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Search Results: 1 - 10 of 139592 matches for " Ernest ?turdík "
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Martina Danihelová,Ernestturdík
Potravinarstvo : Scientific Journal for Food Industry , 2012, DOI: 10.5219/206
Abstract: Buckwheat represents a raw material interesting in term of its nutritional and health beneficial suitability. Buckwheat grain is a source of valuable proteins, starch with low glycemic index or high amount of unsaturated fatty acids. It contains compounds with prophylactic value, too. Buckwheat is one of the richest sources of flavonoids. The highest content of dietary fibre is in bran fraction, where it counts for 40 %. Present phytosterols are usefull in lowering blood cholesterol. Buckwheat is better source of magnesium, potassium, phosphorus, zinc, manganese and copper than other cereals. Among vitamins the most abundant is pyridoxin. Buckwheat is effective in management of many diseases, mainly cardiovascular and digestion disorders, cancer, diabetes and obesity. In the last decades buckwheat is an interesting material not only for development of new functional foods, but for the preparation of concentrates with healing buckwheat components, too. doi:10.5219/206
Antioxidant and antiproteinase effects of buckwheat hull extracts
Martina Danihelová,Ernestturdík
Potravinarstvo : Scientific Journal for Food Industry , 2013, DOI: 10.5219/272
Abstract: Buckwheat is known not only due to its appropriate nutritional composition but the content of prophylactic compounds, too. These are responsible for buckwheat beneficial impact on human health. Most of them are concentrated in outer layers of buckwheat grain. The subject of this work was to screen hulls of nine common and one tartary buckwheat cultivar for the content of flavonoids and its antioxidant and antiproteinase effects. The highest content of total flavonoids was determined for tartary buckwheat cultivar Madawaska (0.6% of hulls weight). Among common buckwheat cultivars the best values reached samples Bamby (0.23%) and KASHO-2 (0.11%). Antioxidant activity as detected via binding radical ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) and monitoring reducing power was the most effective for samples with highest flavonoid content. Buckwheat hulls effectively inhibited pathophysiological proteases thrombin and urokinase, whereas only little effects were seen to trypsin and elastase. In this testing there were again the best samples with highest flavonoid content. Only tartary buckwheat Madawaska effectively inhibited elastase at tested concentrations. No significant correlation was determined between flavonoid content and measured antioxidant or protease inhibitory action. Obtained results allow us to commend tartary buckwheat cultivar Madawaska as well as common buckwheat cultivars Bamby and KASHO-2 for further experiments. doi:10.5219/272
Martina Danihelová,Ernestturdík
Potravinarstvo : Scientific Journal for Food Industry , 2011, DOI: 10.5219/160
Abstract: Flavonoids as natural bioactive compounds are present in almost every sort of fruits, vegetables and from them derived products. Flavonols may be found mainly in fruits and vegetables, while flavones are abundant in herbs and spices. Rich natural sources of flavanols are tea, cocoa, grape seeds or apple skin. Flavanones are primarily found in a variety of citrus fruits and anthocyanidins in many coloured berries. Soy is rich in isoflavonoids. Average daily intake of flavonoids is approximately in the range of 150 to 300 mg. It strongly depends on individual, country and culture usages. In west countries main dietary sources of flavonoids consist of tea, wine and fruits, while in east countries there is consumed mainly soy with high isoflavonoid content. Many studies have shown, that intake of fruits and vegetables with high flavonoid content is associated with lowered risk of incidence of some diseases such as cardiovascular or cancer. These findings are attributed to experimentally confirmed biological effects of flavonoids - antioxidant, anti-inflammatory, anti-allergic, anticancer or cardioprotective. The final effect is however depending on their bioavailability, which is in the case of flavonoids not high, because in the nature dominating flavonoid glycosides can poorly penetrate through lipophilic cell membranes. Final effective molecules are flavonoid metabolites, that more or less retain their biological activities. doi: 10.5219/160
Lenka Duchoňová,Ernestturdík
Potravinarstvo : Scientific Journal for Food Industry , 2010, DOI: 10.5219/76
Abstract: Still more alarming obesity studies show in fact that it is largely due to incorrect diet and lifestyle. For suitable alternative for prevention of this disease are now considered cereal foods, mainly based on increased fiber content. The importance of dietary fiber for human organism consist primarily in its protective function before civilization diseases. It has beneficial effects on digestive physiology and it is therefore an important factor in the prevention of obesity, but also other diseases. Fiber consumption in developed countries is low and it is below the lower limit of the recommended dose. Slovaks per day take only 10-12 g of fiber, which represents only 47% of the recommended dose. Recent large-scale epidemiological studies have shown that regular consumption of wholegrain cereals can reduce the risk of heart disease and certain cancers by 30 percent. One of the factors that increase the functionality of foods is the so-called indigestible resistant starch. For its the positive impact on the physiology of digestion is referred to as prebiotics new generation of dietary fiber. The increasing availability of tasty, whole grain products rich in fiber could be health benefits.
