flood studies in the Basque Country, Spain
P. Cowpertwait,D. Ocio,G. Collazos,O. de Cos
Hydrology and Earth System Sciences Discussions , 2012, DOI: 10.5194/hessd-9-10365-2012
Abstract: A spatial-temporal point process model of rainfall is fitted to data taken from three homogeneous regions in the Basque Country, Spain. The model is the superposition of two spatial-temporal Neyman-Scott processes, in which rain cells are modelled as discs with radii that follow exponential distributions. In addition, the model includes a parameter for the radius of storm discs, so that rain only occurs when both a cell and a storm disc overlap a point. The model is fitted to data for each month, taken from each of the three homogeneous regions, using a modified method of moments procedure that ensures a smooth seasonal variation in the parameter estimates. Daily temperature data from twenty three sites are used to fit a stochastic temperature model. A principal component analysis of the maximum daily temperatures across the sites indicates that 92% of the variance is explained by the first component, implying that this component can be used to account for spatial variation. A harmonic equation with autoregressive error terms is fitted to the first principal component. The temperature model is obtained by regressing the maximum daily temperature on the first principal component, an indicator variable for the region, and altitude. This, together with scaling and a regression model of temperature range, enables hourly temperatures to be predicted. Rainfall is included as an explanatory variable but has only a marginal influence when predicting temperatures. A distributed model (TETIS; Francés et al., 2007) is calibrated for a selected catchment. Five hundred years of data are simulated using the rainfall and temperature models and used as input to the calibrated TETIS model to obtain simulated discharges to compare with observed discharges. Kolmogorov-Smirnov tests indicate that there is no significant difference in the distributions of observed and simulated maximum flows at the same sites, thus supporting the use of the spatiotemporal models for the intended application.
Tratamiento de la obstrucción del conducto lacrimal con el stent Tear-Leader Treatment of lacrimal duct obstruction with a Tear-Leader stent
D. Ferrer,E. Esteban,P. Aparisi,O. Cosín
Archivos de la Sociedad Espa?ola de Oftalmología , 2009,
Abstract: Objetivo: Describir los resultados clínicos y estudiar la permeabilidad del stent de Tear-Leader (PBN) en el tratamiento de la obstrucción del conducto lacrimal. Método: Estudio prospectivo de 68 pacientes, remitidos desde el Servicio de Oftalmología para estudio de epífora por sospecha de obstrucción del conducto lacrimal. Hemos colocado un total de 74 stents Tear-Leader. Los criterios de inclusión fueron: obstrucción completa del conducto lacrimal con permeabilidad de canalículos y de puntos lacrimales así como ausencia de infección aguda. Hemos realizado en todos los pacientes el control clínico y una encuesta de satisfacción. Se realizó un estudio estadístico descriptivo y se evaluó la permeabilidad de la prótesis usando las curvas de Kaplan Meier. Resultados: El seguimiento de los pacientes se realizó durante dos a os. Se confirmó la resolución total de la epífora en el 77%, (en el 23% persistió una epífora grado I). Permeabilidad del stent: la mediana fue de 490 días (15 meses) con rango de 11-730 días, al a o la permeabilidad fue de 0,51 y a 2 a os de 0,31. Refieren implantación dolorosa el 10% de los casos implantados. Aparecieron episodios de dacriocistitis leve en el 18% de los casos. Encuesta de satisfacción a los 68 pacientes: con respecto a la técnica, procedimiento y prótesis estaban satisfechos un 41%. Mientras la prótesis se mantuvo permeable se encontraban satisfechos un 60,8%. Conclusión: La prótesis Tear-Leader es de fácil colocación, con escasas molestias para el paciente. Presenta una permeabilidad similar al resto de stents del mercado. Purpose: To compare the effectiveness and patency of the TearLeader stent (PBN) for treatment of lacrimal system obstruction. Methods: A prospective study of 68 patients referred from the ophthalmology department with suspicion of lacrimal system obstruction. We placed 74 TearLeader PBN stents. Inclusion criteria were: complete obstruction of lacrimal duct with canalicula and lacrimal puncta patency, and absence of acute infection. We studied the clinical improvement by means of an opinion survey, and the patency of stents was evaluated with Kaplan-Meier survival curves. Results: Follow-up of patients was two years. A painful procedure was reported in 10% of cases. Minor dacryocystitis appeared in 18.9% of cases, while complete resolution of epiphora was confirmed in 77% of cases (23% of cases showed grade I epiphora). Patency of stents: median patency 490 days (15 months), range 11 to 730 days; 1 year after stent placement patency was 0.51 and long term patency rate for 2 years was 0.31. Opinion su
Dual-Band Antenna/AMC Combination for RFID
M. E. de Cos,F. Las-Heras
International Journal of Antennas and Propagation , 2012, DOI: 10.1155/2012/804536
Abstract: A novel antenna/Artificial Magnetic Conductor (AMC) combination usable in dual-band Radio Frequency Identification (RFID) tags over metallic objects is presented. A compact and low thickness prototype is manufactured and characterized in terms of return loss and radiation properties in an anechoic chamber both alone and on a metallic plate. The performance exhibited by the presented antenna/AMC prototype is proper for RFID tags on both metallic and nonmetallic objects.
