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Search Results: 1 - 10 of 1120 matches for " Elisabetta Pilotto "
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Hyperreflective Intraretinal Spots in Diabetics without and with Nonproliferative Diabetic Retinopathy: An In Vivo Study Using Spectral Domain OCT
Stela Vujosevic,Silvia Bini,Giulia Midena,Marianna Berton,Elisabetta Pilotto,Edoardo Midena
Journal of Diabetes Research , 2013, DOI: 10.1155/2013/491835
Abstract: Purpose. To evaluate the presence of hyperreflective spots (HRS) in diabetic patients without clinically detectable retinopathy (no DR) or with nonproliferative mild to moderate retinopathy (DR) without macular edema, and compare the results to controls. Methods. 36 subjects were enrolled: 12 with no DR, 12 with DR, and 12 normal subjects who served as controls. All studied subjects underwent full ophthalmologic examination and spectral domain optical coherence tomography (SD-OCT). SD-OCT images were analyzed to measure and localize HRS. Each image was analyzed by two independent, masked examiners. Results. The number of HRS was significantly higher in both diabetics without and with retinopathy versus controls ( ) and in diabetics with retinopathy versus diabetics without retinopathy ( ). The HRS were mainly located in the inner retina layers (inner limiting membrane, ganglion cell layer, and inner nuclear layer). The intraobserver and interobserver agreement was almost perfect ( ). Conclusions. SD-OCT hyperreflective spots are present in diabetic eyes even when clinical retinopathy is undetectable. Their number increases with progressing retinopathy. Initially, HRS are mainly located in the inner retina, where the resident microglia is present. With progressing retinopathy, HRS reach the outer retinal layer. HRS may represent a surrogate of microglial activation in diabetic retina. 1. Introduction An increasing body of evidence suggests that retinal neurodegeneration and inflammation occur in human diabetes even before the development of clinical signs of diabetic retinopathy (DR) [1]. Retinal neural cell loss (neurodegeneration) has already been demonstrated in vivo (as thinning of retinal nerve fiber and ganglion cell layers), both in type 1 and 2 diabetes [2–7]. Retinal microglia activation has been recognized as the main responsible for the initial inflammatory response, even though the exact mechanism through which inflammatory cytokines are released remains poorly known [8]. Some experimental studies have shown that retinal inflammation occurring during the course of diabetes mellitus is a relatively early event and that it precedes both vascular dysfunction and neuronal degeneration [1, 8]. Joussen at al. demonstrated in animal models of diabetes mellitus that ICAM-1- and CD18-mediated leukocyte adhesion is increased in the retinal vasculature and accounts for many of the signature lesions of DR [1]. Ibrahim et al. demonstrated in rats that the accumulation of Amadori-glycated albumin (AGA) within the 8-week diabetic retina elicits microglial
A CONCEP O HUSSERLIANA DE CORPOREIDADE: A DISTIN O FENOMENOLóGICA ENTRE CORPO PRóPRIO E CORPOS INANIMADOS THE HUSSERLIAN CONCEPTION OF CORPORALITY: A PHENOMENOLOGICAL DISTINCTION BETWEEN PERSONAL BODY AND INANIMATE BODIES
ARON PILOTTO BARCO
Synesis , 2012,
Abstract: Resumo: Ao contrário do que as diversas aproxima es entre Husserl e Descartes podem sugerir, Husserl foi um severo crítico do dualismo mente-corpo, de origem cartesiana. Esse texto tem por objetivo explicar o conceito husserliano de corporeidade para assim expor como o autor defende uma concep o n o dualista da corporeidade. Para Husserl n o se trata de propor ‘eu tenho um corpo’ – o que pressup e um componente anímico possuidor –, mas sim ‘eu sou um corpo’.Abstract: Contrary to what may suggest the many comparisons between Husserl and Descartes, Husserl were a severe critic of the Cartesian mind-body dualism. This text aims at explain the Husserlian concept of corporeality in order to expose how well the author argues for a non-dualistic conception of corporeality. For Husserl is not about propose ‘I have a body’ – which implies a component possessor soul – but ‘I am a body’.
A Wood Preservative Based on Commercial Silica Nanodispersions and Boric Acid against Fungal Decay through Laboratory and Field Tests  [PDF]
Sabrina Palanti, Elisabetta Feci
Open Journal of Forestry (OJF) , 2013, DOI: 10.4236/ojf.2013.32009
Abstract:

