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Search Results: 1 - 10 of 759 matches for " Eleni-Rosalina Andrinopoulou "
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Dynamic Predictions with Time-Dependent Covariates in Survival Analysis using Joint Modeling and Landmarking
Dimitris Rizopoulos,Magdalena Murawska,Eleni-Rosalina Andrinopoulou,Geert Molenberghs,Johanna J. M. Takkenberg,Emmanuel Lesaffre
Statistics , 2013,
Abstract: A key question in clinical practice is accurate prediction of patient prognosis. To this end, nowadays, physicians have at their disposal a variety of tests and biomarkers to aid them in optimizing medical care. These tests are often performed on a regular basis in order to closely follow the progression of the disease. In this setting it is of medical interest to optimally utilize the recorded information and provide medically-relevant summary measures, such as survival probabilities, that will aid in decision making. In this work we present and compare two statistical techniques that provide dynamically-updated estimates of survival probabilities, namely landmark analysis and joint models for longitudinal and time-to-event data. Special attention is given to the functional form linking the longitudinal and event time processes, and to measures of discrimination and calibration in the context of dynamic prediction.
The Role of Muscle Loading on Bone (Re)modeling at the Developing Enthesis
Alexander M. Tatara, Justin H. Lipner, Rosalina Das, H. Mike Kim, Nikunj Patel, Eleni Ntouvali, Matthew J. Silva, Stavros Thomopoulos
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0097375
Abstract: Muscle forces are necessary for the development and maintenance of a mineralized skeleton. Removal of loads leads to malformed bones and impaired musculoskeletal function due to changes in bone (re)modeling. In the current study, the development of a mineralized junction at the interface between muscle and bone was examined under normal and impaired loading conditions. Unilateral mouse rotator cuff muscles were paralyzed using botulinum toxin A at birth. Control groups consisted of contralateral shoulders injected with saline and a separate group of normal mice. It was hypothesized that muscle unloading would suppress bone formation and enhance bone resorption at the enthesis, and that the unloading-induced bony defects could be rescued by suppressing osteoclast activity. In order to modulate osteoclast activity, mice were injected with the bisphosphonate alendronate. Bone formation was measured at the tendon enthesis using alizarin and calcein fluorescent labeling of bone surfaces followed by quantitative histomorphometry of histologic sections. Bone volume and architecture was measured using micro computed tomography. Osteoclast surface was determined via quantitative histomorphometry of tartrate resistant acid phosphatase stained histologic sections. Muscle unloading resulted in delayed initiation of endochondral ossification at the enthesis, but did not impair bone formation rate. Unloading led to severe defects in bone volume and trabecular bone architecture. These defects were partially rescued by suppression of osteoclast activity through alendronate treatment, and the effect of alendronate was dose dependent. Similarly, bone formation rate was increased with increasing alendronate dose across loading groups. The bony defects caused by unloading were therefore likely due to maintained high osteoclast activity, which normally decreases from neonatal through mature timepoints. These results have important implications for the treatment of muscle unloading conditions such as neonatal brachial plexus palsy, which results in shoulder paralysis at birth and subsequent defects in the rotator cuff enthesis and humeral head.
Women’s issues: Dominican single-parent families in Barcelona and New York Cosas de mujeres: familias monoparentales dominicanas en Barcelona y Nueva York
Rosalina Alcalde
Revista Internacional de Organizaciones , 2011,
Abstract: Several international and Spanish studies have shown that one-parent families are at considerable risk of poverty in contemporary and developed societies, particularly when the mother is the head, which is usually the case. This paper provides the main results of some research carried out in Barcelona and New York about one-parent families and immigrant women, with particular emphasis on Dominican women. Numerosos estudios a escala internacional y espa ola avalan en la actualidad el riesgo de pobreza que presentan los hogares monoparentales encabezados por mujeres en las sociedades contemporáneas desarrolladas. Este artículo recoge algunos de los principales resultados de sendas investigaciones llevadas a cabo en las ciudades de Barcelona y Nueva York sobre la incidencia de estas formas de hogar entre las mujeres inmigrantes, focalizando el análisis en las mujeres dominicanas.
Effect of Storage Conditions on the Sensory Quality, Colour and Texture of Fresh-Cut Minimally Processed Cabbage with the Addition of Ascorbic Acid, Citric Acid and Calcium Chloride  [PDF]
Eleni Manolopoulou, Theodoros Varzakas
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.29130
Abstract: The aim of this study was to investigate the effect of storage conditions on the sensory quality, colour and texture of fresh-cut cabbage during the addition of ascorbic acid, citric acid and calcium chloride. Ascorbic acid maintained the overall quality for 14 days at 0℃ and 7 days at 5℃; no difference, however, was observed regarding browning of cut surface compared to the control sample at both storage temperatures. Calcium chloride maintained the overall quality and cut surface browning for 14 days at both storage temperatures. It was also found that citric acid 1% can be used for minimally processed cabbage. Soaking with citric acid helped retain the color and increased the overall acceptance and organoleptic quality of fresh cut cabbage; it reduced browning of the cut surface and protected against formation of black specks. Citric acid treatment combined with low temperature storage (0℃) prolonged the shelf life of minimally processed cabbage for 22 days, time sufficient for acceptable marketing of the product. The lightness of minimally processed cabbage decreased linearly from 70.94 ± 6 to 63.8 ± 8.5 - 61.3 ± 8 units for the chemical treatments during 22 days of storage at 0℃. Hue angle values during storage time were also significantly influenced by chemical treatments mainly at 0℃.
