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Search Results: 1 - 10 of 1970 matches for " Emma Marxer-Tobler "
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Neuroanthropology: Olfactory Recognition of the Self / Non-self by the Ancestral MHC: An EEG Study
Emma Marxer-Tobler,Jaime Pineda
International Journal of Biology , 2012, DOI: 10.5539/ijb.v4n4p1
Abstract: Humans naturally discriminate between different ethnic group members using visual and other sensory information, including the sense of smell. The genetic diversity of humans serves as biological and social sign stimuli in the neural self/non-self recognition process. As already evident, the major histocompatibility complex (MHC) encodes both an individual self and a shared ancestral self into the body odor. In a pilot study, we examine the brain-evoked responses to ancestral encoded body odors by conducting an olfactory EEG recording of four different groups: Germans, Taiwanese, Koreans, and Chinese. Results show that humans recognize in-group members as familiar and they exhibit practically identical rhythmic EEG patterns to one’s own odor as it pertains to the ancestral in-group odors. This reveals their genetic relatedness. It is hereby demonstrated that shared ethnicity results in behaviors (both group-protective and pro-social) that are important to intra- and inter-group dynamics.
Unsupervised Incremental Learning and Prediction of Music Signals
Ricard Marxer,Hendrik Purwins
Computer Science , 2015,
Abstract: A system is presented that segments, clusters and predicts musical audio in an unsupervised manner, adjusting the number of (timbre) clusters instantaneously to the audio input. A sequence learning algorithm adapts its structure to a dynamically changing clustering tree. The flow of the system is as follows: 1) segmentation by onset detection, 2) timbre representation of each segment by Mel frequency cepstrum coefficients, 3) discretization by incremental clustering, yielding a tree of different sound classes (e.g. instruments) that can grow or shrink on the fly driven by the instantaneous sound events, resulting in a discrete symbol sequence, 4) extraction of statistical regularities of the symbol sequence, using hierarchical N-grams and the newly introduced conceptual Boltzmann machine, and 5) prediction of the next sound event in the sequence. The system's robustness is assessed with respect to complexity and noisiness of the signal. Clustering in isolation yields an adjusted Rand index (ARI) of 82.7% / 85.7% for data sets of singing voice and drums. Onset detection jointly with clustering achieve an ARI of 81.3% / 76.3% and the prediction of the entire system yields an ARI of 27.2% / 39.2%.
A Short Note
Waldo Tobler
Solstice : Electronic Journal of Geography and Mathematics , 2012,
Abstract:
Spherical Measures without Spherical Trigonometry
Waldo Tobler
Solstice : Electronic Journal of Geography and Mathematics , 2001,
Abstract: The link to the fulltext on a current website is given below. Should that link fail to work, please go to this persistent URL and download the associated file for this issue. http://deepblue.lib.umich.edu/handle/2027.42/58219While you are there, take a look around and see if there are other issues and documents that are related to your interests!
Using Asymmetry to Estimate Potential
Waldo Tobler
Solstice : Electronic Journal of Geography and Mathematics , 2005,
Abstract: The link to the fulltext on a current website is given below. Should that link fail to work, please go to this persistent URL and download the associated file for this issue. http://deepblue.lib.umich.edu/handle/2027.42/58219While you are there, take a look around and see if there are other issues and documents that are related to your interests!
Looking at some Data from Isard
Waldo Tobler
Solstice : Electronic Journal of Geography and Mathematics , 2006,
Abstract: The link to the fulltext on a current website is given below. Should that link fail to work, please go to this persistent URL and download the associated file for this issue. http://deepblue.lib.umich.edu/handle/2027.42/58219While you are there, take a look around and see if there are other issues and documents that are related to your interests!
Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula
Marxer Monika,Ingram Katrin,Keiser Jennifer
Parasites & Vectors , 2012, DOI: 10.1186/1756-3305-5-165
Abstract: Background The development of novel antischistosomal drugs is crucial, as currently no vaccine and only a single drug is available for the treatment of schistosomiasis. Fast and accurate in vitro assays are urgently needed to identify new drug candidates and research efforts should include Schistosoma haematobium. The aim of the present study was to develop a S. haematobium drug sensitivity assay based on newly transformed schistosomula (NTS). Methods We first undertook comparative studies on the cercarial emergence rhythms of the intermediate host snails Biomphalaria glabrata (S. mansoni) and Bulinus truncatus (S. haematobium). Two transformation methods as well as three purification methods were studied on S. haematobium cercariae in order to produce a large number of viable and clean NTS. Known antischistosomal drugs were tested in the established NTS assay in vitro. Drug effects were evaluated either microscopically or fluorometrically, using a resazurin based viability marker. Microscopically obtained IC50 values were compared with results obtained for S. mansoni. Results A circadian rhythm existed in both snail species. Infected B. truncatus snails shed less cercariae than B. glabrata during the testing period. The highest transformation rate (69%) of S. haematobium cercariae into NTS was obtained with the vortex transformation (mechanical input) and the highest purification factor was observed using Percoll . The fluorimetric readout based on resazurin was very precise in detecting dead or/and severely damaged schistosomula. Conclusions With the use of viability markers such as resazurin, drug screening assays using S. haematobium NTS can be efficiently performed. However, drugs acting on the morphology and motility of S. haematobium NTS, such as metrifonate are missed. Drug sensitivity assays with NTS of both species, S. haematobium and S. mansoni, showed very similar results using known antischistosomal drugs. The S. mansoni NTS assay might be more suitable as primary screen in drug discovery efforts, which ultimately aim for a broad-spectrum antischistosomal drug as a larger number of S. mansoni NTS can be generated.
Improving the passive doppler geolocation system through extension of the data reception network
Sousa, Cristina Tobler de;
Revista Brasileira de Geofísica , 2008, DOI: 10.1590/S0102-261X2008000400001
Abstract: the main goal of this work is to show an investigation on the improvement of the newly developed doppler based brazilian geographic location system using the data reception network software. the doppler data measurement set of a single satellite pass and a single dcp (data collecting platform), considering a network of ground reception stations, is named as the data reception network. thus, increasing the terrestrial reception stations around the brazilian territory, will allow an increment in the coverage and amount of data collected. consequently the accuracy of the computed locations would also increase as well as the reliability figures. the results and analyses were obtained under two conditions: the first one used both ideal simulated and real conditions to compare results from the same satell ite passes, dcp and two known ground reception stations, the second one used ideal simulated conditions from measurements of one dcp transmitter, three ground stations and two satellites. results using such database were quite satisfactory. the achieved study showed the importance of additional terrestrial reception stations spread over the brazilian territory, to increase the measurements amount, as well as to get more valid and precise locations.
The geographic movement of wealth in the United States
Waldo R. TOBLER
Mappemonde , 1986,
Abstract: Un modèle numérique appliqué aux densités et aux flux de richesses aux états-Unis en 1970 et 1976 tend à montrer que ces richesses se déplacent avec la population. Les cartes illustrant ces flux sont proches de celles du mouvement net de population aux mêmes dates.
Visual evidence for urban potential fields
Waldo R. TOBLER
Mappemonde , 1991,
Abstract: A satellite picture of adjacent cities clearly illustrates the analytical dynamics of urban growth.
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