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Search Results: 1 - 10 of 8167 matches for " Eva Irene Falleth "
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Participation in planning – A study of urban development in Norway
Eva Irene Falleth,Gro Sandkj?r Hansen
European Journal of Spatial Development , 2011,
Abstract: In Norway, the dominance of neo-liberal ideas has resulted in a private planning practice whereby the developer is the principal actor in opaque negotiations between planning authorities and developers. We examine patterns of contact between stakeholders in urban development planning. Based on information obtained from a survey of the 145 most populous municipalities in Norway, as well as from case studies in Oslo, Bergen and Trondheim, we find considerable interaction between the stakeholders involved in the planning process. The interaction patterns are different for civil society actors and private developers. We find that while developers have contacts with the planning authorities, the civil actors have contacts with the politicians. In the initial phase, i.e. before formal planning begins, this pattern is highly significant. Politicians frequently feel bound by negotiations and agreements that are made by the planners and the developers during the initial planning process.
A Study on the Degradation of Carbamazepine and Ibuprofen by TiO2 & ZnO Photocatalysis upon UV/Visible-Light Irradiation  [PDF]
Irene Georgaki, Eva Vasilaki, Nikos Katsarakis
American Journal of Analytical Chemistry (AJAC) , 2014, DOI: 10.4236/ajac.2014.58060
Abstract: The degradation of carbamazepine (CBZ) and ibuprofen (IBP) in aqueous matrices was investigated by TiO2 and ZnO photocatalysis initiated by UV-A and visible-light irradiation. Emphasis was given on the effect of operating parameters on the degradation effectiveness, such as catalyst type and loading (50 - 500 mg/L), initial drug concentration (10, 40, 80 mg/L) and wavelength of irradiation (200 - 600 nm). In an effort to understand the photocatalytic pathway for CBZ and IBP removal in terms of primary oxidants, the contribution of HO· was evaluated. With this scope, the radical-mediated process was suppressed by addition of an alcohol scavenger, isopropanol, (i-PrOH), described as the best free hydroxyl radical quencher. The photodegradation rate of the pharmaceuticals was monitored by high performance liquid chromatography (HPLC). According to the results, visible-light exposure, at λexc > 390 nm, takes place as a pure photocatalytic degradation reaction for both compounds. IBP was found to have overall high conversion rates, compared to CBZ. IBP oxidized fast under photocatalytic conditions, regardless the adverse effect of the increase of initial drug concentration, or low catalyst load, irradiation upon visible-light, by either titania or zinc oxide. Finally, addition of isopropanol showed a significant inhibition effect on the CBZ degradation, taken as an evidence of a solution-phase mechanism. In the case though of IBP degradation, the hole mechanism may be prevailing, suggested by the negligible effect upon addition of isopropanol indicating a direct electron transfer between holes (h+) and surface-bound IBP molecules. A plausible mechanism of IBP and CBZ photocatalysis was proposed and described.
On the topology of nested set complexes
Eva Maria Feichtner,Irene Mueller
Mathematics , 2003,
Abstract: Nested set complexes appear as the combinatorial core of De Concini-Procesi arrangement models. We show that nested set complexes are homotopy equivalent to the order complexes of the underlying meet-semilattices without their minimal elements. For atomic semilattices, we consider the realization of nested set complexes by simplicial fans as proposed in math.AG/0305142 by the first author and S. Yuzvinsky. We show that in this case the nested set complexes in fact are homeomorphic to the mentioned order complexes.
