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Search Results: 1 - 10 of 220084 matches for " Enzo Devoto C. "
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HIPOGONADISMO ASOCIADO A LA SENILIDAD EN EL VARóN (CLIMATERIO MASCULINO - ANDROPAUSIA - ADAM)
Devoto C,Enzo; Aravena C,Lucía;
Revista chilena de obstetricia y ginecología , 2004, DOI: 10.4067/S0717-75262004000500012
Abstract: at present it is accepted that exist in healthy aged men a progressive reduction of the total and free testosterone, arriving 20 - 30% to hypogonadism level. the diagnosis of associated hypogonadism to aging is of exclusion. more studies are required to differentiate if the compatible symptoms with hypogonadism must be to testosterone deficiency, aging or alteration of other endocrine axes
EVOLUCION Y PRONOSTICO DE LOS TRASTORNOS MENSTRUALES EN LA ADOLESCENCIA
Devoto C.,Enzo; Aravena C.,Lucía;
Revista chilena de obstetricia y ginecología , 2002, DOI: 10.4067/S0717-75262002000500016
Abstract: menstrual disturbances are very cycles frecuent during the first 5 years after menarche. high prevalence of anovulatory cycles occur in the first year. in contrast high prevalence of ovulatory cycles occur at 6 years postmenarchal. menstrual disturbances have been associated with hypothalamic-pituitary-ovarian axis madurative phenomenon or pathology of pubertal root as polycystic ovary syndrome. hypothalamic dysfunction is other cause of menstrual disturbances when other diseases have been discarded. this condition is caracterized by a alteration of the gnrh pulse generation system. we report the natural history of reproductive and menstrual evolution in women with hypothalamic dysfunction developed in adolescence
ACTUALIZACIóN DE LA TERAPIA DEL HIRSUTISMO
Devoto C,Enzo; Aravena C,Lucía;
Revista chilena de obstetricia y ginecología , 2006, DOI: 10.4067/S0717-75262006000600010
Abstract: the hirsutism is a symptom of the feminine hiperandrogenism at dermatological level and constitutes in itself an aesthetic and psycho-social problem for the woman. the drugs involved in the treatment, the mechanism of action and the collateral effects are analyzed. the efficiency and security of cyproterone, spironolactone and flutamide in 3 groups of hirsute women are comparing with the literature data
Evolución menstrual y reproductiva favorable en mujeres adultas, que presentaron en la adolescencia trastornos menstruales por disfunción hipotalámica con respuesta alterada al clomifeno
Devoto C,Enzo; Aravena C,Lucía;
Revista médica de Chile , 2002, DOI: 10.4067/S0034-98872002000700005
Abstract: background: hypothalamic dysfunction is a cause of menstrual disturbances in women, in whom other diseases have been discarded. this condition is characterized by a failure of the gnrh pulse generation system and is associated to psychological and environmental factors. a lack of ovulatory response to the administration of clomiphene can be a sign of bad prognosis in hypothalamic dysfunction. aim: to report the natural history of patients with hypothalamic dysfunction and a bad or deficient response to the administration of clomiphene. patients and methods: fifty patients with hypothalamic dysfunction, that consulted for menstrual disturbances at the age of 15 to 20 years old, were studied. all received clomiphene and 31 had an ovulatory response, 12 had menses without ovulation and 7 did not menstruate. of these 19 women eleven were interviewed again about their menstrual and reproductive history, after a lapse of 9 to 17 years of loss from follow up. results: eight of the eleven women had stressful events during adolescence (going away from family