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Search Results: 1 - 10 of 5760 matches for " Eva; Arteaga "
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Las histiocitosis
Svarch,Eva; Arteaga,Rafael; Pavón Morán,Valia; González Otero,Alejandro;
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2001,
Abstract: the term histiocytosis identifies a group of disorders that have in common the proliferation of dentritic cells (dc) and macrophages and is frequently diagnosed in children. among the fundamental variants of histiocytosis related with dc, we find langerhans cell histiocytosis (lch). langerhans cell histiocytosis has very variable clinical behavior that ranges from a lesion involving only one site or system to a multisystem disease. treatment depends on the spread of the process. an only lesion tends to spontaneously disappear. also diagnostic biopsy with or without steroid injection may lead to healing. those patients with multisystem disease may benefit from an steroid and cytostatic-based treatment or even from progenitor hematopoietic cell transplantation. sinus histiocytosis with massive lymphadenopathies or rosai dorfman disease is a benign and usually self-limited disease which is caused by the macrophage proliferation; it generally affects children and young adults. hemophagocytic lymphohistiocytosis is also caused by macrophage proliferation and is a rare disease with a high mortality rate. it can be familiar hemophagocytic lymphohistiocytosis (recessive autosomal) or secondary to viral infections, being the latter form the most frequent in infants. at present, mainly in the familiar variant, the progenitor hematopoietic allogenic transplant may serve as the only curative option
Las histiocitosis Histiocytosis
Eva Svarch,Rafael Arteaga,Valia Pavón Morán,Alejandro González Otero
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2001,
Abstract: El término histiocitosis identifica un grupo de alteraciones que tienen en común la proliferación de células dendríticas (CD) y los macrófagos, y se diagnostican más frecuentemente en ni os. Dentro de las relacionadas con las CD las fundamentales son las histiocitosis a células de Langerhans (HCL). Las HCL tienen un comportamiento clínico muy variable, que puede ir desde una lesión que involucra un solo sitio o sistema hasta una enfermedad multisistémica. El tratamiento depende de la extensión del proceso. Una lesión única tiende a desaparecer espontáneamente. También la biopsia diagnóstica con o sin inyección de un esteroide puede iniciar la curación. Los pacientes con enfermedad multisistémica pueden beneficiarse con el tratamiento esteroideo y citostático o inclusive con el trasplante de células progenitoras hematopoyéticas. La histiocitosis sinusal con linfoadenopatías masivas o enfermedad de Rosai Dorfman se debe a la proliferación de los macrófagos, es de naturaleza benigna y usualmente autolimitada. Afecta sobre todo a ni os y adultos jóvenes. La linfohistiocitosis hemofagocítica también se produce por la proliferación de los macrófagos y es una enfermedad rara con una alta mortalidad. Puede ser familiar (autosómica recesiva) o secundaria a infecciones virales. Esta última forma se presenta más frecuentemente en el lactante peque o. En la actualidad, sobre todo en la variedad familiar, el trasplante alogénico de células progenitoras hematopoyéticas puede ser la única medida curativa The term histiocytosis identifies a group of disorders that have in common the proliferation of dentritic cells (DC) and macrophages and is frequently diagnosed in children. Among the fundamental variants of histiocytosis related with DC, we find Langerhans cell histiocytosis (LCH). Langerhans cell histiocytosis has very variable clinical behavior that ranges from a lesion involving only one site or system to a multisystem disease. Treatment depends on the spread of the process. An only lesion tends to spontaneously disappear. Also diagnostic biopsy with or without steroid injection may lead to healing. Those patients with multisystem disease may benefit from an steroid and cytostatic-based treatment or even from progenitor hematopoietic cell transplantation. Sinus histiocytosis with massive lymphadenopathies or Rosai Dorfman disease is a benign and usually self-limited disease which is caused by the macrophage proliferation; it generally affects children and young adults. Hemophagocytic lymphohistiocytosis is also caused by macrophage proliferation and is a rare dise
The Difficult Airway: A New Simplified Approach to an Old Complex Problem  [PDF]
Iván Mauricio Alvarado Arteaga
Open Journal of Anesthesiology (OJAnes) , 2017, DOI: 10.4236/ojanes.2017.78023
Abstract: Difficult airway situations are a major cause of morbidity, mortality and malpractice claims in anesthetic practice and other critical care settings. Although infrequent, they are serious and complex situations where many variables interact. Among these variables, quick and accurate rescuer decision-making is a major outcome determinant. Emerging evidence, recent advances in technology and development of new devices have provided new tools to deal with the problem, but still, basic underlying principles of management remain. Based on the available evidence and expert consensus, multiple guidelines and algorithms have been published, but they may have limited applicability, contain confusing and ambiguous recommendations or address very specific clinical situations. This narrative review attempts to summarize, organize and consolidate current trends and supported recommendations of the updated guidelines in one practical, concise and unified guide, proposing a simple, intuitive and novel algorithm.