Inhibition of E2-induced expression of BRCA1 by persistent organochlorines
Thomas Rattenborg, Irene Gjermandsen, Eva C Bonefeld-J?rgensen
Breast Cancer Research , 2002, DOI: 10.1186/bcr461
Abstract: Using human breast cancer cell lines MCF-7 and MDA-MB-231, the effect on BRCA1 expression of chemicals belonging to different classes of organochlorine chemicals (the pesticide toxaphene, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and three polychlorinated biphenyls [PCB#138, PCB#153 and PCB#180]) was measured by a reporter gene construct carrying 267 bp of the BRCA1 promoter. A twofold concentration range was analyzed in MCF-7, and the results were supported by northern blot analysis of BRCA1 mRNA using the highest concentrations of the chemicals.All three polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin reduced 17β-estradiol (E2)-induced expression as well as basal reporter gene expression in both cell lines, whereas northern blot analysis only revealed a downregulation of E2-induced BRCA1 mRNA expression in MCF-7 cells. Toxaphene, like E2, induced BRCA1 expression in MCF-7.The present study shows that some POCs have the capability to alter the expression of the tumor suppressor gene BRCA1 without affecting the cell-cycle control protein p21Waf/Cip1. Some POCs therefore have the potential to affect breast cancer risk.The incidence of breast cancer has been increasing steadily over the past 60 years [1], today affecting one in eight women in the United States [2]. Despite tremendous efforts to understand the disease, less than 50% of all cases are of known etiology such as genetic inheritance, first-degree relatives with breast cancer, and age of menstruation and menopause [3].A large group of lipophilic organochlorines are found to persist in the environment and to biomagnify through the food chain. This group includes pesticides, polychlorinated biphenyls (PCBs) and polychlorinated dibenzo-dioxins/polychlorinated dibenzo-furans [4-8]. Many of these compounds can interfere with a wide range of hormonal responses [9-13], including estrogen receptor (ER)-mediated responses. Due to their lipophilic nature, organochlorines accumulate in the adipose tissue,
Reliability and validity study of Persian modified version of MUSIC (musculoskeletal intervention center) – Norrtalje questionnaire
Akbar Alipour, Mostafa Ghaffari, Irene Jensen, Batoul Shariati, Eva Vingard
BMC Musculoskeletal Disorders , 2007, DOI: 10.1186/1471-2474-8-88
Abstract: The first step was to establish two expert panel groups in Iran and Sweden. The Focus Group Discussion (FGD) method was used to detect questionnaire face and content validity. To detect questionnaire reliability, we used the test-retest method.Except for two items, all other questions that respondents had problems with in the focus group (20 of 297), had unclear translations; the ambiguity was related to the stem of the questions and the predicted answers were clear for the participants. The concepts of 'household/spare time' and 'physical activity in the workplace' were not understood by the participants of FGD; this has been solved by adding further descriptions to these phrases in the translation. In the test-retest study, the reliability coefficient was relatively high in most items (only 5 items out of 297 had an ICC or kappa below 0.7).The findings from the present study provide evidence that the Persian version of the MUSIC questionnaire is a reliable and valid instrument.Musculoskeletal disorders (MSDs) are a major health problem in all countries [1]. They encompass a variety of conditions, including disorders of muscles, tendons and nerves. Although the underlying pathology of these conditions may differ and their diagnoses are unclear, the symptoms are often similar.There is no "golden standard" measurement tool for estimating the prevalence of MSDs among the population. Statistics on the prevalence of work-related musculoskeletal disorders may vary from one reference source to another, primarily due to variations in outcome measures, and the diagnostic criteria. A common method for estimating the magnitude of the problem is self-reported data in questionnaires concerning episodes of pain [2].Physical, organizational, psychosocial, and sociological factors at work can contribute to MSDs alone or in combination [3-5].The MUSIC-Norrtalje study from Sweden was performed to find health and risk factors for low back and neck/shoulder disorders in the general wo
Técnicas de Abordaje Psicológico en una Sala de Pediatría
Eva Giberti,Roberto Baretto,Irene Meler,Silvia Zeigner
Revista Latinoamericana de Psicología , 1970,
Abstract: Techiques of psychological study in a pediatric setting are described: (1) Psychological history. (2) Diagnostic play. (3) Battery of tests.(4) Interview with the mother. (5) Interview with both parents. (6) Interview with the family group. (7) Therapeutic games. (8) Training for operations. (8) Work with groups of mothers.
