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Search Results: 1 - 10 of 26241 matches for " Eun Young Kim "
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Bus Stops and Bus Users in the City of Detroit
Eun-Young Kim
Solstice : Electronic Journal of Geography and Mathematics , 2002,
Abstract: The link to the fulltext on a current website is given below. Should that link fail to work, please go to this persistent URL and download the associated file for this issue. http://deepblue.lib.umich.edu/handle/2027.42/58219While you are there, take a look around and see if there are other issues and documents that are related to your interests!
Investigations on Structural Safety of Office Room Based on Fire Simulation and Transient Heat Transfer Analysis  [PDF]
Ah Young An, Eun Mi Ryu, Hee Sun Kim
World Journal of Engineering and Technology (WJET) , 2014, DOI: 10.4236/wjet.2014.23B004
Abstract:

This study aims at investigating heat propagations inside the structural members due to fire using fire simulation and transient heat transfer analysis. Toward that goal, fire simulation and transient heat transfer analysis for a 5-story building are carried out sequentially using Fire Dynamics Simulator (FDS) and ABAQUS 6.10-3, respectively. As results from fire simulation, temporal temperature information is obtained depending on various locations of the building, which is used as boundary condition for the structural elements generated in transient heat transfer analysis. Predictions from the transient heat transfer analysis show that the structural members are exposed spatially non-uniform temperatures which can cause significant eccentric deformation and aceleration of structural damages.


NS-398 induces caspase-dependent, mitochondria-mediated intrinsic apoptosis of hepatoma cells  [PDF]
Il Han Song, Suk Bae Kim, Hyun Duk Shin, Ha Yan Kang, Eun Young Kim
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.326084
Abstract: The present study was conducted to investigate whether mitochondrial pathway of apoptosis is involved in cyclooxygenase-2 (COX-2) inhibitor-induced growth inhibition of hepatoma cells. The growth rate and pattern of NS-398 (selective COX-2 inhibitor)-treated Hep3B hepatoma cells were analyzed by microscopic examination, DNA fragmentation gel analysis and flow cytometry followed by the cleavage of down-stream caspase 3 and the release of cytosolic fraction of cytochrome c assessed by Western blot analysis. NS-398 induced the growth inhibition of hepatoma cells depending on the concentration of this COX-2 inhibitor and time sequence. Ladder patterned-DNA fragmentation and cytometric redistribution to sub-G1 phase in cell cycle were revealed in NS-398-induced growth inhibition of hepatoma cells. Cytochrome c was translocated from mitochondria to cytosol in time-dependent manner following NS-398 treatment to hepatoma cells. COX-2 inhibitor induces the growth inhibition of hepatoma cells via caspase-dependent, mitochondria-mediated intrinsic apoptosis pathway. These results strongly suggest the possibility of therapeutic implication of COX-2 inhibitor in HCC.
The Effects of Sleep Deprivation on the Biophysical Properties of Facial Skin  [PDF]
Min Ah Kim, Eun Joo Kim, Byung Young Kang, Hae Kwang Lee
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2017, DOI: 10.4236/jcdsa.2017.71004
Abstract: Lack of sleep is a problem in today’s society, and many people are concerned about changes in their outward appearance due to lack of sleep. People generally come up with some noticeable skin attributes as symptoms of sleep deficiency including rough, dull, and dry skin as well as droopy eyelids and dark eye circles. Several previous reports also suggested that poor sleep could affect the skin condition. The purpose of this study was to evaluate the effect of one night of sleep deprivation on various skin biophysical properties. Twenty four healthy females participated in a study of one night of sleep deprivation. Subjects were kept awake for one night in a laboratory with controlled temperature and relative humidity. The skin condition of each subject was evaluated after normal sleep pattern and after one night of sleep deprivation. The measured skin biophysical parameters included transepidermal water loss, facial pore size, and skin tone, hydration, elasticity, desquamation, translucency, and blood flow. The cheek, eye, and lip areas were evaluated. After one night of sleep deprivation, multiple skin biophysical parameters showed changes when compared to the baseline measurements. A significant decrease in skin hydration and impaired barrier function were observed (p < 0.05). Decreased hydration led to decreased skin elasticity and translucency and increased skin scaling (p < 0.05). Facial pores were more conspicuous, and skin lightness decreased significantly (p < 0.05). Furthermore, skin blood flow decreased prominently (p < 0.05). The results demonstrated that the skin features that are recognized as symptoms of sleep deficiency actually showed remarkable differences after a period of sleep deprivation, and some of these features were confirmed in the eye, lip, as well as the cheek areas. This study revealed a significant association between sleep deprivation and skin biophysical properties by scientific measuring.