Lipophilization of flavonoids for their food, therapeutic and cosmetic applications
Martina Danihelová , Jana Viskupi ová , , Ernest turdík
Acta Chimica Slovaca , 2012, DOI: 10.2478/v10188-012-0010-6
Abstract: Flavonoids represent large group of plant pigments. These polyphenolic compounds may be found in the nature as active components of fruits, vegetables and other plants and derived products. Due to established biological effects they are attractive substances for many areas of human life. Many flavonoids are nowadays used in pharmaceutical, cosmetic and food preparations. Their practical applications are in most cases limited by low solubility and stability in lipophilic media. Chemical or enzymatic lipophilization of flavonoid skeleton may not only increase their solubility and stability in lipophilic environment but also their biological properties. This review summarizes current knowledge in this field.
Hop pellets as an interesting source of antioxidant active compounds
Andrea Holubková,Silvia Mo?ovská,Barbora Baloghová,Ernestturdík
Potravinarstvo : Scientific Journal for Food Industry , 2013, DOI: 10.5219/270
Abstract: Hop is a plant used by humankind for thousands of years. This plant is one of the main and indispensable raw materials for the beer production. It is used for various dishes preparation in the cuisine. Hop is also used to inhibit bacterial contamination. The hop extracts are used for its sedative, antiseptic and antioxidant properties in medicine, as a part of many phytopharmaceuticals. The present paper have focused on the extraction of polyphenolic compounds from 4 samples of hop pellets varieties of Aurora, Saaz, Lublin and Saphir, on the analyzing of bioactive substances (polyphenolics and flavonoids) in prepared extracts and on the determination of antioxidant activity. The highest content of polyphenolic substances was determined in the sample Lublin (153.06 mg gallic acid (GAE)/g) and Saaz (151.87 mg GAE/g). The amount of flavonoids in the samples was descending order Saaz > Saphir > Aurora > Lublin. Hops, as plant, is known by high content of antioxidant active substances. Antioxidant activity was determined using three independent spectrofotometric methods, radical scavenging assays using 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and ferric reducing antioxidant power (FRAP). The sample Aurora showed the highest ability to scavenge of ABTS radical cation. Antioxidant activity continued to decline in a r
Risk Factors, Clinical Features, Baseline Alanine Aminotransferase and CD4+ Count of Children with HIV Co-Infection with Hepatitis B and C at a Tertiary Hospital in Southwest Nigeria  [PDF]
M. O. Durowaye, S. K. Ernest, I. A. Ojuawo
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.74030
Abstract: Background: Human immunodeficiency virus and hepatitis B and C viruses are endemic in sub- Saharan African countries including Nigeria. Researchers have studied the burden of co-infection of HIV with hepatitis B and hepatitis C but the risk factors and clinical presentation have not been much addressed especially in children. Methodology: This was a prospective cross sectional study that determined the prevalence, risk factors, clinical features, baseline CD4+ count, CD4+ percentage, and alanine aminotransferase (ALT) of newly diagnosed, HAART na?ve HIV co-infection among children who were managed at a Tertiary Hospital in Ilorin, Nigeria. Result: Of the 60 HIV- infected children recruited, 11.7% had HIV co-infection with HBV or HCV. Children with co-infec- tions (mean age 8.43 ± 2.37 years) were significantly older than their HIV mono-infected counterparts (mean age 5.25 ± 3.96 years) (p = 0.011). There was no significant difference between HIV monoinfection and HIV co-infection with respect to gender (p = 0.758), ethnicity (p = 0.707), religion of parents (p = 0.436), family type (p = 0.184), social class (p = 0.535), previous transfusion (p = 0.053), scarification (p = 0.612), female genital mutilation (p = 0.778), and sharing of clippers (p = 0.806). The mean BMI, immunological staging (p = 0.535), baseline ALT (p = 0.940), and mean baseline CD4+ count (p = 0.928) were comparable. However, the body mass index of HIV co-infec- ted children decreased with age up till age 10 years. Conclusion: There were no risk factors, nor clinical features predictive of co-infection identified in this study. Co-infection did not negatively impact baseline, CD4+ count and ALT.
Singlet fermion dark matter and electroweak baryogenesis with radiative neutrino mass
Babu, K. S.;Ma, Ernest
High Energy Physics - Phenomenology , 2007, DOI: 10.1142/S0217751X08040299
Abstract: The model of radiative neutrino mass with dark matter proposed by one of us is extended to include a real singlet scalar field. There are then two important new consequences. One is the realistic possibility of having the lightest neutral singlet fermion (instead of the lightest neutral component of the dark scalar doublet) as the dark matter of the Universe. The other is a modification of the effective Higgs potential of the Standard Model, consistent with electroweak baryogenesis.