Sick leave among home-care personnel: a longitudinal study of risk factors
Eva L Horneij, Irene B Jensen, Eva B Holmstr?m, Charlotte Ekdahl
BMC Musculoskeletal Disorders , 2004, DOI: 10.1186/1471-2474-5-38
Abstract: Study group I, comprised 443 female nursing aides/assistant nurses, not on sick leave at baseline when a questionnaire was completed. Data on certified sick leave were collected after 18 months. Study group II comprised 274 of the women, who at baseline reported no sick leave during the preceding year due to NSBD and who participated at the 18 month follow-up. Data on sick leave due to NSBD were collected from the questionnaire at 18 months. The associations between future sick leave and factors related to health, work and leisure time were tested by logistic regression analyses.Health-related factors such as previous low back disorders (OR: 1.89; 95% CI 1.20–2.97) and previous sick leave (OR 6.40; 95%CI 3.97–10.31), were associated with a higher risk of future sick leave due to any cause. Factors related to health, work and leisure time, i.e. previous low back disorders (OR: 4.45; 95% CI 1.27–15.77) previous sick leave, not due to NSBD (OR 3.30; 95%CI 1.33–8.17), high strain work (OR 2.34; 95%CI 1.05–5.23) and high perceived physical exertion in domestic work (OR 2.56; 95%CI 1.12–5.86) were associated with a higher risk of future sick leave due to NSBD. In the final analyses, previous low back disorders and previous sick leave remained significant in both study groups.The results suggest a focus on previous low back disorders and previous sick leave for the design of early prevention programmes aiming at reducing future sick leave due to any cause, as well as due to NSBD, among nursing aides/assistant nurses. A multifactorial approach may be of importance in the early prevention of sick leave due to NSBD.Over the past century, sick leave, mainly attributed to musculoskeletal disorders (MSD), has increased in Sweden, especially among women [1]. In 2003, the proportion of women on sick leave was higher than in any previous year [1], indicating more individual suffering and also increased cost for the community. The prevalence of neck, shoulder and back pain is higher
Long-term particulate matter exposure and mortality: a review of European epidemiological studies
Claudio Pelucchi, Eva Negri, Silvano Gallus, Paolo Boffetta, Irene Tramacere, Carlo La Vecchia
BMC Public Health , 2009, DOI: 10.1186/1471-2458-9-453
Abstract: We searched the Medline database for epidemiological studies on air pollution and health outcomes published between January 2002 and December 2007. We also examined the reference lists of individual papers and reviews. Two independent reviewers classified the studies according to type of air pollutant, duration of exposure and health outcome considered. Among European investigations that examined long-term PM exposure we found 4 cohort studies (considering total and cardiopulmonary mortality), 1 case-control study (considering mortality from myocardial infarction), and 4 ecologic studies (2 studies considering total and cardiopulmonary mortality and 2 studies focused on cardiovascular mortality).Measurement indicators of PM exposure used in European studies, including PM10, PM2.5, total suspended particulate and black smoke, were heterogeneous. This notwithstanding, in all analytic studies total mortality was directly associated with long-term exposure to PM. The excesses in mortality were mainly due to cardiovascular and respiratory causes. Three out of 4 ecologic studies found significant direct associations between PM indexes and mortality.European studies on long-term exposure to PM indicate a direct association with mortality, particularly from cardiovascular and respiratory diseases.Data from European epidemiological studies on the relation between long-term exposure to particulate matter (PM) and mortality are still limited, as most research on health effects of air pollution has focused on short-term exposure [1]. Besides information on the issue from a few US cohort studies, including the American Cancer Society Cancer Prevention Study II (ACS-CPS) [2], the Harvard Six Cities Study [3], and the Women's Health Initiative Observational Study [4], a few European studies provided new data during the last 5 years.Ambient levels of several air pollutants are more variable within Europe than in the USA, and in some areas they are comparably high compared to US lev