The paper is based on the development of a wood preservative without metal salts to be used in use classes 3 and 4 (EN 335), eco-friendly and harmless to humans and animals. Boric acid was used as a biocide, due to its effectiveness against fungi and insects. It is also known to be easily leached from wood exposed to weather action. Colloidal silica was therefore added in the formulations to guarantee the fixation of boric acid to wood. The different formulations were tested for the protective efficacy against decay fungi through laboratory tests (EN 113) and field trials (EN 252). The results were promising, especially those concerning boron fixation and efficacy against decay fungi through laboratory tests, where some formulations and retentions gave a durability class 1 (very durable) according to EN 350-1. The fourth evaluation, after 50 months of field trials showed only a slight difference between the treated samples and controls.

 

 

Proton induced $K^+$ production and the $s\bar{s}$ content of the proton
Frieder Kleefeld,Fernando Pilotto,Manfred Dillig
Physics , 1998,
Abstract: We investigate the exclusive proton-induced $K^+$ production near the kaon threshold. Compared are two models: a meson-exchange model, which includes $\pi$, \rho$, $K$ and $K^\ast$ exchange, together with the dominant baryon resonances, and a quark-gluon model, where momentum sharing is provided via the exchange of two gluons. Based on covariant bound state wave functions for the meson and the baryons - which we treat as quark-diquark objects - first results for the $pp\to p\Lambda K^+$ total cross section are presented for both models.
Measuring the Horizon: Objectivity, Subjectivity and the Dignity of Human Personal Identity  [PDF]
Francis J. Ambrosio, Elisabetta Lanzilao
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.34A006
Abstract: It is argued in what follows that “culture warfare” is symptomatic of an imminent threat to the continued sustainability of human culture as a whole. The nature of this threat can be characterized as trauma induced paralysis of the human cultural imagination, without which cooperative adaptation to potential credible dangers of self-induced species or even planetary life extinction is impossible. The structure of this paradoxical “possible impossibility” as the destiny of humanity is examined here within the context of an interpretive framework which is broadly characterized as “cultural genetics”. On the basis of a schematic and preliminary outline of that framework, a suggestion is made regarding the direction in which hope of avoiding that destiny might be sought.
Complete III Cranial Nerve Palsy in a Leather Worker: An Unusual Case Report  [PDF]
Adriano Magli, Elisabetta Chiariello Vecchio
Open Journal of Ophthalmology (OJOph) , 2014, DOI: 10.4236/ojoph.2014.43014
Abstract:

This case report describes features and surgical management in one patient that developed a worsening total III cranial nerve palsy in his right eye. Our 45 year-old male patient worked for about 25 years in leather tanning industry. He underwent medical history, routine blood test, eye exams that included visual acuity measurement, slit-lamp examination, dilated retinal biomicroscopy and indirect ophthalmoscopy, fundus photography, tonometry, corneal pachymetry, Krimsky test, oculomotor examination and eye deviation surgery. On examination of the fellow eye wasn’t found any disease. Stroke, aneurysm and intracerebral causes of third nerve palsy were excluded, and medical history was negative for diabetes, cardiovascular disease, trauma, neurological disease unless two previous polyneuropathies episodes and one herpetic keratitis episode. Result of any neuroimaging studies were recorded (Our patients performed in hospital CT, MRI and MRI angiography and all the testes were normal). To our knowledge third cranial nerve palsy has never been observed in literature in leather workers. In conclusion, it is important for ophthalmologists to evaluate carefully work history and lifestyle persons and plan the surgical approach focusing the different characteristics of these patients.

