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Search Results: 1 - 10 of 1503 matches for " Eli Rohn "
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CAS-Based Approach for Automatic Data Integration  [PDF]
Eli Rohn
American Journal of Operations Research (AJOR) , 2013, DOI: 10.4236/ajor.2013.31A017
Abstract:

Research of automatic integration of structured and semi-structured data has not resulted in success over the past fifty years. No theory of data integration exists. It is unknown what the theoretical necessary requirements are, to fully support automatic data integration from autonomous heterogeneous data sources. Therefore, it is not possible to objectively evaluate if and how much new algorithms, techniques, and specifically Data Definition Languages, move towards meeting such theoretical requirements. To overcome the serious reverse salient the field and industry are in, it will be helpful if a data integration theory would be developed. This article proposes a new look at data integration by using complex adaptive systems principles to analyze current shortcomings and propose a direction that may lead to a data integration theory.

Autonomous Data Exchange: The Malady and a Possible Path to Its Cure  [PDF]
Eli Rohn
Intelligent Information Management (IIM) , 2015, DOI: 10.4236/iim.2015.71003
Abstract: Data exchange is a goal-oriented social communications system implemented through computerized technology. Data definition languages (DDLs) provide the syntax for communicating within and between organizations, illocutionary acts, such as informing, ordering and warning. Data exchange results in meaning-preserving mapping between an ensemble (a constrained variety) and its external (unconstrained) variety. Research on unsupervised structured and semi-structured data exchange has not produced any significant successes over the past fifty years. As a step towards finding a solution, this article proposes a new look at data exchange by using the principles of complex adaptive systems (CAS) to analyze current shortcomings and to propose a direction that may indeed lead to workable and mathematically grounded solution. Three CAS attributes key to this research are variety, tension and entropy. We use them to show that older and contemporary DDLs are identical in their core, thus explaining why even XML and Ontologies have failed to a create fully automated data exchange mechanism. Then we show that it is possible to construct a radically different DDL that overcomes existing data exchange limitations—its variety, tension and entropy are different from existing solutions. The article has these major parts: definition of key CAS attributes; quantitative examination of representative old and new DDLs using these attributes; presentation of the results and their pessimistic ramification; a section that proposes a new theoretical way to construct DDLs that is based entirely on CAS principles, thus enabling unsupervised data exchange. The theory is then tested, showing very promising results.
Proteolytic Cleavage of Apolipoprotein E4 as the Keystone for the Heightened Risk Associated with Alzheimer’s Disease
Troy T. Rohn
International Journal of Molecular Sciences , 2013, DOI: 10.3390/ijms140714908
Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by microscopic lesions consisting of beta-amyloid plaques and neurofibrillary tangles (NFTs). The majority of cases are defined as sporadic and are likely caused by a combination of both genetic and environmental factors. Of the genetic risk factors identified, the 34 kDa protein, apolipoprotein (apo) E4, is of significant importance as APOE4 carriers account for 65%–80% of all AD cases. Although apoE4 plays a normal role in lipoprotein transport, how it contributes to AD pathogenesis is currently unknown. One potential mechanism by which apoE4 contributes to disease risk is its propensity to undergo proteolytic cleavage generating N- and C-terminal fragments. The purpose of this review will be to examine the mechanisms by which apoE4 contributes to AD pathogenesis focusing on the potential loss or gain of function that may occur following cleavage of the full-length protein. In this context, a discussion of whether targeting apoE4 therapeutically is a rationale approach to treating this disease will be assessed.
Immunolocalization of Influenza A Virus and Markers of Inflammation in the Human Parkinson's Disease Brain
Troy T. Rohn, Lindsey W. Catlin
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0020495
Abstract: Although much is known regarding the molecular mechanisms leading to neuronal cell loss in Parkinson's disease (PD), the initiating event has not been identified. Prevailing theories including a chemical insult or infectious agent have been postulated as possible triggers, leading to neuroinflammation. We present immunohistochemical data indicating the presence of influenza A virus within the substantia nigra pars compacta (SNpc) from postmortem PD brain sections. Influenza A virus labeling was identified within neuromelanin granules as well as on tissue macrophages in the SNpc. Further supporting a role for neuroinflammation in PD was the identification of T-lymphocytes that colocalized with an antibody to caspase-cleaved Beclin-1 within the SNpc. The presence of influenza A virus together with macrophages and T-lymphocytes may contribute to the neuroinflammation associated with this disease.
Conchostráceos com Linhas de Crescimento Recurvadas Junto à Margem Dorsal (Famílias Palaeolimnadiopseidae e Perilimnadiidae) da Forma o Rio do Rasto, Permiano Superior, Bacia do Paraná, Brasil
Luis Gustavo Ferreira-Oliveira,Rosemarie Rohn
Geologia USP : Série Científica , 2008,
Abstract: Alguns conchostráceos permianos da Forma o Rio do Rasto (Bacia do Paraná, Brasil) apresentam um encurvamentobem característico nas linhas de crescimento na regi o próxima à margem dorsal. Todos os exemplares previamente descritosforam atribuídos a Palaeolimnadiopsis subalata (Reed) Raymond. Porém, uma reanálise deste material fóssil e de exemplaresadicionais demonstrou que nem todos os espécimes podem ser incluídos em um mesmo táxon, nem em uma mesma família(Palaeolimnadiopseidae). De acordo com a forma da carapa a e tamanho do umbo, estes exemplares s o aqui referidos atrês espécies. As carapa as de formato subelíptico, com umbo pequeno e em posi o subanterior s o mantidas emPalaeolimnadiopsis subalata (Reed, 1929) Raymond, 1946. As carapa as subcirculares com umbo pequeno em posi osubcentral correspondem a Palaeolimnadiopsis riorastensis sp. nov. As valvas de formato elíptico com umbo grande eanterior s o atribuídas à Falsisca brasiliensis sp. nov., da Família Perilimnadiidae. O gênero Palaeolimnadiopsis tem umaampla distribui o cronoestratigráfica, porém o gênero Falsisca está restrito ao Permiano superior – Triássico inferior, daEuropa e da ásia. Este intervalo está de acordo com a provável idade permiana superior dos estratos onde foram encontradosestes fósseis na Forma o Rio do Rasto. O gênero Falsisca é aqui referido pela primeira vez ao registro fóssil do Gondwana.