Effects of the Boron-Doped p+ Emitter on the Efficiency of the n-Type Silicon Solar Cell
Eun-Young Kim,Jeong Kim
Advances in Materials Science and Engineering , 2013, DOI: 10.1155/2013/974507
Abstract: The optimum structure of the p+ emitter for the n-type silicon solar cell was determined with the simulation of the boron doping concentration. The boron concentration ( ) in the p+ emitter was varied in the range of and ?atoms/cm3 while maintaining the base doping concentration at ?atoms/cm3. With the increase of the boron concentration, the open circuit voltage ( ) of the cell increased up to 0.525?V and then was nearly saturated at ?atoms/cm3. On the other hand, the short circuit current density ( ) began to decrease at ?atoms/cm3 due to the increase of the surface recombination loss, and without considering the variation of the contact resistance along the emitter doping level, the maximum efficiency of the cell was obtained at around ?atoms/cm3. While the contact resistance of the electrode decreases with the increase of the doping concentration in the p+ emitter, and with consideration of the variation of the contact resistance, the optimum value of for maximum efficiency shifted to the higher doping level. 1. Introduction Currently, the p-type silicon solar cell comprises a large portion of the industrial solar cells. On the other hand, the n-type silicon solar cell has been known to have many advantages and has subsequently received a great deal of attention and has become one of the main development topics in PV industries. Crystalline silicon solar cell using the n-type wafer showed the highest efficiency record among commercial silicon solar cells [1]. The n-type wafer has a longer diffusion length than the p-type wafer as a result of a higher tolerance to common transition metal impurities [2, 3]. Also, it does not contain any boron-oxide pairs, which are considered as the origin of light-induced degradation (LID) in the p-type Si wafer [4]. Thus, the performance of the n-type silicon solar cell can almost be maintained without degradation during the illumination of light. Furthermore, since the doping profile of boron is more similar to the theoretical model than that of phosphorous, the application of simulation to the real emitter diffusion process is more suitable for the n-type Si wafer. In spite of the definite advantages of n-type silicon, p-type silicon comprises 85% of industrial silicon solar cells. Historically, research and process infrastructure have been mainly developed for p-type silicon solar cells, which are essential to make economical and high-efficient commercial solar cells. In order to realize a p+ emitter on n-type silicon wafer, three kinds of methods are usually applied: (i) boron-diffused emitter, (ii) Al-alloyed
Rolling Fatigue Test of Large-Sized UHPC Member for Cable Stayed Bridge  [PDF]
Jeong-Rae Cho, Young Jin Kim, Jong Sup Park, Eun Suk Choi, Won Jong Chin
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.410082
Abstract: Recently, research strives to apply Ultra High Performance Concrete (UHPC) to large-sized structures owing to its remarkable mechanical performance and durability compared to normal concrete. The Korea Institute of Construction Technology proposed SuperBridge800, an edge girder type UHPC cable stayed bridge with central span of 800 m, through its detailed design. The bridge is designed to be erected through the connection of precast UHPC segments. The precast UHPC segment is monolithically composed of one ribbed deck slab and edge girders at each side. The connection between the precast segments is achieved by steel bars at the edge girders and by UHPC cast-in-place wet joint at the slab. Despite of the outstanding mechanical performance of UHPC, the fabrication of large-sized members is a difficult task since UHPC hardens faster than normal concrete and requires a special curing process. Therefore, the constructability of large-sized UHPC segment should be secured to achieve SuperBridge800. Besides, the performance of the connection between segments should also be guaranteed, especially in terms of the fatigue performance of the UHPC cast-in-place joint, which constitutes a weak point. To that goal, two half-scaled UHPC segments are manufactured and the constructability is examined by fabricating a large-sized UHPC member connected with respect to the design conditions. This study conducts rolling fatigue test on the so-fabricated large-sized UHPC member. Rolling fatigue test is carried out up to 2 million cycles considering actual vehicle load at each center and quarter points of the member. The test results confirm that the service limit state is satisfied.
A Case of Secondary Iris Cyst AfterPupilloplasty*  [PDF]
Ja Young Lee, Sun Woong Kim, Eun Suk Koh, Jee Ho Chang
Open Journal of Ophthalmology (OJOph) , 2013, DOI: 10.4236/ojoph.2013.31004
Abstract:

Purpose: To investigate the pathogenesis of a secondary iris cyst with an immunohistochemical method. Methods: Single observational case report. A pathologic specimen was obtained from a 5-year-old girl who was found to have a secondary iris cyst. She had a history of previous penetrating ocular trauma and subsequent cataract surgery and pupilloplasty. Immunohistochemical staining with cytokeratin (CK) 19 and CK3 was used. Results: After immunohistochemical staining, the inner wall showed positive staining for CK19, which is specific for limbal, peripheral cornea and conjunctival epithelium, and negative staining for CK3, which is specific for corneal epithelium. Conclusions: With the aid of immunohistochemical analysis, a conjunctival epithelial origin was indicated, and pupilloplasty was identified as the causal event of the iris cyst while the possibility of primary iris cyst was ruled out.

