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Search Results: 1 - 10 of 139 matches for " Eray Eroglu "
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Modification of Moufarrege Total Posterior Pedicle Mammaplasty: Conical Plicated Central U Shaped (COPCU's) Mammaplasty  [PDF]
Eray Copcu
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.22018
Abstract: Reduction mammaplasty and mastopexy is one of the biggest operation groups which have many techniques and their modifications. Generally accepted that, new modifications are the results of improvements of existing techniques. In this study we present a new modification of Moufarrege total posterior pedicle mammaplasty. We performed central plication to achieve a juvenile look in the superior pole of the breast and to prevent postoperative pseudoptosis and used central U shaped flap to achieve maximum NAC safety and to preserve lactation and nipple sensation. Sixty-nine patients were operated with the above mentioned tech-nique. Out of 69 patients, 52 underwent reduction mammaplasty (11 had gigantomastia), eleven mastopexy, and six oncoplastic. All of the patients were satisfied with functional and aesthetic results and none of them had major complications such as total NAC loss. Only six patients had wound healing problems on the suture line and two patients had minimal hematoma. Since we performed conical plication we would like to evalu-ate long term effects of the plication in the breast parenchyma. Breast parenchyma was visualized with USG in younger patients and mammography in older patient in postoperative 6 months and 1 year. We never observed any problem related with our sutures and retroareolar part of the areola examination for ductal patency was performed and interestingly all the patients had very clear ductal patency. Our modification is a safe, reliable technique which creates the least scar, avoids previously described disadvantages, provides maximum preservation of functions, can be employed in all breasts regardless of their sizes and is appropriate for oncoplastic surgery and revision surgery.
Coming from behind to win - A Qualitative research about psychological conditions of adolescents who have undergone open-heart surgery for single ventricle between the ages 0-5
Oguzhan Zahmacioglu, Cenk Eray Yildiz, Bulent Koca, Murat Ugurlucan, Selman Gokalp, Gurkan Cetin, Ayse Guler Eroglu, Funda Oztunc
Journal of Cardiothoracic Surgery , 2011, DOI: 10.1186/1749-8090-6-155
Abstract: Apprehensions of the parents when their children have health problems of vital importance have been widely witnessed. The natural unpredictability harbored by the possibility of losing a child is one of the most difficult trials encountered by the human mind. Some children and parents overcome this tribulation by the help of physicians, but some cannot. Early recognition of complex cardiac pathologies and their correction at birth or at infancy is therefore of vital importance. Life goes on for the lucky children who have undergone a successful surgery and the parents who have suffered profound anxiety throughout the entire process. On account of the developments in cardiac surgery, surveillance of the children with congenital cardiac defects has widened considerably enabling 85% of the cases to reach adolescence and adulthood [1]. Thus, the population of adolescents and young adults who have had open heart surgery at a very early age is increasing [2]. However, another process takes start in the lives of these individuals who have undergone surgery, such as periodic follow-ups and occasions of facing complications like arrhythmias, pulmonary hypertension, hematological problems and cardiac failure [3]. The questions are how good the quality of life will be for these patients, what the qualitative effects of difficult experiences in early life will be in young adulthood, and what the extent of the psychological effects of the illness are. There are studies on the lives of adolescents and young adults who were born with congenital heart disorders. Some are designed to assess academic performance by means of tests and questionnaires and some investigate quality of life, anxiety status, depression and conformity [4-7], and have been useful in revealing the psychological problems experienced. There are relatively much less data on those who have had successful corrective surgery at a very early age and are able to survive without suffering major health problems. Reports
Unusual Clinical Presentation of Ethylene Glycol Poisoning: Unilateral Facial Nerve Paralysis
Eray Eroglu,Ismail Kocyigit,Sami Bahcebasi,Aydin Unal,Murat Hayri Sipahioglu,Merva Kocyigit,Bulent Tokgoz,Oktay Oymak
Case Reports in Medicine , 2013, DOI: 10.1155/2013/460250
Abstract: Ethylene glycol (EG) may be consumed accidentally or intentionally, usually in the form of antifreeze products or as an ethanol substitute. EG is metabolized to toxic metabolites. These metabolites cause metabolic acidosis with increased anion gap, renal failure, oxaluria, damage to the central nervous system and cranial nerves, and cardiovascular instability. Early initiation of treatment can reduce the mortality and morbidity but different clinical presentations can cause delayed diagnosis and poor prognosis. Herein, we report a case with the atypical presentation of facial paralysis, hematuria, and kidney failure due to EG poisoning which progressed to end stage renal failure and permanent right peripheral facial nerve palsy. 