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Search Results: 1 - 10 of 211 matches for " Eom "
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Quantificational analysis of NPT-II protein from genetically modified Vitis vinifera L.
SH Eom, BI Reisch
African Journal of Biotechnology , 2010,
Abstract: Widely distributed inhibitors in grapevine extracts make it difficult to improve analytical procedures for protein detection. In this study, acidity in grapevine extracts was one of the major factors inhibiting the detection of neomycin phosphotransferase II via enzyme-linked immunosorbent assay. Leaf and berry extracts with low pH (3.0 – 4.0) strongly inhibited NPT-II detection, while root and xylem sap extracts (normally pH 5.5 to 7.0) allowed the successful detection of NPT-II. The other inhibitory effect against the detection was successfully solved by heat treatment to samples extracted. Boiling leaf extract prior to ELISA, in conjunction with pH adjustment (to 7.0) was essential to improve NPT-II detection, while with berry extracts only pH adjustment was required. In the basis of above results, NPT-II protein contents in transgenic grapevine tissues possessing a NPT-II gene were successfully measured. The results here may be useful to help in evaluation of the bio-safety whether the transgenic grapevines were released or contaminated on the grapevine cultivation area by NPT-II protein detection.
The Performance Improvement of BASK System for Giga-Bit MODEM Using the Fuzzy System  [PDF]
Ki-Hwan Eom, Kyo-Hwan Hyun, Kyung-Kwon Jung
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2010, DOI: 10.4236/ijcns.2010.35058
Abstract: In this paper we propose an automatic bandwidth control method for the performance improvement of Binary Amplitude Shift Keying (BASK) system for Giga-bit Modem in millimeter band. To improve the performance of the BASK system with a fixed bandwidth, the proposed method is to adjust a bandwidth of low pass filter in receiver using the fuzzy system. The BASK system consists of a high speed shutter of the transmitter and a counter and a repeater of receiver. The repeater consists of four stage converters, and a converter is constructed with a low pass filter and a limiter. The inputs to the fuzzy system are the reminder and integral of remainder of counter, and output is a bandwidth. We used a Viterbi algorithm to find the optimum detection from output of the counter. Simulation results show that the proposed system improves the performance compared to the fixed bandwidth.
Characterizing and Modeling Citation Dynamics
Young-Ho Eom, Santo Fortunato
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0024926
Abstract: Citation distributions are crucial for the analysis and modeling of the activity of scientists. We investigated bibliometric data of papers published in journals of the American Physical Society, searching for the type of function which best describes the observed citation distributions. We used the goodness of fit with Kolmogorov-Smirnov statistics for three classes of functions: log-normal, simple power law and shifted power law. The shifted power law turns out to be the most reliable hypothesis for all citation networks we derived, which correspond to different time spans. We find that citation dynamics is characterized by bursts, usually occurring within a few years since publication of a paper, and the burst size spans several orders of magnitude. We also investigated the microscopic mechanisms for the evolution of citation networks, by proposing a linear preferential attachment with time dependent initial attractiveness. The model successfully reproduces the empirical citation distributions and accounts for the presence of citation bursts as well.
RFID Label Tag Design for Metallic Surface Environments
Chong Ryol Park,Ki Hwan Eom
Sensors , 2011, DOI: 10.3390/s110100938
Abstract: This paper describes a metal mount RFID tag that works reliably on metallic surfaces. The method proposes the use of commercial label type RFID tags with 2.5 mm thick Styrofoam103.7 with a relative permittivity of 1.03 attached on the back of the tag. In order to verify the performance of the proposed method, we performed experiments on an electric transformer supply chain system. The experimental results showed that the proposed tags can communicate with readers from a distance of 2 m. The recognition rates are comparable to those of commercial metallic mountable tags.
GSK3β N-terminus binding to p53 promotes its acetylation
Tae-Yeon Eom, Richard S Jope
Molecular Cancer , 2009, DOI: 10.1186/1476-4598-8-14
Abstract: Glycogen synthase kinase-3 (GSK3) phosphorylates more than 40 substrates, so its actions must be controlled in a substrate-specific manner to avoid spurious phosphorylation of unintended substrates upon fluxes in the activity of GSK3 [1]. This must be accomplished by synchronous regulation of GSK3 binding to substrates or substrate-containing protein complexes and regulation of GSK3 activity, such as the activity-regulating serine-phosphorylation of GSK3. Thus, the association of GSK3 in protein complexes is likely as critical as post-translational modifications in controlling the actions of GSK3. This has been well-described for the Wnt signaling pathway where GSK3 must be bound to axin to phosphorylate axin-bound β-catenin [2]. This substrate specificity implies the existence of different GSK3 recognition motifs for various binding partners, but GSK3 binding domain studies have been confined to Wnt signaling proteins [3-5]. Thus, little is known about binding domains in GSK3, and it is usually depicted as three domains, a small N-terminal domain, a slightly larger C-terminal domain, and a predominant middle kinase domain. Additionally, a nuclear localization sequence was recently identified [6].To understand better the protein-protein interactions of GSK3β, we investigated the residues required for GSK3β to bind the tumor suppressor p53 [7]. GSK3β forms a complex with nuclear p53 to promote p53-induced apoptosis, and the C-terminal p53 basic domain is necessary for this interaction [8-10]. GSK3β also interacts with p53 in the nucleus during cellular senescence [11], and GSK3β binds p53 in mitochondria [9]. Although the interaction between GSK3β and p53 has been confirmed in several studies, the functional consequences are controversial, possibly because of the many other regulatory influences on p53 and the context- and cell-specific regulation and actions of p53. GSK3 has been reported to phosphorylate Ser33-p53 [12] or Ser315-p53 and Ser376-p53 [13,14], and to r
Radiation of a Hertzian Dipole in a Short-Ended Conducting Circular Cylinder with Narrow Circumferential Slots
Jang Soo Ock;Hyo-Joon Eom
PIER Letters , 2008, DOI: 10.2528/PIERL07121305
Abstract: Radiation of a Hertzian dipole in a short-ended conducting circular cylinder with narrow circumferential slots is presented. Modematching and Fourier transform were utilized to derive a system of simultaneous equations for modal coefficients. Computations were performed to confirm the fast convergence of the series solution.