Novel Flexible Artificial Magnetic Conductor
M. E. de Cos,F. Las-Heras
International Journal of Antennas and Propagation , 2012, DOI: 10.1155/2012/353821
Abstract: A novel flexible uniplanar AMC design is presented. An AMC prototype is manufactured using laser micromachining and it is characterized under flat and bent conditions by measuring its reflection coefficient phase in an anechoic chamber. The designed prototype shows broad AMC operation bandwidth (6.96% and higher) and polarization angle independency. Its angular stability margin, when operating under oblique incidence, is also tested obtaining ±8° as limit for a 14.4 cm × 14.4 cm prototype.
Study of Antiparasitic and Cytotoxicity of the Aqueous, the 80% Methanol Extract and Its Fractions, and the Acute Toxicity of the Aqueous Extract of Brucea sumatrana (Simaroubaceae) Leaves Collected in Mai-Ndombe, Democratic Republic of Congo  [PDF]
M. Tshodi Ehata, S. Nsaka Lumpu, C. Kikweta Munduku, O. Kambu Kabangu, P. Cos, L. Maes, S. Apers, A. J. Vlietinck, L. Pieters, R. Cimanga Kanyanga
Chinese Medicine (CM) , 2016, DOI: 10.4236/cm.2016.73011
Abstract: Results from the in vitro evaluation of the antiparasitaire activity of the aqueous extract, the 80% methanol extract and its fractions from the leaves of Brucea sumatrana against Trypanosoma brucei brucei, T. cruzi, Leishmania infantum, the multidrug-resistant K1 and chloroquine-sensitive NF54 strains of Plasmodium falciparum indicated that all samples from the leaves extract presented interesting antiparasitaire activity at different extents. The 80% methanol extract, its chloroform acid, petroleum ether and 80% methanol soluble fractions and the aqueous extract exhibited strong activity against Trypanosoma b. brucei, T. cruzi, L. infantum and the multidrug-resistant K1 strain of P. falciparum with IC50 values from <0.25 to 4.35 μg/ml as well as against chloroquine-sensitive NF54 strain of P. falciparum with IC50 values ranging from <0.02 to 2.0.4 μg/ml. Most samples were cytotoxic against MRC-5 cell lines (0.2 < cytotoxic concentration 50(CC50) < 34.24 μg/ml) and showed good selective effect against all tested parasites. In acute toxicity, the aqueous extract was found to be non-toxic and its LD50 was estimated to be greater than 5
Regionalised spatiotemporal rainfall and temperature models for flood studies in the Basque Country, Spain
P. Cowpertwait, D. Ocio, G. Collazos, O. de Cos,C. Stocker
Hydrology and Earth System Sciences (HESS) & Discussions (HESSD) , 2013,
Abstract: A spatiotemporal point process model of rainfall is fitted to data taken from three homogeneous regions in the Basque Country, Spain. The model is the superposition of two spatiotemporal Neyman–Scott processes, in which rain cells are modelled as discs with radii that follow exponential distributions. In addition, the model includes a parameter for the radius of storm discs, so that rain only occurs when both a cell and a storm disc overlap a point. The model is fitted to data for each month, taken from each of the three homogeneous regions, using a modified method of moments procedure that ensures a smooth seasonal variation in the parameter estimates. Daily temperature data from 23 sites are used to fit a stochastic temperature model. A principal component analysis of the maximum daily temperatures across the sites indicates that 92% of the variance is explained by the first component, implying that this component can be used to account for spatial variation. A harmonic equation with autoregressive error terms is fitted to the first principal component. The temperature model is obtained by regressing the maximum daily temperature on the first principal component, an indicator variable for the region, and altitude. This, together with scaling and a regression model of temperature range, enables hourly temperatures to be predicted. Rainfall is included as an explanatory variable but has only a marginal influence when predicting temperatures. A distributed model (TETIS; Francés et al., 2007) is calibrated for a selected catchment. Five hundred years of data are simulated using the rainfall and temperature models and used as input to the calibrated TETIS model to obtain simulated discharges to compare with observed discharges. Kolmogorov–Smirnov tests indicate that there is no significant difference in the distributions of observed and simulated maximum flows at the same sites, thus supporting the use of the spatiotemporal models for the intended application.
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