Resource Use of Wind Farms in the German North Sea—The Example of Alpha Ventus and Bard Offshore I
Klaus Wiesen,Jens Teubler,Holger Rohn
Resources , 2013, DOI: 10.3390/resources2040504
Abstract: The German government aims to obtain at least 40 percent of its electricity from renewable sources by 2030. One of the central steps to reach this target is the construction of deep sea offshore wind farms. The paper presents a material intensity analysis of the offshore wind farms “Alpha Ventus” and “Bard Offshore I” under consideration of the grid connection. An additional onshore scenario is considered for comparison. The results show that offshore wind farms have higher resource consumption than onshore farms. In general, and in respect to the resource use of other energy systems, both can be tagged as resource efficient.
Authentification of Einstein’s Static Universe of 1917  [PDF]
Eli Peter Manor
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.518194
Abstract: Static cosmology has been abandoned almost a century ago because of phenomena which were unexplained at those times. However, that scenario can be revived with the modern findings of gravitational forces, coming from outside of the “luminous world”, tugging on our universe. These unexplained phenomena were: the redshift, the CMB, and Olbers’ paradox. All these can now be explained, as done in the present manuscript. 1) The observed redshift, which is commonly attributed to the Doppler effect, can also be explained as a gravitational redshift. Thus, the universe is not expanding, as has also been described in recent publications, thereby, making the “Big Bang” hypothesis unnecessary. 2) Gravitation is induced by matter, and at least some of the distant matter is expected to be luminous. That electro-magnetic emission is extremely redshifted, and thus perceived by us as CMB. CMB is not necessarily a historic remnant related to the “Big Bang”, rather it is the redshifted light, coming from extremely distant luminous matter. 3) According to Olbers’ paradox, the night sky is expected to be bright. The sky looks dark because the light coming from extremely faraway light sources, out of our visible universe, is extremely redshifted. Therefore it is perceived by us as CMB. As in the cosmological literature many problems with the “Big Bang” hypothesis have been described, where as the problems with the static universe model are resolved in the present manuscript, the static state scenario should be renovated.
Gravity, Not Mass Increases with Velocity  [PDF]
Eli Peter Manor
Journal of Modern Physics (JMP) , 2015, DOI: 10.4236/jmp.2015.610145
Abstract: There are controversies and misunderstandings with the term “relativistic mass”. So, alternative concepts must be considered. It is postulated herewith that the stronger force required to accelerate an object moving at a faster speed is due to the increase of its inertia. That ensues in a rise in the gravitational force required to pull that object, and thereby brings to an increase in the gravitational constant. In this paper a formula is derived to calculate these variations in the gravitational constant, which is: \"\". This makes the use of the term “relativistic mass” unnecessary.
Quark Oscillation Causes Gravity  [PDF]
Eli Peter Manor
Journal of Modern Physics (JMP) , 2016, DOI: 10.4236/jmp.2016.75043
Abstract: Quark movement is almost by the speed of light. Due to this speed their inertial mass-effect increases profoundly. That inertial effect is an accelerating force. Within the nucleon the force is the strong force. As quarks movements are back and forth movements, called zigzag or oscillating movements, there is movement in opposite directions. So the oppositely acting forces annihilate each other. However the force acting on objects receding from each other is a trifle stronger than that acting on objects approaching each other. This small difference between these forces is a “left over” force and “leaks” out of the nucleon. In previous manuscripts, formulae were presented to calculate these forces. In the present paper the “left over”, “leaking” force is estimated, and this force is gravity.
Context-Dependent Recognition Is Related to Specific Processes Taking Place at Encoding and at Retrieval  [PDF]
Tamar Silberg, Eli Vakil
Psychology (PSYCH) , 2017, DOI: 10.4236/psych.2017.83020
Abstract: Context Effect (CE) refers to the facilitation of memory for target information due to the similarity of contextual information available during both learning and retrieval. Many studies have attempted to identify variables that influence this effect, producing inconsistent findings due to differences in how target and context information are defined and measured. In the current study, recognition memory for faces was tested under different learning instructions and diverse context-recognition conditions. When memory instructions were used, recognition rates proved higher for the original target-context pairs than for all other possible target-context conditions. A different CE profile was observed for attentional instructions while old, yet not necessarily original, target-context faces yielded better results than other context conditions. These findings indicate that memory instructions lead to CE based on the formation of a specific association between target and context information, while instructions focusing on attentional resources lead to CE based on familiarity judgments. The double dissociation reported here is that memory instructions yield binding as opposed to familiarity type of CE, while attention instructions yield familiarity and not binding type of CE, supporting the claim that CE is not homogeneous and involves a number of cognitive processes.
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