Early Rebleeding of Multiple Hemorrhagic Metastatic Choriocarcinoma with Intracerebral Hemorrhage
Ki Seong EOM,Tae Young KIM
Journal of Neurological Sciences , 2012,
Abstract: Choriocarcinoma is a rare, highly malignant gestational trophoblastic neoplasia. This tumor is known for its rapid hematogenous spread to multiple organs and good response to chemotherapy. However, cerebral metastases occur frequently, and hemorrhage from cerebral metastases is a common cause of death. Therefore, patients with cerebral metastases require intensive multimodal therapy to achieve remission. Here, we report the case of a 38-year-old woman with multiple hemorrhagic metastases of choriocarcinoma who developed intracerebral hemorrhage, for which she underwent craniotomy and total removal of the hematoma. Five days after surgery, rebleeding of a large intracerebral hemorrhage developed and an emergency reoperation was performed. We suggest that surgeons carefully consider all patient-related data and always pay attention to changes in the neurological state of a patient. Surgeons should also do their best to completely remove the intracerebral choriocarcinoma in the first operation.
Cystic and Calcified Brain Tumor Metastasized From Non-Small Cell Carcinoma: A Case Report
Ki Seong EOM,Tae Young KIM
Journal of Neurological Sciences , 2012,
Abstract: Although brain metastases from tumors arising outside the central nervous system are relatively common, the calcification of metastatic brain tumors is very rare. Here, the authors report a rare case of 50-year-old woman with a cystic and calcified brain tumor metastasized from non-small cell carcinoma of lung and review the literature. Calcification with cysts in metastatic brain tumors might be an indicator of a relatively long survival in cases of metastatic tumor if the primary tumor is controlled because a long time is required for the formation of calcium deposits.
Preliminary Clinical Experiences of Percutaneous Epidural Adhesiolysis with Racz Catheter for Neural Foraminal Stenosis of the Lumbar Spine
Ki Seong EOM,Tea Young KIM
Journal of Neurological Sciences , 2012,
Abstract: Objectives: The authors evaluated the effectiveness of percutaneous epidural adhesiolysis (PEA) in patients with neural foraminal stenosis without significant central spinal canal stenosis of the lumbar spine.Methods: Seventeen patients with neural foraminal stenosis of the lumbar spine who underwent PEA with Racz catheters were included in the study. Patients were evaluated for pain score, medication intake, significant pain relief, and complications.Results: Pain scores and medication intake were significantly decreased 1 month, 3 months, and 6 months after PEA compared to pre-PEA evaluations. However, older patients with long-standing low back pain experienced little regression of pain. There were no major complications related to the epidural adhesiolysis. Significant pain relief decreased gradually over time from 82.4% at 3 days to 76.5% at 6 months.Conclusions: Although our study had several limitations, these results suggested that PEA for neural foraminal stenosis of the lumbar spine without significant lumbar spinal canal stenosis was a safe and effective procedure. Therefore, PEA may be considered as an initial treatment procedure before invasive operations are performed.
Simple micromechanical model of protein crystals for their mechanical characterizations
Yoon G.,Eom K.,Na S.
EPJ Web of Conferences , 2010, DOI: 10.1051/epjconf/20100605001
Abstract: Proteins have been known to perform the excellent mechanical functions and exhibit the remarkable mechanical properties such as high fracture toughness in spider silk protein [1]. This indicates that the mechanical characterization of protein molecules and/or crystals is very essential to understand such remarkable mechanical function of protein molecules. In this study, for gaining insight into mechanical behavior of protein crystals, we developed the micromechanical model by using the empirical potential field prescribed to alpha carbon atoms of a protein crystal in a unit cell. We consider the simple protein crystals for their mechanical behavior under tensile loading to be compared with full atomic models
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