house in 3, starting university studies in 3, migration out of the natal country in one and non competitive physical activity in one). all restarted their menses and eight with active sexual life had spontaneous pregnancies, giving birth from two to five children. ovulatory cycles were documented in women without active sexual life. conclusions: in teenagers with hypothalamic dysfunction and menstrual disturbances, a deficient or bad response to clomiphene does not necessarily indicate a bad prognosis in terms of menses or fertility (rev méd chile 2002; 130: 745-52)
Eficacia de la flutamida en el tratamiento del hirsutismo: Contribución del uso combinado con anticonceptivos orales en mujeres normoandrogénicas
Devoto C,Enzo; Aravena C,Lucía;
Revista médica de Chile , 2004, DOI: 10.4067/S0034-98872004000700009
Abstract: background: flutamide is an antiandrogen devoid of other hormonal effects, except for a decrease in the secretion of adrenal androgens such as dehydroepidandrosterone sulphate (dhea-s) and androstenedione. aim: to assess the effectiveness of flutamide in the treatment of hirsutism, used as monotherapy or combined with oral contraceptives (oc). patients and methods: women with peripheral hirsutism (defined as the presence of normal serum androgen levels and normal ovulatory menstrual cycles) were assigned to receive flutamide alone (500 mg/day) or flutamide plus an oc (ethynylestradiol 0.03 mg and desogestrel 150 μg). hirsute with hyperandrogenism (polycystic ovary syndrome) were assigned to receive flutamide plus an oc. the degree of hirsutism was assessed using a clinical score (moncada) at three, six and twelve months of therapy. results: twenty five women with peripheral hirsutism received flutamide alone and 18 receive flutamide plus the contraceptive. eighteen women with polycystic ovary syndrome were studied. at three months, the reduction in hirsutism was 11.2, 15.9 and 24.7% in women with peripheral hirsutism receiving flutamide alone or flutamide plus oc and in hyperandrogenic women receiving flutamide plus oc, respectively. at twelve months, the figures were 57.2, 57.3 and 52.5% respectively. in hyperandrogenic women, at baseline and three months, serum testosterone levels were 0.96 and 0.42 ng/ml and serum dhea-s levels were 2,980 and 1,490 ng/ml respectively. no collateral effects of treatment or elevations in serum transaminase levels were observed. conclusions: flutamide is effective in the treatment of hirsutism in women with normal or elevated androgen levels. adding oc did not improve the efficacy of the drug (rev méd chile 2004; 132: 845-52)
ACTUALIZACIóN DE LA TERAPIA DEL HIRSUTISMO
Enzo Devoto C,Lucía Aravena C
Revista Chilena de Obstetricia y Ginecología , 2006,
Abstract: El hirsutismo es un síntoma del hiperandrogenismo femenino a nivel dermatológico y constituye en sí mismo un problema estético y psicosocial para la mujer. Se analizan las drogas involucradas en el tratamiento, el mecanismo de acción y efectos colaterales. La eficiencia y seguridad de ciproterona, espironolactona y flutamida en 3 grupos de mujeres hirsutas se comparan con los datos de la literatura The hirsutism is a symptom of the feminine hiperandrogenism at dermatological level and constitutes in itself an aesthetic and psycho-social problem for the woman. The drugs involved in the treatment, the mechanism of action and the collateral effects are analyzed. The efficiency and security of cyproterone, spironolactone and flutamide in 3 groups of hirsute women are comparing with the literature data
EVOLUCION Y PRONOSTICO DE LOS TRASTORNOS MENSTRUALES EN LA ADOLESCENCIA
Enzo Devoto C.,Lucía Aravena C.
