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Search Results: 1 - 10 of 145185 matches for " F. Bosch "
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Epidemiology of human papillomavirus infections: new options for cervical cancer prevention
Bosch,F. Xavier;
Salud Pública de México , 2003, DOI: 10.1590/S0036-36342003000900006
Abstract: in the last two decades, the cervical cancer puzzle has become a coherent description that includes the identification of human papillomavirus (hpv) as the sexually transmitted etiologic agent and the characterization of the major determinants of hpv acquisition. triage studies have consistently shown that hpv testing is more sensitive that repeated cytology in identifying underlying high-grade lesions in women with atypical scamous cells of undetermined significance (ascus). studies that reflect primary screening conditions have shown that the sensitivity of hpv tests is higher than standard cytology in detecting high-grade lesions whereas the specificity is similar only in women aged 30-35 and above. hpv vaccines have an intrinsic attraction as a preventive strategy in populations with limited resources. however, vaccines designed to widespread use are still in development and testing phases. time is ripe for exploring in depth the clinical implications of current achievements and to devise novel strategies for the prevention of cervical cancer.
Cáncer cervical: avances en la prevención y conocimiento de su etiología
Bosch F Xavier
Salud Pública de México , 2003,
Abstract:
Epidemiology of human papillomavirus infections: new options for cervical cancer prevention
Bosch F. Xavier
Salud Pública de México , 2003,
Abstract: In the last two decades, the cervical cancer puzzle has become a coherent description that includes the identification of human papillomavirus (HPV) as the sexually transmitted etiologic agent and the characterization of the major determinants of HPV acquisition. Triage studies have consistently shown that HPV testing is more sensitive that repeated cytology in identifying underlying high-grade lesions in women with atypical scamous cells of undetermined significance (ASCUS). Studies that reflect primary screening conditions have shown that the sensitivity of HPV tests is higher than standard cytology in detecting high-grade lesions whereas the specificity is similar only in women aged 30-35 and above. HPV vaccines have an intrinsic attraction as a preventive strategy in populations with limited resources. However, vaccines designed to widespread use are still in development and testing phases. Time is ripe for exploring in depth the clinical implications of current achievements and to devise novel strategies for the prevention of cervical cancer.
Der javanische Mangsakalender
F. van den Bosch
Bijdragen tot de Taal-, Land- en Volkenkunde , 1980,
Abstract:
Publicaciones gratuitas sobre comunicación científica: aportaciones desde una fundación
Fèlix Bosch
Panace@ : Revista de Medicina, Lenguaje y Traducción , 2003,
Abstract:
Demanda de formación en profesionales sanitarios Demand for training within the health care profession
F. Bosch,E. Serés
Educación Médica , 2010,
Abstract:
Tendiendo puentes: la utilidad de la historia de la ciencia para comprender el proceso de investigación y desarrollo de medicamentos
Bosch,F.; Ba?os,J.E.;
Educación Médica , 2010, DOI: 10.4321/S1575-18132010000400008
Abstract: introduction. traditionally, social and experimental sciences have followed different paths, which have led to the creation of an artificial separation between them. one of the clearest examples that has tried to avoid this situation is the creation of disciplines such as the history of science, which helps to bring both closer together. however, the perception among scientists regarding the interest of history is not optimal, despite the undoubted virtues that the latter contains. materials and methods. in this article the experience of using historical events to contribute to learning of complex processes, such as research and development of new drugs, is described. the use of two cases is outlined that were successfully completed and awarded the nobel prize: the modification of neurotransmitters′ structure to obtain new drugs (emasculated hormones) by james black, and the application of the antimetabolite concept to design drugs for infectious, cancer and endocrine diseases. conclusion. a teaching approach is remarkably successful in helping students understand the complexities of research and drug development.
Cervical cancer and human papillomavirus: Epidemiological evidence and perspectives for prevention
MU?OZ,NUBIA; BOSCH,F. XAVIER;
Salud Pública de México , 1997, DOI: 10.1590/S0036-36341997000400005
Abstract: cervical cancer is a major public health problem, as it is the second most common cancer in women world-wide after breast cancer. about 80% of the half a million cases estimated to occur annually in the world, occur in developing countries. the epidemiological evidence linking human papillomavirus (hpv) to cervical cancer is reviewed. it is concluded that over 90% of cervical cancers can be attributed to certain hpv types. hpv 16 accounts for the highest proportion (50%) followed by hpv 18 (12%), hpv 45 (8%) and hpv 31 (5%). the associations with these hpv types are very b and consistent with odds ratios over 15 in all case-control studies in high- and low-risk countries for cervical cancer. however, hpv is not a sufficient cause of this malignancy; certain cofactors are necessary for a proportion of hpv persistent infections to eventually progress to cancer. these include host factors such as histocompatibilidad types and immunological response, hormonal influences and infections with other sexually transmitted agents such as chlamydia trachomatis. in addition, results from our studies carried out in spain and colombia support the hypothesis that male carriers of hpv play an important role in the development of cervical cancer in their wives. the recognition of the central role of hpv in cervical cancer has far-reaching implications for the primary and secondary prevention of this malignancy. prophylactic and therapeutic hpv vaccines are now under development and hpv typing is being integrated into screening programmes in pilot studies in a few developed countries. in developing countries, well conducted conventional screening programmes remain the best approach for the control of cervical cancer until a safe and efficient hpv vaccine can be used in the general population.
C.C. Berg and ancient Javanese history
F.D.K. Bosch
Bijdragen tot de Taal-, Land- en Volkenkunde , 1956,
Abstract:
De Asvin-Goden en de Epische tweelingen in de Oudjavaanse kunst en literatuur
F.D.K. Bosch
Bijdragen tot de Taal-, Land- en Volkenkunde , 1967,
Abstract:
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