School Effects on Adolescent Substance Use: Prevention through Interactive and Social Learning Strategies  [PDF]
Eleni Stefanidi, George Tsitsas
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.65050
Abstract: This study aimed to examine: a) the factors in Greek schools that are related to the school course of the adolescent drug abusers; b) the effectiveness of new interactive and social learning strategies in preventing drug use. Data were drawn from a face-to-face survey carried out on population of ex-drug abusers that were attending therapeutic programs of STROFI-KETHEA and in other places such as private with psychiatrists. The sample was 22 boys and 8 girls aged 16 to 21 years. All participants had a drug use experience and high rates of school drop out. The results suggest that factors related to the Greek school environment-meaning its culture, sense of community, education strategies–have negatively affected the school course of the participants. The poor school connectedness and dropping out effect negatively on young people’s behavior and drug use problems. Prevention should be considered through a new approach of the education system.
O fracasso escolar: a quem atribuir?
Silva, Rosalina Carvalho da;
Paidéia (Ribeir?o Preto) , 1994, DOI: 10.1590/S0103-863X1994000200004
Abstract: this study discusses how academic failures are being interpreted as psychological problems. 131 were analyzed cases from a public health service at ribeir?o preto, s?o paulo. the predominance was 7-to 12-year-old male cases and the majority of complains (71,4%) were related as learning desabilities and school problems. the school is the main source to guide the cases towards psychological services. although these data confirm others from this area, we are focusing the limited way the educators are interpreting academic failures from children and adolescents as psychological problems.
Budi Hartanto,Silvia Rosalina
Jurnal Informatika , 2006,
Abstract: Original ray tracing method can be used to create picture of objects that are very similar to photographic. However for simplicity, the method mimics a pinhole camera in its model. In pinhole camera all objects visualized in the image generated will be seen sharp. In some cases, this kind of image is acceptable but in other cases it is not. For example, in the movie industry, sometimes it is preferable to get the image that can be focused to a certain object and not to all objects. This effect occurs due to the usage of a lens in a camera. In order to get the same effect to the real camera, then it is necessary to modify the original ray tracing method to use lens in its model. The research performed here has successfully simulating the effect of lens in camera. Therefore only objects that are placed in the lens focus will be seen sharp while the others will become blurry.
REVIEW: Postwar Japanese Economy and Southeast Asia (Hideo Kobayashi)
Rosalina Palanca-Tan
Kasarinlan : Philippine Journal of Third World Studies , 2005,
New Agents Targeting Angiogenesis in Glioblastoma
Eleni Timotheadou
Chemotherapy Research and Practice , 2011, DOI: 10.1155/2011/878912
Abstract: Glioblastoma is the most common malignant glioma in adults, and despite recent advances in standard treatment, the prognosis still remains dismal, with a median survival of 15 months. The incorporation of bevacizumab in the standard treatment of relapsed glioblastoma has been a significant step towards combining targeted agents with chemotherapy, and there is an increasing number of new antiangiogenic agents in various stages of development, that are being tested both in relapsed and newly diagnosed disease, alone or in combination with standard treatment. The relatively favorable toxicity profile for most of them presents an advantage, but several concerns arise regarding their actual efficacy on the clinical level and the most efficient schedule of administration for each of them, as their molecular targets and patterns of action may vary significantly. This may lead to future modifications of the current rational of administering these agents concomitantly with initial chemotherapy or maintenance treatment.
Os refugos do mundo: figuras do pária
Varikas, Eleni;
Estudos Avan?ados , 2010, DOI: 10.1590/S0103-40142010000200003
Abstract: from the 16th to the 18th centuries, the term pariah, coined by western travelers, imperial officials or missionaries to designate the abjection of the outcasts in india, circulated in portuguese, english, french, german and dutch literati circles. in the discourse of enlightenment - and throughout the 19th century - it acquires a new meaning, related to the increasingly pejorative connotation of "caste". the metaphor of the "pariah" provides thus an idiom of the critique of arbitrary authority and the persisting social and political exclusion. thanks to the literature, theater, and opera, it enters the european literary and plebeian public spaces, giving a name to the modern invisible hierarchies, and denouncing the dehumanizing construction of the other in a world claiming as its grounding principle the universality of human rights.
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