Revista Chilena de Obstetricia y Ginecología , 2002,
Abstract: Los trastornos menstruales son muy frecuentes en los primeros 5 a os de edad ginecológica, evolucionando desde un alto porcentaje de ciclos anovulatorios en el primer a o postmenárquica a una mayoría de ciclos ovulatorios a los 6 a os de edad ginecológica. Estas irregularidades menstruales pueden corresponder a un proceso de maduración del eje hipotálamo-hipófisis-gonadal, o se alar la aparición de cuadros como el síndrome de ovario poliquístico. Otra gran causa de amenorrea y oligoamenorrea desde la pubertad, es el trastorno funcional hipotalámico, en que excluidos todo otro trastorno endocrino, enfermedad sistémica y cuadro orgánico, una alteración funcional en las neuronas del GNRH produce insuficiencia o disfunción hipotalámica de acuerdo al grado de compromiso de la pulsatilidad del GNRH. Se presenta las características clínicas y evolución de un grupo de pacientes con disfunción hipotalámica diagnosticada en la adolescencia, y reevaluadas en la vida adulta Menstrual disturbances are very cycles frecuent during the first 5 years after menarche. High prevalence of anovulatory cycles occur in the first year. In contrast high prevalence of ovulatory cycles occur at 6 years postmenarchal. Menstrual disturbances have been associated with hypothalamic-pituitary-ovarian axis madurative phenomenon or pathology of pubertal root as polycystic ovary syndrome. Hypothalamic dysfunction is other cause of menstrual disturbances when other diseases have been discarded. This condition is caracterized by a alteration of the GNRH pulse generation system. We report the natural history of reproductive and menstrual evolution in women with hypothalamic dysfunction developed in adolescence
HIPOGONADISMO ASOCIADO A LA SENILIDAD EN EL VARóN (CLIMATERIO MASCULINO - ANDROPAUSIA - ADAM)
Enzo Devoto C,Lucía Aravena C
Revista Chilena de Obstetricia y Ginecología , 2004,
Abstract: Actualmente se acepta que en hombres envejecidos sanos existe un descenso progresivo aunque no universal, de la testosterona total y libre, llegando un 20 a 30 % a rango hipogonádico. El diagnóstico de hipogonadismo asociado a envejecimiento es de exclusión. Se requieren estudios para poder diferenciar si los síntomas compatibles con hipogonadismo se deben a falla testosterónica, envejecimiento o alteración de otros ejes endocrinos At present it is accepted that exist in healthy aged men a progressive reduction of the total and free testosterone, arriving 20 - 30% to hypogonadism level. The diagnosis of associated hypogonadism to aging is of exclusion. More studies are required to differentiate if the compatible symptoms with hypogonadism must be to testosterone deficiency, aging or alteration of other endocrine axes
Efectos adversos del ácido 3,5,3′ Triyodotiroacético en el tratamiento de la obesidad Adverse effects of 3,5,3′ triiodo thyroacetic acid in the treatment of obesity
Enzo Devoto C,Lucía Aravena C
Revista médica de Chile , 2001,
Abstract:
Eficacia de la flutamida en el tratamiento del hirsutismo: Contribución del uso combinado con anticonceptivos orales en mujeres normoandrogénicas Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women
Enzo Devoto C,Lucía Aravena C
Revista médica de Chile , 2004,
Abstract: Background: Flutamide is an antiandrogen devoid of other hormonal effects, except for a decrease in the secretion of adrenal androgens such as dehydroepidandrosterone sulphate (DHEA-s) and androstenedione. Aim: To assess the effectiveness of flutamide in the treatment of hirsutism, used as monotherapy or combined with oral contraceptives (OC). Patients and methods: Women with peripheral hirsutism (defined as the presence of normal serum androgen levels and normal ovulatory menstrual cycles) were assigned to receive flutamide alone (500 mg/day) or flutamide plus an OC (ethynylestradiol 0.03 mg and desogestrel 150 μg). Hirsute with hyperandrogenism (polycystic ovary syndrome) were assigned to receive flutamide plus an OC. The degree of hirsutism was assessed using a clinical score (Moncada) at three, six and twelve months of therapy. Results: Twenty five women with peripheral hirsutism received flutamide alone and 18 receive flutamide plus the contraceptive. Eighteen women with polycystic ovary syndrome were studied. At three months, the reduction in hirsutism was 11.2, 15.9 and 24.7% in women with peripheral hirsutism receiving flutamide alone or flutamide plus OC and in hyperandrogenic women receiving flutamide plus OC, respectively. At twelve months, the figures were 57.2, 57.3 and 52.5% respectively. In hyperandrogenic women, at baseline and three months, serum testosterone levels were 0.96 and 0.42 ng/ml and serum DHEA-s levels were 2,980 and 1,490 ng/ml respectively. No collateral effects of treatment or elevations in serum transaminase levels were observed. Conclusions: Flutamide is effective in the treatment of hirsutism in women with normal or elevated androgen levels. Adding OC did not improve the efficacy of the drug (Rev Méd Chile 2004; 132: 845-52)
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