Quantum Brownian Representation for the Quantum Field Modes
Daniel Arteaga
Advances in High Energy Physics , 2009, DOI: 10.1155/2009/278759
Abstract: When analyzing the particle-like excitations in quantum field theory it is natural to regard the field mode corresponding to the particle momentum as an open quantum system, together with the opposite momentum mode. Provided that the state of the field is stationary, homogeneous, and isotropic, this scalar two-mode system can be equivalently represented in terms of a pair of quantum Brownian oscillators under a Gaussian approximation. In other words, the two-mode system behaves as if it were interacting linearly with some effective environment. In this paper we build the details of the effective linear coupling and the effective environment, and argue that this quantum Brownian representation provides a simple, universal, and nonperturbative characterization of any single particle-like excitation. As immediate applications of the equivalence, we reanalyze the interpretation of the self-energy in terms of decay rates in a general background state and present the master equation for the field mode corresponding to the particle momentum.
The phosphatidylinositol-3 kinase/mTOR pathway: new agents
CL Arteaga
Breast Cancer Research , 2011, DOI: 10.1186/bcr3007
Abstract: Class IA PI3K isoforms are heterodimeric lipid kinases that contain a p110 catalytic subunit and a p85 regulatory subunit. The three genes PIK3CA, PIK3CB, and PIK3CD encode the homologous p110α, p110β, and p110δ isozymes, respectively. Expression of p110δ is largely restricted to immune and hematopoietic cells, whereas p110α and p110β are ubiquitously expressed. p110α is essential for signaling and growth of tumors driven by PIK3CA mutations, RTKs, and/or mutant Ras, whereas p110β lies downstream of GPCRs and has been shown to mediate tumorigenesis in PTEN-deficient cells. PIK3CA mutations are the most commonly known genetic alterations of this pathway in cancer, where ≥80% occur within the helical (E542K and E545K) and kinase (H1047R) domains of p110α. Such mutations confer increased catalytic activity through different mechanisms, but both induce characteristics of cellular transformation including growth factor-independent and anchorage-independent growth, and resistance to anoikis.Several drugs targeting multiple levels of the PI3K network (that is, PI3K, AKT, mTOR) have been developed. A number of ATP-mimetics that bind competitively and reversibly to the ATP-binding pocket of p110 are in early clinical development. These include the pan-PI3K inhibitors BKM120, XL-147, PX-866, PKI-587, and GDC-0941, the p110α-specific inhibitors BYL719, GDC-0032, and INK-1117, the p110δ-specific inhibitor CAL-101, and the dual PI3K/mTOR inhibitors BEZ235, BGT226, PF-4691502, GDC-0980, and XL-765. The pan-PI3K and p110α-specific inhibitors are equally potent against oncogenic p110α mutants. The rationale for the development of isozyme-specific antagonists is to allow higher doses of anti-p110α and anti-p110β drugs to be delivered without incurring side effects caused by pan-PI3K inhibitors. Interim results from a phase I trial with the p110δ-specific inhibitor CAL-101 in patients with hematologic malignancies showed that treatment reduced P-AKT levels >90% in peripheral blood ly
Particle propagation in non-trivial backgrounds: a quantum field theory approach
Arteaga, Daniel
High Energy Physics - Phenomenology , 2007,
Abstract: The basic aim of the thesis is the study of the propagation of particles and quasiparticles in non-trivial backgrounds from the quantum field theory point of view. By "non-trivial background" we mean either a non-vacuum state in Minkowski spacetime or an arbitrary state in a curved spacetime. Starting with the case of a flat spacetime, the basic properties of the particle and quasiparticle propagation are analyzed using two different methods other than the conventional mean-field-based techniques: on the one hand, the quantum state corresponding to the quasiparticle excitation is explicitly constructed; on the other hand, the spectral representation of the two-point propagators is analyzed. Both methods lead to the same results: the energy and decay rate of the quasiparticles are determined by the real and imaginary parts of the retarded self-energy respectively. These general results are applied to two particular quantum systems: first, a scalar particle immersed in a thermal graviton bath; second, a simplified atomic model, seizing the opportunity to connect with other statistical and first-quantized approaches. In the second part of the thesis the results are extended to curved spacetime. Working with a quasilocal quasiparticle concept the flat-spacetime results are recovered. In cosmology, within the adiabatic approximation, it is possible to go beyond the flat spacetime results and find additional effects due to the universe expansion. The cosmologically-induced effects are analyzed, obtaining that there might be an additional contribution to the particle decay due to the universe expansion. In the de Sitter case, this additional contribution coincides with the decay rate in a thermal bath in a flat spacetime at the corresponding de Sitter temperature.
