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Search Results: 1 - 10 of 148 matches for " Emmanouel Economou "
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Neurotrophin-3 and FLT3 Tyrosine Kinase Receptor in Perinatal Life
Ariadne Malamitsi-Puchner,Emmanouel Economou,Theodora Boutsikou,Konstantinos E. Nikolaou,Nikolaos Vrachnis
Mediators of Inflammation , 2005, DOI: 10.1155/mi.2005.53
Abstract: Our aim is to determine—in 30 healthy full-term infants and their mothers—circulating levels of neurotrophin-3 (NT-3) (important for antenatal and postnatal brain development and implicated in the immune response) and FLT3 tyrosine kinase receptor (FLT3) (controlling hematopoiesis and found in the nervous tissue), in the fetal and neonatal life. NT-3 levels, in contrast to FLT3 ones, increased significantly on the fourth postnatal day in relation to the low levels found in the mother, fetus, and day 1 neonate (P=.03, respectively). Maternal and umbilical NT3 levels positively correlated with respective FLT3 levels (P=.003 and P=.03). Circulating NT-3 levels increased in early neonatal life, possibly due to exposure to various stimuli soon after birth. FLT3 levels do not seem to behave accordingly, although these two substances probably synergize.
A Note on the Natural Relocation of Marchalina hellenica (Gennadius) from Pine to Fir Trees  [PDF]
A. E. Tsagkarakis, N. G. Emmanouel
Advances in Entomology (AE) , 2016, DOI: 10.4236/ae.2016.43017
Abstract: Marchalina hellenica (Gennadius) (Hemiptera: Margarodidae) is the most important honeydew producing insect in Greece. It was referred as monophagus, feeding exclusively on pine trees, until 1995 when it was successfully established on fir trees after artificial “inoculation” at Menalo and Helmos mountains. In this scientific note, the first record of natural relocation of M. hellenica from pine to fir trees is referred.
Malignant Fibrous Histiocytoma of the Breast: A Case Report
Dimosthenis Miliaras,Emmanouel Konstantinides
Case Reports in Pathology , 2012, DOI: 10.1155/2012/579245
Abstract: This paper concerns a case of Malignant Fibrous Histiocytoma (MFH) of the Breast in a 73-years-old woman. A lump was found in her right breast, measuring 1.7 cm in diameter. Surgical excision followed, and pathology revealed a highly atypical spindle cell tumor. Immunohistochemistry along the histological features, excluded the possibility of carcinoma, malignant phyllodes tumor, or another type of pure sarcoma. There was no history of previous irradiation in the region. MFH is among the rarest types of sarcoma of the breast, and most of the times behaves aggressively. Excision with wide, free-of-tumor margins is the most effective treatment, when feasible.
Malignant Fibrous Histiocytoma of the Breast: A Case Report
Dimosthenis Miliaras,Emmanouel Konstantinides
Case Reports in Pathology , 2012, DOI: 10.1155/2012/579245
Abstract: This paper concerns a case of Malignant Fibrous Histiocytoma (MFH) of the Breast in a 73-years-old woman. A lump was found in her right breast, measuring 1.7?cm in diameter. Surgical excision followed, and pathology revealed a highly atypical spindle cell tumor. Immunohistochemistry along the histological features, excluded the possibility of carcinoma, malignant phyllodes tumor, or another type of pure sarcoma. There was no history of previous irradiation in the region. MFH is among the rarest types of sarcoma of the breast, and most of the times behaves aggressively. Excision with wide, free-of-tumor margins is the most effective treatment, when feasible. 1. Introduction The most common malignant tumor of the breast is by far the invasive carcinoma of the ductal or lobular type. In contrast, sarcomas are rare and may be primary or metastatic, and pure or fibroepithelial, that is, malignant phyllodes tumor. The frequency of breast sarcomas in total is less than 1% of all the malignant tumors of the breast [1, 2]. Pure sarcomas could be angiosarcomas, osteosarcomas, liposarcomas, leiomyosarcomas, fibrosarcomas, rhabdomyosarcomas, dermatofibrosarcomas protuberans or malignant fibrous histiocytomas [3, 4]. Among them angiosarcoma is known to be the most frequent sarcoma type of the breast, while malignant fibrous histiocytoma (MFH) seems to be one of the rarer types. Breast sarcomas mostly appear in the fourth and fifth decade of life. Mean age is around 40 years old [4]. Gradually progressive swelling is the commonest presenting feature. Herein we describe the characteristics of a case with MFH of the breast with early detection. 2. Case Report The present case concerned a white female, 73 years old. A lump was found by clinical examination in her right breast. On mammography the tumor was 1.7?cm in diameter and appeared as relatively circumscribed lesion. She was operated upon for this lump, and she had intraoperative frozen sections. The latter revealed a high-grade malignant tumor. A wide excision of the tumor along with ipsilateral axillary fat dissection followed. 25 Lymph nodes, 0.9–0.3?cm in diameter, were removed from the axillary fat. Paraffin sections showed a tumor composed of spindle cells, arranged in interlacing fascicles (Figure 1). Neoplastic cells presented pleomorphic nuclei, giant cell forms, and many and atypical mitoses. Malignant cells were infiltrating between pre-existing benign ducts in the periphery of the tumor (Figure 2). No intraepithelial lesion in the intratumor or the adjacent breast ducts was detected. Subsequently,
Primary and secondary memory differences as a function of age and education
Economou Alexandra
Annals of General Psychiatry , 2006, DOI: 10.1186/1744-859x-5-s1-s178
Abstract:
Current advances of genetics in Inflammatory Bowel Disease
M. Economou
Annals of Gastroenterology , 2007,
Abstract: Genetic factors play an important role in the pathogenesis of inflammatory bowel diseases (IBD), including both ulcerative colitis (UC) and Crohn s disease (CD). The research on genetic susceptibility of IBD has been tremendous and over 10 chromosomal regions have been identified by genome-wide scanning. The certain replicated linkage region in different studies, IBD1 (16q12), contains the CD susceptibility gene, NOD2/CARD15. Further fine mapping as well as candidate gene studies have already led to the identification of a number of other susceptibility genes including DLG5, OCT1 and 2, NOD1, HLA, and TLR4. Recent studies, particularly in CD, have highlighted a number of associations between genotype and phenotype. These, suggest that genetics also may influence the clinical manifestations of IBD including disease location, behavior, natural history and side effects of drug therapy. Genetic research in IBD has helped our understanding of the clinical heterogeneity of the disease and has started to explore the complex interactions between genetic risk factors and environmental risk factors in IBD. Although rapid advances in genomic medicine are yet to impact on routine clinical practice, it is anticipated that genetic markers in the future will be implemented in an integrated molecular diagnostic, therapeutic and prognostic approach of IBD patients.