Robust multi-site MR data processing: iterative optimization of bias correction, tissue classification, and registration
Eun Young Kim,Hans J. Johnson
Frontiers in Neuroinformatics , 2013, DOI: 10.3389/fninf.2013.00029
Abstract: A robust multi-modal tool, for automated registration, bias correction, and tissue classification, has been implemented for large-scale heterogeneous multi-site longitudinal MR data analysis. This work focused on improving the an iterative optimization framework between bias-correction, registration, and tissue classification inspired from previous work. The primary contributions are robustness improvements from incorporation of following four elements: (1) utilize multi-modal and repeated scans, (2) incorporate high-deformable registration, (3) use extended set of tissue definitions, and (4) use of multi-modal aware intensity-context priors. The benefits of these enhancements were investigated by a series of experiments with both simulated brain data set (BrainWeb) and by applying to highly-heterogeneous data from a 32 site imaging study with quality assessments through the expert visual inspection. The implementation of this tool is tailored for, but not limited to, large-scale data processing with great data variation with a flexible interface. In this paper, we describe enhancements to a joint registration, bias correction, and the tissue classification, that improve the generalizability and robustness for processing multi-modal longitudinal MR scans collected at multi-sites. The tool was evaluated by using both simulated and simulated and human subject MRI images. With these enhancements, the results showed improved robustness for large-scale heterogeneous MRI processing.
Evaluation of Antioxidant and Anti-Inflammatory Effect of Rhododendron brachycarpum Extract Used in Skin Care Product by in Vitro and in Vivo Test  [PDF]
Amal Kumar Ghimeray, Ha Youn Lee, Young Hoon Kim, Eun Kyung Ryu, Moon Sik Chang
Technology and Investment (TI) , 2015, DOI: 10.4236/ti.2015.62011
Abstract: In this study, we aimed to observe the cytotoxicity, antioxidant and anti-inflammatory activity of Rhododendron brachycarpum extract (RbE) in RAW 264.7 macrophage cell in vitro and the anti-inflammatory or soothing effect of RbE formulated cream (Multicalm-RHTM) on experimentally induced acute irritated skin in healthy subjects in vivo. In vitro study revealed that RbE significantly inhibited NO and ROS generation in a dose dependent manner without cytotoxicity. In clinical test, Multicalm-RHTM cream siginificantly reduced the SLS-enduced erythema after D5 compared to that of placebo. Overall, it can be concluded that the RbE is a non-cytotoxic, antioxidant and anti-irritant agent which can be used as a potent functional ingredient in cosmetics. Likewise, the in vivo clinical study shows that Multicalm-RHTM cream which contains 3% RbE can be used as an effective skin soothing agent.
Dual PINK Mutant and Aβ42-Dependent Lifespan Shorten and Flight Impairment in Transgenic Drosophila Partially Alleviates by a Lactococcus lactis Supplemented Diet  [PDF]
Dong Gyun Ko, Young Bum Eun, Jong Uk Na, Sang-Tae Kim
Journal of Behavioral and Brain Science (JBBS) , 2015, DOI: 10.4236/jbbs.2015.57027
Abstract: Oxidative stress has been strongly related with Parkinson disease (PD) and Alzheimer disease pathogenesis. We determined the effects of Lactococcus lactis (LAL) supplementation on the generated loss-of-function mutants of PINK1 B9, an AR-JP-linked gene and Aβ42 induced phenotypes in a Drosophila melanogaster model of PD/AD. Enhanced mutant PINK1 B9 and Aβ42 expression in D. melanogaster dopaminergic (DA) neurons can curtail lifespan, flight muscle accompanied by locomotive defects and we have observed longevity methods to assay the effects of LAL on D. melanogaster survival. Furthermore, flies expressing mutant PINK1 B9 and Aβ42 in their brain fed LAL had up to the two weeks, or 25%, greater median lifespan than those fed a standard sucrose diet. In addition, LAL improved mutant PINK1 B9 and Aβ42-induced flight impairments in the Drosophila wing. Our microscopy analyses revealed that individuals fed LAL had improved atypical ommatidia as well as an increased thirteen percentage of flight ability than those fed a control diet. We propose that LAL, rich in naturally occurring probiotics and antioxidants, promotes the survival of neurons in brain and wing muscle tissues with increased levels of mutant PINK1 B9 and Aβ42 via a protective cell survival mechanism.
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