LAS MEDICINAS TRADICIONALES EN LA PAMPA ARGENTINA
Facundo Arteaga
AIBR : Revista de Antropología Iberoamericana , 2010,
Abstract: In this article, the author claims that traditional medicines from La Pampa Argentina both laypractitioners and specialists or curanderos with therapeutic rituals, most of them with aCatholic origin. The author considers that some researchers have exaggerated the importanceof native’s knowledge and practice in traditional medicines. First, he analyses the influences ofancient biomedical conceptions for both specialists and lay practitioners, underlying theimportance of humoral medicine. Secondly, he focuses on spell or “healing by word”, thetypical lay’s therapeutic ritual, taking into account the meaning level. Finally, he explores thecurandero’s therapeutic ritual, distinguishing the techniques used for a few illnesses whichconsider generalized ritual procedures. The author constantly points out that therapeuticpractices and awareness, as well as etiological theories of illness are integrated in a Spanishand European rooted world-view.
Form-focused instruction in the French L2 classroom
Deborah Arteaga
Sintagma : Revista de Lingüística , 2009,
Abstract: This paper considers the integration of grammar within the communicative method of second language instruction. It discusses the acquisition of the masculine/feminine alternation of regular French adjectives, arguing that this grammatical feature should be taught to students by underscoring the regularity of adjective agreement in French. It then reviews twelve French first-year university-level textbooks popular in the U.S., noting that with two exceptions, they emphasize a Focus on Forms (individual paradigms) and not on form (the system behind the grammar). It concludes with suggestions on how textbooks could most effectively address the masculine/feminine dichotomy of French adjectives.
Una "lección de sociales": Representación de la ciudadanía transmitida en libros de texto de primaria venezolanos
Carmen Arteaga
Espacio Abierto , 2009,
Abstract: Se presentan resultados parciales de una investigación cualitativa sobre representaciones sociales -incluyendo la de ciudadanía-, en textos de primaria venezolanos, desde la perspectiva metodológica de análisis crítico del discurso, que considera acción al lenguaje, queopera como transmisor de patrones ideológicos. Se concluye que la ciudadanía representada es universal y democrática, aunque los partidospolíticos, instituciones naturales de la democracia, al estar cuestionados, no constituyen -discursivamente- una opción legítima de participación, aunque se contempla la organización comunitaria del ciudadano. También se "dibuja" cierta pasividad del ciudadano frente a personajes históricos y al liderazgo político, mostrados éstos como figuras épicas, sobrehumanas, lo cual coloca en plano de inferioridad al ciudadano común, en su capacidad para realizar acciones trascendentes en nuestra sociedad.
El trabajo de las mujeres policías
Nelson Arteaga
El Cotidiano , 2000,
Abstract: La policía se refuerza en México como una profesión masculina y, sin duda, las mujeres han tenido que enfrentar una serie de obstáculos desde los exámenes de admisión, que poseen un referente; centrado en destacar la fuerza más que otras aptitudes, hasta la propia permanencia en la academia y la vida profesional en la calle. En cada uno de estos espacios la mujer es relegada: durante la academia, la mujer es sometida a todo tipo de presiones de resistencia física y acoso sexual y en la calle se procura, principalmente, desplazarla hacia actividades consideradas por los propios policías como de segunda, como funciones administrativas y secretariales.
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