Foetal Radiation Dose and Risk from Diagnostic Radiology Procedures: A Multinational Study
Ernest K. Osei,Johnson Darko
ISRN Radiology , 2013, DOI: 10.5402/2013/318425
Abstract: In diagnostic radiology examinations there is a benefit that the patient derives from the resulting diagnosis. Given that so many examinations are performed each year, it is inevitable that there will be occasions when an examination(s) may be inadvertently performed on pregnant patients or occasionally it may become clinically necessary to perform an examination(s) on a pregnant patient. In all these circumstances it is necessary to request an estimation of the foetal dose and risk. We initiated a study to investigate fetal doses from different countries. Exposure techniques on 367 foetuses from 414 examinations were collected and investigated. The FetDoseV4 program was used for all dose and risk estimations. The radiation doses received by the 367 foetuses ranges: <0.001–21.9?mGy depending on examination and technique. The associated probability of induced hereditary effect ranges: <1 in 200000000 ( ) to 1 in 10000 ( ) and the risk of childhood cancer ranges <1 in 12500000 ( ) to 1 in 500 ( ). The data indicates that foetal doses from properly conducted diagnostic radiology examinations will not result in any deterministic effect and a negligible risk of causing radiation induced hereditary effect in the descendants of the unborn child. 1. Introduction In diagnostic radiology examinations, there is a benefit that the patient derives from the resulting diagnosis, provided that they are fully justified. However, given that so many examinations are performed each year, it is inevitable that there will be occasions when an examination will be performed on a woman who subsequently discovers that she was pregnant at the time of her examination(s). It may also occasionally become clinically necessary to perform a radiological examination(s) on a woman who is known to be pregnant. In the later case, there must be rigorous justification of the examination and the procedure itself must be optimized to minimise the foetal dose [1–3]. In order to avoid the former, some special rules have been developed to apply to the exposure of potentially pregnant women (who are or who may be pregnant) in which radiological examinations of such women are restricted to a certain period following menstruation [4–7]. For the protection of the foetus from occupational exposure of the pregnant worker, the International Commission on Radiological Protection (ICRP) [1, 2] considers that if a female worker has declared (i.e., notified her employer) that she is pregnant, additional controls have to be considered to protect the embryo/foetus. It is the Commission’s policy that the
A Survey of Organ Equivalent and Effective Doses from Diagnostic Radiology Procedures
Ernest K. Osei,Johnson Darko
ISRN Radiology , 2013, DOI: 10.5402/2013/204346
Abstract: The quantification of radiation risks associated with radiological examinations has been a subject of interest with the increased use of X-rays. Effective dose, which is a risk-weighted measure of radiation to organs in the body associated with radiological examination, is considered a good indicator of radiological risk. We have therefore investigated patient effective doses from radiological examinations. Organ and effective doses were estimated for 94 patients who underwent computed tomography examinations and for 338 patients who had conventional radiography examinations. The OrgDose (version 2) program was used for the estimation of effective doses. The tube potential ranges: 57?kVp to 138?kVp depending on the examination and patient size. The entrance surface doses have a wide range even for the same examination: 0.44–10.31?mGy (abdomen) and 0.66–16.08?mGy (lumbar spine) and the corresponding effective dose ranges 0.025–0.77?mSv and 0.025–0.95?mSv respectively. Effective dose for adult abdomen-pelvic CT examinations ranges 5.4–19.8?mSv with a mean of 13.6?mSv and for pediatrics ranges 2.1–5.5?mSv with a mean of 2.7?mSv. The mean effective dose for adult chest and head CT examinations are 7.9 and 1.8?mSv respectively and for pediatrics are 1.7 and 1.1?mSv. 1. Introduction Diagnostic radiology imaging techniques including conventional radiography, fluoroscopy, and computed tomography (CT) procedures will continue to provide tremendous benefits to modern healthcare and the benefit derived by the patient will far outweigh the small risk associated with any properly conducted imaging modality. Nonetheless, it is important to be able to quantify the risks associated with radiological examinations of patients [1–11]. Access to such information will allow physicians and their patients to better weigh the risks of radiation exposure against the benefits afforded by various radiological examinations and hence make the best informed decisions in terms of options for other diagnostic modalities. The increase in patients undergoing radiological examinations (especially in CT) has created a great deal of interest in quantifying the risk associated with radiological examinations. Effective dose which is a risk-weighted measure of radiation to organs in the body associated with an examination(s) is considered a good indicator of radiological risk [2–6]. However, it should be realized that effective dose represents a generic estimate of risk from a given procedure for a generic model of the human body [11]. Estimated effective dose from a particular examination
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