1. Introduction Ethylene glycol (EG) may be consumed accidentally or intentionally, usually in the form of antifreeze products or as an ethanol substitute. It is converted by alcohol dehydrogenase to active metabolites in the liver, and these metabolites cause metabolic acidosis with increased anion gap, renal failure, hypocalcemia, oxaluria, and damage to the central nervous system and cranial nerves [1–3]. Diagnosis of EG poisoning could be a challenge due to altered mental status and lack of poisoning history. While metabolic acidosis with increased anion gap is common, osmolar gap resolves within 24 to 72 hours as the EG is metabolized to toxic metabolites. Early initiation of treatment can reduce the mortality, and morbidity but different presentations especially with delayed cases could be a problem, so patients with acute renal failure require more attention [4]. In cases of renal failure with the suspicion of EG poisoning, kidney biopsy should be considered promptly. Histological examination of renal tissue often reveals widespread necrosis of the tubular epithelium and deposition of a multitude of doubly refractile oxalate crystals in the distal tubules and collecting ducts [5, 6]. Herein, we report a case with the atypical presentation of facial paralysis, hematuria, and kidney failure due to EG poisoning. 2. Case Report A 25-year-old man was admitted to the emergency department of our university hospital with sudden onset of nausea, vomiting, slight mental disability, and abdominal pain. Cardiovascular, respiration, and gastrointestinal system examination findings were normal. The neurological examinations of the cranial nerves and limbs were normal. He was clinically dehydrated. On the first day of his admission, laboratory studies revealed a BUN level of 35?mg/dL, creatinine level of 3.17?mg/dL, calcium level of
General Purpose Wireless Communication System Using Data Acquisition  [PDF]
Abdullah Eroglu, Bill Westrick
Communications and Network (CN) , 2012, DOI: 10.4236/cn.2012.41007
Abstract: A sensor-enabled and RFID-integrated, Wireless Data Acquisition System (WDAS) that has similar functionality as multiple input multiple output (MIMO) systems for health-care applications has been developed, simulated and implemented. The system can accept various measurements via sensors placed on patients or elders and transmit information wirelessly to base station at a remote location. A microcontroller is used to control and process the signals submitted from sensor-enabled RFID devices using sequential logic. Processed signals are then sent to single receiver and transmitter pair instead of conventional MIMO antenna systems. This reduces the cost significantly in comparison to existing systems. It has been shown that the data transmitted from measurement locations can be acquired at the base station located 20 mile away. Data acquisition system (DAQ) is used to determine the measured value, apply the required statistics and display information to health-care professional at the base station. The system developed can be used for health-care applications including nursing homes in rural areas where access is difficult.
Investigation of the Effects of Zebularine on Caspase-3 and Caspase-9 Involved in Anticancer and Apoptotic Mechanisms in SKBR3 Breast Cancer Cell Line  [PDF]
Onur Eroglu, Merve Celen
Journal of Cancer Therapy (JCT) , 2019, DOI: 10.4236/jct.2019.103019
Abstract: The aim of this study is to investigate the anti-proliferative effects of Zebularine on caspase-3 and 9 genes by methylation and protein expression on SKBR3 cells. The SKBR3 cells were treated with Zebularine at different concentrations (0 - 140 μM) for 24 - 96 hours and the effects on the cell viability were shown. The effects on the cell migration and cell transformation were also demonstrated at the specified dose (IC50 = 40 μM). At the same time, the HRM method and western-blot analysis were used to understand the effects in the apoptotic mechanism. According to the obtained results, it was observed that Zebularine significantly decreased the cell proliferation, cell migration and the cell growth (p < 0.001). As a result of the methylation analyzes performed on SKBR-3 cells at the applied dose, it was observed that Zebularine caused a decrease in both caspase-3 and 9 methylation rates at the 72nd hour. However, both reductions in the methylation levels didn’t cause a significant change (p > 0.05). At the same time, it was detected by the western-blot analyses that there was a time dependent increase in caspase-3 genes while a decrease was detected in the caspase-9 gene in progress of time. The obtained results showed that the methylation changes occurring in the caspase genes weren’t related to the protein levels. According to these results, supportive results are obtained showing that the Zebularine c
The 2008 Global Financial Crisis and The Liquidity Management of The Central Bank of The Republic of Turkey
Nadir Eroglu,Ilhan Eroglu
International Journal of Economics and Finance , 2011, DOI: 10.5539/ijef.v3n2p186
Abstract: The most typical feature of financial crises is that the money demand of almost all economic units increases and they wish to keep their properties as cash that is the most liquid asset. This is caused by the loss of confidence between economic units. In the 2008 Financial Crisis, this feature has come into prominence and a shortage of liquidity and credit that affected all countries has appeared. Avoiding the negative effects of the financial crisis is only possible through a good liquidity management. Central banks of the USA, Europe and other developed and developing countries have taken several measures in order to solve the shortage of liquidity. The Central Bank of the Republic of Turkey (CBRT) has also made some regulations in the financial crisis. The aim of this study is to investigate the essential dynamics of the 2008 Financial Crisis and evaluate the liquidity management that the CBRT has followed against the financial crisis.