Frontotemporal Dementia, Manifested as Schizophrenia, with Decreased Heterochromatin on Chromosome 1
Philippos Gourzis,Maria Skokou,Panagiotis Polychronopoulos,Evanthia Soubasi,Irene-Eva Triantaphyllidou,Christos Aravidis,Antonia-Ioanna Sarela,Zoe Kosmaidou
Case Reports in Psychiatry , 2012, DOI: 10.1155/2012/937518
Abstract: Introduction. Frontotemporal dementia is a disorder of complex etiology, with genetic components contributing to the disease. The aim of this report is to describe a young patient suffering from frontotemporal dementia, misdiagnosed as schizophrenia, related to a genetic defect on chromosome 1. Case Presentation. A 29-year-old female patient, previously diagnosed as having schizophrenia, was hospitalized with severe behavioural disturbances. She demonstrated severe sexual disinhibition, hyperphagia, lack of motivation, apathy, psychotic symptoms, suicidal thoughts, and cognitive deterioration. Focal atrophy of frontal and anterior temporal structures bilaterally was found on brain MRI, as well as bifrontal hypo perfusion of the brain on SPECT scan. The diagnosis of frontotemporal dementia was made clinically, according to Lund and Manchester groups and Neary diagnostic criteria. Chromosomal analysis was conducted and revealed decrease in length of heterochromatin on the long arm of chromosome 1 (46, XX, 1qh-). Parental karyotypes were normal. Discussion. Frontotemporal dementia, and particularly early-onset cases, can be often misdiagnosed as schizophrenia, with negative impact on case management. Genetic testing could be an aid to the correct diagnosis, which is crucial for optimal patient care.
The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis
Eva Jiménez-Medina, Enrique Berruguilla, Irene Romero, Ignacio Algarra, Antonia Collado, Federico Garrido, Angel Garcia-Lora
BMC Cancer , 2008, DOI: 10.1186/1471-2407-8-78
Abstract: The in vitro cytotoxic anti-tumour activity of PSK has been evaluated in various tumour cell lines derived from leukaemias, melanomas, fibrosarcomas and cervix, lung, pancreas and gastric cancers. Tumour cell proliferation in vitro was measured by BrdU incorporation and viable cell count. Effect of PSK on human peripheral blood lymphocyte (PBL) proliferation in vitro was also analyzed. Studies of cell cycle and apoptosis were performed in PSK-treated cells.PSK showed in vitro inhibition of tumour cell proliferation as measured by BrdU incorporation and viable cell count. The inhibition ranged from 22 to 84%. Inhibition mechanisms were identified as cell cycle arrest, with cell accumulation in G0/G1 phase and increase in apoptosis and caspase-3 expression. These results indicate that PSK has a direct cytotoxic activity in vitro, inhibiting tumour cell proliferation. In contrast, PSK shows a synergistic effect with IL-2 that increases PBL proliferation.These results indicate that PSK has cytotoxic activity in vitro on tumour cell lines. This new cytotoxic activity of PSK on tumour cells is independent of its previously described immunomodulatory activity on NK cells.A number of bioactive molecules, including antitumour substances, have been identified in various mushroom species. Polysaccharides are the best known and most potent of these and have antitumour and immunomodulating properties [1-5]. PSK, a protein-bound polysaccharide obtained from Basidiomycetes, also known as Krestin, has been used as an agent in the treatment of cancer in Asia for over 30 yrs [6-8]. PSK is derived from the fungus Coriolus versicolor and has documented anticancer activity in vitro in experimental models [9] and in human clinical trials. Several randomized clinical trials have demonstrated that PSK has great potential in adjuvant cancer therapy, with positive results in the treatment of gastric, esophageal, colorectal, breast and lung cancers [10,11]. These studies have suggested the ef
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