The Relationship of Positive Affect with Resilience and Self-Efficacy in Life Skills in Italian Adolescents  [PDF]
Elisabetta Sagone, Maria Luisa Indiana
Psychology (PSYCH) , 2017, DOI: 10.4236/psych.2017.813142
Abstract: The main purpose of this study was to analyze the relationships of positive affect with dimensions of resilience and perceived self-efficacy in life skills in a sample of 147 Italian healthy adolescents. We used the Positive and Negative Affect Schedule (PANAS), the Resiliency Attitudes and Skills Profile (RASP), and the Perceived Self-Efficacy Scales in Life Skills. Statistical analyses indicated that adolescents with high positive affect reported higher levels of perceived self-efficacy in life skills than those with low positive affect; in addition, adolescents with high positive affect reached higher levels of resilience (that is, adaptability and engagement) than those with low positive affect. Given the relationship of positive affect both with dimensions of resilience and perceived self-efficacy in life skills, future investigations could better understand the functioning of protective factors actively engaged in facing up to the transition from childhood to adolescence, in line with the flourishing approach in supporting the promotion of psychological well-being and the increasing of individual’s bio-psycho-social skills.
Calcium ion currents mediating oocyte maturation events
Elisabetta Tosti
Reproductive Biology and Endocrinology , 2006, DOI: 10.1186/1477-7827-4-26
Abstract: Oogenesis is characterized by a unique process of cell division occurring only in gametes, called meiosis; whose goal is the production of haploid cells highly specialized for fertilization. In the majority of species the oocyte arrests in different stages of meiotic division, in particular, the block occurring in the first meiotic prophase (PI) marks the state of immature oocyte characterized by a prominent nucleus called the germinal vesicle (GV), which contains de-condensed transcriptionally active chromatin [[1] for a review]. As a general scheme, in response to a stimulus, meiosis is resumed and manifested by a germinal vesicle breakdown (GVBD), it then progresses to metaphase I (MI) or II (MII) where it undergoes a second arrest that is removed after successful fertilization.Oocyte maturation is usually defined as the period of progression from the first to the second meiotic arrest and involves coordinated nuclear and cytoplasmic modifications [2]. These are highly complex processes and their interplay is regulated by a series of sequential molecular events. Nuclear maturation starts with the GVBD, ends at the meiosis exit, and is marked by the presence of the two polar bodies. Cytoplasmic maturation is a more obscure process and involves both morphological and functional alterations related to: i) changes in the expression profile of cell cycle control proteins responsible for driving the oocyte towards developmental competencies [3-5]; ii) relocation of organelles [6-8]; iii) transcriptional modifications of mRNA [9], modification of the plasma membrane permeability [10,11]; iv) the differentiation of the calcium signalling machinery [12].Although the arrest at the PI stage seems to be strictly correlated with the oocyte growth, the meiotic stage correlated with fertilizable oocyte is species-specific. In some animals, oocytes are fertilized at the PI stage (anellida, plateyhelminthes, polychaeta, mollusca, arthropoda, echinoderms, and some mammals) or, on
Travelling Through a Sea of Poppies: from the Geographical to the Cultural Frontier In viaggio attraverso un Mare di Papaveri: dal superamento della frontiera geografica al superamento della frontiera culturale
Elisabetta Zurru
Between , 2011,
Abstract: The paper focuses on the relation between the concepts of geographical and cultural frontiers, using Sea of Poppies (2008), Amitav Ghosh’s last novel, as a case study. Indeed, the journey of the ship Ibis from the Gulf of Bengal to the Mauritius islands provides the backdrop against which the theme of the crossing of religious, social and caste boundaries is developed: as the Ibis crosses the frontier which divides India from the Mauritius, the men and women on board, embodiments of both colonizing and colonized values, are subjected to a series of (religious, linguistic, social) negotiation processes. The aim of the paper will be to analyze some of these processes in order to show that in the novel negotiation and contamination become synonymic with cultural resource and new beginnings. The paper focuses on the relation between the concepts of geographical and cultural frontiers, using Sea of Poppies (2008), Amitav Ghosh’s last novel, as a case study. Indeed, the journey of the ship Ibis from the Gulf of Bengal to the Mauritius islands provides the backdrop against which the theme of the crossing of religious, social and caste boundaries is developed: as the Ibis crosses the frontier which divides India from the Mauritius, the men and women on board, embodiments of both colonizing and colonized values, are subjected to a series of (religious, linguistic, social) negotiation processes. The aim of the paper will be to analyze some of these processes in order to show that in the novel negotiation and contamination become synonymic with cultural resource and new beginnings.
Fabio Vittorini, Il sogno all’opera. Racconti onirici e testi melodrammatici
Elisabetta Abignente
Between , 2012,
Abstract: Uno dei tratti caratteristici del libretto d’opera è quello di essere un componimento quasi del tutto privo di originalità. Frutto di un più o meno mediato processo di adattamento da una precedente opera letteraria – può trattarsi di tragedia, commedia, romanzo, racconto, cronaca, fiaba – il testo melodrammatico si pone inevitabilmente come un prodotto letterario di secondo grado, una riscrittura dunque, che sembra rinunciare però ad ogni forma di tensione agonistica col modello.
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