Design of the Model Predictive Control Education and Application Interface  [PDF]
Eray Yilmazlar, Erkan Kaplano?lu
Journal of Software Engineering and Applications (JSEA) , 2012, DOI: 10.4236/jsea.2012.59080
Abstract: In this study, an education and application interface was designed for model predictive control (MPC). For this design, MPC Toolbox and MATLAB GUI in the MATLAB software were used. Developed interface includes model predictive control methods, such as single-input single-output, multi-input multi-output, constrained or unconstrained systems. The interface, developed for education of model predictive control methods, was tested in class by the students attending to the Process Dynamic and Control course.
Some QSAR Studies for a Group of Sulfonamide Schiff Base as Carbonic Anhydrase CA II Inhibitors
Erol Eroglu
International Journal of Molecular Sciences , 2008, DOI: 10.3390/ijms9020181
Abstract: In the present study, quantitative structure–activity-relationship (QSAR) study on a group of sulfonamide Schiff-base inhibitors of Carbonic Anhydrase (CA) enzyme has been carried out using Codessa Pro methodology and software. Linear regression QSAR models of the biological activity (Ki) of 38 inhibitors of carbonic anhydrase CA-II isozyme were established with 12 different molecular descriptors which were selected from more than hundreds of geometrical, topological, quantum-mechanical, and electronic types of descriptors and calculated using Codessa Pro software. Among the models presented in this study, statistically the most significant one is a five-parameter equation with correlation coefficient, R2 values of ca. 0.840, and the cross-validated correlation coefficient, R2 values of ca. 0.777. The obtained models allowed us to reveal some physicochemical and structural factors, which are strongly correlated with the biological activity of the compounds.
Planar Inductor Design for High Power Applications
Abdullah Eroglu
PIER B , 2011, DOI: 10.2528/PIERB11081601
Abstract: Design, simulation, and implementation of low profile microstrip spiral inductors for high power Industrial, Scientific and Medical (ISM) applications at the high frequency (HF-3-30 MHz) range are given for the first time. An accurate analytical model and algorithm have been developed to determine the simplified lumped element equivalent model parameters for spiral inductor and its physical dimensions. Five different spiral inductors are then simulated with a planar electromagnetic simulator using the physical dimensions obtained for the desired inductance values with the analytical method. The implementation method and substrate selection for spiral inductors at the HF range are given in detail for high power applications. The spiral inductors are then constructed on 100 mil Alumina substrate and measured with network analyzer. It is found that analytical, simulation and measurement results are in close agreement and the analytical method and algorithm that have been developed can be used to accurately determine the physical dimensions, and the resonant frequency of the spiral inductor for the desired inductance value.
Some QSAR Studies for a Group of Sulfonamide Schiff Base as Carbonic Anhydrase CA II Inhibitors
Erol Eroglu
International Journal of Molecular Sciences , 2008,
Abstract: In the present study, quantitative structure ¢ € “activity-relationship (QSAR) study on a group of sulfonamide Schiff-base inhibitors of Carbonic Anhydrase (CA) enzyme has been carried out using Codessa Pro methodology and software. Linear regression QSAR models of the biological activity (Ki) of 38 inhibitors of carbonic anhydrase CA-II isozyme were established with 12 different molecular descriptors which were selected from more than hundreds of geometrical, topological, quantum-mechanical, and electronic types of descriptors and calculated using Codessa Pro software. Among the models presented in this study, statistically the most significant one is a five-parameter equation with correlation coefficient, R2 values of ca. 0.840, and the cross-validated correlation coefficient, R2 values of ca. 0.777. The obtained models allowed us to reveal some physicochemical and structural factors, which are strongly correlated with the biological activity of the compounds.
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