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Search Results: 1 - 10 of 206216 matches for " Edward P.; Chemodurow "
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A pre- post-evaluation of implementing an inpatient warfarin monitoring and education program
Armstrong,Edward P.; Chemodurow,Lucy; Christensen,Shanna; Johnson,E. Suzanne;
Pharmacy Practice (Internet) , 2011, DOI: 10.4321/S1886-36552011000200007
Abstract: objective: the purpose of this study was to evaluate whether a new anticoagulation management program resulted in better monitoring of warfarin, increased warfarin patient education prior to discharge, and fewer bleeding complications associated with warfarin. methods: a retrospective chart review was conducted of patients who were inpatients and received warfarin from april 1, 2008 to july 31, 2008 (control group) and from april 1, 2009 to july 31, 2009 (after implementation of the new anticoagulation program). the frequency of warfarin-related laboratory orders that included international normalized ratios (inrs), complete blood counts (cbcs), and documented patient education by pharmacy, nursing, and dietary services were determined before and after program implementation. also, data was collected to determine frequencies of bleeding complications associated with warfarin. results: there were 112 patients in the pre- and 115 patients in the post-program group. after implementation of the inpatient warfarin management program, obtaining baseline inrs increased from 74% to 90% (p=0.001). orders for baseline cbcs increased from 85% to 94% (p=0.026). obtaining cbcs every 3 days increased from 54% to 74%, (p<0.001). however, there was no significant change in orders for daily inrs (p=0.055). education by nursing increased from 54% to 80%, (p<0.001), by pharmacy increased from 8% to 76%, (p<0.001), and by dietary increased from 11% to 79%, (p<0.001). documentation by all three disciplines in each patient increased from 3.6% to 59%, (p<0.001). significantly fewer patients received vitamin k and/ or fresh frozen plasma for supratherapeutic inrs with bleeding complications after the program was initiated compared to baseline (p=0.009). conclusion: the implementation of an inpatient warfarin management program led to better monitoring of patients receiving warfarin, and increased patient education. however, a larger and longer assessment is necessary to determine if these
A Cognitive Emotional Methodology for Critical Thinking  [PDF]
Edward P. Hanna
Advances in Applied Sociology (AASoci) , 2013, DOI: 10.4236/aasoci.2013.31003
Abstract: This essay provides a theoretical foundation for a cognitive emotional methodology for critical thinking that is currently being utilized by the author in undergraduate and graduate social work advanced seminar classes. Through a review of the literature, the paper suggests that most approaches to teaching critical thinking do not integrate cognitive emotional criteria in the teaching method, and this is problematic for social work education. Citing recent literature about teaching empathy and values, and merging that work with clinical theory and practice, a theoretical foundation is established for a methodology that is in its formative stages. The methodology and its constructs are described. Although the methodology is presented though the vehicle of social work education, it is asserted that the methodology has broader utility.


Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response
Edward P. Browne
PLOS Pathogens , 2011, DOI: 10.1371/journal.ppat.1002293
Abstract: The development of vaccines that can enhance immunity to viral pathogens is an important goal. However, the innate molecular pathways that regulate the strength and quality of the immune response remain largely uncharacterized. To define the role of Toll-like receptor (TLR) signaling in control of a model retroviral pathogen, Friend virus (FV), I generated mice in which the TLR signaling adapter Myd88 was selectively deleted in dendritic cell (DC) or in B cell lineages. Deletion of Myd88 in DCs had little effect on immune control of FV, while B cell specific deletion of Myd88 caused a dramatic increase in viral infectious centers and a significantly reduced antibody response, indicating that B cell-intrinsic TLR signaling plays a crucial role, while TLR signaling in DCs is less important. I then identified the single-stranded RNA sensing protein TLR7 as being required for antibody-mediated control of FV by analyzing mice deficient in TLR7. Remarkably, B cells in infected TLR7-deficient mice upregulated CD69 and CD86 early in infection, but failed to develop into germinal center B cells. CD4 T cell responses were also attenuated in the absence of TLR7, but CD8 responses were TLR7 independent, suggesting the existence of additional pathways for detection of retroviral particles. Together these results demonstrate that the vertebrate immune system detects retroviruses in vivo via TLR7 and that this pathway regulates a key checkpoint controlling development of germinal center B cells.