A Thermoelectric Generator Using Porous Si Thermal Isolation
Emmanouel Hourdakis,Androula G. Nassiopoulou
Sensors , 2013, DOI: 10.3390/s131013596
Abstract: In this paper we report on a thermoelectric generator (TEG) using thermal isolation provided by a thick porous Si layer locally formed on the Si wafer and thermocouples composed of p-doped polycrystalline Si/Al. The “hot” contacts of the thermocouples lie on the porous Si layer, while the “cold” contacts lie on bulk crystalline Si. A housing was also designed and fabricated in order to transfer any external temperature change on the “hot” contacts of the thermocouples, the “cold” contacts being isolated from the “hot” contacts by a thick resist layer. The fabrication of the sensing element (Si die) is fully compatible with batch Si processing. The output power of the thermoelectric generator depends on the porous Si isolation layer thickness, porosity, structure and morphology. For a mesoporous Si layer of 60% porosity and a macroscopic temperature differential of 10 K, an output power of 0.39 μW/cm 2 was measured for a 50 μm thick porous Si layer.
Exploring the useful exposure range limits of three intraoral image receptors for various tube potential, tube current and exposure time settings  [PDF]
Elli Katsoni, Ioannis A. Tsalafoutas, Panagiotis Gritzalis, Evripides Stefanou, Evangelos Georgiou, Emmanouel Yakoumakis
Health (Health) , 2011, DOI: 10.4236/health.2011.35051
Abstract: Objectives: To determine the useful exposure range limits of three intraoral image receptors of different technology when exposed to different X-ray beam spectra, dose and dose rate levels. Study Design: A dental X-ray unit offering a wide range of tube potential, tube current and exposure time settings was used to expose a dental quality control phantom. The receptors that were used to capture the radiographic images of the phantom were: the Kodak Insight, the Kodak RVG-6000 and the Duerr Vistascan system. The images that were produced over a wide range of exposure factor settings were evaluated in terms of diagnostic quality by three experienced radiologists. Results: The number of images with acceptable diagnostic quality was in total 1257; 310 with Insight, 331 with RVG 6000 and 616 with Vistascan. At 60 kV, diagnosable images were produced with doses ranging from 0.44-1.56 mGy for the Insight film 0.44-2.82 mGy for the RVG 6000 and 0.22-4.93 mGy for the Vistascan system. At 70 kV, the respective ranges were 0.39-1.28 mGy for the Insight film 0.31-2.55 mGy for the RVG6000 and 0.30-3.46 mGy for the Vistascan system. Conclusions: The Vistascan exhibited the widest useful exposure range and required the least exposure to produce a diagnosable image at almost all tube potential settings. The RVG 6000 exhibited a slightly wider useful exposure range than the Insight film, with almost the same dose requirements especially in higher Kv settings.
Novel Air Flow Meter for an Automobile Engine Using a Si Sensor with Porous Si Thermal Isolation
Emmanouel Hourdakis,Panagiotis Sarafis,Androula G. Nassiopoulou
Sensors , 2012, DOI: 10.3390/s121114838
Abstract: An air flow meter for measuring the intake air of an automobile engine is presented. It is based on a miniaturized silicon thermal mass flow sensor using a thick porous Si (Po-Si) layer for local thermal isolation from the Si substrate, on which the sensor active elements are integrated. The sensor is mounted on one side of a printed circuit board (PCB), on the other side of which the readout and control electronics of the meter are mounted. The PCB is fixed on a housing containing a semi-cylindrical flow tube, in the middle of which the sensor is situated. An important advantage of the present air flow meter is that it detects with equal sensitivity both forward and reverse flows. Two prototypes were fabricated, a laboratory prototype for flow calibration using mass flow controllers and a final demonstrator with the housing mounted in an automobile engine inlet tube. The final demonstrator was tested in real life conditions in the engine inlet tube of a truck. It shows an almost linear response in a large flow range between –6,500 kg/h and +6,500 kg/h, which is an order of magnitude larger than the ones usually encountered in an automobile engine.
Quality Classifiers for Open Source Software Repositories
George Tsatsaronis,Maria Halkidi,Emmanouel A. Giakoumakis
Computer Science , 2009,
Abstract: Open Source Software (OSS) often relies on large repositories, like SourceForge, for initial incubation. The OSS repositories offer a large variety of meta-data providing interesting information about projects and their success. In this paper we propose a data mining approach for training classifiers on the OSS meta-data provided by such data repositories. The classifiers learn to predict the successful continuation of an OSS project. The `successfulness' of projects is defined in terms of the classifier confidence with which it predicts that they could be ported in popular OSS projects (such as FreeBSD, Gentoo Portage).
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