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Search Results: 1 - 10 of 223958 matches for " Estella; Cartier R "
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Leucemia linfoma T del adulto en Chile.: Estudio clínico-patológico y molecular de 26 pacientes
Cabrera C,M Elena; Labra G,Silvia; Meneses C,Pedro; Matutes,Estella; Cartier R,Luis; M Ford,Anthony; F Greaves,Melvyn;
Revista médica de Chile , 1999, DOI: 10.4067/S0034-98871999000800007
Abstract: background: adult t cell leukemia lymphoma is a lymphoproliferative syndrome etiologically associated to human t cell lymphotropic virus type i. aim: to describe the clinical and laboratory features of 26 caucasian chilean patients, with htlv-i positive adult t-cell leukemia lymphoma (atll). material and methods: diagnostic criteria included clinical features, cell morphology, immunophenotype, htlv-i serology and/or dna analysis by southern blot or pcr. results: according to the clinical presentation, 12 cases had the acute atll form, 6 had a lymphoma, 4 the chronic form and 4 had smoldering atll. the median presentation age was 50 years, younger than the japanese patients, but significantly older than patients from other south american countries (eg brasil, jamaica, colombia). the main clinical features: lymphadenopathy, skin lesions and hepatosplenomegaly, were similar in frequency to those of patients from other countries, except for the high incidence of associated neurological disease. tropical spastic paraparesis (tsp) in our series of atll, was seen in one third of the patients (8/26). a t-cell immunophenotype was shown in all 26 cases and htlv-i serology was positive in 25/26 patients. molecular analysis on the seronegative patient showed clonal integration of proviral htlv-i dna into the lymphocytes dna, and thus he may have been a poor responder to the retroviral infection. proviral dna integration was also demonstrated in 15/16 patients being clonal in 10, polyclonal in 3 (all smoldering cases) and oligoclonal in one. conclusions: atll in chile has similar clinical and laboratory features than the disease in other parts of the world, except for a younger age than japanese patients but older than those from other latin american countries and a high incidence of patients with associated tsp. detailed morphological and immunophenotypic analysis of the abnormal circulating lymphocytes, together with the documentation of htlv-i by serology and/or dna analysis
Paraparesia espástica progresiva asociada a HTLV-I en Chile: Estudio y seguimiento de 121 pacientes por diez a?os
Cartier R,Luis;
Revista chilena de neuro-psiquiatría , 2009, DOI: 10.4067/S0717-92272009000100007
Abstract: revision is made to 121 chilean patients with progressive adult spastic paraparesis (psps) associated to htlv-i. epidemiologic, clinical, diagnosis and associated illnesses aspects are analyzed as well as the pathogenesis. the follow-up of patients during several years allowed defining the evolutional profile, establishing the causes of death and studying the virus' behavior. pathogenesis hypothesis arose from the neuropathological search to define the mechanisms of damage supported on immunohystochemical studies. it was confirmed that the cns illness is a degenerative process linked to a central axonopathy which expresses flaws in the axoplasmic transport, particularly affecting the corticospinal tracts, although there is a more extended myeloencephalic involvement. furthermore, the virus is capable of producing a multisystemic illness that may simultaneously involve the nervous system; the hematological system; the exocrine glands; the hepatic, lung, muscular and bone parenchymas.
Caídas y alteraciones de la marcha en los adultos mayores
Cartier R.,Luis;
Revista médica de Chile , 2002, DOI: 10.4067/S0034-98872002000300014
Abstract: there is a higher frequency of falls in the elderly than in young people, due to age related physiological changes in gait. there is a lower amplitude of pelvic movements that affects gait efficiency. equilibrium is also disturbed since the trunk assumes the leadership of gait, displacing the pelvis. many diseases of elderly individuals, such as parkinson disease, spastic paraparesis, cerebrovascular accidents or neuropathies, further impair the gait. therefore, after the age of 65, all falls must be considered symptomatic (rev méd chile 2002; 130: 332-7)
Tratado de Neuropsicología
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2008,
Abstract:
La importancia social de la neurociencia The social consequence of neuroscience
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2010,
Abstract:
Sesenta y cinco a os de existencia Sixty five years' existence
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2011,
Abstract:
Paraparesia espástica progresiva asociada a HTLV-I en Chile: Estudio y seguimiento de 121 pacientes por diez a os Progresive spastic paraparesis associated to HTLV-I in Chile
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2009,
Abstract: Se revisan las paraparesias espásticas progresivas del adulto (PEPAs) producidas por el HTLV-I, en 121 pacientes chilenos. Se analizan los aspectos epidemiológicos, clínicos, diagnósticos, las enfermedades asociadas, y la patogenia. El seguimiento de los pacientes durante varios a os permitió definir el perfil evolutivo, establecer las causas de muerte y estudiar el comportamiento del virus. De los casos con anatomía patológica surgieron hipótesis, que han permitido definir mecanismos de da o, sustentados en estudios inmunohistoquímicos. Se pudo confirmar que la enfermedad del SNC es un proceso degenerativo, vinculado a una axonopatía central que expresa fallas del transporte axoplásmico, que afecta particularmente la vía corticoespinal, aunque existe un compromiso más extenso mielo-encefálico. Además, el virus es capaz de producir una enfermedad multisistémica, que puede comprometer simultáneamente el sistema nervioso, el sistema hematológico, las glándulas exocrinas, el parénquima hepático, pulmonar, muscular y óseo. Revision is made to 121 Chilean patients with progressive adult spastic paraparesis (PSPs) associated to HTLV-I. Epidemiologic, clinical, diagnosis and associated illnesses aspects are analyzed as well as the pathogenesis. The follow-up of patients during several years allowed defining the evolutional profile, establishing the causes of death and studying the virus' behavior. Pathogenesis hypothesis arose from the neuropathological search to define the mechanisms of damage supported on immunohystochemical studies. It was confirmed that the CNS illness is a degenerative process linked to a central axonopathy which expresses flaws in the axoplasmic transport, particularly affecting the corticospinal tracts, although there is a more extended myeloencephalic involvement. Furthermore, the virus is capable of producing a multisystemic illness that may simultaneously involve the nervous system; the hematological system; the exocrine glands; the hepatic, lung, muscular and bone parenchymas.
La Sociedad de Neurología, Psiquiatría y Neurocirugía que nos legaron The Neurology, Psychiatry and Neurosurgery Society legacy we have inherited
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2009,
Abstract:
Abril: mes del cerebro April: brain awareness month
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2012,
Abstract:
El HTLV-I Un virus que preocupa HTLV-I a virus of concern
Luis Cartier R
Revista Chilena de Neuro-Psiquiatría , 2009,
Abstract:
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