Magnetic Biotransport: Analysis and Applications
Edward P. Furlani
Materials , 2010, DOI: 10.3390/ma3042412
Abstract: Magnetic particles are finding increasing use in bioapplications, especially as carrier particles to transport biomaterials such as proteins, enzymes, nucleic acids and whole cells etc. Magnetic particles can be prepared with biofunctional coatings to target and label a specific biomaterial, and they enable controlled manipulation of a labeled biomaterial using an external magnetic field. In this review, we discuss the use of magnetic nanoparticles as transport agents in various bioapplications. We provide an overview of the properties of magnetic nanoparticles and their functionalization for bioapplications. We discuss the basic physics and equations governing the transport of magnetic particles at the micro- and nanoscale. We present two different transport models: a classical Newtonian model for predicting the motion of individual particles, and a drift-diffusion model for predicting the behavior of a concentration of nanoparticles that takes into account Brownian motion. We review specific magnetic biotransport applications including bioseparation, drug delivery and magnetofection. We demonstrate the transport models via application to these processes.
Funding constrains PhD production
Edward P. Rybicki
South African Journal of Science , 2011, DOI: 10.4102/sajs.v107i7/8.798
Abstract:
On a New Species of Pediopsis
Edward P. Van Duzee
Psyche , 1889, DOI: 10.1155/1889/58075
Abstract:
Mimicry in Hemiptera
Edward p. van Duzee
Psyche , 1888, DOI: 10.1155/1888/62627
Abstract:
Periodic solutions of a one Dimensional Wilson-Cowan type model
Edward P. Krisner
Electronic Journal of Differential Equations , 2007,
Abstract: We analyze a time independent integral equation defined on a spatially extended domain which arises in the modeling of neuronal networks. In our survey, the coupling function is oscillatory and the firing rate is a smooth "heaviside-like" function. We will derive an associated fourth order ODE and establish that any bounded solution of the ODE is also a solution of the integral equation. We will then apply shooting arguments to prove that the ODE has two "1-bump" periodic solutions.
Homoclinic orbit solutions of a one Dimensional Wilson-Cowan type model
Edward P. Krisner
Electronic Journal of Differential Equations , 2008,
Abstract: We analyze a time independent integral equation defined on a spatially extended domain which arises in the modelling of neuronal networks. In this paper, the coupling function is oscillatory and the firing rate is a smooth "heaviside-like" function. We will derive an associated fourth order ODE and establish that any bounded solution of the ODE is also a solution of the integral equation. We will then apply shooting arguments to prove that the ODE has N-bump homoclinic orbit solutions for any even-valued N>0. homoclinic orbit.
Unleashing the Potential of Collaborative Governance Arrangements: Getting to Robust Durability in the Blackfoot Valley
Edward P. Weber
Journal of Sustainable Development , 2012, DOI: 10.5539/jsd.v5n7p35
Abstract: If collaborative governance arrangements are something to be valued and if they can help us to improve our ability to resolve collective action problems, then it behooves scholars to develop a good understanding of the elements associated with institutional durability. This paper focuses on the concept of robust durability because it captures the importance of problem-solving effectiveness as well as institutional durability. The problem, of course, is that the puzzle of durability is a difficult one to unlock given that collaboration is hard to do and robust durability even harder. The award winning, highly successful Blackfoot Challenge case of collaborative watershed management in Montana, however, offers lessons about robust durability across almost two decades. The lessons involve more than just institutional design, appropriate antecedent conditions, and a supportive external environment. Instead there are a series of variables wrapped up in the operational dynamic inside the collaborative that appear to matter most. Robust durability in the case of the Challenge relies on the character of the organization, continuity of leadership, a multi-faceted managerial strategy, and the application of a systematic fiscal strategy.
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